Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 6949531 | 14 β, 16, 17-methylene steroids as novel androgens Disclosed are androgenic steroids of the (14β,17α)-17-(hydroxymethyl) type. The invention relates to an improvement thereof, which is based on the presence of a β-oriented, annellated cyclopropyl group which includes carbon atoms 16 and 17 of the steroid skeleton... | 09/27/2005 |
| 6313180 | Steroid compounds having contraceptive and anti-osteoporosis activity The invention relates to a steroid compound having the formula (I) ##STR1## comprising a ring E, said ring sharing carbon atoms at position 16 and 17 with the five-membered ring D and being with respect to said D-ring. In addition, the carbon atom... | 11/06/2001 |
| 6077873 | Steroid compounds having contraceptive and anti-osteoporosis activity The invention relates to a steroid compound having the formula (I) ##STR1## comprising a ring E, said ring sharing carbon atoms at position 16 and 17 with the five-membered ring D and being with respect to said D-ring. In addition, the carbon... | 06/20/2000 |
| 5703066 | Progestationally active 19,11-bridged 4-estrenes In this invention, the new etheno- and ethano-19,11-bridged 4-estrenes of general formula I ##STR1## are described, in which W, R1, R2, R6a, R6b, R7, R14, R15, R16 | 12/30/1997 |
| 5631249 | Estrogen nucleus derivatives for use in the inhibition of sex steroid activity Novel compounds for the inhibition of sex steroid activity for the treatment of both androgen-related and estrogen-related diseases include for example 15- and 16-halo substituted compounds such as: ##STR1## The compounds are characterized by an estr... | 05/20/1997 |
| 5407928 | 11ଲ-aryl-gona-4,9-dien-3-ones This invention relates to 11ଲ-aryl-gona-4,9-dienes of the general formula I ##STR1## wherein the variables are defined in the specification. The compounds are progesterone antagonists and are suitable for inducing labor or an abortion.... | 04/18/1995 |
| 5240814 | Curable, heat activatable transfer toners A non-electroscopic prolonged tack toner for transferring toned images to an image receptor at low temperatures with improved back transfer characteristics.... | 08/31/1993 |
| 5166199 | 11ଲ-aryl-16,17-cyclohexano-estra-4,9-dienes 11.sym.-Aryl-16,17-cyclohexano-estra-4,9-dienes of formula ##STR1## wherein R1 is H or a methyl group; R2 is --OCH3, --SCH3, --N(CH3)2, --NHCH3, --CN, --CHO, --COCH... | 11/24/1992 |
| 5162312 | 11ଲ-substituted 16, 17-methylene-estra-4,9-dien-3-ones 11ଲ-substituted-16, 17-methylene-estra-4,9-dien-3-ones of formula I ##STR1## wherein R1 is a methyl or ethyl group; R2 is H; a C1-6 -alkyl, -alkoxymethyl, -alkanoyl or -alkoxcarbonyl group ; 2-meth... | 11/10/1992 |
| 5073548 | 11 ଲ-substituted progesterone analogs A 11ଲ-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R1 is H, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, OH, OC(O)CH3, or OC(O)R5 , wherein R5 is C2... | 12/17/1991 |
| 4954490 | 11 ଲ-substituted progesterone analogs A 11ଲ-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R1 is H, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, OH, OC(O)CH3, or OC(O)R5, wherein R5 is C2-... | 09/04/1990 |
| 4536401 | 11ଲ-aryl estradienes, processes for their production and pharmaceutical preparations containing them Compounds of the formula I ##STR1## wherein R1 is ##STR2## wherein RI and RII each independently is alkyl of 1-4 carbon atoms, or RI and RII together with the connecting N-atom form a 5... | 08/20/1985 |
| 4474702 | [16,17-a]Cyclopentano pregnenes Antiinflammatory activity is exhibited by pregnenes having the structural formula ##STR1## wherein R1 is hydrogen, hydroxy, halogen, or acyloxy; R2 and R3 are each hydrogen, R2 and R3 are each methyl,... | 10/02/1984 |
