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| Number | Title | Issue Date |
| 7119218 | Low melting point tin salt of carboxylic acid and method for producing the same The present invention provides a low melting point tin salt of aliphatic monocarboxylic acid obtained by a process comprising, reacting an aliphatic monocarboxylic acid having 4 to 30 carbon atoms or its salt and an inorganic tin compound so as to prepare a tin salt... | 10/10/2006 |
| 6984745 | Environmentally benign lead zirconate titanate ceramic precursor materials The synthesis, processing and test of improved lead zirconate titanate (PZT) precursor materials useful for making bulk, thick films and thin films of PZT are provided. PZT is an oxide ceramic extensively used for its piezoelectric properties. A variety of devices m... | 01/10/2006 |
| 6849668 | Organo-silicon compounds and their use as photoinitiators A multi-functional photoinitiator of formula (I) R1m—Q—(A1—PI)n (I) wherein Q is a heteroatom selected from Si, Ti, Zr and Sn or any two independently selected suc... | 02/01/2005 |
| 6703518 | Fluoride-releasing compositions Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials or other dental materials, to produce materials with high fluoride release rates, and high fluoride recharge capabili... | 03/09/2004 |
| 6686489 | Metal organic precursors for transparent metal oxide thin films and method of making same A liquid precursor for forming a transparent metal oxide thin film comprises a first organic precursor compound. In one embodiment, the liquid precursor is for making a conductive thin film. In this embodiment, the liquid precursor contains a first metal ... | 02/03/2004 |
| 6541514 | Process for the manufacture of 117Sn diethylenetriaminepentaacetic acids Novel methods are provided for the manufacture of 117m Sn(Sn4+) DTPA. The method allows the use of DTPA, a toxic chelating agent, in an approximately 1:1 ratio to 117m Sn(Sn4+) via either aqueous conditions, or ... | 04/01/2003 |
| 6376691 | Metal organic precursors for transparent metal oxide thin films and method of making same A liquid precursor for forming a transparent metal oxide thin film comprises a first organic precursor compound. In one embodiment, the liquid precursor is for making a conductive thin film. In this embodiment, the liquid precursor contains a first metal ... | 04/23/2002 |
| 6303808 | Direct synthesis of tin (II) carboxylates and tin(IV) carboxylates from elemental tin or tin oxides A process for making a product containing tin (II) carboxylates of the formula (RCOO)2-n (OOCR')n, where each R, which may be the same or different, is hydrogen or a C1 -C40 hydrocarbyl group, each R', which may... | 10/16/2001 |
| 6193950 | Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuab... | 02/27/2001 |
| 6099824 | Benzyloxy derivatives of DTPA for MRI Compounds which can chelate paramagnetic bi- and trivalent metal ions, their chelates with said metal ions and their use as contrast agents in magnetic resonance imaging (MRI), the compounds having formula (I) ##STR1## wherein R is a --(CH2 | 08/08/2000 |
| 6060040 | Cross-linked polymeric compositions for increasing the MRI contrast in visualising the digestive tract of patients The invention provides, as contrast signal generators in MR imaging of the digestive tract, paramagnetic metal chelates of novel acrylic compounds of formula C(R1 R2).dbd.CR3 --CO--Z--A (1) and/or C(R1 R2 | 05/09/2000 |
| 6054117 | Cascade polymer bound complexing compounds, their complexes and conjugates, process for their production, and pharmaceutical agents containing them Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuab... | 04/25/2000 |
| 6054600 | Non-toxic solvent soluble group IV and V metal acid salt complexes using polyether acid anhydrides Novel metal acid salt complexes are provided comprising (1) a metal selected from Group IV and Group V metals and (2) a polyether acid, along with a process for making the salt complexes. The process comprises: (a) preparing a polyether acid anhydride fro... | 04/25/2000 |
| 6045776 | Process for the production of metal-complex carboxylic acid amides The invention relates to a process for the production of metal-complex carboxylic acid amides, characterized in that a metal-complex carboxylic acid mixture that consists of the metal-complex carboxylic acid and at least one solubilizing substance in dime... | 04/04/2000 |
