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| Number | Title | Issue Date |
| 8067627 | Zinc-monocysteine complex and method of using zinc-cysteine complexes A method of providing zinc to a subject in need of treatment includes administering to the subject an effective amount of a zinc-cysteine complex. The zinc-cysteine complex is preferably a zinc-monocysteine complex. The complexes of zinc-cysteine of the present inve... | 11/29/2011 |
| 7652161 | Zinc-monocysteine complex and method of using zinc-cysteine complexes A method of providing zinc to a subject in need of treatment includes administering to the subject an effective amount of a zinc-cysteine complex. The zinc-cysteine complex is preferably a zinc-monocysteine complex. The complexes of zinc-cysteine of the present inve... | 01/26/2010 |
| 7375243 | Method for preparation of amino acid chelate The present invention provides methods for preparation of metallic amino acid chelates that are electrically neutral and free of interfering ions, by reacting a metal carbonate and an acidic amino acid in an aqueous solution, and the uses of said metallic amino acid... | 05/20/2008 |
| 7164035 | Zinc-monocysteine complex and method of using zinc-cysteine complexes A method of providing zinc to a subject in need of treatment includes administering to the subject an effective amount of a zinc-cysteine complex. The zinc-cysteine complex is preferably a zinc-monocysteine complex. The complexes of zinc-cysteine of the present inve... | 01/16/2007 |
| 7141689 | Metal complexes of alpha amino dicarboxylic acids Neutral alpha amino diacid complexes of trace minerals and their use for animal nutrition. ... | 11/28/2006 |
| 6992203 | Metal complexes produced by Maillard Reaction products A method is disclosed for the formation of metal chelates which are able to remain stable in high alkaline environments when compared to metal chelates produced from a reaction with amino acids. The method involves the reaction of sugars, amino groups, and metal com... | 01/31/2006 |
| 6911550 | Derivatives of seleno-amino acids with improved bioavailability and method for their preparation Metal L-seleno-alpha-amino acids salts and their use as a bioavailable feed and water ration supplement for domesticated animals such as cattle, pigs and poultry. ... | 06/28/2005 |
| 6770588 | Reduction of carbonyl compounds by a silane in the presence of a zinc catalyst A reductive system including a silane, preferably PMHS, and an active zinc compound, which is monomeric and not a hydride, wherein a reduction of a carbonyl substrate to a corresponding alcohol is achievable. ... | 08/03/2004 |
| 6710079 | Composition and method for preparing amino acid chelates and complexes free of interfering complex ions A composition and method of preparing amino acid chelates and complexes free of interfering ions by blending an amino acid ligand, a calcium oxide and/or hydroxide, and a hydrated metal sulfate salt, placing the blend in a closed environment, heating the blend, and ... | 03/23/2004 |
| 6703498 | Water-soluble polymeric metal ion affinity compositions and methods for using the same Water-soluble metal ion affinity compounds and methods for using the same are provided. The subject compounds include an aspartate based metal chelating ligand bonded to a water-soluble polymeric substrate, where the ligand is complexed with a metal ion. ... | 03/09/2004 |
| 6670494 | Method for preparation of metal organic acid chelates A method is disclosed where organic acid chelates can be made by reacting an organic acid ligand with a metal compound in a non aqueous environment. The chelate is thereafter recovered by means of filtration or evaporation.... | 12/30/2003 |
| 6586611 | Zinc-monocysteine complex and method of using zinc-cysteine complexes A method of providing zinc to a subject in need of treatment includes administering to the subject an effective amount of a zinc-cysteine complex. The zinc-cysteine complex is preferably a zinc-monocysteine complex. The complexes of zinc-cysteine of the p... | 07/01/2003 |
| 6579904 | Process for making betaine transition metal complexes for use in animal feed supplements and compositions thereof Betaine transition metal complexes are formed by: a) reacting a solution including an alkali metal salt of chloroacetic acid with a solution including the transition metal salt to give a solution including a chloroacetate transition metal complex; and b) ... | 06/17/2003 |
