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| Number | Title | Issue Date |
| 7541484 | Process for producing phosphate The invention relates to a process for producing a phosphate, which includes reacting a phosphorus pentaoxide-containing phosphorylating agent with an organic hydroxy compound, the reaction being carried out at a reaction temperature of 50 to 70° C. until the degre... | 06/02/2009 |
| 7316902 | Compositions that specifically bind to colorectal cancer cells and methods of using the same A unique transcription product, CRCA-1, and alternative translation products generated therefrom, are disclosed. The transcript and its translation products are markers for colorectal cells. Screening and diagnostic reagents, kits and methods for metastasized colore... | 01/08/2008 |
| 7317103 | Imaging agents for diagnosis of Parkinson's disease Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagn... | 01/08/2008 |
| 7262159 | Odor elimination composition for use on soft surfaces A method and composition for deodorizing soft surfaces such as carpeting and upholstery are disclosed. The method includes the spraying of a liquid composition on a soft surface and allowing the composition to absorb into the soft surface, form liquid agglomerations... | 08/28/2007 |
| 7208452 | Process for manufacturing alkylphosphonate monoesters The present invention discloses a process for manufacturing an alkylphosphonate monoester. The process may comprise partially hydrolyzing an alkyl phosphonate diester with an alkaline compound in a first solvent to provide a reaction mixture, wherein the first solve... | 04/24/2007 |
| 7196213 | Process for producing phosphate Provided are a process for producing a phosphate and a process for stabilizing a phosphate, the phosphate being an acid-form phosphate wherein an organic hydroxy compound is an alkylene oxide adduct. A production process of a phosphate and a stabilization process of... | 03/27/2007 |
| 7135333 | Compositions that specifically bind to colorectal cancer cells and methods of using the same A unique transcription product, CRCA-1, and alternative translation products generated therefrom, are disclosed. The transcript and its translation products are markers for colorectal cells. Screening and diagnostic reagents, kits and methods for metastasized colore... | 11/14/2006 |
| 7071324 | Systems and methods for sequencing by hybridization The systems and methods described herein relate to nucleic acid probes comprising a pattern of universal and designate nucleotides (or analogs thereof), or ‘gapped’ probes, and the use of sets of gapped probes in sequencing by hybridization to determine the sequ... | 07/04/2006 |
| 6953663 | Polymorphism detection The present invention generally provides a rapid efficient method for analyzing polymorphic or biallelic markers, and arrays for carrying out these analyses. In general, the methods of the present invention employ arrays of oligonucleotide probes that are complement... | 10/11/2005 |
| 6908732 | Compounds and methods for regulating cell differentiation The present invention makes available methods and reagents for inhibiting cell growth or promoting cell differentiation comprising contacting the cell with a differeguline in a sufficient amount to inhibit cell proliferation or promote cell differentiation. ... | 06/21/2005 |
| 6855757 | Preparation of glycol carboxyethylmethylphosphinate The invention relates to a process of preparing glycol carboxyethylmethylphosphinate, which comprises a) reacting elemental yellow phosphorus with methyl chloride in the presence of an alkali or alkaline earth metal hydroxide to fo... | 02/15/2005 |
| 6441223 | Method of making phosphorus-containing compounds and products thereof A process for oxidizing a hydroxymethylphosphonic acid compound to produce a formylphosphonic acid compound is described. The oxidation reaction is carried out in the presence of an oxidant and a catalyst. For example, hydroxymethylphosphonic acid (HMPA) ... | 08/27/2002 |
| 6440952 | Phosphono-carboxylate compounds for treating amyloidosis Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising ... | 08/27/2002 |
| 6407277 | Process for the preparation of phosphoric monoester An organic hydroxyl compound is reacted with a phosphorylating agent comprising phosphorus pentaoxide and at least one compound selected from the group consisting of water, phosphoric acid and polyphosphoric acid and having a value represented by formula ... | 06/18/2002 |
