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| Number | Title | Issue Date |
| 7318966 | Luminescent element material and luminescent element comprising the same A light emitting device includes an emissive substance between an anode and cathode that emits light upon application of electrical energy. The emissive substance included in the device is at least one of the following types of compounds: (a) a compound having a plu... | 01/15/2008 |
| 7276343 | Chemiluminescence enhancer The present invention provides a chemiluminescence enhancer treated to retain favorable dispersibility of fine solid carriers and stably exert a chemiluminescence enhancing action. The invention provides a chemiluminescence enhancer used for signal detection in a so... | 10/02/2007 |
| 7273933 | Methods for synthesis of oligonucleotides Improved methods for synthesis of oligonucleotides and other phosphorus-linked oligomers are disclosed. The methods include the use of aromatic solvents, alkyl aromatic solvents, halogenated aromatic solvents, halogenated alkyl aromatic solvents, or aromatic ether s... | 09/25/2007 |
| 7199236 | Process for the synthesis of oligomeric compounds Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related cont... | 04/03/2007 |
| 7057062 | Process for manufacturing purified phosphorodiamidite A scalable process for purification of phosphorodiamidite includes steps of solubilizing a crude phosphorodiamidite in an apolar organic solvent, contacting the non-polar organic solvent with a polar phase comprising a polar organic solvent to remove impurities from... | 06/06/2006 |
| 7049432 | Oligonucleotides having alkylphosphonate linkages and methods for their preparation The present invention provides alkylphosphonate dimers and oligonucleotides prepared therefrom. The invention further provides novel methods for the preparation of these alkylphosphonate dimers. Methods for the preparation of substantially diastereomerically pure al... | 05/23/2006 |
| 7041816 | Process for the synthesis of oligomeric compounds Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related cont... | 05/09/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 7034177 | Process of making phosphordiamidite compounds A process of producing cyanoalkyl tetraalkylphosphordiamidites at least substantially free of amine hydrohalide with improved storage stability. ... | 04/25/2006 |
| 6919437 | Synthetic methods and intermediates for triester oligonucleotides Methods for the preparation of oligonucleotides having bioreversible phosphate blocking groups are disclosed. In one aspect, the present invention provides compounds comprising a sequence of nucleotide units that includes a first segment having at least one internuc... | 07/19/2005 |
| 6914148 | Guanidinium functionalized intermediates The present invention provides oligomers which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligomer is modified to include a guanidinium group. These oligomers are useful for diagnostic,... | 07/05/2005 |
| 6911595 | Charge transfer material, and photoelectric conversion device and photoelectric cell using same, and pyridine compound A charge transfer material comprising a basic compound having negative charge and represented by the following general formula (I): (A1-L)n1-A2·M (I), wherein A1 represents a group having negativ... | 06/28/2005 |
| 6710149 | Hydrolysis-stable and polymerizable acrylophosphonic acid Hydrolysis-stable and polymerizable acrylophosphonic acid with the general formula (I) which is particularly suitable as a component of dental materials is disclosed. ... | 03/23/2004 |
| 6576159 | Malononitrile-derivative anion salts, and their uses as ionic conducting materials The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M+m in... | 06/10/2003 |
| 6333425 | Malononitrile-derivative anion salts, and their uses as ionic conducting materials The invention is related to ionic compounds, derivatives of malononitrile, in which the anionic load has been displaced. An ionic compound disclosed by the invention includes an anionic portion combined with at least one cationic portion M+m in... | 12/25/2001 |
| 6287767 | Chemiluminescent energy transfer assays A chemiluminescent assays for the determination of the presence or amount of a biopolymer in bound assays using 1,2-dioxetanes in connection with AttoPhos™ as chemiluminescent substrates for enzyme-labeled targets or probes is provided. Further disclose... | 09/11/2001 |
| 6278012 | Process for preparing phosphinate esters The present invention relates to a process for the preparation of phosphinic acid esters, which comprises a) reacting elemental yellow phosphorus with alkylating agents in the presence of a base to give a mixture which comprises, as principal constituents... | 08/21/2001 |
| 6255518 | Preparation of fluorinated compounds A method for the preparation of a fluorinated Phosphonate having the formula (RO)2 PO CFR'R" comprises treating a phosphonate of the formula (RO)2 PO CHR'R", or a metal salt thereof, with fluorine. R is an alkyl group R' is hydrogen ... | 07/03/2001 |
| 6245928 | Water soluble tri-substituted 1,2-dioxetane compounds having increased storage stability, synthetic processes and intermediates Stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility and storage stability are provided as well as synthetic processes and intermediates used in their preparation. Dioxetanes further substituted with two or more w... | 06/12/2001 |
| 6130211 | Phosphocholinate cardenolides Disclosed herein are cardenolides and related compounds covalently linked to phosphocholine moieties and pharmaceutical formulations comprising such compounds. Also disclosed herein are methods for treating hypertension, premenstrual syndrome (PMS), preec... | 10/10/2000 |
