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Class 552/540 - Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of six or more uninterrupted carbons (e.g., sterols, etc.)


Subclass of Class 552 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein carbon bonded directly at the 17 beta-position
No. of patents: 102
Last issue date: 05/06/2008


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NumberTitleIssue Date
7368583Process for recovery of plant sterols from by-product of vegetable oil refining
The process for recovery of plant sterols and tocopherols from deodorization distillates formed during chemical or physical refining of vegetable oils consists of the following steps: free fatty acids are removed from the deodorization distillate by vacuum distillat...
05/06/2008
7329429Bars and confectioneries containing cocoa solids having a high cocoa polyphenol content and sterol/stanol esters and processes for their preparation
Processes are provided for preparing ready-to-eat health bars such as chocolate granola bars and chocolate confectioneries such as dark or milk chocolate chews. The bars and confectioneries contain sterol ester(s) and/or stanol esters and cocoa solids having a high ...
02/12/2008
7323594Transfection reagents
Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro...
01/29/2008
7202372Process for the isolation of sterols and/or wax alcohols from tall oil products
The invention relates to a process for recovering sterols and/or wax alcohols from a crude tall oil based source material comprising sterols and/or wax alcohols in esterified form and fatty and/or rosin acids and optionally sterols and/or wax alcohols in free form, ...
04/10/2007
7189874Transfection reagents
Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting of N, O and S...
03/13/2007
7173154Transfection reagents
Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro...
02/06/2007
7166745Transfection reagents
Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro...
01/23/2007
7161055Method of extracting and isolating minor components from vegetable oil
A process for the separation and recovery of minor components from vegetable oil such as palm oil. Esterified palm oil is subjected to molecular distillation giving a concentrate rich in minor components. The concentrate is then adsorbed to adsorbents such as normal...
01/09/2007
7145039Transfection reagents
Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro...
12/05/2006
7144595Prepared foods containing triglyceride-recrystallized non-esterified phytosterols
A prepared food product for ingestion by mammals is described and methods for preparing such products. The food product includes an oxidation-resistant fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols. The fat...
12/05/2006
7122533Cosalane compounds and methods for their use
The present invention relates to methods, compounds and compositions for inhibiting effective binding of a chemokine to its cellular receptor. In one form of the invention, a method includes contacting a cellular population with an effective amount of cosalane or an...
10/17/2006
7067504Di-steroidal prodrugs of ethinyl estradiol
The present invention is a di-steroidal prodrug of ethinyl estradiol according to formula I: ...
06/27/2006
7067505Di-steroidal prodrugs of estradiol
The present invention is a di-steroidal prodrug of estradiol having the following formula: ...
06/27/2006
7048960High lignan flaxseed product and product by process
The present invention includes a high lignan concentrate (3% to 5% or greater) flax seed product, and product by process, which can be produced by 1) supplying a uniformly colored quantity of flax seeds with less than 5 percent visually darker seeds; 2) milling the ...
05/23/2006
6888014Dammarane sapogenins, their use as anti-cancer agents, and a process for producing same
This invention relates to a group of novel sapogenins, their use in anti-cancer applications, and to a process for their production. More particularly, this invention pertains to a novel group of dammarane sapogenins, PAM-120, PBM-110 and PBM-100 (the dammarance sap...
05/03/2005
6864229G protein coupled receptor (GPCR) agonists and antagonists and methods of activating and inhibiting GPCR using the same
The invention relates generally to G protein coupled receptors and in particular to agonists and antagonists of G protein receptors and methods of using the same. ...
03/08/2005
6846941Process for separating unsaponifiable valuable products from raw materials
Disclosed are processes for separating valuable products, including unsaponifiable materials, from any given matrix of raw materials that is mainly composed of saponifiable components and unsaponifiable components. Preferred methods include converting sodium or pota...
01/25/2005
6815553Birch bark processing and the isolation of natural products from birch bark
The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymer...
11/09/2004
6593319Fusidic acid derivatives
Novel 17,20-dihydrofusidic acid derivatives are used in pharmaceutical compositions for the treatment of infections, in particular in topical compositions for the treatment of skin or eye infections....
07/15/2003
6589945Use of sterolsulfates as active substances for producing means to inhibit serin proteases
A process for treating human skin by inhibiting serine protease formation involving contacting the skin with a composition containing a sterol sulfate....
07/08/2003
6562805Cosalane compounds and methods for their use
The present invention relates to methods, compounds and compositions for inhibiting effective binding of a chemokine to its cellular receptor. In one form of the invention, a method includes contacting a cellular population with an effective amount of cos...
05/13/2003
6482813Steroids substituted at the 11-position, process for their preparation, their use as medicament and the pharmaceutical compositions containing them
Compounds of formula ##STR1## for treating osteoporosis with minimal estrogenic activity are disclosed....
