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| Number | Title | Issue Date |
| 7432381 | 1,3-oxathiolane-2-thione compounds The present invention relates to 1,3-oxathiolane-2-thione compounds of the general formula (I): wherein R1 and R2 are the same or different, each of which denotes a straight-chain or branched alkoxy re... | 10/07/2008 |
| 7423170 | Anticancer agents based on regulation of protein prenylation Oncoproteins such as Ras and RhoB are known to induce cell division in an unrestrained manner when such proteins are localized at the inner surface of a cancer cell membrane. The localization is effected by the prenylation reaction, whereby a hydrophobic group (e.g.... | 09/09/2008 |
| 7390613 | Photoactive compounds The present application relates to a compound of formula Ai Xi Bi where Ai and Bi are each individually an organic onium cation; and Xi is anion of the formula −O3S—CF2CF2OCF2CF2—SO3 | 06/24/2008 |
| 7351841 | Heterocyclic compounds and thrombopoietin receptor activators A compound represented by the formula (1): wherein A is a nitrogen atom or CR4, B is an oxygen atom, a sulfur atom or NR9 (provided that when A is a nitrogen atom, B is not NH), R1 is a C | 04/01/2008 |
| 7300951 | Fluoro- and trifluoroalkyl-containing heterocyclic sulfonamide inhibitors of beta amyloid production and derivatives thereof Compounds of Formula (I), are provided where T is CHO, CON, or C(OH)R1R2; R1 and R2 are hydrogen, optionally substituted lower alkyl, CF3, optionally substit... | 11/27/2007 |
| 7288663 | Process for preparing linear organic oligomers The present invention relates to a process for preparing compounds of the formula (I), where n is an integer from 2 to 5, R1 is H or a C1-C20-alkyl group... | 10/30/2007 |
| 7262310 | Process for preparing 3-hydroxythiolane A process for preparing 3-hydroxythiolane which is characterized in reacting a compound of the following formula, wherein X is halogen atom, and R2 is substituted or unsubstituted alkyl group, substitu... | 08/28/2007 |
| 7206111 | Sterically hindered PI-bridge nonlinear optical chromophores, processes including same, and devices therefrom In various embodiments, chromophores are described that include novel electron acceptors, novel electron donors, and/or novel conjugated bridges that are useful in nonlinear optical applications. In some embodiments, the present invention provides chromophore archit... | 04/17/2007 |
| 7192535 | Conjugated molecule and electroluminescent device thereof and electronic device having the electroluminescent device It is intended to provide a novel material having no absorption or low absorption intensity in the visible region and to provide an electroluminescent device excellent in hole injection characteristic by using the novel material. A novel organic material wherein two... | 03/20/2007 |
| 7161013 | Terthiophene-3-carboxylic acid compound and fabricating method thereof, functionalized conductive terthiophene polymer with the compound as a monomer, process for DNA hybridization detection using the polymer, and fabricating method of probe DNA A novel terthiophene-3-carboxylic acid compound is disclosed that a functionalized conductive terthiophene polymer having carboxylic groups produced in an electrochemical method using the compound as a monomer and a novel process for detecting DNA hybridization thro... | 01/09/2007 |
| 7144897 | Hydroxy alkyl amines Disclosed are compounds of formula X, which are useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions comprising compounds of formula X and methods of preparing the compou... | 12/05/2006 |
| 7125907 | Thiolactones This invention provides new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, inhibiting angiogen... | 10/24/2006 |
| 7109355 | Fluorinated π-bridge second order nonlinear optical chromophores and electro-optic devices therefrom A nonlinear optical chromophore having the formula D-π-A, wherein π is a π bridge including a thiophene ring having oxygen atoms bonded directly to the 3 and 4 positions of the thiophene ring, D is a donor, A is an acceptor, and the oxygen atoms are further subst... | 09/19/2006 |
| 7101904 | Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents A compound or a pharmaceutically acceptable salt or a prodrug thereof, wherein A, B, R1, R2, D, and E are defined herein. Use of the diseases for the treatment of diseases, and compositions ... | 09/05/2006 |
| 7102016 | Preparation of 2,2′-di(3,4-ethylenedioxythiophene)s The invention relates to a process for preparing compounds of the general formula (I) to novel compounds of this substance class and also to their use as important precursors or for preparing important precursors... | 09/05/2006 |
| 7060858 | Method for manufacturing sulfonium salts It is an object of the invention to provide a method which makes it possible to manufacture the desired sulfonium salts directly without using a metathesis process and without using acids in large excess amounts. An aryl compound (A) in which a hydrogen atom is bond... | 06/13/2006 |
| 7057038 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer... | 06/06/2006 |
| 7029606 | Hyperpolarizable organic chromophores A dihydrofuran-containing nonlinear optical chromophore having a π-electron donor group conjugated to the dihydrofuran group through a π-electron conjugated bridge group. The nonlinear optical chromophore is a hyperpolarizable chromophore that can be used as an el... | 04/18/2006 |
| 7019453 | Polymers having pendant nonlinear optical chromophores and electro-optic devices therefrom A nonlinear optical chromophore having the formula D-π-A, wherein π is a π bridge including a thiophene ring having oxygen atoms bonded directly to the 3 and 4 positions of the thiophene ring, D is a donor, and A is an acceptor. ... | 03/28/2006 |
| 7014796 | Nonlinear optical compounds and methods for their preparation Nonlinear optically active compounds, methods for making nonlinear optically active compounds, compounds useful for making nonlinear optically active compounds, methods for making compounds useful for making nonlinear optically active compounds, macrostructures that... | 03/21/2006 |
