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| Number | Title | Issue Date |
| 7476749 | Creatinol-fatty acid esters The present invention describes compounds produced from a Creatinol molecule and a fatty acid molecule. The compounds being in the form of Creatinol-fatty compounds bound by an ester linkage, or mixtures thereof produced by reacting Creatinol or derivatives of Creat... | 01/13/2009 |
| 6696606 | Solid phase synthesis of arylretinamides A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reactin... | 02/24/2004 |
| 6562988 | Methods and products relating to 16-HETE analogs The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesi... | 05/13/2003 |
| 6545170 | 2-amino-5, 6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors The present invention contains novel compounds useful as nitric oxide synthase inhibitors.... | 04/08/2003 |
| 6458837 | Lipophilic diesters of chelating agents The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to the present invention are stable lipophilic diesters compris... | 10/01/2002 |
| 6355629 | Prodrugs with enhanced penetration into cells The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to... | 03/12/2002 |
| 6353124 | Therapeutic compound-fatty acid conjugates The present invention provides therapeutic conjugates which comprise a therapeutic compound bound to one to three acyl groups derived from fatty acids. The therapeutic compounds are preferably non-steroidal anti-infiammatory agents which include a carboxy... | 03/05/2002 |
| 6310007 | 7,10,12-trihydroxy-8(E)-octadecenoic acid and derivatives and uses thereof The compound 7,10,12-trihydroxy-8(E)-octadecenoic acid (TOD) has been produced by bioconversion of ricinoleic acid by Pseudomonas aeruginosa PR3. TOD and derivatives thereof are useful for controlling biological organisms, such as fungi and insects.... | 10/30/2001 |
| 6281371 | Lipopolyamines, and the preparation and use thereof The present invention relates to new lipopolyamines (including salts thereof) characterised by a symmetrical, highly flexible lipophilic moiety having buffering capacity at physiological pH, and to the use thereof for the in vivo or in vitro introduction ... | 08/28/2001 |
| 6255503 | Water-soluble salts of dodecandioic acid and pharmaceutical and nutritional compositions containing same Water-soluble dodecandioates wherein the cationic moiety is selected from the group comprising the cations of basic aminoacids (e.g. lysine) and choline and orally or parenterally administrable compositions containing same, are disclosed.... | 07/03/2001 |
| 6231662 | Surface treatments for titanium dioxide and other industrial pigments An additive for enhancing the performance of industrial pigments. The additive improves dispersibility and is the reaction product of an amine, a fatty amine, and a polybasic acid.... | 05/15/2001 |
| 6180667 | Esters of acyl L-carnitines and pharmaceutical compositions containing same for treating endotoxic shock Esters of alkanoyl L-carnitines wherein the alkanoyl is a saturated or unsaturated, staight or branched alkanoyl having 2-26 carbon atoms, optionally ω-substituted with trialkylammonium, dialkylsulfonium, hydroxyl, carboxyl, halogen, methanesulfonyl and ... | 01/30/2001 |
| 5824812 | Polyfunctional cationic cytofectins, formulations and methods for generating active cytofectin: polynucleotide transfection complexes Amine containing compounds and their use in the generation of cytofectin:polynucleotide complexes for transfection of cells, formulations, counterions, and reaction conditions for maximizing the transfection include using cationic amine compounds that hav... | 10/20/1998 |
| 5792786 | Non-steroidal anti-inflammatory fatty acid conjugates and their therapeutic use thereof The present invention provides therapeutic conjugates which comprise a therapeutic compound bound to one to three acyl groups derived from fatty acids. The therapeutic compounds are preferably non~steroidal anti~inflammatory agents which include a carboxy... | 08/11/1998 |
