"What can be more palpably absurd than the prospect held out of locomotives traveling twice as fast as stagecoaches?"
The Quarterly Review ; March edition, 1825
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| Number | Title | Issue Date |
| 7420071 | Thermally stable surfactants and compositions and methods of use thereof There are provided novel thermally stable surfactants for use with fillers in the preparation of polymer composites and nanocomposites. Typically, surfactants of the invention are urethanes, ureas or esters of thiocarbamic acid having a hydrocarbyl group of from 10 ... | 09/02/2008 |
| 7164034 | Alpha2delta ligands for fibromyalgia and other disorders This invention relates to a method of treating a disorder selected from OCD, agoraphobia, agoraphobia without history of panic disorder, specific phobia, social phobia, PTSD, restless legs syndrome, premenstrual dysphoric disorder, hot flashes, and fibromyalgia by a... | 01/16/2007 |
| 6831186 | Lipoxin A4 analogs This invention is directed to lipoxin A4 analogs of the following formula (I) and (II): wherein R1, R2, R3, R4 and R5 are described herein. These analog... | 12/14/2004 |
| 6700006 | Internally plasticizing and crosslinkable monomers and applications thereof Novel compounds derived from traditional semi- drying and non-drying oils featuring internally plasticizing and crosslinkable properties are disclosed and claimed. Preferred embodiments include acrylate or methacrylate esters of hydroxy long-chain olefini... | 03/02/2004 |
| 6696606 | Solid phase synthesis of arylretinamides A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reactin... | 02/24/2004 |
| 6649780 | Cationic lipids Cationic lipids are provided which are useful in the preparation of liposomes and other lipid vesicle carriers. The lipids of the invention are particularly useful as carriers of nucleic acids and other negatively charged substances, for delivery to cells... | 11/18/2003 |
| 6642398 | Mono-and disubstituted 3-propyl gamma-aminobutyric acids The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I ##STR1## The compounds are useful as therapeutic agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, ... | 11/04/2003 |
| 6600059 | Cytoprotective compounds The present invention provides compositions and methods for protecting cells from injury due to intrinsic membrane lysis, oxidation and/or invasion by destructive agents. Even more particularly, the present invention provides compositions and methods for ... | 07/29/2003 |
| 6503945 | Cationic amphiphiles containing N-hydroxyalkyl group for intracellular delivery of biologically active molecules The present invention provides novel cationic amphiphiles containing novel N-hydroxyalkyl group and therapeutic formulations containing the said amphiphiles that are capable of facilitating transport of biologically active molecules into cells. The said n... | 01/07/2003 |
| 6458837 | Lipophilic diesters of chelating agents The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to the present invention are stable lipophilic diesters compris... | 10/01/2002 |
| 6423855 | Cytoprotective compounds The present invention provides compositions and methods for protecting cells from injury due to intrinsic membrane lysis, oxidation and/or invasion by destructive agents. Even more particularly, the present invention provides compositions and methods for ... | 07/23/2002 |
| 6346516 | Cationic amphiphiles containing N-hydroxyalkyl group for intracellular delivery of biologically active molecules The present invention provides novel cationic amphiphiles containing novel N-hydroxyalkyl group and therapeutic formulations containing the said amphiphiles that are capable of facilitating transport of biologically active molecules into cells. The said n... | 02/12/2002 |
| 6271185 | Water soluble vegetable oil esters for industrial applications Industrial oils containing partial esters of triacylglycerol and triethanolamine or ethoxylated triethanolamine are described, as well as methods for making such oils.... | 08/07/2001 |