| 5990337 | Process for the preparation of 2-cyanoethylphosphinic esters The invention relates to a process for the preparation of phosphorus-containing compounds of the formula (I) ##STR1## where R1 and R2 are identical or different and are a straight-chain or branched alkyl radical having 1 to 8 ca... | 11/23/1999 |
| 5935542 | Cyanphosphonate derivatives and method for their preparation The novel cyanophosphonate compounds of the present invention include cyanophosphonate salts, cyanophosphonate monoacid salts, cyanophosphonate monoacid esters, cyanophosphonate monoester salts and cyanophosphonate methylester salts.... | 08/10/1999 |
| 5905163 | Method for preparing aminomethylphosphonate derivatives via hydrogenation of cyanophosphonate derivatives A novel process for preparing aminomethylphosphonate derivatives involves the hydrogenation of cyanophosphonate derivatives in the presence of a catalyst to produce aminomethylphosphonate derivatives.... | 05/18/1999 |
| 5861525 | Method for preparing cyanophosphonate derivatives from phosphate esters and cyanide A process for preparing cyanophosphonate derivatives involves contacting a phosphate ester and cyanide in a reaction mixture under conditions sufficient to produce a cyanophosphonate derivative. That cyanophosphonate derivative product can subsequently be... | 01/19/1999 |
| 5858317 | Method for preparing cyanophosphonate derivatives from phosphoric anhydride and cyanide A process for preparing cyanophosphonate derivatives involves contacting phosphoric anhydride (P4 O10) and a cyanide, preferably in the presence of a Lewis base, in a reaction mixture under sufficient conditions to produce a cyanopho... | 01/12/1999 |
| 5859278 | Method for preparing cyanophosphonate derivatives from pyrophosphate or polyphosphate esters and cyanide A process for preparing cyanophosphonate derivatives involves contacting a pyrophosphate ester or a polyphosphate ester and cyanide in a reaction mixture under conditions sufficient to produce the cyanophosphonate derivative. The cyanophosphonate derivati... | 01/12/1999 |
| 5705621 | Oligomeric phosphite, phosphodiester, Phosphorothioate and phosphorodithioate compounds and intermediates for preparing same Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, and phosphorodithioate covalent linkages. Also provided are synthetic intermediates useful in such processes.... | 01/06/1998 |
| 5627173 | Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders Compounds of the formula I ##STR1## are suitable for producing pharmaceuticals for the treatment and prophylaxis of degenerative joint disorders, of rheumatic di... | 05/06/1997 |
| 5610210 | Aminovinylphosphonic ester stabilizers for organic material Aminovinylphosphonic esters I ##STR1## where R1 is cyano, a radical of the formula --CO--OR6 or a group of the formula ##STR2## R2, R3 and R6 are C1 -C20 -alkyl, C... | 03/11/1997 |
| 5576308 | Organophosphorus compounds and insecticides, acaricides and nematocides containing same An insecticidal, acaricidal or nematocidal composition which comprises an organophosphorus compound represented by formula (I): ##STR1## wherein R1, R2 and R3 each represents C1 to C4 alkyl; A re... | 11/19/1996 |
| 5519006 | Phosphonated arylethanolamine compounds with anti-hyperglycemic and/or anti-obesity activity | 05/21/1996 |
| 5468870 | Dyes and dye-donor elements for use in thermal dye sublimation transfer Dye-donor element for use according to thermal dye sublimation transfer comprising a support having thereon a dye layer containing a dye corresponding to the following formula ##STR1## wherein Z represents CN, COOR1 or CONR2 R | 11/21/1995 |
| 5401845 | Asymmetric aryl phosphites Compounds of the formula I ##STR1## in which x is 1, 2 or 3, and, if x=1, R1 is C1 -C30 alkyl, C1 -C18 alkyl substituted by halogen, --COOR2, --CN, --NR3 R4 or by... | 03/28/1995 |
| 5322871 | Asymmetric aryl phosphites Compounds of the formula I ##STR1## in which x is 1, 2 or 3, and, if x=1, R1 is C1 -C30 alkyl, C1 -C18 alkyl substituted by halogen, --COOR2, --CN, --NR3 R4 or by... | 06/21/1994 |
| 5282988 | Lubricant additives A urethane reaction product, derived from an alkoxylated diorgano phosphorodithioate and an isocyanate, specifically, toluenediisocyanate and hexamethylene diisocyanate, is a multifunctional antiwear and antioxidant additive for lubricants. The isocyanate... | 02/01/1994 |
| 5210264 | S-(2,4-dichlorobenzyl)-ଲ-cyanoethyl phosphorothioate diester The compound S-(2,4-dichlorobenzyl)-ଲ-cyanoethyl phosphorothioate diester is disclosed as useful in the synthesis of phosphorothioate oligonucleotides. In certain embodiments of the invention, this reagent is used to prepare 3'-S-(alkaryl) phosphoro... | 05/11/1993 |
| 5206227 | Composition and use of phosphonic acid, (2-halo-2-cyanoethenyl)-dialkyl esters as antimicrobials Phosphonic acid, (2-halo-2-cyanoethylenyl)-dialkylesters are prepared which correspond to the formula: ##STR1## wherein R1 and R2 independently represent an alkyl group and X represents a halogen. These compounds have been found... | 04/27/1993 |
| 5159097 | Alkenoic acid derivatives An alkenoic acid derivative of the formula ##STR1## in which X and Y are identical or different and represent sulfur, sulfoxide, sulfone, an alkylene chain, --SCH2 --, or oxygen or a direct bond, W represents --CH.dbd.CH--or --CH2 | 10/27/1992 |
| 5142085 | Preparation of (cyanofluoromethyl)-phosphonates A process for the preparation of a compound of the formula ##STR1## wherein alk1 and alk2 are individually alkyl of 1 to 8 carbon atoms comprising reacting a compound of the formula ##STR2## with a dehydrating agent to obta... | 08/25/1992 |
| 5142089 | Dyes and dye-donor elements for use in thermal dye sublimation transfer Dye corresponding to the following formula - ##STR1## wherein Z represents CN, COOR1 or CONR2 R3 ; R1, R2 and R3 each independently represents hydrogen, substituted or unsubstituted alkyl, ... | 08/25/1992 |
