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| Number | Title | Issue Date |
| 7288672 | Process for preparation of esters of hydroxy tiglic Aldehydes The present invention relates to a process for the preparation of esters of hydroxy tiglic aldehydes which are the key intermediates for Vitamin-A acetate synthesis and various perfumistic products, said process relates to the hydroformylation of biscarboxylic ester... | 10/30/2007 |
| 7253296 | Acylated aminopropanediols and analogues and therapeutic uses thereof The invention relates to novel acylated aminopropanediols and the nitrogen and sulfur analogues thereof, pharmaceutical compositions comprising same, therapeutic uses thereof, in particular for the treatment of cerebral ischemia. The invention also provides a method... | 08/07/2007 |
| 7115728 | Human peroxisome proliferator activated receptor γ The present invention relates to a novel human peroxisome proliferator activated receptor, hPPARγ. hPPARγ differs from the mouse peroxisome proliferator activated receptor γ in the nucleotide sequence and the amino acid sequence. The invention provides isolated, ... | 10/03/2006 |
| 7098025 | Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor This invention relates to the isolation and cloning of the promoter and other control regions of human PPARγ gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the level o... | 08/29/2006 |
| 6924309 | Anti-inflammatory nitro and thia-fatty acids The present invention relates to compounds of the general formula: NO2-A-B wherein A is a saturated or unsaturated hydrocarbon chain of 14-26 carbon atoms and B is (CH2)n(COOH)m in which n is an integer from 0 to 2 and m i... | 08/02/2005 |
| 6696606 | Solid phase synthesis of arylretinamides A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reactin... | 02/24/2004 |
| 6071510 | Modified amino acids and compositions comprising the same for delivering active agents The present invention provides modified amino acids for delivering active agents, and particularly biologically or chemically active agents. The preferred modified amino acids of the present invention include N-acylated or sulfonated amino acids. These mo... | 06/06/2000 |
| 5990165 | Pharmaceutical compounds A pharmaceutical compound of the formula: ##STR1## in which n is 1 or 2, R1 is --CO2 H, R2 is hydrogen or C1-4 alkyl and R3 is hydrogen, C1-10 alkyl, C2-10 alkenyl, optionally ... | 11/23/1999 |
| 5879681 | Compounds and compositions for delivering active agents Carrier compounds, compositions, and dosage unit forms therefor which are useful in the delivery of active agents are provided. The present invention provides a compound having the formula: ##STR1## or a salt thereof, wherein the compound may be used... | 03/09/1999 |
| 5876710 | Compounds and compositions for delivering active agents Carrier compounds, compositions, and dosage unit forms therefor which are useful in the delivery of active agents are provided. The present invention provides a compound having the formula: ##STR1## or a salt thereof, wherein the compound may be used... | 03/02/1999 |
| 5866536 | Compounds and compositions for delivering active agents Carrier compounds, compositions, and dosage unit forms therefor which are useful in the delivery of active agents are provided. The present invention provides a compound having the formula: ##STR1## or a salt thereof, wherein the compound may be used... | 02/02/1999 |
| 5734069 | Biodegradable amidoaminoesters Compounds of the formula R--C(O)O(CH2)1-5 !0-1 --C(O)NH(CH2)2-5 --N(R2)--(CH2)2-5 --OC(O)R1 wherein R and R1 are each C8 -C22 ... | 03/31/1998 |
| 5659049 | Antioxidant, antiphospholipase derivatives of ricinoleic acid Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA2 and preventing oxidation. In particular, each compound has at leas... | 08/19/1997 |
| 5508444 | Cyclic compounds Novel substituted cis-1,2-dihydroxy-cyclohexadiene compounds, useful as intermediates in the production of compounds for use as intermediates in the production of agrochemicals and pharmaceuticals, and a microbial process for the preparation thereof.... | 04/16/1996 |
| 5439937 | Leukotriene B4 antagonists This invention relates to compounds of Formula I and the stereoisomers and pharmaceutically acceptable salts thereof ##STR1## wherein R is alkyl, alkenyl, alkynyl, or cycloalkylalkyl; R1 is alkyl; R2 is hydrogen, alkyl; R6... | 08/08/1995 |
| 5174917 | Compositions containing n-ethyl hydroxamic acid chelants N-ethyl hydroxamic acids, preferably containing at least 10 carbon atoms, useful as metal chelants for use in organic solvent extractant solutions such as kerosene to extract metals from aqueous solutions by forming complexes of the extracted metal with t... | 12/29/1992 |
| 5147868 | Thienamycin renal peptidase inhibitors Novel chemical compounds are provided which selectively inhibit the metabolism of dipeptidase (E.C.3.4.13.11) and therefore are useful in combination with antibacterial products. These chemical compounds are z-2-acylamino-3-monosubstituted propenoates.... | 09/15/1992 |
| 5045338 | Secondary amide esters as low calorie fat mimetics Secondary amide esters of the general formula ##STR1## where A is an organic radical having 2 to 6 carbons, m=1 to 3, n=1 to 3, and each R is, independently, an aliphatic, ether or ester group having 1 or 2 to 29 carbons are edible, preferably partially d... | 09/03/1991 |
| 5019593 | Antifungal fermentation products and compositions thereof A mixture of derivatives of 2-amino-3,4,5,14-tetrahydroxy-6-eicosenoic acid has been isolated from a culture medium after cultivation of microorganisms belonging to the genus Aspergillus. The compounds are useful as antifungal agents.... | 05/28/1991 |
| 4980096 | Photolabile blocked surfactants Surfactants which are blocked against surfactant action (identified herein as "photolabile blocked surfactants") by a photolabile protective or masking group but which, on exposure to actinic radiation, become unblocked are provided. Coating compositions ... | 12/25/1990 |
