Class 549/6 - The hetero ring is five-membered

Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the hetero ring is five-membered.
No. of patents: 215
Last issue date: 07/27/2010

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Number	Title	Issue Date
7763739	Cycloolefin phosphine ligands and their use in catalysis The present invention concerns novel bidentante optionally N-containing P-ligands of general formula (I) embracing a two-ring-system and processes for synthesizing them, transition metal complexes of these compounds and the...	07/27/2010
7368597	Carbonylation process using metal-polydentate ligand catalysts A process for the liquid phase carbonylation of an alcohol and/or a reactive derivative thereof in the presence of hydrogen in which there is employed a catalyst comprising rhodium of iridium coordinated with a polydentate ligand. ...	05/06/2008
7307037	Metallic catalysts for chemo-, regio- and stereoselective reactions, and corresponding precursors Metallic catalysts of the general formula (I) and their precursors, suitable for chemo- regio- and stereoselective reactions, derived from ortho-bis-(1-phospholanyl)-heteroarenes. The new catalysts are characterized by the presence of two homo-morphic phospholanic r...	12/11/2007
7276626	Carbonylation process using metal-tridentate ligand catalysts A process for the production of a carboxylic acid and/or the alcohol ester of a carboxylic acid by carbonylating an alcohol and/or a reactive derivative thereof with carbon monoxide employing as the carbonylation catalyst, cobalt, rhodium or iridium coordinated with...	10/02/2007
7169766	Methods and compositions for treating hepatitis C virus A method and composition for treating a host infected with hepatitis C comprising administering an effective hepatitis C treatment amount of a described 1′, 2′ or 3′-modified nucleoside or a pharmaceutically acceptable salt or prodrug thereof, is provided....	01/30/2007
7166726	Aryl substituted 3,4-dihydroanthracene derivatives having retinoid antagonist or retinoid inverse agonist type biological activity Disclosed herein are compounds of the formula wherein R1 is independently H or alkyl of 1 to 6 carbons; R2 is optional and is defined as lower alkyl of 1 to 6 carbons, F, Cl, Br...	01/23/2007
7135583	Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters A novel process for preparation of alkenylphosphine oxides or alkenylphosphinic acid esters provided by which the objective compounds can be easily, safely and efficiently synthesized and easily separated and purified with little formation of by-products. Specifical...	11/14/2006
7118731	Drugs for the diagnosis of tissue reproductive activity or the treatment of proliferative diseases An agent which comprises, as an active ingredient, a radiolabeled compound as represented by the following formula or a pharmaceutically acceptable salt thereof: wherein R1 denotes hydrogen, or a linea...	10/10/2006
7115654	Caspase-1 inhibitors and methods for their use The invention provides compounds of Formula I and derivatives thereof, pharmaceutical compositions comprising a compound of Formula I, and methods of treatment utilizing such compounds and compositions:	10/03/2006
7094907	Ligands for asymmetric reactions The invention relates to a process for the manufacture of bidentate ligands of the formula IA and IIA, characterized in that N,N-(optionally substituted)dialkylamino phosphines bound to an aromatic carbon are lithiated in ortho-position and the lithiated compounds a...	08/22/2006
7081533	Cycloaliphatic/aromatic diphosphines and use thereof in catalysis The present invention concerns novel unsymmetrical chiral diphosphines of a mixed aliphatic-aromatic type and processes for synthesizing them, complexes of these compounds and their use as catalysts. ...	07/25/2006
7076115	Analysis of chemical data from images Computer programs and computer-implemented methods implement techniques for evaluating experimental data from a library of materials. The techniques receive a plurality of images of a library of materials that includes an array of members associated with locations i...	07/11/2006
7074432	Method of modifying the release profile of sustained release compositions The present invention relates to a method for the sustained release in vivo of a biologically active agent comprising administering to a subject in need of treatment an effective amount of a sustained release composition comprising a biocompatible polymer having the...	07/11/2006
7045115	Drugs for the diagnosis of tissue-reproductive activity or the treatment of proliferative diseases An agent which comprises, as an active ingredient, a radiolabeled compound as represented by the following formula or a pharmaceutically acceptable salt thereof: wherein R1 denotes hydrogen, or a linea...	05/16/2006
7030103	Sulfonamidomethyl phosphonate inhibitors of β-lactamase The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural product and...	04/18/2006
7019024	Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ...	03/28/2006
6921756	Inhibitors of β-lactamase The invention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural product and...	07/26/2005
6921774	Compounds and their use as glycine transport inhibitors The invention provides novel compounds of the formula I below: wherein the meaning of each substituent is defined in the application. The compounds are useful as inhibitors of the glycine transporter and useful in the ...	07/26/2005
6919322	Phenyl Phosphonate Fructose-1,6-Bisphosphatase Inhibitors Novel FBPase inhibitors of the formula I are useful in the treatment of diabetes and other conditions associated with elevated blood glucose. ...	07/19/2005
6908722	Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition A novel photoacid generator containing a structure of the following formula (I), wherein R is a monovalent organic group with a fluorine content of 50 wt % or less, a nitro group, a cyano group, or a hydrogen atom, and...	06/21/2005
