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| Number | Title | Issue Date |
| 7279563 | Compounds for protecting hydroxyls and methods for their use A hydrocarbyldithiomethyl-modified compound of the Formula: R1—O—CH2—S—S—R2 or a salt thereof wherein R1 is an organic molecule and R2 is a hydrocarbyl is useful for protecting and/... | 10/09/2007 |
| 7279448 | Poly(hydroxy thioether) vegetable oil derivatives useful as lubricant additives A novel class of chemically-modified vegetable oils is prepared by reacting epoxidized triglyceride oils with thiols. The resultant poly(hydroxy thioether) derivatives have utility as antiwear/antifriction additives for environmentally-friendly industrial oils and a... | 10/09/2007 |
| 7253296 | Acylated aminopropanediols and analogues and therapeutic uses thereof The invention relates to novel acylated aminopropanediols and the nitrogen and sulfur analogues thereof, pharmaceutical compositions comprising same, therapeutic uses thereof, in particular for the treatment of cerebral ischemia. The invention also provides a method... | 08/07/2007 |
| 6639088 | Compounds for protecting hydroxyls and methods for their use A hydrocarbyldithiomethyl-modified compound of the Formula: or a salt thereof wherein R1 is an organic molecule and R2 is a hydrocarbyl is useful for protecting and/or blocking hydroxyl groups in organic molecules such as nucleotides. The... | 10/28/2003 |
| 6013815 | Production and use of salts of 6,8-bis (amidiniumthio)-octanoic acid The invention relates to the production and purification of salts of 6,8-bis (amidiniumthio)octanoic acid, its enantiomers (+)-6,8-bis(amidiniumthio)octanoic acid and (-)-6,8-bis (amidiniumthio)octanoic acid and of the esters of these compounds as well ... | 01/11/2000 |
| 5811384 | Nonionic gemini surfactants Novel nonionic gemini surfactants are extremely effective emulsifiers for oil-in-water emulsions that provide improved detergency at even low concentration levels. The surfactants are characterized by the formula: ##STR1## wherein R1 is in... | 09/22/1998 |
| 5801260 | Carbonothioate phospholipid analogs as substrate of phospholipases and lipases Novel substrates of phospholipases, lysophospholipases and lipases are disclosed.... | 09/01/1998 |
| 5776973 | Palladium complexes and methods for using same in the treatment of psoriasis Novel palladium complexes and pharmaceutical compositions comprising the same are provided. Such complexes comprise (palladium)m (lipoic acid)n, wherein m and n are each independently 1 or 2. A process for preparing such complexes is... | 07/07/1998 |
| 5679697 | Palladium complexes and methods for using same in the treatment of tumors Novel palladium complexes and pharmaceutical compositions comprising the same are provided. Such complexes comprise (palladium)m (lipoic acid)n, wherein m and n are each independently 1 or 2. A process for preparing such complexes is... | 10/21/1997 |
| 5641735 | Bis(thio)ethylene ashless wear inhibitors and lubricating oils Oil soluble compounds having the formula: ##STR1## wherein R and R1 are independently cyano, alkoxycarbonyl or together form a carbocycle or alkylcarbocycle and R2 and R3 are independently alkyl, alkenyl, hydroxyalkyl... | 06/24/1997 |
| 5637616 | Method for treating diseases mediated by proteases A method for the topical or systemic treatment of disorders mediated by proteases which result in skin or mucosal lesions, and in particular, pemphigus, cicatricial pemphigoid, bullous pemphigoid, lichen planus, and canker sores, is disclosed wherein the ... | 06/10/1997 |
| 5463093 | Palladium complexes and methods for using same in the treatment of tumors or Psoriasis Novel palladium complexes and pharmaceutical compositions comprising the same are provided. Such complexes comprise (palladium)m (lipoic acid)n, wherein m and n are each independently 1 or 2. A process for preparing such complexes is... | 10/31/1995 |
| 5342977 | Aminosulfonic acid derivatives and processes for their preparation Salts of aminosulfonic acid derivatives of formula I ##STR1## wherein R1, R2 and R3 are each independently of the others an aliphatic hydrocarbon radical having from 7 to 21 carbon atoms, n is 0 or 1, As is the amidically ... | 08/30/1994 |