| 6995884 | Fluorinated crosslinked electro-optic materials and electro-optic devices therefrom A nonlinear optical chromophore having the formula D-π-A, wherein π is a π bridge including a thiophene ring having oxygen atoms bonded directly to the 3 and 4 positions of the thiophene ring, D is a donor, and A is an acceptor. ... | 02/07/2006 |
| 6949536 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents This invention provides a compound of the formula: or its pharmaceutically acceptable salt thereof, wherein A is partially unsaturated or unsaturated five membered heterocyclic, or partially unsaturated or unsaturated ... | 09/27/2005 |
| 6890715 | Sensors of conducting and insulating composites The present invention provides a class of sensors prepared from at least a first material having a positive temperature coefficient of resistance and a second non-conductive or insulating material compositionally different than the first material that show an increa... | 05/10/2005 |
| 6840965 | P-aminophenols and colorants containing said compounds The object of the invention are p-aminophenol derivatives of general formula (I) or physiologically tolerated, water-soluble salts thereof and oxidative coloring preparations based on a developer-coupler combination co... | 01/11/2005 |
| 6734207 | Cytotoxic compounds Compounds are described that bind to tubulin causing tubulin depolymerization and inhibiting tubulin polymerization. The compounds of the invention are therapeutically effective to inhibit cellular proliferation, for example, as effective anti-cancer agents. The com... | 05/11/2004 |
| 6727238 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents This invention provides a compound of the formula: or its pharmaceutically acceptable salt thereof, wherein A is partially unsaturated or unsaturated five membered heterocyclic, or partially unsaturated or unsaturated fi... | 04/27/2004 |
| 6716995 | Design and synthesis of advanced NLO materials for electro-optic applications In various embodiments, chromophores are described that include novel electron acceptors, novel electron donors, and/or novel conjugated bridges that are useful in nonlinear optical applications. In some embodiments, the present invention provides chromophore archit... | 04/06/2004 |
| 6706725 | Vitamin D analogues The invention relates to novel bicyclic compounds having the general formula (I): as well as to a method for preparing them and to their use in pharmaceutical compositions intended for use in human or veterinary medicine... | 03/16/2004 |
| 6686478 | Thienylsulphonylamino(thio)carbonyl compounds The invention relates to novel thienylsulphonylamino(thio)carbonyl compounds of the formula (I), ##STR1## in which Q represents oxygen or sulphur, R1 represents cyano, halogen or in each case optionally cyano-, halogen- or C1 -C... | 02/03/2004 |
| 6589976 | Utilizing spirocyclic phenyl keto-enols as pesticides and herbicides The invention relates to novel spirocyclic phenylketoenols of the formula ##STR1## in which Het represents one of the groups ##STR2## in which Q represents ##STR3## and X, Y, Z, m, n, R6, R9, R10 and R11 are ea... | 07/08/2003 |
| 6566375 | Elevation of HDL cholesterol by 4-[(aminothioxomethyl)-hydrazono]-N-(substituted)-4-arylbutanamides Compounds of this invention increase plasma levels of high density lipoprotein or HDL, the "good" cholesterol and as such may be useful for treating diseases such as atherosclerosis. These compounds are represented by the formula ##STR1## wherein: R | 05/20/2003 |
| 6555542 | Sulfonamide lactam inhibitors of FXa and method Sulfonamide lactams of the following formula ##STR1## wherein X, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R7 and R8 are as described herein, ... | 04/29/2003 |
| 6506780 | Benzophenones and sulfones as inhibitors of glycine uptake This invention relates to a series of substituted benzophenone and sulfone compounds of the formula I ##STR1## wherein ring A, Z, Y, R and X are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmaceutically... | 01/14/2003 |
| 6465060 | Tetrahydrothiophene derivatives, and their use in liquid-crystalline mixtures Tetrahydrothiophene derivatives of the formula (I) R1 --X--(A1 --M1)a --(A2 --M2)b --A3 --Y--T--Z--R2 (I) where the symbols and indices have the following meanings, ... | 10/15/2002 |
| 6441010 | Bi-aromatic compounds linked via a heteroethynylene radical, and pharmaceutical and cosmetic compositions containing them Bi-aromatic compounds linked via a heteroethynylene radical are provided along with pharmaceutical and cosmetic compositions containing these compounds and methods for their use.... | 08/27/2002 |
| 6441177 | Tertiary amines Tertiary amines of the formula ##STR1## wherein A1, A2, A3, A4, M, p, T and Q are as defined herein, and acid addition salts thereof, have antimycotic and cholesterol-lowering activity.... | 08/27/2002 |
| 6410748 | Alicycli c group-containing monomer A monomer represented by the following general formula (m-1): ##STR1## wherein R is a group having an alicyclic skeleton, R2 s may be the same or different and are individually hydrogen atom, halogen atom or monovalent organic group, X1 | 06/25/2002 |
| 6376502 | Osteoporosis compounds This invention relates to prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for t... | 04/23/2002 |
| 6376682 | Compound with -glucosidase inhibiting action and method for producing the same A compound expressed by chemical structural formula: ##STR1## having the characteristic of specifically inhibiting the activity of -glucosidase (an enzyme that breaks down disaccharides, etc.) at the intestinal level. The compound is obtained by ex... | 04/23/2002 |
| 6369239 | Process for the preparation of dialkylthiophenes and alkylenedioxythiophenes A process for the preparation of dialkoxythiophenes and alkylene-dioxythiophenes in high purity and very good yields by decarboxylation of dialkoxythiophene-dicarboxylic acids or alkylenedioxythiophenedicarboxylic acids, respectively, in solvents that ... | 04/09/2002 |
