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| Number | Title | Issue Date |
| 6579864 | 3-methylene steroid derivatives The invention concerns a 3-methylene steroid derivative having general formula (1) wherein R1 is H or together with R3 forms a ଲ-epoxide or R1 is absent if there is a 5-10 or 4-5 double bond; R2 is (C... | 06/17/2003 |
| 6136800 | 17-Difluoromethylene-estratrienes This invention describes the new 17-difluoromethylene-estratrienes of general formula I ##STR1## in which R1 is a hydrogen atom or a C1 -C10 alkyl group, R5 is a methyl or ethyl group, and R2 is a hyd... | 10/24/2000 |
| 6046185 | 6,7-oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substituti... | 04/04/2000 |
| 6043236 | Estrogens Compounds of the formula I ##STR1## a process for their preparation, their use in the treatment of autoimmune disorders as well as new intermediates for their preparation.... | 03/28/2000 |
| 5994333 | Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a pregnane or cholane steroid, or a pharmaceutical composition containing a vomeropherin, such that... | 11/30/1999 |
| 5916975 | Process for epoxidising prochiral olefins and a catalyst therefor and intermediates for making the catalyst A process for enantioselectively epoxidising a prochiral olefin, which process comprises reacting a prochiral olefin with a source of oxygen in the presence of a salen catalyst and a source of an electron donating ligand, characterized in that the donor l... | 06/29/1999 |
| 5824811 | 22-Thiavitamin D3 derivatives Compounds of the general formula: ##STR1## wherein R1 represents a C1-10 alkyl group which may be substituted by one or more hydroxyl groups, R2 represents a hydrogen atom or a hydroxyl group, and R3 represents a hydr... | 10/20/1998 |
| 5502183 | Steroid intermediates and processes for their preparation Novel steroids having a 9-hydroxy or a 9-carbonate substituent can be prepared from 9-hydroxyandrostenedione and can be utilized in the synthesis of commercially valuable corticosteroids such as betamethasone. The 9-carbonates ... | 03/26/1996 |
| 5449795 | Process for synthesis of steroidal allylic tert. alcohols A method for the preparation of a steroidal allylic tertiary alcohol is disclosed which involves the deprotonation of a sulfoxide with a strong base which is capable of deprotonating the methine proton which is to the sulfoxide, in an inert solven... | 09/12/1995 |
| 5032586 | 7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase Invented are carboxyl and carboxyl alkyl ester substituted 7-keto and hydroxy analogues of synthetic steroidal compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5--reductase. ... | 07/16/1991 |
| 4530795 | Process for preparation of 16 -methyl corticoids from Ɗ16 -steroids This invention discloses a general process for the production of corticoids from respective steroid-type compounds having a double bond from C-16 to C-17. The invention provides a viable alternative synthesis of 17-hydroxy-progesterones and like co... | 07/23/1985 |
| 4360470 | Process and intermediates for the synthesis of Vitamin D3 metabolites and chenodeoxycholic acid The present disclosure is directed to a process for the synthesis of chenodeoxychloic acid, 25-hydroxycholesterol and 1,25-dihydroxycholesterol from 17-keto steroids. A cholic acid side chain is stereospecifically introduced by reaction of the appr... | 11/23/1982 |
| 4310467 | Process and intermediates for the synthesis of vitamin D3 metabolites The present disclosure is directed to a process and intermediates for the synthesis of Vitamin D3 metabolites such as 1,25-dihydroxycholecalciferol, 25-hydroxycholecalciferol and 24R,25-dihydroxycholecalciferol from 17-keto steroids via interme... | 01/12/1982 |
| 4197296 | Androstanes Steroids of the androstane series are described which possess a 3-hydroxy group, a 5- or 5ଲ- hydrogen atom, a 10- methyl group, an 11- substituted amino group. The 17-position may be unsubstituted or substituted by a methyl or e... | 04/08/1980 |
| 4092310 | Difluorosteroids and processes for their manufacture A novel group of 18,18-difluorosteroids of the general formula ##STR1## wherein St, R1 and R2 have the meanings given hereinafter is produced by a chemically novel process characterized in that a corresponding 18-oxo compound is... | 05/30/1978 |
| 3947409 | 16-Alkyl-1,4,9(11)-pregnatrienes and 9,11-epoxides thereof The invention disclosed herein relates to processes and intermediates useful in the preparation of certain 16-lower alkyl-1,4-pregnadiene compounds. It is particularly concerned with novel methods of preparing 16-lower alkyl-9-fluoro-11ଲ... | 03/30/1976 |