11/19/2002
6441206Use of organic acid esters in dietary fat
The invention concerns dietary fat compositions that contain the hydroxy acid or dicarboxylic acid or amino acid esters of a phytosterol and/or phytostanol, or the mixed esters formed with the alcohols, polyols or polyol (C2 . . . C22
08/27/2002
6399796Activation of a Diels-Alder reaction of a sterol 5,7-diene
An improved process and composition are disclosed for isolation of steroids containing a 5,7-diene functionality from a sterol mixture that comprises formation of a Diels-Alder reaction product of the ster-5,7-dienol in the presence of at least a catalyti...
06/04/2002
6392070Birch bark processing and the isolation of natural products from birch bark
The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polypheno...
05/21/2002
6388108Aminosterol compounds and uses thereof
Newly isolated aminosterol compounds and pharmaceutical compositions based on the aminosterol compounds are described. Methods for the treatment of various disorders, for example, a microbial infection, are also described....
05/14/2002
6177417Cholanic acid ring based 4-(trifluoroacetyl)phenyl derivatives, process for preparation and use thereof
The present invention relates to a cholanic acid ring based 4-(trifluoroacetyl)phenyl derivatives of the following formula 1, process for preparation and use thereof. The cholanic acid ring based 4-(trifluoroacetyl)phenyl derivatives of the present invent...
01/23/2001
6046186Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use
Novel compounds useful as inhibitors of estrone sulfatase are provided. The compounds have the structural formula (I) wherein r1 is an optional double bond, R1 and R2 are selected from the group consisting of hydrogen and lower alky,...
04/04/2000
6040468Method of preparing 16଱, 17଱-dialkylated steroids
16଱, 17଱-dialkylated steroids are prepared by reacting a 16଱-alkyl-17(20)-enyl-20-silyl ether with an alkylating agent and an enol silyl ether cleaving agent in a suitable solvent....
03/21/2000
5948925Cationic amphiphiles containing linkers derived from neutral or positively charged amino acids
Cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. There are provided also therapeutic compositions prepared typically by contacting a dispersion of one or more cationic amphiphiles with ...
09/07/1999
5942634Cationic amphiphiles for cell transfections
Cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. There are provided also therapeutic compositions prepared typically by contacting a dispersion of one or more cationic amphiphiles with ...
08/24/1999
5925628Cationic amphiphiles for intracellular delivery of therapeutic molecules
Cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. There are provided also therapeutic compositions prepared typically by contacting a dispersion of one or more cationic amphiphiles with ...
07/20/1999
5760255Process for the conversion of hydroxyl groups into the corresponding fluorine compounds
The invention is drawn to a process for the conversion of primary and secondary alcohols into the corresponding fluorine compounds in the presence of an organic solvent, 2-3 equivalents of a strong base and perfluoroalkylsulphonyl fluorides, such as perfl...
06/02/1998
5723455Antiandrogenic agents and related pharmaceutical compositions and methods of use
Novel antiandrogenic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R1 through R10, a and b are as defined herein. Pharmaceutical compositions and methods for using the compo...
03/03/1998
5716800Anti-acne composition containing a Poria cocos wolf extract
The invention concerns the use of an organic or hydro-organic extract of Poria cocos Wolf fungi for the preparation of a cosmetic and/or pharmaceutical composition, in particular a dermatological composition, for the treatment of acne and oily skin. The p...
02/10/1998
5712109Antifungal agent produced by arthrinium arundinis ATCC 74359
There is disclosed a compound having the formula ##STR1## which is produced by the fungus, Arthrinium arundinis ATCC 74359, and exhibits antifungal activity....
01/27/1998
564187717-଱ and 17-ଲ substituted acyl-3-carboxy-3, 5-dienes and use in inhibiting 5-଱-reductase
Invented are 17଱ and 17ଲ-substituted acyl-3-carboxy-3,5-diene analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-଱-reductase. Als...
06/24/1997
564176517-댚nd 17-ଲsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-଱-reductase
Invented are 17଱ and 17ଲ-substituted acyl-3-carboxy-3,5-diene analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-଱-reductase. Als...
06/24/1997
5637722Ester syntheses and transesterifiable xanthate reactants therefor
"Esters" are synthesized by reacting a nucleophile with a propargyl xanthate advantageously having the formula (I): R3 --C.tbd.C--CR1 R2 --S--CS--Y--R (I) in the presence of at least one acid, Bronsted or otherwise, and at ...
06/10/1997
5637691Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
Compounds having a broad range of antimicrobial activity generally have a structure including asteroid nucleus with a cationic, preferably polyamine, side chain (X) and an anionic side chain (Y). The invention is also directed to compounds of the Formula ...
06/10/1997
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