| 6239297 | Sphingosine derivatives and medicinal composition The present invention intends to provide a derivative of sphingosine analogue that is able to regulate the functions of sphigolipid, and its pharmaceutical compositions. The present invention is the derivatives of sphingosine analogues represented by the ... | 05/29/2001 |
| 6235916 | Internally plasticizing and crosslinkable monomers and applications thereof Novel compounds derived from traditional semi-drying and non-drying oils featuring internally plasticizing and crosslinkable properties are disclosed and claimed. Preferred embodiments include acrylate or methacrylate esters of hydroxy long-chain olefinic... | 05/22/2001 |
| 6221371 | Pseudoceramides, and dermatologic external preparations containing the same The present invention relates to pseudoceramide derivatives represented by formula(I) or (II): R1 --COCHR2 CONR3 R4 (I) R1 --CH(OH)CHR2 CONR3 R4 (II) wherein, each of R1 | 04/24/2001 |
| 6072063 | Low-melting ester quats Ester quats of the formula (1) below are described: ##STR1## where RCO is an aliphatic acyl radical having 6 to 22 carbon atoms, R1 is a methyl radical, R2 is a C1 -C6 -alkyl radical, R3 is a C | 06/06/2000 |
| 6020489 | Cytoprotective fatty moiety compounds Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA2 and preventing oxidation. In particular, each compound has at leas... | 02/01/2000 |
| 5977391 | (+)- and (-) -8-halogen-6- hydroxy-octanoic acid its salts and esters and process for making The invention relates to (+) and (-)-8-halogen-6-hydroxy-octanoic acid enantiomers wherein the halogen is Cl, Br, or I, and their respective preparatory processes.... | 11/02/1999 |
| 5886201 | Quaternized fatty acid triethanolamine ester salts with improved solubility in water A process for producing quaternized fatty acid triethanolamine ester salts having improved solubility in water, by esterifiying a fatty acid mixture containing a) 40% to 60% by weight of linear fatty acids containing 6 to 22 carbon atoms, and b) 60% to 40... | 03/23/1999 |
| 5880299 | Esterquats The invention relates to new esterquats which are obtained by reacting trialkanolamines with a mixture of fatty acids and dicarboxylic acids and quaternizing the resulting esters in known manner, optionally after alkoxylation. Cationic surfactants are obt... | 03/09/1999 |
| 5869713 | (+)- or (-) -8-halogen-6-hydroxy-octanoic acid, its salts and esters, and process for making The invention relates to (+) and (-)-8-halogen-6-hydroxy-octanoic acid enantiomers wherein the halogen is Cl, Br, or I, and their respective preparatory processes.... | 02/09/1999 |
| 5869715 | Polyfunctional cationic cytofectins For use in transporting biologically active species into and through membrane barriers, a cationic amine compound is utilized that has the general structure: ##STR1## wherein R4 and R5 are a pair of same or different lipoyl ... | 02/09/1999 |
| 5869714 | Salts of omega-3-polyunsaturated fatty acids and pharmaceutical formulations containing them Salts of formula RCOOR'R"2 N+ (CH2)n OH wherein R represents the alkenyl radical of a C20 -C22 omega-3-polyunsaturated acid; R' represents a hydrogen atom or a C1 -C2 ... | 02/09/1999 |
| 5852196 | 12,13,17-trihydroxy-9(z)-octadeoenoic acid and derivatives and microbial isolate for production of the acid A novel compound, 12,13,17-trihydroxy-9(Z)-octadecenoic acid (THOA) was produced from linoleic acid by microbial transformation at 25% yield. The newly isolated microbial strain catalyzing this transformation was identified as Clavibacter sp. ALA2 (Access... | 12/22/1998 |
| 5824812 | Polyfunctional cationic cytofectins, formulations and methods for generating active cytofectin: polynucleotide transfection complexes Amine containing compounds and their use in the generation of cytofectin:polynucleotide complexes for transfection of cells, formulations, counterions, and reaction conditions for maximizing the transfection include using cationic amine compounds that hav... | 10/20/1998 |
| 5705663 | Quaternized triethanolamine difatty acid esters The invention relates to quaternized triethanolamine difatty acid esters prepared from triethanolamine, fatty acid, fatty acid ester and a quaternizing agent and to a process for their preparation and to their use. The quaternized triethanolamine difatty ... | 01/06/1998 |
