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| Number | Title | Issue Date |
| RE39592 | Extended release growth promoting two component composition An extended release composition comprising a first composition comprising growth promoters and a second composition comprising growth promoters and a biodegradable polymer is described. A method of increasing weight gain in food animals utilizing the composition, a ... | 04/24/2007 |
| 6881728 | 14-β, 17-α-hydroxymethylandrostane derivatives as androgens Androgenic steroids having a (14β,17α-)-17-(hydroxymetheyl) configuration, useful for the preparation of male contraceptives and pharmaceutical formulations for the treatment of androgen insufficiency. ... | 04/19/2005 |
| 6596885 | 19-Nor steroids having a thiocarbonated chain in position 11beta, their preparation process and the intermediates of this process, their use as medicaments and compositions Novel compounds having a formula selected from the group consisting of ##STR1## wherein the substituents are defined as in the specification which are intermediates for the production of vinyl compounds having a remarkable anti-estrogenic and anti-prolife... | 07/22/2003 |
| 6498153 | Extended release growth promoting two component composition An extended release composition comprising a first composition comprising growth promoters and a second composition comprising growth promoters and a biodegradable polymer is described. A method of increasing weight gain in food animals utilizing the comp... | 12/24/2002 |
| 6369047 | Androgenic steroid compounds and a method of making and using the same An androgenic steroid compound of the formula: ##STR1## wherein: X Y, Z, R1, R2, R3, R5 and R6 are as defined herein.... | 04/09/2002 |
| 6090957 | Process for preparing neuromuscular blocking agents and intermediates useful therefor The present invention provides new process of preparing neuromuscular blocking agents. The process include preparing neuromuscular blocking agents using the compounds of formula I: ##STR1## wherein R1 is=O and X is halo; and formula II: ... | 07/18/2000 |
| 6080735 | Estra-1,3,5(10)-trien derivatives, processes for their preparation and pharmaceutical compositions containing these compounds This invention is relating to new estra-1,3,5(10)-trien-sulfamates carrying at the 3-position an R--SO2 --O--group, with R being an R1 R2 N--group in which R1 and R2, independently of each other, repr... | 06/27/2000 |
| 6046186 | Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use Novel compounds useful as inhibitors of estrone sulfatase are provided. The compounds have the structural formula (I) wherein r1 is an optional double bond, R1 and R2 are selected from the group consisting of hydrogen and lower alky,... | 04/04/2000 |
| 5986115 | 7-(.xi.-aminoalkyl)-estratrienes, process for their production, pharmaceutical preparations which contain these 7-(.xi.-aminoalkyl)-estratrienes as well as their use for the production of pharmaceutical agents This invention describes new, substituted 7-(.xi.-aminoalkyl)-estratrienes of general formula I ##STR1## in which side chain SK is a radical of partial formula ##STR2## as well as their physiologically compatible addition salts with organ... | 11/16/1999 |
| 5892069 | Estrogenic compounds as anti-mitotic agents The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found belo... | 04/06/1999 |
| 5843933 | 11ଲ-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents Compounds of formula I ##STR1## wherein X, R1, R2, R3 and R4 have the meanings indicated in the description, are described, as well as processes for their production, pharmaceutical preparations containing ... | 12/01/1998 |
| 5804576 | Derivatives of 5-androsten-17-ones and 5-androstan-17-ones Steroids of the formula: ##STR1## useful as cancer preventive agents, anti-obesity agents, anti-hyperglycemic agents, anti-aging agents, and anti-hypercholesterolemic agents and anti-auto-immune agents.... | 09/08/1998 |
