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Class 549/552 - Cyano or nitrogen and the hetero ring bonded directly to the same carbon


Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein cyano (i.e., -C=N) or nitrogen
No. of patents: 89
Last issue date: 12/13/2011


1      
NumberTitleIssue Date
8076495Process for the preparation of aromatic N-gylcidyl amines
A process for the preparation of aromatic N-glycidylamines is described, wherein an amine which contains at least one aromatic aminehydrogen atom is heated with at least 0.7 equivalent of epichlorohydrin per aminehydrogen equivalent of the aromatic amine, using a di...
12/13/2011
7462728Diepoxide derivatives of N,N*-disubstituted disulfonamides
The present invention relates to novel diepoxides having the formulas I. and II. R*N(A)SO2RSO2N(A)R*  I R*SO2N(A)RN(A)SO2R*  II where A=2,3-epoxypropyl, R* is a monovalent hydrocarbon ...
12/09/2008
7408008Method of producing highly functionalized 1,3-diamino-propan-2-ols from solid support
The invention is directed to compounds and methods of synthesizing hydroxyethlamino amides and their use in treatment of aspartyl protease mediated diseases and conditions. ...
08/05/2008
7300986Polyepoxy compounds having an amide linkage
The present invention provides compounds that have an amide linkage and at least two epoxy groups. The compounds are preferably aliphatic. ...
11/27/2007
7220870Hydrolytic kinetic resolution of cyclic substrates
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisome...
05/22/2007
6849750Processes and intermediates for preparing benzyl epoxides
Disclosed are intermediates and processes for preparing epoxides of the formula: where R and PROT are defined herein. These epoxides are useful as intermediates in the production of biologically active compounds, i.e.,...
02/01/2005
6818727Highly purified epoxy resin
Provided is an epoxy resin having glycidylamino group, wherein the content of hydrolyzable chlorine is 1000 ppm or less. The epoxy resin is useful for adhesives, paints and electric/electronic materials(e.g. insulation materials, laminated plate, etc.). ...
11/16/2004
6570027Method of preparing intermediates useful in synthesis of retroviral protease inhibitors
A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde....
05/27/2003
6278002Process for the preparation of (2r,3s)-3-amino-1,2-oxirane
A process for producing (2R,3S)-3-amino-4-phenylbutane-1,2-epoxide compounds which comprises treating a (2S,3S)-3-amino-1-halo-2-hydroxy-4-phenylbutane compound or a (2S,3S)-3-amino-4-phenylbutane-1,2-epoxide with a carboxylic acid quaternary ammoniu...
08/21/2001
6153771Intermediates for the preparation of iodinated contrast agents
5-Substituted isophthalic acid bis(allylamides) and bis(allylamide epoxides) in which said 5-substituent is --NO2, --NH2, --NHR1 or --NR1 R2 where R1 and R2 are independently opt...
11/28/2000
6127556Epoxide formation by continuous in-situ synthesis process
In a method of preparing an aminoepoxide wherein a protected aminoaldehyde is reacted with a halomethyl organometallic reagent in an appropriate solvent at a temperature above -80° C., wherein said halomethyl organometallic reagent is formed by reaction ...
10/03/2000
5998330UV stable microbial insecticides, methods of making, methods of using
A method of treating vegetation by application of a microbial insecticide in which a quinone has been covalently bonded to the viral occlusion body surface of the microbial insecticide in order to improve the UV stability of the microbial insecticide by f...
12/07/1999
5962683Oxazoline compounds as stabilizers
A description is given of compounds of the formula I ##STR1## where r is 0 or 1 and y is a number from the range 1-3; X is a direct bond or --NR8 --, --CO--, --CONH-- or --COO-- or a divalent aliphatic or mixed aromatic-aliphatic C1
10/05/1999
5962704Production of amide derivatives and intermediate compounds therefor
A method for producing an amide derivative of the formula ›XV! ##STR1## wherein each symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing said compound and a production method thereof. The p...
10/05/1999
5883121Epoxysuccinamide derivative or salt thereof, and medicine comprising the same
The invention relates an epoxysuccinamide derivative represented by the general formula (1) ##STR1## wherein R1 and R2 are the same or different from each other and independently represent H or an aromatic hydrocarbon group or a...
03/16/1999
5883264Process for preparing optically active trans-3-phenylglycidamide compounds
Process for preparing optically active trans-3-phenylglycidamide compound, which comprises subjecting racemic trans-3-phenylglycidamide compound of the formula (I) ##STR1## wherein Ring A is substituted or unsubstituted benzene, and R1 is ...
03/16/1999
5854303Polymer, article and method for inhibiting the growth of ocular pathogens in eye care products
A polymeric material incorporating a polyvalent cation chelating agent in an amount effective to inhibit the growth of an ocular pathogen, particularly a protozoan, can be used to produce eye care products such as contact lens cases and containers for con...
12/29/1998
5773468Irreversible HIV protease inhibitor having an anti-aids activity and process for the preparation thereof
The present invention relates to a novel compound of formula (I) and pharmaceutically acceptable salts, hydrates and solvates thereof which is an irreversible HIV protease inhibitor; a process for the preparation thereof; and a pharmaceutical composition ...
06/30/1998
5763631Irreversible HIV protease inhibitors, intermediates, compositions and processes for the preparation thereof
Cis-epoxide compounds of formula (I-3) and pharmaceutically acceptable salts, hydrates and solvates thereof: ##STR1## wherein: R1 is a cycloalkyl, or arly-substituted lower alkyl group; K and J are independently a group having the formula of ...