| 5681915 | Use of polyol derivatives as internal lubricants in the production of molded parts of polyurethane The use of polyol derivatives with at least two alcoholic hydroxy groups and at least one fatty acid residue per molecule obtainable by reacting a starting polyol with a fatty acid or a fatty acid derivative, which can be obtained by using as a starting p... | 10/28/1997 |
| 5670677 | Process for the production of color- and odor-stable quaternized fatty acid triethanolamine ester salts A process for the production of color- and odor-stable quaternized fatty acid triethanolamine ester salts comprising the steps of A) partially or fully esterifying triethanolamine with at least one fatty acid in the presence of hypophosphorous acid; B) adding ... | 09/23/1997 |
| 5659055 | Cytoprotective fatty moiety compounds Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA2 and preventing oxidation. In particular, each compound has at leas... | 08/19/1997 |
| 5610187 | Biodegradable quaternary hair and skin conditioners Disclosed are conditioning compositions for the hair and skin containing compounds of the formula (R1)(R2)N(CHCH2 OC(O)R)2 X- wherein R1 is alkyl containing 1 to 6 carbon atoms, or hydroxy... | 03/11/1997 |
| 5574179 | Concentrated biodegradable quaternary ammonium fabric softener compositions and compouds containing intermediate iodine value unsaturated fatty acid chains The present invention relates to softening compounds; stable, homogeneous, preferably concentrated, aqueous liquid and solid textile treatment compositions; and intermediate compositions and/or processes for making said compositions. The compositions of t... | 11/12/1996 |
| 5525709 | Process for the preparation of ceramides The invention relates to the preparation of ceramides by a two step process involving conversion of a 2-hydroximino-3-oxo-alkanoate into a 2-alkanoylamido-3-oxo-alkanoate intermediate by acylation of the oxime and reduction of the oxime ester group to an ... | 06/11/1996 |
| 5296622 | Quaternized esters Quaternized esters having fabric-softening and hydrophilicizing properties are obtained by reaction of unsaturated fatty acids containing at least 40 mol-% transconfigured double bonds or esters thereof with alkanolamines and subsequent quaternization of ... | 03/22/1994 |
| 5292915 | Compounds containing carbonate groups and carbonyl groups and the preparation and use thereof The invention relates to compounds containing carbonate groups and carbonyl groups and having the general formula ##STR1## in which R stands for a C1 -C4 -alkyl radical, an aryl radical, or a radical R1, where R1... | 03/08/1994 |
| 5266724 | Fluorine-containing compounds A fluorine-containing compound of the formula ##STR1## wherein Rf is a fluoroalkyl ether end group having 5 to 50 carbon atoms, R1 is an alkyl end group or an aliphatic alkenyl end group, R'''2 is an aliphatic alkylen... | 11/30/1993 |
| 5219884 | Immunosuppressant The present invention relates to an immunosuppressive agent which comprises at least one compound selected from the compounds of formula ##STR1## wherein R represents a hydrogen atom or an acyl, Y represents carbonyl or hydroxymethylene and represe... | 06/15/1993 |
| 5145611 | Carboxylic acid derivatives, and pharmaceutical compositions containing them Carboxylic acid derivatives of the formula ##STR1## R1 is alkoxy, alkylthio, alkylsulphinyl, alkulsulphonyl, alkylamino, cycloalkyl, or cycloalkoxy or optionally substituted aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl or arylamin... | 09/08/1992 |
| 4996356 | Carboxylic acids and methods of preparing the same Biodegradable and little skin-roughening carboxylic acids being an excellent surfactant in a wide pH range and having the general formula (1): ##STR1## wherein R is a linear or branched alkyl or alkenyl group containing from 4 to 34 carbon atoms... | 02/26/1991 |
| 4978759 | Process for the stereospecific synthesis of optically pure 4-amino-3-hydroxycarboxylic acid derivatives The process described makes it possible to obtain optically pure 4-amino-3-hydroxycarboxylic acids by means of a series of stereoselective steps. The starting material is an alpha-amino acid in the L or D configuration, with which Meldrum's acid is reacte... | 12/18/1990 |