Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7361645 | Androgenic 7-substituted 11-halogen steroids The invention relates to 11β-halogen steroids with general formula (I), whereby R11 is halogen, X—Y-Z represents a group with one of the two structures CH═C—C or CH2—C═C and the other radicals have the meaning that is indicated in th... | 04/22/2008 |
| 6989378 | Testosterone derivative The invention is the novel androgen (7α,17β)-7-methyl-17-[(1-oxoundecyl)oxy]estr-4en-3one (MENT undecanoate). This compound distinguishes favourably from other testosterone derivatives in that it has a good solubility in oily media. It particularly exhibits a good... | 01/24/2006 |
| 6677329 | Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11 Disclosed are novel, selective estrogens type having a steroid skeleton with a non-aromatic A-ring and a free or capped hydroxyl group at carbon atom No. 3. The estrogens satisfy general formula (I), in which R1 is H, (C1 -C3 | 01/13/2004 |
| 6649779 | Estrenes This invention provides a pharmaceutically acceptable salt of 3ଲ-hydroxy-5(10)-estrene-17-one 3-sulfate ester and a pharmaceutically acceptable salt of 3-hydroxy-5(10)-estrene-17-one 3-sulfate ester, which are useful as an estrogens.... | 11/18/2003 |
| 6458778 | Estradienes This invention provides estra-5(10),7-dien-3ଲ-ol-17-one or a pharmaceutically acceptable salt of its 3-sulfate ester, estra-5(10),7-dien-3ଲ-ol-17-one 3-glucuronide or a pharmaceutically acceptable salt thereof, estra-5(10),7-dien-3-ol-1... | 10/01/2002 |
| 5994568 | Estrenes for inducing hypothalamic effects The invention relates to estrene steroids, which bind to neuroepithelial receptors. The steroid is preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers.... | 11/30/1999 |
| 4923640 | Process for the production of 17-ethinyl-17ଲ-hydroxy-18-methyl-4,15-estradien-3-one and new intermediate products for this process A process for the production of 17-ethinyl-17ଲ-hydroxy-18-methyl-4,15-estradien-3-one is described comprising reacting a 17-enolester of formula II ##STR1## wherein R1 represents an alkyl radical with 1-3 carbon atoms and R | 05/08/1990 |
| 4921845 | 11-arylsteroid compounds The invention relates to new 11-arylsteroid compounds, having a strong antiprogestin and a weak or nonexistent antiglucocorticoid activity, to processes for preparing said compounds and also to pharmaceutical preparations which contain these derivatives a... | 05/01/1990 |
| 4871724 | Novel 11-aryloestrane and 11-arylpregnane derivatives The present invention is concerned with 11-aryloestrane and 11-arylpregnane derivatives, characterized in that these derivatives have the following structure: ##STR1## wherein R1 is an aryl group with an ##STR2## group as substit... | 10/03/1989 |
| 4745109 | Suicide inhibitors of aromatase Thiol-substituted synthetic steriod hormones or androgens having a testosterone ring system backbone are used to inhibit aromatase's catalyzed conversion of C19 androgens having a A4,3-ketone group to estrogens in the treatment of es... | 05/17/1988 |
| 4333928 | 16 -Alkyl steroids, their preparation, and pharmaceutical preparations thereof 16 -Alkyl steroids of the formula ##STR1## wherein R1 is hydrogen or methyl, R2 is hydrogen, alkyl, acyl, or glycosyl R3 is hydrogen or a substituted or unsubstituted, saturated or unsaturated lower hydrocarbon resi... | 06/08/1982 |
| 4212864 | Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5H analog thereof, where R is H or CH3 ; R1 is H or CH3 ; R2 is H or CH3 ; R3 | 07/15/1980 |
| 4150126 | Novel enol esters of steroids, compositions containing such compounds, processes for their preparation and methods of treatment therewith This invention relates to novel enol esters of steroids having an antitumor activity and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds and methods of treatment therewith.... | 04/17/1979 |
| 4052421 | 13-Ethinyl-steroids and processes for their manufacture A new class of 13-ethinyl-steroids is prepared by a novel process comprising Wittig reaction of a 13-formyl steroid with a chloro- or bromomethylenephosphorane and dehydrohalogenation of the intermediate 13-(2-halogenovinyl)steroid with an extremely stron... | 10/04/1977 |
| 4036695 | Process for the preparation of estrene-3,17-dione derivatives Estrene-3,17-diones of the formula ##STR1## wherein X is oxo, or ketalized oxo, preferably alkylenedioxy of 2-6 carbon atoms or o-phenylenedioxy; Ɗ is a carbon atom linked to the adjacent carbon atoms by a double bond and two single bonds; R1 | 07/19/1977 |
| 4002746 | Synthesis of gon-4-enes 1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound.... | 01/11/1977 |
| 3997574 | 9--methyl-steroids The compounds are 13-(lower)alkyl-9-methyl-17-propadienylgona-4-en-17ଲ-ol -3-ones and derivatives thereof, e.g. 9-methyl-17-propadienylestra-17ଲ-ol-3-one, and are useful as progestational agents.... | 12/14/1976 |
| 3983144 | Novel 11ଲ-alkyl steroids of the estrane series The present invention relates to novel steroids of the estrane series having the general formula I: ##SPC1## wherein R1 and R2 = an alkyl group having 1-4 carbon atoms, R3 = oxygen or (P)(ଲQ), wherein P = hydrogen ... | 09/28/1976 |
| 3972906 | Novel - 11-substituted steroids of the estrane series The present invention relates to novel 11-substituted steroids of the estrane series having the general formula ##SPC1## In which R1 = a free, esterified or etherified hydroxyl group or halogen; R2 = an alkyl group with 1-4 C-atoms; R | 08/03/1976 |
| 3963707 | Novel N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates This invention relates to novel N-halogenoalkyl-N-nitroso carbamates and N4 halogenalkyl-N4 -nitroso allophanates of steroid compounds, having an anti-tumor activity, and to the preparation thereof. The invention is also concerned wi... | 06/15/1976 |
| 3962291 | Total synthesis of 11-alkyl steroids A novel total synthesis of 11-alkyl steroids, utilizing readily available and inexpensive raw materials, is described. The resulting products are useful and novel pharmacological agents possessing, for example, selective hormonal properties.... | 06/08/1976 |
| 3944576 | Novel steroids of the oestrane series substituted in 7-position The invention relates to novel 7-substituted-steroids of the oestrane series of the general formula: ##SPC1## In which Ring A including carbon atom 6 is ##SPC2## R1 = an alkyl group with 1-4 C-atoms, R2 = oxygen or (Y)(ଲ... | 03/16/1976 |