| 6573395 | Enantioselective reduction of ketones with a silane agent/metal compound/ chiral ligand system A process for the enantioselective reduction of prochiral ketones to chiral alcohols by (a) the reaction of a prochiral ketone with a silane agent, which is present in a stoichiometric quantity, in the presence of a catalyst derived from a Zn, Co or Cd pr... | 06/03/2003 |
| 6458981 | Composition and method for preparing amino acid chelate hydroxides free of interfering ions The present invention relates to compositions and methods of preparing amino acid chelates that are essentially free of interfering ions. The composition is prepared by reacting in an aqueous solution, a calcium oxide and/or hydroxide, an amino acid, and ... | 10/01/2002 |
| 6426424 | Composition and method for preparing granular amino acid chelates and complexes Compositions and methods of preparing amino acid chelates and complexes are disclosed and described. Specifically, by (a) blending hydrated metal sulfate salts, amino acid ligands, and reaction modifiers; (b) confining the particulate blend in an enclosed... | 07/30/2002 |
| 6380392 | Ligands based on chiral 2-amino-2'-hydroxy-1,1'-binaphthyl and related frameworks for asymmetric catalysis The present invention includes array of new chiral ligands that are optically active or racemic. These ligands are bidentate, tridentate, tetradentate or pentadentate ligands which include P-P, P-N, N-N, mixed P-N, Schiff base or carbene sites. The presen... | 04/30/2002 |
| 6380278 | Polyurethane salts A urethane (meth)acrylate metal salt obtained by reacting (A) one or more polyisocyanates, (B) one or more hydroxy functional (meth)acrylates, and (C) one or more metal salt polyols which are the reaction product of a metal oxide and a half ester containi... | 04/30/2002 |
| 6323354 | Amino acid chelates from lipoproteins A method of preparing amino acid transition metal chelates a palatable highly bioavailable source of transition metals for animal nutrition from lipoproteins and transition metal salts. The method requires strong aqueous base hydrolysis of the lipoprotein... | 11/27/2001 |
| 6245952 | Reduction of carbonyl compounds by a silane in the presence of a zinc catalyst The present invention relates to a process for the preparation of alcohols by reduction of the carbonyl function in substrates belonging to the class of aldehydes, ketones, esters or lactones, which substrates may contain unsaturated functions other than ... | 06/12/2001 |
| 6193950 | Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuab... | 02/27/2001 |
| 6166071 | Zinc amino acid chelates having ligands comprised of glycine and a sulfur-containing amino acids A zinc amino acid chelate formulation is disclosed comprising zinc ions being chelated by an amino acid ligand mixture comprising glycine and a sulfur-containing amino acid wherein the ligand to zinc molar ratio is from about 1:1 to 2:1 and wherein the gl... | 12/26/2000 |
| 6114379 | Bioavailable chelates of creatine and essential metals A chelate comprised of creatine bonded to an essential mineral selected from the group consisting of Mg, Ca, Cu, Zn, Fe, Cr, Co, Mo, Se and Mn to form a heterocyclic ring. Preferably, the metal is Mg, but Ca, Zn, Fe, Cr and Mn are also preferred. The crea... | 09/05/2000 |
| 6099824 | Benzyloxy derivatives of DTPA for MRI Compounds which can chelate paramagnetic bi- and trivalent metal ions, their chelates with said metal ions and their use as contrast agents in magnetic resonance imaging (MRI), the compounds having formula (I) ##STR1## wherein R is a --(CH2 | 08/08/2000 |
| 6060040 | Cross-linked polymeric compositions for increasing the MRI contrast in visualising the digestive tract of patients The invention provides, as contrast signal generators in MR imaging of the digestive tract, paramagnetic metal chelates of novel acrylic compounds of formula C(R1 R2).dbd.CR3 --CO--Z--A (1) and/or C(R1 R2 | 05/09/2000 |
| 6054117 | Cascade polymer bound complexing compounds, their complexes and conjugates, process for their production, and pharmaceutical agents containing them Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuab... | 04/25/2000 |
