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| Number | Title | Issue Date |
| 7569711 | Enone cancer therapeutics Described herein are new enone derivatives and conjugates. Additionally, methods for synthesizing these new enones are also disclosed. These compounds can be employed in cancer therapy. ... | 08/04/2009 |
| 7396946 | Compound for treatment of external secretion disorders Disclosed is a method for treatment of external secretion disorders, which comprises administering a fatty 5 acid derivative to a subject in need of said treatment. The method of the present invention is useful for treatment of at least one condition selected from h... | 07/08/2008 |
| 7129272 | Apoptosis inhibitor Disclosed is a method for treatment of a subject having a disease or condition associated with apoptosis, which comprises administering to the subject an effective amount of a 15-keto-prostaglandin compound represented by the following formula (I): | 10/31/2006 |
| 6083501 | Drug for prevention and therapy of diseases caused by fibrinoid formation or thrombus formation in the lung and model animals of the diseases A drug for prevention and therapy of diseases caused by fibrinoid formation or thrombus formation, as well as a model animal of fibrinoid formation or thrombus formation in the lung is disclosed. The drug for preventing and treating diseases caused by fib... | 07/04/2000 |
| 5990329 | Retinoids Compounds of the formula: ##STR1## wherein R2 and X are as described, are disclosed. The compounds are useful for treating dermatological disorders which are accompanied by epithelial lesions, e.g., acne and psoriasis, as well as malignant... | 11/23/1999 |
| 5292915 | Compounds containing carbonate groups and carbonyl groups and the preparation and use thereof The invention relates to compounds containing carbonate groups and carbonyl groups and having the general formula ##STR1## in which R stands for a C1 -C4 -alkyl radical, an aryl radical, or a radical R1, where R1... | 03/08/1994 |
| 5212324 | Treatment of cataract with 15-keto-prostaglandin compounds A compound for treatment of a cataract which is a 15-ketoprostaglandin compound.... | 05/18/1993 |
| 5124083 | 3-substituted and 3,3-disubstituted 4-oxoretinoic acids and their esters There are disclosed 3-substituted and 3,3-disubstituted all-trans-4-oxoretinoic acids and 3-substituted and 3,3-disubstituted 13-cis-4-oxoretinoic acids and their lower alkyl esters.... | 06/23/1992 |
| 4429148 | 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners This disclosure describes novel 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.... | 01/31/1984 |
| 4404393 | 15-Deoxy-16-hydroxy-16-(1'fluorovinyl) prostaglandins and derivatives 15-Deoxy-16-(halovinyl)-16-hydroxy prostaglandins have been prepared.... | 09/13/1983 |
| 4403100 | (11R)-11-Deoxy-11-alkyl-6-oxo-prostaglandins The present invention provides novel (11R)-11-deoxy-11-alkyl-6-oxo-prostaglandins which are useful for curing and preventing duodenal ulcers and for preventing or treating gastrointestinal cell damage caused by the use of other pharmacological agents... | 09/06/1983 |
| 4338252 | 1-Descarboxy-1-ketoester (ketoacid)-prostaglandins This disclosure describes certain 11-hydroxy and 11-deoxy-1-ketocarboxylic acid prostanoic acids and derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents or intermediates.... | 07/06/1982 |
| 4328359 | 15-Deoxy-16-substituted-19-chloro-20-nor-prostane derivatives of the E and F series The invention disclosed herein relates to pharmacologically active prostaglandin derivatives of the E and F series wherein C-16 is substituted with hydrogen, methyl, vinyl or ethynyl and C-19 substituted with chloro and the ଲ-chain consists of 7 car... | 05/04/1982 |
| 4322546 | 15-Deoxy-16-hydroxy-16-allenyl prostane derivatives of the E and F series This invention disclosed herein relates to pharmacologically active 15-deoxy-16-hydroxy prostaglandin derivatives of the E and F series wherein C16 is substituted with allenyl. These compounds are active as hypotensives, antisecretory, bronchodilati... | 03/30/1982 |
| 4303796 | 16-Phenoxy prostaglandin F2 analogs Prostaglandin-type compounds with a phenoxy or substituted-phenoxy substituent at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of pl... | 12/01/1981 |
| 4298754 | 15-Deoxy-16-hydroxy-16-(1'fluorovinyl) prostaglandins and derivatives 15-Deoxy-16-hydroxy-16-(1 halovinyl) prostaglandins have been prepared.... | 11/03/1981 |
| 4296248 | 13,14-Dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE1 compounds The present invention provides novel 13,14-dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 10/20/1981 |