06/09/1998
5739178Polymer, article and method for inhibiting the growth of ocular pathogens in eye care products
A polymeric material incorporating a polyvalent cation chelating agent in an amount effective to inhibit the growth of an ocular pathogen, particularly a protozoan, can be used to produce eye care products such as contact lens cases and containers for con...
04/14/1998
5717054Epoxy resins consisting of flexible chains terminated with glycidyloxyphenyl groups for use in microelectronics adhesives
This invention relates to flexible epoxy resins that have a structural composition comprising an oligomeric backbone of alkylene or alkyleneoxy repeat units, terminated with an aromatic moiety bearing one or more epoxy functionalities....
02/10/1998
5693847Heteroatom functionalized ଱-methyl ketones
The present invention relates to functionalized ketones and novel processes for synthesizing those ketones. The processes of this invention are especially well suited for synthesizing ଱-methyl leaving group functionalized ketones. This invention als...
12/02/1997
5679687Irreversible HIV protease inhibitors, compositions containing same and process for the preparation thereof
The present invention relates to novel compounds of formula (I) which have inhibitory activity against human immunodeficiency virus ("HIV") protease, a process for the preparation thereof, and compositions for prevention or treatment of AIDS by HIV infect...
10/21/1997
5670675Retroviral protease inhibiting compounds
A retroviral protease inhibiting compound of the formula A-X-B or a pharmaceutically acceptable salt, prodrug or ester thereof, wherein X is a linking group; A is (1) substituted amino, (2) substituted carbonyl, (3) functionalized imino, (4) functionalized alkyl, (...
09/23/1997
5670517Irreversible HIV protease inhibitors, compositions containing same and process for the preparation thereof
The present invention relates to novel compounds of formula (I) which has inhibitory activities against human immunodeficiency virus ("HIV") protease, a process for the preparation thereof, and compositions for prevention or treatment of AIDS by HIV infec...
09/23/1997
5668227Cyclohexyl-group-containing glycidyl ethers
Novel cyclohexyl-group-containing glycidyl ethers of formulae I to IV according to claim 1, which are distinguished especially by a low chlorine content and a low viscosity and which can be used, for example, in epoxy resin formulations as reactive diluen...
09/16/1997
5650412HIV protease inhibitors useful for the treatment of AIDS
Compounds of formula ##STR1## are HIV protease inhibitors. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ...
07/22/1997
5618939Process for making HIV protease inhibitors
A process is disclosed for making a chiral compound of the formula ##STR1## comprising reacting an epoxide compound of the formula ##STR2## and an amide of the formula ##STR3## in the presence of a strong base at a low temperature....
04/08/1997
56123392-Hydroxy-3-aminopropylsulfonamides
2-Hydroxy-3-aminopropylsulfonamides are provided along with methods for synthesizing and using such compounds, and chemical intermediates employed in the synthetic methods....
03/18/1997
5563168O-Benzyloxime ethers and crop protection agents containing these compounds
O-Benzyloxime ethers of the formula I ##STR1## where 5 X is substituted or unsubstituted CH2, NOalkyl Y is O, S, NR5 R1, R2, R5 are H, alkyl Z1, Z2 are H, halogen, methyl, methoxy, cy...
10/08/1996
5552558Retroviral protease inhibiting compounds
A retroviral protease inhibiting compound of the formula: ##STR1## is disclosed....
09/03/1996
5543433Azine-substituted phenylacetic acid derivatives and fungicides containing these
Compounds of the formula I ##STR1## where X is hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, cyano or nitro, Y is an amino, methylamino or dimethylamino group, Z is a group CHCH3, CHOCH3 or NOCH3, R is hydrogen or alk...
08/06/1996
5508430Oxirane intermediates for novel alcohols
Novel alcohols of the formula ##STR1## wherein Ra is azido or phthalimido, R4 is alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, R7 and R8 together are a trimethylene or tetramethylene group which is o...
04/16/1996
5391552Diphenylpiperazine derivative and drug for circulatory organ containing the same
A diphenylpiperazine derivative represented by general formula (1), salt thereof, and drug for the circulatory organs containing the same as the active ingredient: ##STR1## wherein R1 and R2 may be the same or different from eac...
02/21/1995
5362849N-glycidyl compound
The new compound N,N,N'N'-tetraglycidyl-3,3'-diethyl-4,4'-diaminodiphenylmethane and curable resin compositions containing it....
11/08/1994
5360884Mesogenic glycidyl amine blends
Glycidyl amines containing mesogenic moieties result in improved properties when cured. These amines are useful in coatings, adhesives, encapsulants, moldings, laminates, and the like....
11/01/1994
5310956Optically active epoxides and a process for the production thereof
The present invention is optically active epoxides and its production characterized in that the process comprises reacting alkenyl ethylene glycols with 0.5 to 2.0 equivalents of a titanium-tetraalkoxyde, a peroxide and an L-(+)- or D-(-)-dialkyl tartrate...
05/10/1994
5283270Glycidyl diamines containing aromatic trifluoromethyl group and epoxy resins prepared therefrom
Disclosed are glycidyl diamines having the formulas ##STR1## where n is 1 or 2, m is 0, 1, or 2, X is Y or ##STR2## and Y is --, O, S, SO, SO2, CO, C(CH3)2, or C(CF3)2. An epoxy resin can be...
02/01/1994
5280069N-glycidyl compound
The new compound N,N,N'N'-tetraglycidyl-3,3'-diethyl-4,4'-diaminodiphenylmethane and curable resin compositions containing it....
01/18/1994
5266365Epoxy polymeric nonlinear optical materials
The present invention is directed to an epoxy-containing polymeric material having nonlinear optical properties, particularly a glycidyl amine polymer, and a process for making the nonlinear optical (NLO) epoxy-containing polymeric material including poli...
11/30/1993
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