| 5958372 | Low viscosity chelating polymers for diagnostic imaging Disclosed are linear and cross-linked polymers suitable for use as a contrast agent for magnetic resonance imaging containing units comprising the residue of a poly(amine) moiety linked to a chelating agent and to one or more pendant (poly)alkylene oxides... | 09/28/1999 |
| 5919964 | Method for the preparation of pure carboxyethyl germanium sesquioxide This invention provides a method for synthesizing pure carboxyethyl germanium sesquioxide that does not include any toxic impurities, such as germanium dioxide or metallic germanium. Neither of these toxic compounds is used as a starting material. The met... | 07/06/1999 |
| 5914095 | Polychelants containg amide bonds There are provided polychelants and their metal chelates which are useful in diagnostic imaging and in radiotherapy and which comprise a plurality of macrocyclic chelant moieties, e.g. DOTA residues, conjugated to a dendritic polyamine backbone molecule, ... | 06/22/1999 |
| 5885548 | Multiply substituted DTPA derivatives and their metal complexes, and their metal complexes, pharmaceutical agents that contain these complexes, their use in diagnosis and therapy, as well as process for the production of pharmaceutical agents The invention relates to new, multiply substituted diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents that contain these compounds, thei... | 03/23/1999 |
| 5804163 | Contrast agents for magnetic resonance imaging aminosaccharide A contrast enhancing agent for magnetic resonance images having a chelating agent, which can be bound to metals having at least one unpaired electron. Examples of such chelating agents include 3,6,9-tris(carboxymethyl)-1, 11-bis(dimethylamine)-3,6,9-triaz... | 09/08/1998 |
| 5804164 | Water-soluble lipophilic contrast agents The present invention relates to water-soluble, lipophilic contrast-enhancing agents, pharmaceutical compositions thereof and methods for diagnostic analysis, particularly NMR or MRI analysis using these contrast-enhancing agents. The water-soluble, lipop... | 09/08/1998 |
| 5798092 | Derivatized DTPA complexes pharmaceutical agents containing these compounds, their use, and processes for their production Compounds of general Formula I ##STR1## wherein Z1 and Z2 in each case independently mean the residue --(CH2)m --(C6 H4)q --(O)k --(CH2)n --(C | 08/25/1998 |
| 5762910 | Liposoluble compounds useful as magnetic resonance imaging agents Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspending agents or other ... | 06/09/1998 |
| 5756069 | Amphipathic polychelating compounds and method of use An amphipathic polychelating compound including a hydrophilic polymeric moiety having a main backbone and a plurality of reactive side groups, a lipid-soluble anchor linked to the N terminal of the polymeric moiety, and a plurality of chelating agents lin... | 05/26/1998 |
| 5746995 | DTPA derivatives substituted in a novel way, their metal complexes, and their use in diagnosis and therapy The invention relates to new diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents that contain these compounds and their use as contrast m... | 05/05/1998 |
| 5730956 | DTPA di-alkyl monoamides for x-ray and MRI The invention relates to diethylenetriaminepentaacetic acid monoamide derivatives, their complexes and complex salts, containing gadolinium, dysprosium, iron or manganese, pharmaceutical agents containing these compounds, their use as contrast media and p... | 03/24/1998 |
| 5703259 | Method for the preparation of pure carboxyethyl germanium sesquioxide A synthetic method for generating pure carboxyethyl germanium sesquioxide in the absence of toxic impurities. In the method germanium dioxide and metallic germanium are not used as starting materials. The method involves steps which ensure (a) absence of ... | 12/30/1997 |
| 5693309 | Substituted complexing agents, complexes, and complex salts, processes for their production, and pharmaceuticals containing same 1. Compounds of general Formula I ##STR1## wherein n and m in each case mean the numbers 0, 1, 2, 3 and 4, X stands for a hydrogen atom and/or a metal ion equivalent of an element of atomic numbers 21-29, 31, 32, 37-39, 42-44, 49 or 57-83, R1 a... | 12/02/1997 |