| 4294982 | 13,14-Didehydro-11-deoxy-19-oxo-PGE1 compounds The present invention provides novel 13,14-didehydro-11-deoxy-19-oxo-PGE1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 10/13/1981 |
| 4294979 | 13,14-Dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE2 compounds The present invention provides novel 13,14-dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 10/13/1981 |
| 4293708 | 13,14-Didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE1 compounds The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 10/06/1981 |
| 4292443 | 13,14-Didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE2 compounds The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGE2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 09/29/1981 |
| 4289902 | 13,14-Dihydro-11-deoxy-19-oxo-PGE1 compounds The present invention provides novel 13,14-dihydro-11-deoxy-19-oxo-PGE1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 09/15/1981 |
| 4289900 | 13,14-Didehydro-11-deoxy-19-oxo-PGE2 compounds The present invention provides novel 13,14-didehydro-11-deoxy-19-oxo-PGE2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 09/15/1981 |
| 4284795 | 19,20-Didehydro-PG2 compounds The present invention provides novel 19,20-didehydro-PG2 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.... | 08/18/1981 |
| 4282377 | 13,14-Dihydro-11-deoxy-19-oxo-PGE2 compounds The present invention provides novel 13,14-dihydro-11-deoxy-19-oxo-PGE2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 08/04/1981 |
| 4281163 | 11-Deoxy-11-hydroxymethyl-19-oxo-PGE1 compounds The present invention provides novel 11-deoxy-11-hydroxymethyl-19-oxo-PGE1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 07/28/1981 |
| 4281153 | 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners This disclosure describes novel 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.... | 07/28/1981 |
| 4281156 | 11-Deoxy-11-hydroxymethyl-19-oxo-PGE2 compounds The present invention provides novel 11-Deoxy-11-hydroxymethyl-19-oxo-PGF2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 07/28/1981 |
| 4281160 | 11-Deoxy-19-oxo-PGE1 compounds The present invention provides novel 11-deoxy-19-oxo-PGE1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 07/28/1981 |
| 4278806 | 15-Deoxy-16-substituted-19-chloro-20-nor prostane derivatives of the E and F series The invention disclosed herein relates to pharmacologically active prostaglandin derivatives of the E and F series wherein C-16 is substituted with hydrogen, methyl, vinyl or ethynyl and C-19 substituted with chloro and the ଲ-chain consists of 7 car... | 07/14/1981 |
| 4277616 | 11-Deoxy-19-oxo-PGE2 compounds The present invention provides novel 11-Deoxy-19-oxo-PGE2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.... | 07/07/1981 |
| 4276428 | 19,20-Didehydro-13,14-dihydro-PG1 compounds The present invention provides novel 19,20-didehydro-13,14-dihydro-PG1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.... | 06/30/1981 |
| 4276427 | 19,20-Didehydro-PG1 compounds The present invention provides novel 19,20-didehydro-PG1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.... | 06/30/1981 |
| 4275233 | 19-Hydroxy-19-methyl-13,14-dihydro-PG2 compounds The present invention provides novel 19-hydroxy-19-methyl-13,14-dihydro-PG2 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.... | 06/23/1981 |
| 4275231 | 19-Hydroxy-19-methyl-13,14-dihydro-PG1 compounds The present invention provides novel 19-hydroxy-19-methyl-13,14-dihydro-PG1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.... | 06/23/1981 |
| 4269995 | 19,20-Didehydro-13,14-dihydro-PG2 compounds The present invention provides novel 19,20-didehydro-13,14-dihydro-PG2 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.... | 05/26/1981 |
| 4267361 | 1-Descarboxy-1-ketoester (ketoacid) prostaglandins This disclosure describes certain 11-hydroxy and 11-deoxy-1-ketocarboxylic acid prostanoic acids and derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents or intermediates.... | 05/12/1981 |
| 4260805 | 1-Descarboxy-1-ketoester (ketoacid)-prostaglandins This disclosure describes certain 11-hydroxy and 11-deoxy-1-ketocarboxylic acid prostanoic acids and derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents or intermediates.... | 04/07/1981 |
| 4259514 | 19-Hydroxy-13,14-dihydro-PG2 compounds The present invention provides novel 19-hydroxy-13,14-dihydro-PG2 compounds methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.... | 03/31/1981 |
| 4259250 | 11a-Homo-PG intermediates for preparing 11a-methano TXA2 compounds The present invention provides novel thromboxane analogs and intermediates. Particularly, the present invention provides novel 11a-homo-PG intermediates for preparing 11a-methano TXA2 compounds.... | 03/31/1981 |
