Class 552/635 - Carbon or halogen bonded directly at the 2- or 4-position

Subclass of Class 552 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein carbon or halogen is bonded directly at
No. of patents: 28
Last issue date: 10/10/2006

Number	Title	Issue Date
7119081	Oestrogen-17-sulphamates as inhibitors of steroid sulphatase There is provided a compound of Formula I wherein X is a ring system; R1 is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; R	10/10/2006
6251887	17ଲ-aryl(arylmethyl)oxy(thio)alkyl-androstane derivatives The invention relates to 17ଲ-aryl(arylmethyl)oxy(thio)alkyl-androstane derivatives having general formula (I), wherein R1 is (H,OR), (H,OSO3 H) or NOR; with R being H, (C1-6)alkyl or (C1-6)acyl; each of R	06/26/2001
5723455	Antiandrogenic agents and related pharmaceutical compositions and methods of use Novel antiandrogenic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R1 through R10, a and b are as defined herein. Pharmaceutical compositions and methods for using the compo...	03/03/1998
5010071	Androstane derivatives Androstane derivatives of the general Formula I ##STR1## in which R1 represents a hydrogen atom or a methyl group, X and Y each mean hydrogen atoms or together a carbon-carbon bond, and R2 symbolizes a hydrogen atom or an alkyl group with...	04/23/1991
4898694	17-Hydroxy-steroids Compounds of the formulae: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents....	02/06/1990
4865766	Process for the preparation of 4-amino-androstenedione derivatives A process for the preparation of 4-aminoandrostenediones of formula (I) ##STR1## and pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is hydrogen and the other is hydrogen, C1 -C6 alkyl, ...	09/12/1989
4808616	6-substituted androsta-1,4-diene-3,17-diones The invention relates to 6-alkylidenandrosta-1,4-diene-3,17-dione derivatives, having the following general formula ##STR1## wherein each of R and R2, independently, is hydrogen or C1 -C6 alkyl and R1 is hy...	02/28/1989
4757061	4-amino androstendione derivatives and process for their preparation The invention discloses 4-substituted androstendione derivatives of the following formula (I) ##STR1## wherein R is amino or substituted amino or azido, one of R1 and R2 is hydrogen and the other is hydrogen, alkyl, alkenyl or a...	07/12/1988
4587235	Novel androstane derivatives, process for their production, and pharmaceutical preparations containing them Androstane derivatives of Formula I ##STR1## wherein is a single bond or a double bond, R1 is methyl or ethyl, R2 is hydrogen or alkyl of 1-8 carbon atoms, --X-- is --(CH2)n --, --CH.dbd.CH(CH2)m	05/06/1986
4459235	2-Cyanosteroids The invention relates to novel 2-cyanosteroids of Formula I which are useful for the induction of menses and the termination of pregnancy....	07/10/1984
4457925	Androstane derivatives, process for their production, and pharmaceutical preparations containing them Androstane derivatives of Formula I ##STR1## wherein ---- is a single bond or a double bond, R1 is methyl or ethyl, R2 is hydrogen or alkyl of 1-8 carbon atoms, --X-- is --(CH2)n --, --CH.dbd.CH(CH2)m...	07/03/1984
4346037	Base catalyzed acylation with enol esters This invention relates to processes for base catalyzed acylations using enol esters, for example, isopropenyl acetate. Particularly, the processes are useful for acylating acid sensitive alcohols including hydroxy steroids....	08/24/1982
4329296	Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5଱H analog thereof, where R is H or CH3 ; R1 is H or CH3 ; R2 is H or CH3 ; R3	05/11/1982
4321208	Preparation of directly iodinated steroid hormones and related compounds A process for the direct iodination of steroids and steroid hormones in the presence of hydrogen peroxide or chloramine-T is disclosed. The antigenicity and the specific receptor binding of directly iodinated estradiol 17-beta is identical to tritiated es...	03/23/1982
