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| Number | Title | Issue Date |
| 7745651 | Cationic lipids and methods of use The present invention provides compositions comprising cationic lipids, liposomes and nucleic acid-lipid particles comprising the cationic lipids, and methods of using such compositions, liposomes, and nucleic acid-lipid particles. ... | 06/29/2010 |
| 7420071 | Thermally stable surfactants and compositions and methods of use thereof There are provided novel thermally stable surfactants for use with fillers in the preparation of polymer composites and nanocomposites. Typically, surfactants of the invention are urethanes, ureas or esters of thiocarbamic acid having a hydrocarbyl group of from 10 ... | 09/02/2008 |
| 7314945 | Creatine-fatty acids The present invention describes compounds produced from a creatine molecule and a fatty acid molecule. The compounds being in the form of creatine-fatty acid compounds being bound by an anhydride linkage, or mixtures thereof made by reacting creatine or derivatives ... | 01/01/2008 |
| 7265143 | C-4 substituted retinoids C-4 substituted retinoic acid analogs, synthesis methods of C-4 substituted retinoic acid analogs and methods of using C-4 substituted retinoic acid analogs to treat various cancers and dermatological diseases and conditions. The C-4 substituted retinoic acid analog... | 09/04/2007 |
| 7164034 | Alpha2delta ligands for fibromyalgia and other disorders This invention relates to a method of treating a disorder selected from OCD, agoraphobia, agoraphobia without history of panic disorder, specific phobia, social phobia, PTSD, restless legs syndrome, premenstrual dysphoric disorder, hot flashes, and fibromyalgia by a... | 01/16/2007 |
| 7115728 | Human peroxisome proliferator activated receptor γ The present invention relates to a novel human peroxisome proliferator activated receptor, hPPARγ. hPPARγ differs from the mouse peroxisome proliferator activated receptor γ in the nucleotide sequence and the amino acid sequence. The invention provides isolated, ... | 10/03/2006 |
| 7098025 | Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor This invention relates to the isolation and cloning of the promoter and other control regions of human PPARγ gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the level o... | 08/29/2006 |
| 7007805 | Hydroxamate composition and method for froth flotation The invention relates to a hydroxamate composition for collection of minerals by froth flotation, the composition including an aqueous mixture of hydroxamate wherein the pH of the composition is at least 11 and a method of collecting mineral values from an aqueous o... | 03/07/2006 |
| 6972094 | Method of recovering fluorochemical surfactant Upon recovering a fluorochemical surfactant from a fluorochemical-containing aqueous solution, there is provided a method for recovering the fluorochemical surfactant from the aqueous solution containing the surfactant. In the method, the fluorochemical surfactant i... | 12/06/2005 |
| 6831186 | Lipoxin A4 analogs This invention is directed to lipoxin A4 analogs of the following formula (I) and (II): wherein R1, R2, R3, R4 and R5 are described herein. These analog... | 12/14/2004 |
| 6700006 | Internally plasticizing and crosslinkable monomers and applications thereof Novel compounds derived from traditional semi- drying and non-drying oils featuring internally plasticizing and crosslinkable properties are disclosed and claimed. Preferred embodiments include acrylate or methacrylate esters of hydroxy long-chain olefini... | 03/02/2004 |
| 6699499 | Amphiphilic materials and liposome formulations thereof Disclosed is a new structural class of amphiphilic molecules which incorporate a hydrophilic material or polymer attached, at spatially distinct sites, to at least two hydrophobic residues. Certain of the amphiphilic molecules comprise a plurality of hydr... | 03/02/2004 |
| 6649780 | Cationic lipids Cationic lipids are provided which are useful in the preparation of liposomes and other lipid vesicle carriers. The lipids of the invention are particularly useful as carriers of nucleic acids and other negatively charged substances, for delivery to cells... | 11/18/2003 |
| 6642398 | Mono-and disubstituted 3-propyl gamma-aminobutyric acids The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I ##STR1## The compounds are useful as therapeutic agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, ... | 11/04/2003 |
| 6600059 | Cytoprotective compounds The present invention provides compositions and methods for protecting cells from injury due to intrinsic membrane lysis, oxidation and/or invasion by destructive agents. Even more particularly, the present invention provides compositions and methods for ... | 07/29/2003 |
| 6562988 | Methods and products relating to 16-HETE analogs The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesi... | 05/13/2003 |
| 6458837 | Lipophilic diesters of chelating agents The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to the present invention are stable lipophilic diesters compris... | 10/01/2002 |
| 6451761 | N'N'-dichlorinated omega-amino acids and uses thereof A method of treating a CNS disorder in a subject in need of such treatment, the method comprising administering to the subject an effective amount of an N'N'-dichlorinated amino acid, peptide, peptidomimetic, amine, or a pharmacologically acceptable analo... | 09/17/2002 |
| 6423855 | Cytoprotective compounds The present invention provides compositions and methods for protecting cells from injury due to intrinsic membrane lysis, oxidation and/or invasion by destructive agents. Even more particularly, the present invention provides compositions and methods for ... | 07/23/2002 |
| 6355629 | Prodrugs with enhanced penetration into cells The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to... | 03/12/2002 |
| 6310174 | Primary alkanolamides This invention concerns a composition containing a dimerized or trimerized fatty acid amide of a primary alkanolamine that remains clear of suspended solids during storage, making mixtures containing the additive particularly useful to the metalworking in... | 10/30/2001 |