| 5789371 | Amphoteric surfactants having multiple hydrophobic and hydrophilic groups According to the invention, an improved class of amphoteric surfactants having improved surfactant properties charaterized as mild and environmentally benign has been provided comprising a compound of the general formula: ##STR1## wherein R inde... | 08/04/1998 |
| 5719290 | Fatty acid analogs and prodrugs Novel derivatives of fatty acid analogs that have from one to three heteroatoms in the fatty acid moiety which can be oxygen, sulfur or nitrogen, are disclosed in which the carboxy-terminus has been modified to form various amides, esters, ketones, alcoho... | 02/17/1998 |
| 5705681 | Diquaternary compounds useful as bleach activators Diquaternary ammonium esters useful as bleach activators are disclosed as are bleach compositions comprising such an ester and peroxygen compound yield peroxide in solution.... | 01/06/1998 |
| 5662827 | Diquaternary compounds useful as bleach activators, and compositions containing them Disclosed are bleaching compositions comprising diquaternary ammonium esters which are useful as bleach activators with a peroxygen compound to yield peroxide in solution.... | 09/02/1997 |
| 5654452 | Lipophilic contrast agents for use in hepatocyte-selective oil-in-water emulsions Aromatic acid-derived lipophilic polyhalogenated compounds are provided for use as contrast agents in diagnostic imaging or as therapeutic agents. These compounds are particularly useful when incorporated into an oil-in-water emulsion for tissue-specific ... | 08/05/1997 |
| 5635608 | -carboxy caged compounds The invention relates to caged compounds for the study of biological processes, where the caged compound has a photoremoveable -carboxy-substituted o-nitrobenzyl group. Covalent attachment of the substituted o-nitrobenzyl to a parent compound yield... | 06/03/1997 |
| 5625085 | Esters of acyl L-carnitines and pharmaceutical compositons containing same for treating endotoxic shock Esters of alkanoyl L-carnitines wherein the alkanoyl is a saturated or unsaturated, straight or branched alkanoyl having 2-26 carbon atoms, optionally ω-substituted with trialkylammonium, dialkylsulfonium, hydroxyl, carboxyl, halogen, methanesulfonyl and... | 04/29/1997 |
| 5625067 | Cyclopentane ether derivatives, processes for their production, and their pharmaceutical use The invention relates to cyclopentane ether derivatives of Formula I ##STR1## their salts with physiologically compatible bases, as well as the -, ଲ- or γ-cyclodextrin clathrates, and also the liposome-encapsulated compounds of Formula ... | 04/29/1997 |
| 5399746 | Diquaternary bleach activators and compositions containing them Diquaternary ammonium esters useful as bleach activators are disclosed, as are bleach compositions comprising such an ester and a peroxygen compound which yields peroxide in solution.... | 03/21/1995 |
| 5393902 | Process for the preparation of bis(amidocarboxylic acids) A process is reported for the preparation of bis(amidocarboxylic acid) involving reacting an ester with an aminocarboxylate compound, the latter being formed from lactams or aminocarboxylic acids and salts thereof. The ester and aminocarboxylate compound ... | 02/28/1995 |
| 5068120 | Amine ester derivatives as low calorie fat mimetics Amine ester derivatives of the general formula: ##STR1## where B is an organic radical having from 2 to 12 carbons, each R is, independently, an aliphatic group having 1 to 30 carbons, X=H or R, independently, m=1 to 2, and n=1 to 7 comprise a new class o... | 11/26/1991 |
| 4849119 | Diamine carboxylates and lubricant and fuel compositions containing same N-Hydrocarbyl hydrocarbylenediamine carboxylates, which can be made by the reaction of the appropriate diamine and organic monocarboxylic acid, demonstrate friction reducing properties when formulated into lubricants, particularly lubricating oils, and fu... | 07/18/1989 |
