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Class 554/117 - Alicyclic ring in the acid moiety (e.g., prostaglandin analogs, etc.)


Subclass of Class 554 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which contain an alicyclic ring in the acid moiety.
No. of patents: 73
Last issue date: 05/04/2010


1    
NumberTitleIssue Date
7709666Transgenic plants containing altered levels of sterol compounds and tocopherols
Provided are recombinant constructs comprising DNA sequences encoding enzymes effective in altering the biosynthesis and accumulation of sterol compounds and tocopherols in transgenic plants. Also provided are methods of using such constructs to produce transgenic p...
05/04/2010
7396946Compound for treatment of external secretion disorders
Disclosed is a method for treatment of external secretion disorders, which comprises administering a fatty 5 acid derivative to a subject in need of said treatment. The method of the present invention is useful for treatment of at least one condition selected from h...
07/08/2008
7132453Method of using prostacyclin to treat respiratory syncytial virus infections
The present invention discloses methods and a kit for treating a respiratory syncytial virus infection. The method comprises providing an infection modulator, and administering a therapeutically effective amount of the infection modulator, wherein the respiratory sy...
11/07/2006
6972123Polymeric castor polyester quaternary compounds based upon dimer acid
The present invention deals with the certain castor polyesters that give high gloss when applied to the skin. Said ester are the reaction of the hydroxyl group of castor oil with less than one equivalent of a fatty acid then in a subsequently step the remainder of a...
12/06/2005
6953849Process for the isolation of glycolipids
The present invention relates to a process for the isolation of a glycolipid enriched fraction from rice bran oil by subjecting crude rice bran oil to at least two steps of dewaxing/degumming, treating sludge obtained as a byproduct of the second said dewaxing/degum...
10/11/2005
6933289Inhibition of irritating side effects associated with use of a topical ophthalmic medication
This invention relates to a method of reducing an irritating or adverse side effect associated with the topical use of an active ophthalmic drug comprising incorporating an effective amount of a cyclodextrin or cyclodextrin derivative into a formulation to complex t...
08/23/2005
6878522Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2
The present invention relates to the discovery that PDG2 is the nautral ligand for orphan receptor CRTH2, which interaction, it will now immediately be recognized, is important in the development of valuable pharmaceuticals. The present invention is there...
04/12/2005
6713268Methods of identifying ocular hypotensive compounds having reduced hyperpigmentation
Methods to identify agents having ocular hypotensive activity which have reduced or absent ability to stimulate iridial hyperpigmentation are disclosed. The methods reside in part in detecting the ability of a test compound to interact with the FP receptor. ...
03/30/2004
6403817Method for preparing prostaglandin E-type compound
The present invention discloses a method for preparing a prostaglandin E-type compound, in which prostaglandin F-type compound is used as an initiator to generate novel derivative of prostaglandin F-type compound through a silylation reaction, and eventua...
06/11/2002
6239298Fuel lubricity additives
There is disclosed a fuel lubricity additive, made by a two-step process wherein the first step is co-reacting an unsaturated base oil, predominantly from vegetable oil sources, and a compound having a diene structure and a carboxylic acid group, wherein ...
05/29/2001
6083501Drug for prevention and therapy of diseases caused by fibrinoid formation or thrombus formation in the lung and model animals of the diseases
A drug for prevention and therapy of diseases caused by fibrinoid formation or thrombus formation, as well as a model animal of fibrinoid formation or thrombus formation in the lung is disclosed. The drug for preventing and treating diseases caused by fib...
07/04/2000
5990346Prostaglandins and processes for production thereof
A prostaglandin having formula (I), (II), or (III): ##STR1## a process of production thereof, and inhibitors of cell migration caused by chemokines containing (I) or (II) as an active ingredient....
11/23/1999
5750750High viscosity complex alcohol esters
A complex alcohol ester which comprises the reaction product of an add mixture of the following: a polyhydroxyl compound represented by the general formula: R(OH)n wherein R is any aliphatic or cyclo-aliphatic hydrocarbyl group and n is at leas...
05/12/1998
5639899Prostaglandin E1 analogues
Object: To provide novel prostaglandin E1 analogues which have more excellent pharmaceutical effects, longer duration of the effects and less side-effects than the prior art prostaglandin E1 's. Constitution: A PGE1 analogue re...
06/17/1997
5292915Compounds containing carbonate groups and carbonyl groups and the preparation and use thereof
The invention relates to compounds containing carbonate groups and carbonyl groups and having the general formula ##STR1## in which R stands for a C1 -C4 -alkyl radical, an aryl radical, or a radical R1, where R1...
03/08/1994
5212324Treatment of cataract with 15-keto-prostaglandin compounds
A compound for treatment of a cataract which is a 15-ketoprostaglandin compound....