| 6319432 | Bisphenol-A bis(diphenyl phosphate)-based flame retardant Disclosed is a flame retardant comprising bisphenol A bis(diphenyl phosphate) and its dimer, the former having an HPLC determined 78 to 87 area % and an 85 to less than 90 normalized area %, the normalized area % being based on the total HPLC area % of th... | 11/20/2001 |
| 6278012 | Process for preparing phosphinate esters The present invention relates to a process for the preparation of phosphinic acid esters, which comprises a) reacting elemental yellow phosphorus with alkylating agents in the presence of a base to give a mixture which comprises, as principal constituents... | 08/21/2001 |
| 6191253 | Polyether phosphates A dispersant for aqueous mill-bases obtainable by reacting a polyethylene glycol with a molar excess of a hydroxycarboxylic acid containing from 4 to 17 carbon atoms or lactone thereof and/or with a C3-4 -alkylene oxide to form a polymeric diol... | 02/20/2001 |
| 6090967 | Process for preparing phosphonous esters The present invention relates to a process for preparing phosphonous esters which comprises a) reacting elemental yellow phosphorus with alkyl halides in the presence of alkali metal hydroxides and/or alkaline earth metal hydroxides to form a mixture whic... | 07/18/2000 |
| 6090968 | Process for preparing phosphinic esters The present invention relates to a process for preparing phosphinic esters which comprises a) reacting elemental yellow phosphorus with alkyl halides in the presence of alkali metal hydroxide or alkaline earth metal hydroxide to form a mixture which compr... | 07/18/2000 |
| 6034261 | Process for the preparation of phosphoric monoester An organic hydroxyl compound is reacted with a phosphorylating agent comprising phosphorus pentaoxide and at least one compound selected from the group consisting of water, phosphoric acid and polyphosphoric acid and having a value represented by formula ... | 03/07/2000 |
| 5883280 | Process for the preparation of phosphoric monoester An organic hydroxyl compound is reacted with polyphosphoric acid under such conditions that the ratio, as defined by formula (1), has a value exceeding 3.2; and phosphorus pentaoxide is added to the reaction product thus obtained in such an amount that th... | 03/16/1999 |
| 5785894 | Dispersant for dispersing particulate solids A dispersant for aqueous mill-bases obtainable by reacting a polyethylene glycol with a molar excess of a hydroxycarboxylic acid containing from 4 to 17 carbon atoms or lactone thereof and/or with a C3-4 -alkylene oxide to form a polymeric diol... | 07/28/1998 |
| 5783690 | Protecting group for synthesizing oligonucleotide analogs A 2-N-amidoethyl protected nucleoside analog phosphoramidite of formula (1): ##STR1## is useful in the synthesis of a wide variety of oligonucleotide analogs. Coupling yields with phosphoramidite (1) in solution or solid phase oligonucleotide an... | 07/21/1998 |
| 5554781 | Monoalkyl phosphonic acid ester production process The invention relates to a process for producing a unique phosphation reagent and to a simple, single-stage process utilizing this reagent to produce alkyl phosphate esters having high monoalkyl phosphate content in combination with low dialkyl phosphate,... | 09/10/1996 |
| 5550274 | In-situ phosphation reagent process The invention relates to a simple, single-stage process to produce alkyl phosphate esters having high monoalkyl phosphate content in combination with low dialkyl phosphate, trialkyl phosphate, phosphoric acid and other nonionic (usually residual alcohol) ... | 08/27/1996 |
| 5502231 | Process for the preparation of cyclic vinylphosphonic esters The present invention relates to a process for the preparation of compounds of the general formula I ##STR1## in which R1 and R2 are defined as stated in claim 1, characterized in that a 1,1,1-tris(hydroxymethyl)-(C2 ... | 03/26/1996 |
| 5463101 | Process of making low dioxane alkoxylate phosphate esters This invention relates to first stage phosphation processes which utilize a unique phosphation reagent that esterifies ethoxylated alcohols under mild reaction conditions, thus realizing reduced initial 1,4-dioxane production followed by formation of a di... | 10/31/1995 |