| 5723455 | Antiandrogenic agents and related pharmaceutical compositions and methods of use Novel antiandrogenic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R1 through R10, a and b are as defined herein. Pharmaceutical compositions and methods for using the compo... | 03/03/1998 |
| 5714481 | Derivatives of 5-androsten-17 ones and 5-androstan-17-ones Steroids of the formula: ##STR1## useful as cancer preventive agents, anti-obesity agents, anti-hyperglycemic agents, anti-aging agents, and anti-hypercholesterolemic agents and anti-auto-immune agents.... | 02/03/1998 |
| 5700793 | Steroids useful as anti-cancer and anti-obesity agents | 12/23/1997 |
| 5597701 | Process for determining androstenone contents in adipose tissues A process and appropriate device are disclosed for determining the androstenone content of adipose tissues in clearly shorter times. The disclosed process has the following steps: (a) liquefying an adipose tissue sample by heating up to a predetermined te... | 01/28/1997 |
| 5273971 | 13-alkyl-11ଲ-phenylgonanes There are provided 13-alkyl-11beta-phenyl-gonanes of formula I ##STR1## wherein Z is an oxygen atom or N--OH; R2 is alpha- or beta-position methyl or ethyl; R1 is selected from heteroaryl radicals, cycloalkyl radicals, cycloalkenyl r... | 12/28/1993 |
| 5272140 | 11-aryl steroid derivatives The invention relates to 11-aryl steroid derivatives, having the structure ##STR1## wherein: R1, R2, R3, and R4 are as described in the specification and to processes for their preparation and to pharmaceutical... | 12/21/1993 |
| 5252565 | Haloethyl-substituted steroid enzyme inhibitors The present invention is directed to a group of compounds which are haloethyl substituted steroidal enzyme inhibitors. These compounds are useful as aromatase, 19-hydroxylase, and aldosterone biosynthesis inhibitors and they are prepared from the correspo... | 10/12/1993 |
| 5208263 | Anti-androgen compounds Disclosed are novel classes of anti-androgen including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities.... | 05/04/1993 |
| 5182381 | Intermediates for 3-keto-19-nor-Ɗ4,9 -steroids Novel 3-keto-19-nor-Ɗ4,9 -steroids of the formula ##STR1## and their non-toxic, pharmaceutically acceptable acid addition salts possessing a remarkable antiglucocorticoidal activity.... | 01/26/1993 |
| 5140106 | Process for the production of 3-deoxy-4-ene steroids A process for the production of 3-deoxy-4-ene steroids of the general formula I ##STR1## is described, in which R1, R2 and R3 mean a hydrogen atom or a methyl group, R4 represents a lower alkyl group, a phe... | 08/18/1992 |
| 5116830 | Stereoisomerically pure 17-ethynyl-estra-2-en-17ଲ-ol and the 17ଲ esters thereof, methods of preparation and uses This invention relates to a stereoisomerically pure Ɗ2 compound of the formula (I): ##STR1## wherein: R1 is hydrogen or --(C.dbd.O)--R2, wherein: R2 is an organic substituent selected from the group consisting ... | 05/26/1992 |
| 5086047 | Novel steroids A compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl, alkylthio and haloalkyl of 1 to 6 carbon atoms, alkenyl and alkynyl of 2 to 6 carbon atoms, option... | 02/04/1992 |
| 5064822 | Novel 3-keto-19-nor-Ɗ4,9 -steroids Novel 3-keto-19-nor-Ɗ4,9 -steroids of the formula ##STR1## wherein R1 is selected from the group consisting of naphthyl, phenylphenyl, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms optionally containing additiona... | 11/12/1991 |
| 5026693 | Novel 9-fluoro- or chloro-corticosteroid esters and a process for their preparation Novel esters of 9-fluoro- and chloro-corticosteroids of the formula ##STR1## wherein Y is chlorine or OR1, R1 and R2 represent an acyl group of 2-6 carbon atoms or a benzoyl group and where R1 and R2... | 06/25/1991 |