| 4978395 | Polymeric dispersing agent Polyaddition product the molecule of which is characterized by the presence of one group ##STR1## Method to prepare the above mentioned product and dispersions in polar and non polar diluents which contain the said product in addition with solid ... | 12/18/1990 |
| 4978759 | Process for the stereospecific synthesis of optically pure 4-amino-3-hydroxycarboxylic acid derivatives The process described makes it possible to obtain optically pure 4-amino-3-hydroxycarboxylic acids by means of a series of stereoselective steps. The starting material is an alpha-amino acid in the L or D configuration, with which Meldrum's acid is reacte... | 12/18/1990 |
| 4956123 | Method for manufacture of fluorine-containing aromatic derivatives Fluorine-containing aromatic derivatives are produced by the reaction of di(haloacyl)peroxide represented by the general formula: ##STR1## (wherein X stands for a fluorine, chlorine, or hydrogen atom and n for an integer of the value of 1 to 10) with... | 09/11/1990 |
| 4933367 | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds This invention relates to carboxylic acid derivatives and their use thereof. The compounds are useful in treatment of various diseases such as diabetes, prediabetic conditions, adipositas ailments or atherosclerosis.... | 06/12/1990 |
| 4883901 | Synthesis of 2-(4-aminophenoxy)alkanoic acids and esters and their derivatives A method for synthesizing 2-(4-amidophenoxy)alkanoic acids and esters and 2-(4-aminophenoxy)alkanoic acids and esters by reacting a hydroxyaromatic ketone derivative with a 2-substituted alkanoic acid or ester under basic conditions and thereafter reactin... | 11/28/1989 |
| 4863941 | Glycerol derivatives Glycerol derivatives of the formula ##STR1## wherein one of the residues R1, R2 and R3 is a group U of the formula OY1 or --X1 --CO--(A1)n --Z1, another residue i... | 09/05/1989 |
| 4806280 | Process for the preparation of unsaturated compound -chlorinated with respect to two electron-attracting groups in a ଲ-position Compounds of formula ##STR1## in which n denotes an integer from 1 to 10 and X and Y, which are identical or different, each denote an electron-attracting group, are made by reacting a halogenating agent with a compound of formula ##STR2## ... | 02/21/1989 |
| 4740600 | Photolabile blocked surfactants and compositions containing the same Surfactants which are blocked against surfactant action (identified herein as "photolabile blocked surfactants") by a photolabile protective or masking group but which, on exposure to actinic radiation, become unblocked are provided. Coating compositions ... | 04/26/1988 |
| 4677120 | Topical prodrugs for treatment of acne and skin diseases Esters and amides of 13-cis-retinoic acid are disclosed which are used for the treatment of acne and skin diseases.... | 06/30/1987 |
| 4668703 | γ-allenyl-γ-aminobutyric acids This invention is for γ-allenyl-γ-aminobutyric acid derivatives which are γ-aminobutyric acid transaminase inhibitors.... | 05/26/1987 |
| 4659372 | Biocidal 2-aryl-1,3-cyclohexanedione enol ester compounds 2-Aryl-1,3-cyclohexanedione enol ester compounds exhibit outstanding miticidal, mite ovicidal and herbicidal activity.... | 04/21/1987 |
| 4604407 | Hydroxamates Hydroxamates are provided having the structure ##STR1## wherein R1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, or ##STR2## wherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C1 -C4 ... | 08/05/1986 |
| 4588823 | 9-substituted carbacyclin analogs Novel compounds of the following general formula: ##STR1##... | 05/13/1986 |
| 4570011 | Preparation of cyclobutene substituted aromatic hydrocarbons The invention is a process for the preparation of an aromatic hydrocarbon with a cyclobutene ring fused to the aromatic hydrocarbon which comprises, dissolving an ortho alkyl halomethyl aromatic hydrocarbon in an inert solvent and pyrolyzing the solution ... | 02/11/1986 |
| 4559226 | Self-emulsifying alkoxylate esters Novel self-emulsifying alkoxylate esters are described having a cloud point of less than about 15° C. the structural formula: ##STR1## R1 contains from 2 to 20 carbon atoms and is selected from the group consisting of aliphatic and aromat... | 12/17/1985 |
| 4526723 | Biocidal enol esters of non-ortho substituted 2-aryl-1-3-cycloalkanedione compounds Non-ortho substituted 2-aryl-1,3-cycloalkanedione enol ester compounds exhibit outstanding acaricidal and herbicidal activity.... | 07/02/1985 |
| 4495362 | Process for preparing alkyl nitroacetates A process for preparing alkyl nitroacetates by reacting an alkyl phenyl carbonate with a nitroparaffin in a polar aprotic solvent in the presence of a cyanide ion. The process permits a higher reaction rate, and thus the reaction can be completed even at ... | 01/22/1985 |
| 4477556 | Acidic o-nitroaromatics as photoinhibitors of polymerization in positive working films A photopolymerizable coating composition comprising (1) a nongaseous, ethylenically unsaturated, polymerizable compound, (2) a specified acidic o-nitroaromatic compound, and (3) an organic, radiation-sensitive, free-radical generating system which is useful for mak... | 10/16/1984 |
| 4435575 | Process for preparing carboxylated organic compounds A process is herein described for preparing carboxylated organic compounds (acids, esters, alkaline salts) of formula ##STR1## wherein R is a hydrocarbyl group having up to 11 carbon atoms (an aliphatic, alicyclic, aryl- or heteroarylalkyl group), al... | 03/06/1984 |
| 4422870 | Biocidal 2-aryl-1, 3-cyclohexanedione enol ester compounds 2-Aryl-1, 3-cyclohexanedione enol ester compounds exhibit outstanding miticidal,mite ovicidal and herbicidal activity.... | 12/27/1983 |