| 6310007 | 7,10,12-trihydroxy-8(E)-octadecenoic acid and derivatives and uses thereof The compound 7,10,12-trihydroxy-8(E)-octadecenoic acid (TOD) has been produced by bioconversion of ricinoleic acid by Pseudomonas aeruginosa PR3. TOD and derivatives thereof are useful for controlling biological organisms, such as fungi and insects.... | 10/30/2001 |
| 6284267 | Amphiphilic materials and liposome formulations thereof Disclosed is a new structural class of amphiphilic molecules which incorporate a hydrophilic material or polymer attached, at spatially distinct sites, to at least two hydrophobic residues. Certain of the amphiphilic molecules comprise a plurality of hydr... | 09/04/2001 |
| 6239297 | Sphingosine derivatives and medicinal composition The present invention intends to provide a derivative of sphingosine analogue that is able to regulate the functions of sphigolipid, and its pharmaceutical compositions. The present invention is the derivatives of sphingosine analogues represented by the ... | 05/29/2001 |
| 6235916 | Internally plasticizing and crosslinkable monomers and applications thereof Novel compounds derived from traditional semi-drying and non-drying oils featuring internally plasticizing and crosslinkable properties are disclosed and claimed. Preferred embodiments include acrylate or methacrylate esters of hydroxy long-chain olefinic... | 05/22/2001 |
| 6235914 | Amine and quaternary ammonium compounds made from ketones and aldehydes, and compositions containing them A process for making a tertiary amine ester of the following formula (I): ##STR1## the process comprising: (a) reacting a ketone or an aldehyde having the formula ##STR2## with a glycol to form a ketal or an acetal; (b) reacting the ketal or the acetal with a... | 05/22/2001 |
| 6231662 | Surface treatments for titanium dioxide and other industrial pigments An additive for enhancing the performance of industrial pigments. The additive improves dispersibility and is the reaction product of an amine, a fatty amine, and a polybasic acid.... | 05/15/2001 |
| 6221371 | Pseudoceramides, and dermatologic external preparations containing the same The present invention relates to pseudoceramide derivatives represented by formula(I) or (II): R1 --COCHR2 CONR3 R4 (I) R1 --CH(OH)CHR2 CONR3 R4 (II) wherein, each of R1 | 04/24/2001 |
| 6168913 | Coding combinatorial libraries with fluorine tags The present invention relates to coding combinatorial chemical libraries synthesized on a plurality of solid supports by attaching "tags" that comprise fluorine containing compounds in combinations and/or ratios. The tags can be decoded while attached to ... | 01/02/2001 |
| 6156899 | N-aryl-2-hydroxyalkylamido compositions for inducing/stimulating hair growth and/or retarding hair loss and/or for treating hyperseborrhea and/or acne Novel N-aryl-2-hydroxyalkylamido compounds having the formula (I): ##STR1## are well suited for inducing/stimulating hair growth and/or retarding hair loss and/or for therapeutically treating hyperseborrhea and/or acne.... | 12/05/2000 |
| 6072063 | Low-melting ester quats Ester quats of the formula (1) below are described: ##STR1## where RCO is an aliphatic acyl radical having 6 to 22 carbon atoms, R1 is a methyl radical, R2 is a C1 -C6 -alkyl radical, R3 is a C | 06/06/2000 |
| 6063369 | Quaternized hemp seed oil Quaternized hemp seed oil is incorporated into cosmetic compositions, such as shampoos, hair conditioners, hair sprays, mousses, gel or sculpting lotions, pomades, and skin creams and lotions. The hemp seed oil is saponified and quaternized under gentle c... | 05/16/2000 |
| 6046344 | Process for the preparation of hydroxypropylated quaternary ammonium compounds containing an ester functional group A process for the preparation of hydroxypropylated quaternary ammonium compounds containing an ester functional group, preferably a fatty acid ester functional group, of formula (I): ##STR1## in which: R denotes a saturated or unsaturated, linear or ... | 04/04/2000 |
| 6020489 | Cytoprotective fatty moiety compounds Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA2 and preventing oxidation. In particular, each compound has at leas... | 02/01/2000 |
| 5981580 | Fatty acid analogs and prodrugs Novel derivatives of fatty acid analogs that have from one to three heteroatoms in the fatty acid moiety which can be oxygen, sulfur or nitrogen, are disclosed in which the carboxy-terminus has been modified to form various amides, esters, ketones, alcoho... | 11/09/1999 |
| 5977390 | Fluorinated diester melt additives for thermoplastic polymers Fluorinated diesters useful for imparting repellency of low surface tension fluids to thermoplastic polymers of formulae Rf --O--C(O)--(CH2)n --C(O)--O--R1 ; Rf --O--C(O)--CH2 --CH(R2)--C(... | 11/02/1999 |
| 5952377 | Fatty acid analogs and prodrugs Novel derivatives of fatty acid analogs that have from one to three heteroatoms in the fatty acid moiety which can be oxygen, sulfur or nitrogen, are disclosed in which the carboxy-terminus has been modified to form various amides, esters, ketones, alcoho... | 09/14/1999 |
| 5929272 | Aliphatic epoxide-amine adducts with substantial side-chain, branching process for their preparation, and their use Epoxide-amine adducts having a proportion by mass of at least 20% of aliphatic epoxide or amine units which comprise at least one tertiary or quaternary carbon atom are disclosed. The adducts are employed as binders for coatings of relatively high environ... | 07/27/1999 |
| 5929110 | Fatty acid analogs and prodrugs Novel derivatives of fatty acid analogs that have from one to three heteroatoms in the fatty acid moiety which can be oxygen, sulfur or nitrogen, are disclosed in which the carboxy-terminus has been modified to form various amides, esters, ketones, alcoho... | 07/27/1999 |
| 5906922 | Delivery of nucleic acids The present invention provides a method for introducing nucleic acids into cells. The method involves exposing the cells to a compound having formula (1), in which w is a nucleic acid, x is a peptide or amino acid, y is a linker having a chain length equi... | 05/25/1999 |