| 5001119 | 16-substituted androstanes and 16-substituted androstenes Compounds of the formula: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents.... | 03/19/1991 |
| 4945064 | Estrane and androstane derivatives, process for producing them and preparations containing these compounds Estrane and androstane derivatives of formula I ##STR1## wherein X is bromine, iodine, triphenyltin or trialkyltin of 1 to 6 carbon atoms per alkyl radical, Y represents two hydrogen atoms or methylene, Z represents two hydrogen atoms, oxo or alkylenediox... | 07/31/1990 |
| 4898694 | 17-Hydroxy-steroids Compounds of the formulae: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents.... | 02/06/1990 |
| 4870069 | 11ଲ-alkynyl-estrenes and -estradienes, their production and pharmaceutical preparations containing them 11ଲ-substituted steroids of the formula ##STR1## wherein A and B together represent a second bond between the 6-position and 7-position carbon atoms, or, respectively, are each H; X is O, two H atoms or hydroximino; Z is the residue of a pentagonal ... | 09/26/1989 |
| 4547493 | Novel 11ଲ-substituted-19-nor-steroids Novel 19-nor-steroids of the formula ##STR1## wherein R1 is an organic group of 1 to 18 carbon atoms optionally containing at least one heteroatom with the atom immediately adjacent the 11-carbon atom being carbon, R2 is a hydro... | 10/15/1985 |
| 4495102 | Aminoalkyl steroids Compounds of Formula I and II are useful as potent antiarrythmic agents without significant effect on cardiac output and blood pressure.... | 01/22/1985 |
| 4390530 | 3-Deoxy-Ɗ15 -steroids 3-Deoxy-Ɗ15 -steroids of the formula ##STR1## wherein R1 is hydrogen or an acyl group of a C1-15 hydrocarbon carboxylic acid, and R2 is ethynyl, chloroethynyl or propynyl are valuable progestationally effe... | 06/28/1983 |
| 4292251 | 11ଲ-Substituted steroids Novel and biologically active 11ଲ-substituted steroids of the oestrane series are disclosed having the formula ##STR1## wherein (a) R1 is O or (Y)(ଲZ), wherein Y is selected from the group consisting of H, unsaturated al... | 09/29/1981 |
| 4278668 | Pure 17 alpha-ethynyl(5 alpha), androst-2-ene,17 beta-cl, process for its preparation and therapeutical applications of the same The delta-2 isomer of the 17 alpha-ethynyl (5 alpha), 2-androsten, 17 beta-ol, unmixed with its delta-3 isomer; a process for making the therapeutic isomer and its 17 beta-acetate; and a method of treatment of endometriosis with the 17 beta-acetate of the... | 07/14/1981 |
| 4252719 | Steroid conversion method and products produced thereby Method for the removal of selected tertiary hydrogen atoms from 5 -steroids of the cholestane, androstane and pregnane series by chlorination of 5 -steroids esterified with selected iodoaryl substituted esterifying agents which direct a chlo... | 02/24/1981 |
| 4239681 | Androst-4-en-19-ols Derivatives of androst-4-en-19-ol are useful for enhancing libido and related psychic attitudes.... | 12/16/1980 |
| 4220775 | Preparation of 4-aza-17-substituted-5-androstan-3-ones useful as 5-reductase inhibitors A method of preparing a compound of the formula: ##STR1## where Formula (I) may also have the structure of partial Formula (III); wherein, ##STR2## R' is hydrogen or methyl; R" is hydrogen or ଲ-methyl; R'" is ଲ-methyl or hydroxy; Z i... | 09/02/1980 |
| 4219489 | Synthesis of steroids Method and compounds are provided for use in the synthesis of steroids wherein a polyolefin is provided having an initiating group having a chalcogen atom in juxtaposition to a double bond, so as to be capable of bond formation to close to form a ring and... | 08/26/1980 |
| 4183864 | Cobalt catalyzed steroid synthesis Steroid compounds obtained by co-oligomerization of a side chain functionalized 1,5-hexadiyne with bis(trimethylsilyl)acetylene catalyzed by cyclopentadiene cobalt dicarbonyl, CpCO(CO)2, via intermediate benzocyclobutene formation followed by i... | 01/15/1980 |
