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| Number | Title | Issue Date |
| 8044220 | High shear process for the production of butadiene sulfone Use of a high shear mechanical device incorporated into a process for the production of sulfolene as a reactor device is capable of decreasing mass transfer limitations, thereby enhancing the sulfolene production process. A system for the production of sulfolene fro... | 10/25/2011 |
| 7601850 | Phenyl-thiophene type vitamin D receptor modulators The present invention relates to novel, non-secosteroidal, phenyl-thiophene compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1α,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis. | 10/13/2009 |
| 7518001 | Radically polymerizable sulfur-containing compound and radically polymerizable sulfur-containing polymer The invention relates to a radically polymerizable sulfur-containing compound having a group represented by formula (1) and at least one selected from among groups represented by formulae (2) to (4), a radically polymerizable sulfur-containing polymer obtained by su... | 04/14/2009 |
| 7488834 | Organic semiconductors A molecule including a chain-like core region having two ends and having at least three conjugated aromatic rings; and including at the two ends, branched groups R1 and R2 respectively, each including a C5- to C20-alkyl gr... | 02/10/2009 |
| 7351841 | Heterocyclic compounds and thrombopoietin receptor activators A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C | 04/01/2008 |
| 7332623 | Aryl-substituted acyclic enediyne compounds This invention provides aryl-substituted acyclic enediyne compounds of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein | 02/19/2008 |
| 7323608 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds One aspect of the present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-sulfur bond between the sulfur atom of a t... | 01/29/2008 |
| 7321044 | Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens The invention relates to intermediate products and a new process for the production of benzocycloheptene C. The process for the production of its new intermediate products according to the invention starts from eco... | 01/22/2008 |
| 7241904 | Pentafluorosulfanyl-substituted thienothiophene monomers and conducting polymers Disclosed are monomers of the formula: ... | 07/10/2007 |
| 7205414 | Process for the Kumada coupling reaction A method for the formation of 3-alkylthiophenes or 3-arylthiophenes from 3-halothiophenes. More particularly, improvements on the Kumada coupling reaction for the production of 3-alkylthiophenes or 3-arylthiophenes by reacting a 3-halothiophene with an alkylmagnesiu... | 04/17/2007 |
| 7202247 | 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders The invention relates to compounds, pharmaceutical compositions and methods of using compounds of the general formula or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the ... | 04/10/2007 |
| 7122294 | Photoacid generators with perfluorinated multifunctional anions Photoacid generators (PAGs) comprising photoactive moieties and perfluorinated, multifunctional anionic moieties (or incipient anionic moieties) are disclosed which provide photoacids with high acid strength, low volatility and low diffusivity. The present invention... | 10/17/2006 |
| 7115784 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or a... | 10/03/2006 |
| 7087599 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 08/08/2006 |
| 7084136 | Drug composition antagonistic to both PGD/TXA receptors A compound of the formula (I): wherein A is alkylene optionally having an unsaturated bond; R is —C(═O)—R1; R1 is hydroxy or the like; m is 0 or 1; p is 0 or 1; X1 and X | 08/01/2006 |
| 6878801 | Optically active polythiophenes Novel polythiophenes which exhibit strong main chain absorption in the ultraviolet to visible region, show optical activity depending on the polymeric chain alone, and comprise as repeating units thiophene rings containing chiral substituent groups, and are represen... | 04/12/2005 |
| 6867323 | Cross-coupling reaction of organosilicon nucleophiles Improved methods for generating a —C—C— bond by cross-coupling of a transferable group with an acceptor group. The transferable group is a substituent of an organosilicon nucleophile and the acceptor group is provided as an organic electrophile. The reaction i... | 03/15/2005 |
| 6849384 | Photoacid generators, photoresist compositions containing the same and pattering method with the use of the compositions Photoacid generators comprising sulfonium salt compounds represented by the following general formula (2) wherein R1 and R2 represent each an alkyl group optionally having oxo, or R1 and R2 may be cyclized together to form... | 02/01/2005 |
| 6825360 | Bicyclic aromatic compounds The invention relates to novel bicyclic aromatic compounds which have the general formula (I): as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (d... | 11/30/2004 |
| 6780998 | Substituted 2-aminoalkyl-1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same The oxidation hair dye precursor composition contains from 0.005 to 20.0 percent by weight of one or more coupler compounds and from 0.005 to 20.0 percent by weight of one or more developer compounds. The one or more developer compounds include at least one substitu... | 08/24/2004 |
| 6617462 | Bithienylnaphthalene-and bis(3,4-ethylenedioxythienyl)naphthalene-based monomers and polymers Electropolymerizable monomers of the formulas ##STR1## wherein R1, R2 and R3 are selected from the group consisting of --H, --O(CH2)n CH3, ##STR2## wherein n has a value of 0 to 11 ... | 09/09/2003 |