05/18/1993
5053525Oxo-analogs of mevinolin-like antihyper-cholesterolemic agents
Mevinolin-like compounds in which the lactone is opened and the hydroxyl function produced thereby is replaced by an oxo function are potent HMG-CoA reductase inhibitors possessing one less asymmetric center....
10/01/1991
5045586Lubricants for thermoplastic resins
The present invention is directed to branched polyesters derived from the reaction product of hydroxy stearic acid or hydroxy stearic alkoxylate, a guerbet alochol or guerbet alcohol alkoxylate, which product is further reacted with a polycarboxylic acid ...
09/03/1991
4523042Derivatives of alpha-alkyl polyolefinic carboxylic acid useful in the treatment of psoriasis
This invention relates to novel compounds having pharmaceutical activity and having the general structure ##STR1## wherein the Z, R1, R2, R3, R4, n and m are defined within....
06/11/1985
440439315-Deoxy-16-hydroxy-16-(1'fluorovinyl) prostaglandins and derivatives
15-Deoxy-16-(halovinyl)-16-hydroxy prostaglandins have been prepared....
09/13/1983
4363817Enol acylate analogs of E1 and E2 prostaglandins
Disclosed are C-9 enol acylate analogs of E1 and E2 prostaglandins which are variously useful as bronchodilators, gastric anti-secretory agents and cyto-protective agents....
12/14/1982
43496909-Deoxy-9-methylene-6-keto-PGE-type compounds
The present invention provides novel 9-deoxy-9-methylene-6-keto-PGE derivatives which are useful for platelet aggregation inhibition and gastric cyctoprotection....
09/14/1982
430259613,14-Didehydro-11-deoxy-9-deoxy-9-methylene-19-oxo-PGF2 compounds
The present invention provides novel 13,14-didehydro-11-deoxy-9-deoxy-9-methylene-19-oxo-PGF2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
11/24/1981
429625013,14-Dihydro-9-deoxy-9-methylene-19-oxo-PGF1 compounds
The present invention provides novel 13,14-dihydro-9-deoxy-9-methylene-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/20/1981
429624913,14-Dihydro-11-deoxy-9-deoxy-9-methylene-19-oxo-PGE1 compounds
The present invention provides novel 13,14-dihydro-11-deoxy-9-deoxy-9-methylene-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/20/1981
429624713,14-Dihydro-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF.sub. 1
The present invention provides novel 13,14-dihydro-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF.sub .1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/20/1981
429624613,14-Didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF1 compounds
The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/20/1981
429498413,14-Didehydro-11-deo xy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF1 compounds
The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF.s ub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/13/1981
429498313,14-Didehydro-11-deoxy-19-oxo-PGF1 compounds
The present invention provides novel 13,14-didehydro-11-deoxy-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/13/1981
429498113,14-Didehydro-11-deoxy-9-deoxy-9-methylene-19-oxo-PGF1 compounds
The present invention provides novel 13,14-didehydro-11-deoxy-9-deoxy-9-methylene-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/13/1981
429498013,14-Dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF1 compounds
The present invention provides novel 13,14-dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/13/1981
429497813,14-Didehydro-19-oxo-PGF2 compounds
The present invention provides novel 13,14-didehydro-19-oxo-PGF2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/13/1981
429371013,14-Dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF2 compounds
The present invention provides novel 13,14-dihydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications. DESCRIPTION...
10/06/1981
429370913,14-Dihydro-9-deoxy-9-methylene-19-oxo-PGF2 compounds
The present invention provides novel 13,14-dihydro-9-deoxy-9-methylene-19-oxo-PGF2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
10/06/1981
429243813,14-Didehydro-9-deoxy-9-methylene-19-oxo-PGF2 compounds
The present invention provides novel 13,14-didehydro-9-deoxy-9-methylene-19-oxo-PGF2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
09/29/1981
429244113,14-Didehydro-11-deo xy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF2 compounds
The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-9-deoxy-9-methylene-19-oxo-PGF.s ub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
09/29/1981
429244213,14-Didehydro-11-deoxy-19-oxo-PGF2 compounds
The present invention provides novel 13,14-didehydro-11-deoxy-19-oxo-PGF2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
09/29/1981
429244013,14-Didehydro-9-deoxy-9-methylene-19-oxo-PGF1 compounds
The present invention provides novel 13,14-didehydro-9-deoxy-9-methylene-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
09/29/1981
428990113,14-Dihydro-11-deoxy-19-oxo-PGF1 compounds
The present invention provides novel 13,14-dihydro-11-deoxy-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
09/15/1981
428861713,14-Didehydro-19-oxo-PGF1 compounds
The present invention provides novel 13,14-didehydro-19-oxo-PGF1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications....
09/08/1981
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