4317817	Novel steroid 5଱-reductase inhibitors Compounds of the following general formula are testosterone 5଱-reductase inhibitors rendering the compounds useful in the treatment of acne and oily skin and benign prostatic hypertrophy: ##STR1## wherein R is: .dbd.O, --OH, --OCO--alkyl C...	03/02/1982
4312864	Branched chain and cycloaliphatic esters of the androstane and destrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5଱H analog thereof. The steroid esters have androgenic, anabolic, oestrogenic or anti-oestrogenic properties depending upon the ri...	01/26/1982
4307087	Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## where R is H or CH3 ; R1 is H or CH3 ; R2 is H or CH3 ; R3 is H, OH, CH3 or ...	12/22/1981
4297350	Male contraceptive steroids and methods of use The steroids of the present invention have been found to be useful as male contraceptives when administered orally. Upon cessation of administration of the male contraceptive steroids of the present invention the male promptly regains normal fertility....	10/27/1981
4212864	Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5଱H analog thereof, where R is H or CH3 ; R1 is H or CH3 ; R2 is H or CH3 ; R3	07/15/1980
4198336	Chemical process for preparing androsta-4-ene 17଱-carboxylic acids This invention is a process for preparing 3-keto-androst-4-ene 17଱-carboxylic acids, androsta-1,4-diene 17଱-carboxylic acids and their 17଱-esters by reacting a corresponding 21-hydroxypregn-4-ene-3,20-dione, 21-hydroxypregna-1,4-diene-3,...	04/15/1980
4160027	Steroid cyanoketones and intermediates 2଱-Cyano-3-oxosteroids having a 4଱,5଱-epoxy group and alkylated in the 4- and/or 6-position, useful as interceptive agents, are prepared by alkaline cleavage of the corresponding steroido[2,3-d]isoxazoles....	07/03/1979
4150126	Novel enol esters of steroids, compositions containing such compounds, processes for their preparation and methods of treatment therewith This invention relates to novel enol esters of steroids having an antitumor activity and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds and methods of treatment therewith....	04/17/1979
4119625	Process for the manufacture of steroid carboxylic acids and the esters thereof The present invention provides a novel process for the manufacture of 17- and 17a-carboxylic acids of the androstane and D-homo-androstane series respectively, of the following partial formula of the ring D ##STR1## wherein R represents a hydrogen at...	10/10/1978
4052421	13-Ethinyl-steroids and processes for their manufacture A new class of 13-ethinyl-steroids is prepared by a novel process comprising Wittig reaction of a 13-formyl steroid with a chloro- or bromomethylenephosphorane and dehydrohalogenation of the intermediate 13-(2-halogenovinyl)steroid with an extremely stron...	10/04/1977
3980638	Testosterone derivatives Novel testosterone 17-ether 2,3-isoxazole and 2-cyano derivatives are disclosed as useful steroid enzyme inhibitors and for other pharmaceutical purposes....	09/14/1976
3966713	11ଲ-FLUOROANDROSTENES 11ଲ-Fluoroandrostenes of the formula ##SPC1## Wherein R1 and R2 are hydrogen atoms, methylene or another C--C bond; R3 is H or Cl, R4 is H, F or Cl; and X is carbonyl, ଲ-hydroxymethylene, or an ester...	06/29/1976
3963707	Novel N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates This invention relates to novel N-halogenoalkyl-N-nitroso carbamates and N4 halogenalkyl-N4 -nitroso allophanates of steroid compounds, having an anti-tumor activity, and to the preparation thereof. The invention is also concerned wi...	06/15/1976
3953429	Anaesthetic steroids of the androstance and pregnane series Steroids of the androstane and pregnane series possessing a 2଱-hydrogen or halogen or an alkyl group; a 3଱-hydroxy or acyloxy group, a 3ଲ-hydrogen or alkyl group; an 11ଲ-hydrogen or hydroxy group or an epoxy group linked also to th...	04/27/1976

PatentStorm

Quotables

PatentStorm News

Class 552/635 - Carbon or halogen bonded directly at the 2- or 4-position