6703371	Preparations for reducing oxygen consumption during physical efforts The invention relates to pharmaceutically active substances from the group comprising midazolam and compounds with a methyl-substituted nitrogen atom that is the ring atom of a nitrogenous heterocycle. These substances are used to reduce the oxygen consum...	03/09/2004
6696081	Carbohydrate based lipid compositions and supramolecular structures comprising same Novel lipid compounds and compositions comprising carbohydrate backbones are used to make supramolecular structures such as vesicles, liposomes (single lamellar, multilamellar, and giant), micelles, hexagonal phases, microemulsions and others. The novel c...	02/24/2004
6613945	Resolution method for a racemic mixture of aldehydes The invention concerns a resolution method for a racemic mixture of aldehyde of formula (I). ##STR1## The aldehydes of formula I are useful in their enantiomeric form or their racemic form for preparing transition metal complexes useful as catalysts ...	09/02/2003
6576772	Chiral phosphines, transition metal complexes thereof and uses thereof in asymmetric reactions Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include (R,S,S,R)-DIOP*. The ruthenium complex reduces enamide to the corresponding amine with up to 99% enantiosel...	06/10/2003
6573389	Bidentate organophosphorous ligands and their use The present invention relates to unsymmetric bidendate organophosphorus ligands of the formula (I) which have a modular structure and have a trivalent phosphine function and a second trivalent phosphorus group which is bound via a heteroatom to a chiral l...	06/03/2003
6521605	Amidophosphate derivatives The present invention provides amidophosphate derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders....	02/18/2003
6500811	Sulfonylaminophosphinic and sulfonylaminophosphonic acid derivatives, methods for their preparation and use Compounds of the formula I ##STR1## are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading enzymes is involved....	12/31/2002
6485886	Oxime derivatives and the use thereof as latent acids New oxime derivatives of formula (I) or. (II), wherein m is 0 or 1; R1 inter alia is phenyl, naphthyl, anthracyl, phenanthryl or a heteroaryl radical; R'1 is for example C2 -C12 alkylene, phenylene, naphthylene;...	11/26/2002
6482958	Methods for the preparation of 4-hydroxy benzothiophene The present invention is concerned with a novel process for the preparation of a hydroxybenzothiophene that is an intermediate for synthesizing pharmaceutically active substances, e.g. 5-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-7-benzothiophenylmethyl]...	11/19/2002
6479471	NAALADase inhibitors The present disclosure relates to dipeptidase inhibitors, and more particularly, to novel phosphonate derivatives, hydroxyphosphinyl derivatives, and phosphoramidate derivatives that inhibit N-Acetylated ଱-Linked Acidic Dipeptidase (NAALADase) enzym...	11/12/2002
6472406	Sulfonamidomethyl phosphonate inhibitors of beta-lactamase The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel ଲ-lactamase inhibitors, which are structurally unrelated to the nat...	10/29/2002
6451845	Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia This invention provides compounds of Formula I having the structure ##STR1## wherein R1 and R2 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, halogen, perfluoroalkyl of 1-6 carbon atoms, cycloalkyl of 3-8 carbon atoms,...	09/17/2002
6355810	Multibinding inhibitors of HMG-CoA reductase Disclosed are multibinding compounds which inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-COA reductase), the rate limiting enzyme in cholesterol biosynthesis. The multibinding compounds of this invention containing from 2 to 10 ligands cova...	03/12/2002
6339161	Group 8, 9 or 10 transition metal catalyst for olefin polymerization Olefin co- or homopolymers having a good molecular weight and short chain branching may be prepared in the presence of a tridentate complex of a Group 8, 9 or 10 metal....	01/15/2002
6329421	Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of ...	12/11/2001
6313159	Metabotropic glutamate receptor ligand derivatives as naaladase inhibitors The present invention relates to metabotropic glutamate receptor ligand derivatives and methods of using the same to inhibit NAALADase enzyme activity, to effect neuronal activities, to inhibit angiogenesis, and to treat glutamate abnormalities, compulsiv...	11/06/2001
6307083	Specific silane compounds, method of synthesizing them, luminescent device materials comprising them, and luminescent devices containing such materials Silane compounds represented by formula (1), a synthesis method thereof, luminescent device materials comprising such silane compounds, and luminescent devices containing such materials: ##STR1## wherein each of R1 and R2 groups repr...	10/23/2001
6281238	4-aryl-1-oxa-9-thia-cylopenta[B]fluorenes This invention provides compounds of Formula I having the structure ##STR1## wherein B and D are each, independently, hydrogen, halogen, --CN, alkyl of 1-6 carbon atoms, aryl, or aralkyl of 6-12 carbon atoms; R1 is hydrogen, alkyl of 1-6 carbon atom...	08/28/2001
6277833	Substituted triols Substituted triols are prepared by reducing appropriately substituted carboxylic esters. The substituted triols can be used as active substances in medicaments....	08/21/2001
6235920	Method for preparing functional halosilanes The present invention relates to a method for preparing a functional halosilanes by reacting A) a cyclic silyl ether having the formula ##STR1## wherein each R is independently selected from a hydrocarbyl group or a halogen-substituted hydrocarbyl group ...	05/22/2001

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Class 549/6 - The hetero ring is five-membered