| 4447426 | Steroid monohydrates, formulations containing same and method A monohydrate of a steroid having the structure ##STR1## and the 1,2-dehydro derivatives thereof, is provided which monohydrate is in the form of a particulate material having a stable average particle size of less than about 20 microns. Cream and lo... | 05/08/1984 |
| 4391755 | Steroid monohydrates, formulations containing same and method A monohydrate of a steroid having the structure ##STR1## and the 1,2-dehydro derivatives thereof, is provided which monohydrate is in the form of a particulate material having a stable average particle size of less than about 20 microns. Cream and lo... | 07/05/1983 |
| 4322349 | Process for preparing 6-methylene steroids A process for preparing a 6-methylene-Ɗ4 -3-keto steroid of the formula ##STR1## wherein R is hydrogen, alkoxy of up to 6 carbon atoms or acyloxy of up to 6 carbon atoms wherein the acyl group is that of a carboxylic acid, and R' is the C... | 03/30/1982 |
| 4219488 | Process for preparing steroidal [16,17-b]naphthaleno-21-carboxylic acid esters Steroidal [16,17-b]naphthaleno-21-carboxylic acid esters can be prepared from 21-hydroxy-Ɗ16 -steroids by converting the starting steroid to a 21-carboxylic acid ester -Ɗ16 -steroid and then fusing the tetrahydronaphthalene ... | 08/26/1980 |
| 4213912 | Process for preparing steroidal [16,17-d]cyclohexene-21-carboxylic acid esters Steroidal [16, 17-d]cyclohexene-21-carboxylic acid esters can be prepared from 21-hydroxy-Ɗ16 -steroids by first converting the starting steroid to a 21-carboxylic acid ester -Ɗ16 -steroid and then fusing the cyclohexene rin... | 07/22/1980 |
| 4164504 | Steroidal[16,17-b]naphthaleno-21-carboxylic acid esters Steroids having the formula ##STR1## wherein R1 is alkyl, aryl, or arylalkyl; R2 is hydrogen or halogen; R3 is hydrogen, methyl or fluorine; R4 is chlorine, fluorine or hydroxy and R5 is hydrogen... | 08/14/1979 |
| 4160772 | Steroidal[16,17-d]cyclohexene-21-carboxylic acid esters Steroids having the formula ##STR1## wherein R1 is alkyl, aryl or arylalkyl; R2 and R3 are the same or different and are hydrogen, alkyl or aryl; R4 is hydrogen and R5 is hydroxy or together R | 07/10/1979 |
| 4091036 | 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 , 17 -b]naphthalenes and derivatives pg,1 Steroids having the formula ##STR1## wherein X is ##STR2## R1 is alkyl, aryl or acyloxyalkyl; R2 and R3 are the same or different and are hydrogen, alkyl, alkoxy, carboalkoxy, formyl, ##STR3## hydr... | 05/23/1978 |
| 4031075 | Alkylated pregnanes and process for obtaining same The invention relates to novel 21-alkylated steroids of the pregnane series having the formula: ##STR1## WHEREIN X = H or halogen; Y = h2, h(oh), h(oacyl), O or H(halogen); R1 = an alkyl group having 1-4 C-atoms; R2 = r | 06/21/1977 |
| 3994935 | Steroidal 16ଲ-alkyl[16,17-b]naphthalenes Novel steroids having the structure ##SPC1## And the 1,2-dehydro derivatives thereof, wherein R1 is chlorine, fluorine, or hydroxy and R'1 is hydrogen or R1 and R'1 together are =O; R2 is hydrogen or ... | 11/30/1976 |
| 3979417 | 1 H-androsta(16,17)cyclopentene-3-ones Steroids having the formula ##SPC1## And the 1,2-dehydro derivatives thereof, wherein R1 is phenyl, naphthyl, or substituted phenyl or naphthyl, have useful anti-inflammatory activity.... | 09/07/1976 |
| 3944584 | Steroidal (16,17-d)cyclohexenes A series of novel steroidal[ 16, 17-d]cyclohexenes having a 9-fluoro group is disclosed herein for use as anti-inflammatory agents.... | 03/16/1976 |
| 3937720 | Steroidal[16,17-ଲ]naphthalenes Novel steroids having the structure ##SPC1## And the 1,2-dehydro derivatives thereof, wherein R1 is chlorine, fluorine, or hydroxy and R'1 is hydrogen or R1 and R'1 together are =0; R2 is hydrogen or ... | 02/10/1976 |
