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| Number | Title | Issue Date |
| 8101785 | Method for producing fatty acid alkanol amides The invention relates to a method for producing fatty acid alkanol amides by reacting at least one amine that contains at least one primary or secondary amino group and at least one hydroxyl group with at least one fatty acid to form an ammonium salt, said ammonium ... | 01/24/2012 |
| 7683193 | Benzo lipoxin analogues Benzolipoxin analogs, methods of their preparation and pharmaceutical compositions containing the compounds are provided. The compounds and compositions are useful in methods for treatment of various diseases, including, inflammation, autoimmune disease and abnormal... | 03/23/2010 |
| 7589220 | Inhibitors of the anandamide transporter Disclosed are compounds that are anandamide transport inhibitors and their pharmacological use. ... | 09/15/2009 |
| 7378444 | Analogues of lipid mediators derived from omega-3 PUFAs and methods of use The present invention is directed to compounds that are analogues of lipid mediators derived from a fish oil-derived fatty acid, eicosapentaenoic acid [C20:5 ω-3; EPA], but with a longer tissue half-life and enhanced bioactivity. These analogues may be used to trea... | 05/27/2008 |
| 7253295 | Chloride channel opener Disclosed is a novel use of a prostaglandin compound as a chloride channel opener. According to the instant invention, chloride channels in a mammalian subject can be opened by a prostaglandin compound to facilitate chloride ion transportation. ... | 08/07/2007 |
| 7247701 | Amino amides, peptides and peptidomimetics Synthetic methods and compounds involving amino amides, peptides and peptidomimetics. Amino amide derivatives are prepared via the one-step three-component reaction of a glyoxamide, an amine, and an organoboron derivative. Conversion of the product to another glyoxa... | 07/24/2007 |
| 7161016 | Cannabimimetic lipid amides as useful medications Novel analogs of arachidonylethanolamide are presented which have higher affinities for the cannabinoid CB1 and/or CB2 receptor sites. Further, most of the analogs exhibit greater metabolic stability than arachidonylethanolamide. The improved receptor affinity and s... | 01/09/2007 |
| 6949664 | Trihydroxy polyunsaturated eicosanoids The invention features methods for the preparation of naturally occurring trihydroxy polyunsaturated eicosanoids and their structural analogs. The invention further provides new derivatives of trihydroxy polyunsaturated eicosanoids that can be prepared according to ... | 09/27/2005 |
| 6946542 | Amino amides, peptides and peptidomimetics Synthetic methods and compounds involving amino amides, peptides and peptidomimetics. Amino amide derivatives are prepared via the one-step three-component reaction of a glyoxamide, an amine, and an organoboron derivative. Conversion of the product to another glyoxa... | 09/20/2005 |
| 6927294 | Nitrogen-containing heterocycles Functionalized nitrogen heterocyclic compounds, including benzodiazepines and azasugars, and synthetic methods for preparing such compounds. Nitrogen-containing heterocycles are prepared by reacting amino-carbonyl compounds that contain an amine moiety connected via... | 08/09/2005 |
| 6835846 | Aliphatic compounds, process for their preparation and their usage The present invention provides an aliphatic compound represented by the following formula (I) or pharmacologically acceptable salts thereof: where n denotes an integer of 1 to 11, and 1 denotes... | 12/28/2004 |
| 6803385 | Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders Hydroxyeicosatetraenoic acid esters and methods of their use in treating dry eye disorders are disclosed. ... | 10/12/2004 |
| 6800770 | Anti-spasticity of an eicosanoid analog The invention compounds and methods for the treatment of motor disorders. In particular, the invention provides eicosanoid analogs which are effective in ameliorating motor disorders such as spasticity caused by multiple sclerosis (MS). ... | 10/05/2004 |