| 5420328 | Methods for the synthesis of phosphonate esters Phsophonate esters can be synthesized in high yields by condensations of alcohols with methyl phosphonates followed by selective demethylation. The reaction is general, relativly insensitive to steric constraints of hindered phosphonic acids, and can also... | 05/30/1995 |
| 5359115 | Methods for the synthesis of phosphonate esters Phosphonate esters can be synthesized in high yields by condensations of alcohols with methyl phosphonates followed by selective demethylation. The reaction is general, relatively insensitive to steric constraints of hindered phosphonic acids, and can als... | 10/25/1994 |
| 5357037 | Phosphorous-containing duromers of oligophosphites This invention relates to new phosphorus-containing duromers of oligophosphites and epoxides or bisacrylates or unsaturated polyesters.... | 10/18/1994 |
| 5344951 | Production of alkyl phosphites This invention relates to an improved process for producing diesters of phosphorous acid. The process comprises (a) reacting phosphorous acid with monohydric alcohol in a petroleum distillate solvent while maintaining a reaction mass temperature within th... | 09/06/1994 |
| 5334741 | Phosphorylation with monomeric metaphosphates Solid substrates with free hydroxyl groups are phosphorylated by thermolysing a solution of phosphoramidate of the formula ##STR1## in the presence of the substrate, whereby metaphosphate is generated which phosphorylates the substrate.... | 08/02/1994 |
| 5306840 | Process for preparing pure L--glycerylphosphoryl-D-myoinositol and its salts A process for preparing pure L-alpha-Glycerylphosphoryl-D-Myoinositol and its salts consists of a) preparing the crude Na+ or K+ salt of L--Glycerylphosphoryl-D-Myoinositol, passing an aqueous solution of the salt through an acid resin in H form wh... | 04/26/1994 |
| 5281741 | Process for preparing aryldiphosphate esters A process is provided for preparing an aryl diphosphate ester containing less than 5% by weight of triarylphosphate. The process reacts a solution of a dihydroxy aromatic compound and an excess of phosphorus oxychloride in a nonaqueous solvent having a bo... | 01/25/1994 |
| 5138084 | Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives A process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives by treatment of a mixture of both 3-O-phosphate and 4-O-phosphate isomers with a strong mineral acid and optional esterification of the so obtained phosphoric ester of do... | 08/11/1992 |
| 5097056 | Process for the preparation of triaryl phosphates using H3 PO4 and hard cation as a catalyst A process is described according to which triaryl phosphates are prepared by the reaction of one or more phenols with H3 PO4, in the presence of a hard cation as a catalyst. Novel catalysts and catalyst precursors for this purpose ar... | 03/17/1992 |
| 4874883 | Process for the production and isolation of monoalkyl phosphoric acid esters In the production of monoalkylphosphoric acid esters, at least one fatty alcohol or mixtures of fatty alcohols containing from 8 to 18 carbon atoms and preferably from 12 to 14 carbon atoms in a straight chain is/are reacted with a 0.2 to 2 molar excess o... | 10/17/1989 |
| 4670575 | Process for purification of phosphoric mono esters A novel process for producing a phosphoric monoester which comprises reacting per 1 mole of a linear or branched, saturated or non-saturated aliphatic alcohol having from 8 to 36 carbon atoms, from 2 to 10 moles of a polyphosphoric acid at 100 to 116% con... | 06/02/1987 |
| 4559184 | Phosphate ester synthesis without phosphorylation catalyst Triarylphosphates are prepared by phosphorylation of alkylphenols without use of phosphorylation catalyst. An improved phosphorylation step includes preheating alkylphenol feedstock to 150° C. and completing reaction at 215° C. or above in the presence ... | 12/17/1985 |
| 4532084 | Method for preparing a methylene-bis-(O,O-diorganophosphorodithiato)-substituted hindered phenol Method for making methylene-bis-diorganophosphorodithiato-substituted hindered phenols by conversion of hindered phenols to the corresponding hindered phenol aldehydes and subsequent reaction, without isolation, with a diorganophosphorodithioic acid, whic... | 07/30/1985 |