| 5292915 | Compounds containing carbonate groups and carbonyl groups and the preparation and use thereof The invention relates to compounds containing carbonate groups and carbonyl groups and having the general formula ##STR1## in which R stands for a C1 -C4 -alkyl radical, an aryl radical, or a radical R1, where R1... | 03/08/1994 |
| 5281722 | Preparation and use of salts of the pure enantiomers of alpha-lipoic acid The pure enantiomers of alpha-lipoic acid are obtained by formation of the diastereomeric salt pairs with the optical antipodes of alpha-methylbenzylamine in solution.... | 01/25/1994 |
| 5145611 | Carboxylic acid derivatives, and pharmaceutical compositions containing them Carboxylic acid derivatives of the formula ##STR1## R1 is alkoxy, alkylthio, alkylsulphinyl, alkulsulphonyl, alkylamino, cycloalkyl, or cycloalkoxy or optionally substituted aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl or arylamin... | 09/08/1992 |
| 5091558 | Naphthalene anti-psoriatic agents Psoriasis in mammals is relieved by topically administering naphthalenes of the formula: ##STR1## wherein: R1 is alkoxy, alkylthio, optionally substituted phenoxy or optionally substituted phenylthio; R2 is hydrogen, lower alkyl... | 02/25/1992 |
| 5082967 | Novel fatty acid analog enzyme substrates Novel diheteroatom-substituted fatty acid analog substrates of myristoylating enzymes are provided which contain oxyen and/or sulfur in place of two methylene groups in carbon positions from 3 to 13 in the fatty acid chain of a C13 -C14 | 01/21/1992 |
| 4978395 | Polymeric dispersing agent Polyaddition product the molecule of which is characterized by the presence of one group ##STR1## Method to prepare the above mentioned product and dispersions in polar and non polar diluents which contain the said product in addition with solid ... | 12/18/1990 |
| 4978759 | Process for the stereospecific synthesis of optically pure 4-amino-3-hydroxycarboxylic acid derivatives The process described makes it possible to obtain optically pure 4-amino-3-hydroxycarboxylic acids by means of a series of stereoselective steps. The starting material is an alpha-amino acid in the L or D configuration, with which Meldrum's acid is reacte... | 12/18/1990 |
| 4966732 | Process for the production of 1,2-dithiolan-3-pentanoic acid (thioctic acid) and 8-hydrocarbylthio-6-oxooctanoic acid 1,2-Dithiolane-3-pentanoic acid (D,L-thioctic acid) of the formula ##STR1## is prepared by a process comprising (a) reacting a 2-(3-alkylthiopropionyl)-cyclopentanone-1 of the formula ##STR2## where R is a C1 -C4 alkyl, phe... | 10/30/1990 |
| 4916230 | Process for preparing novel N-(acyloxy-alkoxy)carbonyl derivatives useful as bioreversible prodrug moieties for primary and secondary amine functions in drugs This invention relates to a new one-step process for preparation of novel N-(acyloxyalkoxy)carbonyl derivatives useful as bioreversible prodrug moieties for drugs having a primary or secondary amine function thereon.... | 04/10/1990 |
| 4867915 | 16-Substituted polyunsaturated hexadecanoic fatty acids Sixteen carbon atom carboxylic acids having 16-phenoxy or 16-phenylthio substituents, and 0, 1, or 4 triple bonds, methods of preparing them, and pharmaceutical preparations containing them. These compounds are useful as lipoxygenase inhibitors.... | 09/19/1989 |
| 4847303 | Tert-butylphenyl compounds useful as anti-inflammatory agents The present invention involves compounds having the structure: ##STR1## wherein: (a) --A1 is selected from the group consisting of --OH, --H, and --O2 CR; (b) --A2 is selected from the group consisting of unsubstituted or ... | 07/11/1989 |
| 4800044 | Intermediates for the production of 1,2-dithiolan acid (thioctic acid) Compounds of forumla XII ##STR1## wherein R1 is hydrogen and R2 is phenyl or benzyl are useful as intermediates in the preparation of 1,2-dithiolane-3-pentanoic acid (D,L-thioctic acid) of formula IX ##STR2##... | 01/24/1989 |
| 4746505 | Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands A bisamide-bisthiol ligand containing fatty acid substituted thiol useful for producing Tc-labelled radiodiagnostic imaging agents is described. The ligand forms a complex with the radionuclide 99m Tc suitable for administration as a radiopharm... | 05/24/1988 |