| 6693208 | Compounds and compositions for delivering active agents Amino acid derivative as carrier compounds and compositions which are useful in the delivery of active agents are provided. The active agents can be a peptide, mucopolysaccharide, carbohydrate, or lipid. Methods of administration, including oral administr... | 02/17/2004 |
| 6552084 | Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders are disclosed.... | 04/22/2003 |
| 6524353 | Method of enhancing the low temperature solution properties of a gasoline friction modifier A fuel additive composition composed of the reaction product of (a) mixed fatty acid esters; (b) a mono or di-(hydroxy alkyl amine) or mixtures thereof; and (c) a low temperature property enhancing effective amount of a low molecular weight ester; wherein... | 02/25/2003 |
| 6521662 | Ceramide-like compounds having antioxidant property and a method for preparation thereof, and a cosmetic composition containing the same A ceramide-like compound having properties of the natural ceramides are represented by the following formula (I), and a method for producing the same , and a cosmetic composition containing the same as an active ingredient: ##STR1##... | 02/18/2003 |
| 6399798 | Method of preparing alkylated salicylamides The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide (hereinafter referred to as a "protected/activated salicylamide"). The method comprises the steps of (a) alkylating the protected/... | 06/04/2002 |
| 6369248 | Fragrance precursor compounds Compounds having formula (I) in which n is 1, 2 or 3 and R1 to R6 represent, independently, branched or unbranched, substituted or unsubstituted alkyl-, alkenyl-, alkinyl-, cycloalkyl-, cycloalkenyl- or aromatic-radicals or hydrogen ... | 04/09/2002 |
| 6326499 | Omega chain modified 15-hydroxyeicosatetraenoic acid derivatives and methods of their use for the treatment of dry eye Omega chain modified 15-HETE derivatives and methods of their use for treating dry eye are disclosed.... | 12/04/2001 |
| 6320064 | Fatty acid derivatives and their use as surfactants in detergents and cleaners Fatty acid derivatives based on epoxidized unsaturated fatty acid esters or triglycerides and reacted with amines such as hydroxy- and/or amino-substituted hydrophilic amines or amino acids and/or with alkanols or with water on the epoxy group and/or the ... | 11/20/2001 |
| 6320062 | 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders 15-HETE derivatives with enhanced metabolic stability and methods of their use for treating dry eye are disclosed.... | 11/20/2001 |
| 6204238 | Fatty acid derivatives and their use as surfactants in detergents and cleaners Fatty acid derivatives based on epoxidized unsaturated fatty acid esters or triglycerides and reacted with amines such as hydroxy- and/or amino-substituted hydrophilic amines or amino acids and/or with alkanols or with water on the epoxy group and/or the ... | 03/20/2001 |
| 6060612 | Ceramide-like compounds and a method for preparation thereof, and a cosmetic composition containing the same Disclosed herein is a ceramide-like compound having properties of the natural ceramides, and a method for producing the same, and a cosmetic composition containing the same as a active ingredient.... | 05/09/2000 |
| 6054483 | Plant volatile elicitor from insects The invention relates to fatty acids conjugated to amino acids and their derivatives that elicit the production and/or release of plant volatiles compounds which attract and/or retain beneficial insects and deter herbivorous insect feeding. These conjugat... | 04/25/2000 |
| 6020489 | Cytoprotective fatty moiety compounds Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA2 and preventing oxidation. In particular, each compound has at leas... | 02/01/2000 |
| 5997610 | Amphiphilic compounds with at least two hydrophilic and at least two hydrophobic groups based on dicarboxylic acid diamides The invention concerns amphiphilic compounds of general formula (I) ##STR1## with at least two hydrophilic and at least two hydrophobic groups based on diacarboxylic acid diamides. The amphiphilic compounds according to the invention are mostly surfa... | 12/07/1999 |