| 5681544 | Polymer-bonded complexing agents, their complexes and conjugates, processes for their production and pharmaceutical agents containing them Polymers comprising a ligand containing a carboxylic acid group, optionally at least one ion of an element of the atomic numbers 21-29, 42, 44 or 57-83 as well as optionally cations of inorganic and/or organic bases, amino acids or amino acid amides are v... | 10/28/1997 |
| 5672335 | Use of metal complexes as liver and gallbladder X-ray diagnostic agents Metal complexes containing a metal of atomic numbers 39-42, 44-51 or 56-83 and a complexing agent can be used for the production of contrast media for use in the contrast-enhanced computer tomography of the liver and the biliary tracts.... | 09/30/1997 |
| 5571498 | Emulsions of paramagnetic contrast agents for magnetic resonance imaging (MRI). Emulsions of paramagnetic contrast agents, and processes of making and using them are disclosed. The emulsions contain water, a dispersed oil phase and a complex of a paramagnetic metal ion and an organic chelator having a C10 -C30 u... | 11/05/1996 |
| 5559147 | Aromatic fluorine-containing organotin compounds and anti-tumour composition The invention relates to novel aromatic fluorine-containing organotin compounds of the formula {(F5 C6 RCO2 SnBu2)2 O}2 and {(F5 C6 RCO2)2 SnBu2 | 09/24/1996 |
| 5554357 | Magnetic resonance imaging agents containing hydrazide moieties Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with hydrazide derivatives of polyaminocarboxylic acid chelating agents. These novel imaging agents are characterized by excellent NMR image-contrasting properties and by high... | 09/10/1996 |
| 5550266 | Method for the preparation of pure carboxyethyl germanium sesquioxide A synthetic method for generating pure carboxyethyl germanium sesquioxide in the absence of toxic impurities. In the method germanium dioxide and metallic germanium are not used as starting materials. The method involves steps which ensure (a) full reacti... | 08/27/1996 |
| 5494656 | Second sphere complexes as relaxation agents for image enhancement in magnetic resonance imaging A second sphere contrast enhancing agent for magnetic resonance imaging comprises a paramagnetic metal ion having catecholate ligands coordinated thereto and having water molecules hydrogen bonded to the catecholate ligands.... | 02/27/1996 |
| 5482700 | Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast 1. Compounds of general Formula I ##STR1## wherein n and m in each case mean the numbers 0, 1, 2, 3 and 4, X stands for a hydrogen atom and/or a metal ion equivalent of an element of atomic numbers 21-29, 31, 32, 37-39, 42-44, 49 or 57-83, R1 a... | 01/09/1996 |
| 5466439 | Polymeric contrast enhancing agents for magnetic resonance images A polymeric contrast enhancing agent for magnetic resonance images having a chelating agent, which can be bound to metal ions having at least one unpaired electron, such as gadolinium. Examples of such chelating agents include DTPA-ethylenediamide-methacr... | 11/14/1995 |
| 5426202 | Alkyl tin compounds, their synthesis and electrically conductive and IR-reflecting layers The invention relates to compounds of the general formula SnR1a R2b R3c, in which R1 is an alkyl group with 1 to 4 carbon atoms, R2 is an acetate group, R3 is a ... | 06/20/1995 |
| 5386046 | Method for the preparation of pure carboxyethyl germanium sesquioxide A synthetic method for generating pure carboxyethyl germanium sesquioxide in the absence of toxic impurities. In the method germanium dioxide and metallic germanium are not used as starting materials. The method involves the production of pure crystals of... | 01/31/1995 |
| 5308687 | Fiber element containing tin oxide heteropolycondensates with enhanced electrical conductivity Metal oxide heteropolycondensates of tin and boron, particularly heteropolycondensates of this type wherein the major amount of the metal oxide is tin oxide, and a minor amount is boron oxide. The quantity of boron oxide is sufficient to enhance the condu... | 05/03/1994 |
| 5081271 | Novel benzoic acid derivatives and process for preparing the same Benzoic acid derivatives represented by the formula (I): ##STR1## wherein R1 represents hydrogen or lower-alkyl, R2 and R4 represent hydrogen, trimethylsilyl, or trimethylgermyl, R3 represents hydrogen, low... | 01/14/1992 |