| 4727180 | Antihypertensive polyhalohydroxylisopropyl phenylalkanoic and phenylalkenoic acids, amides and esters and intermediates thereto Polyhalohydroxyisopropyl phenylalkanoic and phenylalkenoic acids, amides, and esters, such as methyl 2-methoxy-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]benzenepro panoate, are useful as antihypertensive agents.... | 02/23/1988 |
| 4722810 | Enkephalinase inhibitors Mercaptoalkanoyl and acylmercaptoalkanoyl compounds of the formula ##STR1## wherein n is an integer from one to fifteen possess enkephalinase inhibition activity and are useful as analgesic agents.... | 02/02/1988 |
| 4593120 | Naphthalene anti-psoriatic agents Psoriasis in mammals is relieved by topically administering naphthalenes of the formula: ##STR1## wherein: R1 and R2 are the same and are lower alkoxy, lower alkylthio, optionally substituted phenoxy or optionally substituted ... | 06/03/1986 |
| 4481148 | Hydroxyl containing liquid polymers Hydroxyl-containing liquid polymers having an aliphatic polymeric backbone and sulfide linkages near the terminal portions of the polymer molecule are prepared by polymerizing (1) at least one of selected vinylidene monomers having at least one terminal C... | 11/06/1984 |
| 4419298 | Ethanolamine salts of di-perfluoroalkyl group containing acids Ammonium and amine salts of acids having the formula ##STR1## wherein Rf is a perfluoroalkyl group; R1 is alkylene or substituted alkylene; X is --S--, --SO--, or --SO2 --; R2 is hydrogen, alkyl, aryl, subs... | 12/06/1983 |
| 4396552 | Novel metal mercaptides of esters of ଲ-mercaptoalkanols Metal mercaptides of the formula ##STR1## wherein Me is a metal, oxometal, alkoxymetal or organo-metal cation from the 1st-5th group of the periodic system, n is 0, 1 or 2, m is an integer from 1 to 4, R1 is hydrogen, alkyl, acyloxymethyl ... | 08/02/1983 |
| 4380498 | Sulfurized, transesterified oil additives and their use in a lubricating oil and a fuel Improved lubricant additive compositions, derived from fatty oils, comprise triglycerides which have been transesterified with polybasic carboxylic acids prior to sulfurization. Such additive compositions possess improved solubility in oils and impart imp... | 04/19/1983 |
| 4380499 | Sulfurized fatty oil additives and their use in a lubricating oil and a fuel Improved lubricant additive compositions, derived from fatty oils, comprise sulfurized, transesterified triglycerides. Such additive compositions possess improved solubility in oils and impart improved lubrication properties to both lubricant and fuel com... | 04/19/1983 |
| 4337353 | Novel carboxylic acids, benzoyl phenyl alkanoic acids and use thereof Novel carboxylic acids of the formula ##STR1## wherein Z is an aliphatic hydrocarbon chain selected from the group consisting of --(CH2)n -- and --CH.dbd.CH--(CH2)n-2 -- where the double bond may be at any ... | 06/29/1982 |
| 4301186 | Ammonium salts of -ketocarboxylic acids This invention relates to new ammonium salts of -ketocarboxylic acids, to their use for the production of amines in situ by photochemical decomposition and to photochemically hardenable coating compositions containing these ammonium salts.... | 11/17/1981 |
| 4180672 | 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom Organothiocyclopentanes of the formula ##STR1## wherein E represents >C.dbd.O or ##STR2## in which Z' represents a hydrogen atom, a hydroxyl group or a protected hydroxyl group; X represents --S--, --CH2 --, --CH.dbd.; represents ... | 12/25/1979 |
| 4180466 | Method of lubrication of a controlled-slip differential An improved method of lubrication of a controlled-slip differential comprises using a lubricant comprising major amounts of a hydrocarbon base stock and friction improving amounts of synthetic sulfurized oil consisting essentially of a cosulfurized blend ... | 12/25/1979 |
| 4177198 | Process for preparing alkaline earth metal mercaptides A process for preparing alkaline earth metal mercaptides, useful as synergists for organotin stabilizers in halogen containing resins such as polyvinyl chloride, the process comprising preparing an alkaline earth metal alkoxide by reacting the metal oxide... | 12/04/1979 |
| 4163106 | Prostaglandin precursors and processes for preparing the same 6-Alkenyl-bicyclo[3.1.0]hexanone compounds represented by the formula (I) ##STR1## wherein R1 represents an alkyl group having 1 to 4 carbon atoms or an aryl group, and R2 represents a substituted or unsubstituted alkyl group ha... | 07/31/1979 |