| 6045776 | Process for the production of metal-complex carboxylic acid amides The invention relates to a process for the production of metal-complex carboxylic acid amides, characterized in that a metal-complex carboxylic acid mixture that consists of the metal-complex carboxylic acid and at least one solubilizing substance in dime... | 04/04/2000 |
| 5962717 | Plant micronutrient chelating surfactant compounds Plant micronutrient compounds comprising N-acyl ED3A or salts thereof. The N-acyl ED3A derivatives chelate various trace metals, including iron, copper, zinc, manganese, cobalt and nickel.... | 10/05/1999 |
| 5958372 | Low viscosity chelating polymers for diagnostic imaging Disclosed are linear and cross-linked polymers suitable for use as a contrast agent for magnetic resonance imaging containing units comprising the residue of a poly(amine) moiety linked to a chelating agent and to one or more pendant (poly)alkylene oxides... | 09/28/1999 |
| 5914097 | Amino-acyl-type and catecholamine-type contrast agents for MRI The present invention relates to the preparation of amino-acyl-type and catecholamine-type compounds having multiple carboxylic acid functional groups. Paramagnetic metal (II) or (III) ion chelate complexes are formed using these compounds for use as intr... | 06/22/1999 |
| 5914095 | Polychelants containg amide bonds There are provided polychelants and their metal chelates which are useful in diagnostic imaging and in radiotherapy and which comprise a plurality of macrocyclic chelant moieties, e.g. DOTA residues, conjugated to a dendritic polyamine backbone molecule, ... | 06/22/1999 |
| 5885548 | Multiply substituted DTPA derivatives and their metal complexes, and their metal complexes, pharmaceutical agents that contain these complexes, their use in diagnosis and therapy, as well as process for the production of pharmaceutical agents The invention relates to new, multiply substituted diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents that contain these compounds, thei... | 03/23/1999 |
| 5859214 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production Compounds of general formula I ##STR1## wherein Z1, Z2, X, R2 and R3 are as herein defined, are valuable pharmaceutical agents. In particular, the compounds are useful as contrast agents in NMR diagnosis.... | 01/12/1999 |
| 5808013 | Process for the preparation of N-alkyl substituted metal carbamate solutions and their use Process for the preparation of N-alkyl substituted metal carbamate solutions characterized in that a water solution of the salt of the metal of which the corresponding carbamate is to be obtained, is reacted with an organic solution, basically consisting ... | 09/15/1998 |
| 5804164 | Water-soluble lipophilic contrast agents The present invention relates to water-soluble, lipophilic contrast-enhancing agents, pharmaceutical compositions thereof and methods for diagnostic analysis, particularly NMR or MRI analysis using these contrast-enhancing agents. The water-soluble, lipop... | 09/08/1998 |
| 5804163 | Contrast agents for magnetic resonance imaging aminosaccharide A contrast enhancing agent for magnetic resonance images having a chelating agent, which can be bound to metals having at least one unpaired electron. Examples of such chelating agents include 3,6,9-tris(carboxymethyl)-1, 11-bis(dimethylamine)-3,6,9-triaz... | 09/08/1998 |
| 5798092 | Derivatized DTPA complexes pharmaceutical agents containing these compounds, their use, and processes for their production Compounds of general Formula I ##STR1## wherein Z1 and Z2 in each case independently mean the residue --(CH2)m --(C6 H4)q --(O)k --(CH2)n --(C | 08/25/1998 |
| 5789610 | Adhesion-promoting agents incorporating polyvalent cations Materials and methods for preparing the surface of dentin, enamel, or other natural or industrial substrates containing or capable of binding metallic ions, for adhesion of composite materials or resins, are disclosed. Preferably, the substrate is treated... | 08/04/1998 |
| 5762910 | Liposoluble compounds useful as magnetic resonance imaging agents Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspending agents or other ... | 06/09/1998 |
| 5759226 | Neutral metal alkanoate micronutrient solutions and method of manufacturing same A substantially neutral metal alkanoate solution suitable for application of the constituent micronutrient metal to agricultural crops or acreage where such crops are to be grown, is disclosed. Alkanoates having from 2 to 6 carbon atoms are preferred, wit... | 06/02/1998 |