| 5955452 | Covalent lipid-phosphono-carboxylic acid conjugates and application thereof as antiviral medicaments The present invention concerns new lipid derivatives of phosphonocarboxylic acids of the general formula I, ##STR1## in which the meaning of the symbols is elucidated in the description, tautomers thereof and their physiologically tolerated salts of ... | 09/21/1999 |
| 5917067 | Process for producing an omega-functionalized aliphatic carboxylic acid and intermediate products of said process, including 2-oxepanone-7-substituted products A process for producing an omega-functionalized aliphatic carboxylic acid starting from cyclohexanone and omega-functionalized -olefins or acrylic esters. The process comprises an addition step, an oxidation step, an isomerization step, and one or ... | 06/29/1999 |
| 5861520 | Glycolipid analogs The present invention provides a compound which is a glycolipid analog having a novel structure represented by the formula (1): ##STR1## wherein Z represents an imino group, an oxygen atom or a sulfur atom; m is an integer of from 3 to 12; and n is a... | 01/19/1999 |
| 5855630 | Fuel compositions Multiple amide polyether alcohol compounds of the formula: ##STR1## wherein R1 and R2 are each independently selected from the group consisting of hydrocarbyl of 2 to 100 carbon atoms and substituted hydrocarbyl of 2 to 100 carb... | 01/05/1999 |
| 5856537 | Inhibitors of oleamide hydrolase Inhibitors of oleamide hydrolase, responsible for the hydrolysis of an endogenous sleep-inducing lipid (1, cis-9-octadecenamide) were designed and synthesized. The most potent inhibitors possess an electrophilic carbonyl group capable of reversibly formin... | 01/05/1999 |
| 5840940 | Linoleoylamide based ceramide derivative and its use in cosmetic preparations for the treatment of dry skin The present invention discloses a novel ceramide 3 derivative which is N-linoleoylphytosphingosine (Ceramide IIIA). In addition, a method for preparing this compound is described. The solubility of this diunsaturated ceramide IIIA is much higher than the ... | 11/24/1998 |
| 5792794 | Retinoylamide based derivatives of sphingoid bases The present invention relates to active derivatives of sphingoid bases. Specifically, the invention relates to retinoylamide based derivatives of sphingoid bases. The present invention describes a method for obtaining these compounds. The invention also r... | 08/11/1998 |
| 5786387 | Lipid double-chain derivative containing polyoxyethylene A compound represented by the formula (I) is disclosed. The compound of the formula (I) is useful as a fine particle drug carrier. When used as the fine particle drug carrier, the compound efficiently avoids a reticuloendothelial system and has a long cir... | 07/28/1998 |
| 5770751 | Meadowfoam sulfosuccinates The present invention deals with the certain novel meadowfoam derived sulfosuccinates. These materials are useful as cosmetic ingredients as additives to shampoo systems where outstanding liquidity, resistance to oxidation, and minimal odor variation are ... | 06/23/1998 |
| 5753707 | Amide derivatives and their use in cosmetic composition An amide derivative represented by the following formula (1): ##STR1## wherein R1 represents a C1-40 hydrocarbon; R2 represents a C1-6 alkylene; R3 represents H, OH or alkoxyl; R4 repr... | 05/19/1998 |
| 5741916 | Meadowfoam alkanolamides The present invention deals with the certain novel alkanolamides which are prepared by the reaction of an alkanolamie and meadowfoam fatty, methyl ester or triglyceride. These materials are useful as cosmetic ingredients as additives to shampoo systems wh... | 04/21/1998 |
| 5728852 | Method for producing monohydroxyalkylamides A method for producing a monoalkanol amide comprising the steps of (a) treating an entire amount of fatty acid with a monoalkanol amine in an amount of 0.7 to 0.95 times by mole of the amount of the fatty acid and more than 70% and not more than 90% by we... | 03/17/1998 |
| 5712414 | Hydroxycarboxylic acid anilides The present invention relates to a process for the preparation of hydroxycarboxylic acid amides of the general formula (1): ##STR1## in which R1 and R2 are identical or different and are hydrogen, halogen, cyano, a linear or bra... | 01/27/1998 |