| 6482958 | Methods for the preparation of 4-hydroxy benzothiophene The present invention is concerned with a novel process for the preparation of a hydroxybenzothiophene that is an intermediate for synthesizing pharmaceutically active substances, e.g. 5-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-7-benzothiophenylmethyl]... | 11/19/2002 |
| 6465647 | Oxygen, sulfur and nitrogen substituted cyclohexene and cyclohexane derivatives having retinoid-like biological activity Compounds of the Formula 1, Formula 2, Formula 3 and Formula 4 wherein the symbols have the meaning assigned to them in the disclosure have retinoid-like biological activity. ##STR1##... | 10/15/2002 |
| 6465646 | 1-alkoxy and 1-acyloxy substituted cyclohex-1-ene compounds and sulfur and 1-alkoxycarbonyl analogs having retinoid-like biological activity Compounds of Formula 1 and of Formula 2 ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinoid antagonist or retinoid negative hormone like biological activity.... | 10/15/2002 |
| 6372693 | Substituted 2-(3-alkenyl-benzoyl)-cyclohexane-1,3-diones The invention relates to 2-(3-alkenylbenzoyl)cyclohexane-1,3-diones of the formula I ##STR1## where the variables have the following meanings: R1, R2 are hydrogen, nitro, halogen, cyano, thiocyanato, alkyl, haloalkyl, alkoxyalkyl, al... | 04/16/2002 |
| 6355806 | ACETYLENES DISUBSTITUTED WITH A 5 ALKYL, ARYL OR HETEROARYL SUBSTITUTED DIHYDRONAPHTHYL GROUP AND WITH AN ARYL OR HETEROARYL GROUP HAVING RETINOID-LIKE WITH AN ARYL OR HETEROARYL GROUP HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY Compounds of the formula ##STR1## wherein the symbols have the meaning described in the specification, have retinoid-like biological activity.... | 03/12/2002 |
| 6355365 | Molecular compound, luminous material using the same, and luminous element Provided is a new molecular compound excellent in luminous property, which has a molecular structure wherein a thiophene ring and a benzene (or naphthalene) ring are directly bonded to each other, as a molecular compound making it possible to control its ... | 03/12/2002 |
| 6337417 | N-phenyltetrahydrophthalamic acid derivatives, methods of producing same, and herbicides containing same as effective components The invention provides N-phenyltetrahydrophthalamic acid derivatives represented by the general formula [I], methods of producing the same, herbicides containing the same as the effective components, imidoylchloride derivatives as the intermediate product... | 01/08/2002 |
| 6333082 | Liquid crystalline (E,E)-butadiene compounds and mixtures and devices containing such compounds Liquid crystalline compounds useful in super twisted nematic liquid crystal displays are described and have the formula: ##STR1## wherein n is 1-5; m is 0-5; p is 0, 1 or 2; q is 0, 1 or 2 p+q is less than or equal to 3; A1, A2, A3 | 12/25/2001 |
| 6303648 | Methods and compositions for the treatment and prevention of lung disease Methods and compositions for the treatment of lung disease, such as emphysema and/or bronchopulmonary dysplasia, in a mammal. Also disclosed are methods promoting the formation of alveolar septa and increasing the gas-exchange surface area of a mammalian ... | 10/16/2001 |
| 6255498 | Method for synthesizing diaryl-substituted heterocyclic compounds, including tetrahydrofurans A method is provided for synthesizing diaryl-substituted heterocyclic compounds, particularly 2,5-diaryl-substituted tetrahydrofurans and tetrahydrothiophenes. Methods for synthesizing starting materials and intermediates are provided as well. An importan... | 07/03/2001 |
| 6200353 | Coupler for use in oxidative hair dyeing Couplers for hair coloring compositions for oxidative dyeing of hair are compounds of the formula at least one coupler comprising a compound of the formula: ##STR1## wherein R is selected from the group consisting of C1 to C2 alkyl ... | 03/13/2001 |
| 6194599 | Process for preparing biaryl compounds The present invention provides a process for preparing biaryl compounds comprising reacting an arylzinc reagent with an arylchloride in the presence of a nickel catalyst or a palladium catalyst. The present invention specifically provides a process for th... | 02/27/2001 |
| 6153759 | Heterocyclic benzoyl intermediates for herbicidal compounds Heterocyclic substituted benzoyl derivatives of the formula ##STR1## where Z is a 5-membered or 6-membered heterocyclic, saturated or unsaturated radical containing one to three hetero atoms selected from the group consisting of oxygen, sulfur and ni... | 11/28/2000 |
| 6042620 | p-diaminobenzene derivative compounds and dye compositions containing same New p-diaminobenzene derivative compounds of the formula (I): ##STR1## and physiologically compatible water soluble salts thereof are described, wherein X represents oxygen, sulfur, selenium or N-R9, wherein R9 represents hydrogen, an alkyl group, a ... | 03/28/2000 |
| 6034273 | N-(arylmethylene)-1-chloro-1-(perfluoroalkyl) methylamine compounds There is provided a process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(arylmethylene)-1-chloro-1-(perfluoroalkyl)methylamine compounds. The 2-aryl-5-(perfluoroalkyl)pyrrole compounds are useful for the control of insect... | 03/07/2000 |
| 6001869 | Method of inhibiting parasitic activity A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myrist... | 12/14/1999 |
| 5972950 | 1,2-diarylmethylene derivatives, their methods of preparation and their uses in therapeutics The present invention relates to the derivatives of formula: ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.... | 10/26/1999 |
| 5929117 | Immunotherapeutic agents Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor , nuclear factor .kappa.B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory con... | 07/27/1999 |
| 5925631 | Alkylated styrenes as prodrugs to COX-2 inhibitors The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases c... | 07/20/1999 |