| 4847303 | Tert-butylphenyl compounds useful as anti-inflammatory agents The present invention involves compounds having the structure: ##STR1## wherein: (a) --A1 is selected from the group consisting of --OH, --H, and --O2 CR; (b) --A2 is selected from the group consisting of unsubstituted or ... | 07/11/1989 |
| 4727180 | Antihypertensive polyhalohydroxylisopropyl phenylalkanoic and phenylalkenoic acids, amides and esters and intermediates thereto Polyhalohydroxyisopropyl phenylalkanoic and phenylalkenoic acids, amides, and esters, such as methyl 2-methoxy-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]benzenepro panoate, are useful as antihypertensive agents.... | 02/23/1988 |
| 4719084 | Mixtures of fatty acid ammonium salts with antifoaming and anticorrosion enhancing polyol fatty acids or salts thereof Water-soluble corrosion-inhibiting mixtures containing (a) one or more ammonium salts of fatty acids corresponding to the following general formula ##STR1## in which n=1 or 2 while R1, R2, R3 and R4 may be the ... | 01/12/1988 |
| 4670593 | Haloacetamidines and the herbicidal use thereof Dichloroacetamidines having the formula ##STR1## in which A and B are independently selected from hydrogen, fluorine, chlorine, bromine and methyl, provided that at least one of A or B is other than hydrogen; M is hydrogen or methyl; X is selected fr... | 06/02/1987 |
| 4659739 | Agricultural and horticultural guanidine-type fungicide and process for production thereof An agricultural and horticultural fungicide of low phytotoxicity comprising as an active ingredient an addition salt between a fungicidal guanidine compound and an acid having an oleophilic group with at least 9 carbon atoms in total. The acid addition sa... | 04/21/1987 |
| 4588823 | 9-substituted carbacyclin analogs Novel compounds of the following general formula: ##STR1##... | 05/13/1986 |
| 4529821 | Cyanoacylamide compounds N-Cyanoacylamide compounds of the formula I ##STR1## wherein R1 is hydrogen, alkyl, cycloalkyl or aryl, R2 is hydrogen or alkyl and R3 is hydrogen or alkyl and R3 is alkylene or arylenealkylene, are prepare... | 07/16/1985 |
| 4496584 | Amidine derivatives with anti-complement activity Amidino compounds represented by the formula ##STR1## and pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful antitrypsin, antiplasmin, antikallikrein and antithrombin agents. Having strong anti-Cl a... | 01/29/1985 |
| 4491535 | Hydrocarbon oxidate composition A hydrocarbon oxidate composition which comprises the reaction product of (a) a hydrocarbon oxidate, as described herein, or the metal salt thereof, with (b) a polyamine, as described herein, and (c) at least one copolymer of an olefin and a comonomer sel... | 01/01/1985 |
| 4430345 | Prostaglandins Novel bicyclo [2,2,1] heptanes and hept-2Z-enes are substituted at the 5-position by a 6-carboxyhex-2-enyl group or a modification thereof, and at the 6-position by an aldoxime or ketoxime group which is O-substituted by an aliphatic hydrocarbon residue, ... | 02/07/1984 |
| 4410519 | Tetraline derivatives, their production and pharmaceutical compositions containing them An optically active or racemic 2-amino-5-hydroxy-1,2,3,4-tetrahydronaphthalene wherein the nitrogen atom of the amino group carrier two alkyl groups, one of which is unsubstituted and the other is substituted by at least one functional group, or a ph... | 10/18/1983 |
| 4409213 | Prostanoid compounds and pharmaceutical compositions Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH-- or --(CH2)2... | 10/11/1983 |
| 4389413 | 9,11-Methano-13-aza-11a-carbathrombanoic acid analogues The 9,11-methano-13-aza-11a-carbathrombanoic acid analogues of the general formula: ##STR1## [wherein A represents ##STR2## (in which m is an integer of 1 to 6, the double bond between the carbon atoms in positions 5 and 6 in (iv) is in cis... | 06/21/1983 |
| 4320063 | Ammonium carboxylates Ammonium carboxylates having the general formula: ##STR1## wherein R is hydrogen or a substituted or unsubstituted hydrocarbon radical. The defined carboxylates promote the formation of alkane polyols in a homogeneous liquid phase mixture wherein hyd... | 03/16/1982 |
