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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 7332616 | Polymerizable compound, polymer, positive-resist composition, and patterning process using the same The present invention provides a polymer which has at least one or more of a repeating unit represented by a following general formula (1a), a repeating unit represented by a following general formula (2a) and a repeating unit represented by a followin... | 02/19/2008 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 6864254 | Inhibitor for 20-hete-yielding enzyme An inhibitor for 20-hydroxyeicosatetraenoic acid production which comprises as the active ingredient a specific hydroxyformamidine derivative or a pharmacologically acceptable salt thereof. It is useful especially as a remedy for kidney diseases, cerebrovascular dis... | 03/08/2005 |
| 6514967 | Compound for preparing medicines for treating pathologies involving extracellular glutamate, and methods for obtaining same The invention relates to compounds of the following general formula (I): ##STR1## in which: R1 and R2 represent a hydrogen atom, or form a ring, especially a benzene ring, R3 represents a hydrogen atom or an alkyl group, e... | 02/04/2003 |
| 6479514 | Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity Compounds of formula (I) in which the substituents and symbols have the meanings indicated in the description, are suitable for the control of Helicobacter bacteria. ##STR1##... | 11/12/2002 |
| 6391912 | Substituted phenylketoenols The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which Het represents one of the groups ##STR2## and G, V, W, X, Y and Z are each as defined in the description, to processes and intermediates for their prep... | 05/21/2002 |
| 6302837 | Benzothiophene, benzofuran and indole compounds A compound selected from those of formula (I): ##STR1## wherein: X represents oxygen, sulphur, or NR3 wherein R3 is as defined in the description, Y represents oxygen, sulphur, NR3, or may represent single bond in certain ... | 10/16/2001 |
| 6288107 | Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same Novel sulfatase inhibitor/estrogen receptor blocker compounds useful in the treatment of estrogen dependent illnesses are disclosed. The compounds generally comprise a sulfamate moiety and an aromatic, estrogen receptor blocker moiety. Methods for synthes... | 09/11/2001 |
| 6281240 | Diarylsulfonylureas for use in treating secretory diarrhea This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea. This invention also describes specific diarylsulfonylureas f... | 08/28/2001 |
| 6169087 | Modulators of protein tyrosine phosphatases (PTPases) The present invention provides novel compounds of Formula 1 or Formula 2 and compositions thereof, methods of their use, and methods of their manufacture, ##STR1## wherein X, Y, Z, W, R1, R2 and R3 are defined more fully i... | 01/02/2001 |
| 6100292 | Ketone derivatives and their medical applications This invention relates to ketones represented by the following formula ##STR1## and to drugs in which such a ketone or pharmacologically acceptable salt thereof is an effective component. The ketones of the present invention encourage the production of pl... | 08/08/2000 |
| 6048875 | Benzothiophene, benzofuran and indole compounds A compound of formula (I): ##STR1## wherein: X represents oxygen, sulphur, or NR3 wherein R3 is as defined in the description, Y represents oxygen, sulphur, NR3, or may a single bond when X represents NR3, ... | 04/11/2000 |
| 6040309 | Benzothiophene derivatives useful in therapy Compounds of formula I, ##STR1## wherein X represents O or S(O)m ; R1 and R2 independently represent phenyl, naphthyl or heteroaryl; each of which is optionally fused and optionally substituted; Y represents a bond, O, (CH... | 03/21/2000 |
| 5989451 | Compounds and methods for doping liquid crystal hosts This invention provides chiral thioindigo compounds for doping smectic liquid crystal hosts, wherein the compounds modulate a chiral bulk property of an induced chiral smectic liquid crystal phase upon irradiation at a wavelength in the visible range. Mod... | 11/23/1999 |
| 5986109 | Benzothiophene compounds, intermediates, compositions, and methods A compound of fomula XIV: ##STR1## wherein: R1a is --H or --OR7a in which R7a is a hydoxy protecting group; R2a is --H, halo, or OR8a in which R8a is a hydroxy protecting group; and R | 11/16/1999 |
| 5981765 | Benzothiophene compounds, intermediates, compositions, and methods The present invention provides a compound of formula ##STR1## wherein R1a is --H or --OR7a in which R7a is a hydroxy protecting group; R2a is --H, halo, or --OR8a in which R8a is a hydroxy ... | 11/09/1999 |
| 5977382 | Benzo[b]thiophene compounds, intermediates, processes, compositions, and methods The instant invention provides novel benzo[b]thiophene compounds, intermediates, compositions, pharmaceutical formulations, and methods of use.... | 11/02/1999 |
| 5977098 | Benzo[B]thiophene compounds, intermediates, processes, compositions, and methods The invention provides a compound of formula I: ##STR1## or a pharmaceutically acceptable salt or solvate thereof; pharmaceutical formulations containing a compound of formula I, and methods of using a compound of formula I for the inhibition of bone... | 11/02/1999 |
| 5863936 | Telomerase inhibitors Methods and compositions for treating cancer and other diseases in which inhibition of telomerase activity can ameliorate disease symptoms or prevent or treat the disease relate to compounds characterized by the following structure: ##STR1## and... | 01/26/1999 |
| 5843965 | Benzo B! thiophene compounds, intermediates, processes, compositions, and methods The instant invention provides novel benzob!thiophene compounds, intermediates, compositions, pharmaceutical formulations, and methods of use for the inhibition of bone loss or bone resorption and for treatment of cardiovascular-related pathological con... | 12/01/1998 |
| 5789436 | 4,6 Di-t-butyl-5-hydroxy-2,3-dihydrobenzothiophene A compound represented by formula (I): ##STR1## wherein R1 represents a hydrogen atom, a lower alkyl group or an acyl group; R2 and R3, which may be the same or different, each represents a hydrogen atom, an optionall... | 08/04/1998 |
| 5780648 | Benzothiophene compounds, and uses formulations thereof Benzothiophenes, and uses and formulations thereof, are provided by the present invention.... | 07/14/1998 |
| 5739296 | Method and materials for thermostable and lightfast dichroic light polarizers Polarizing coatings are formed from dyestuffs which provide a stable liquid crystalline phase in a wide range of concentrations, temperatures and pH-values. Particles formed by aggregates of the liquid crystal molecules are oriented in a predetermined dir... | 04/14/1998 |
| 5719287 | Intermediates for inhibitors of HIV protease and method of preparation thereof The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of their use.... | 02/17/1998 |
| 5684033 | Non-peptide tachykinin receptor antagonists This invention provides a novel series of non-peptidyl compounds which are useful in the treatment or prevention of a physiological disorder associated with an excess of tachykinins. This invention also provides methods for the treatment of such physiolog... | 11/04/1997 |
| 5663375 | Pharmaceutical compounds Pharmaceutical compounds of the formula ##STR1## in which n is 0, 1 or 2 and R1 is attached at any of the positions 7, 8, 9 or 10, and each R1 is halo, carboxy, trifluoromethyl, hydroxy, C1-4 alkyl, C1-4 al... | 09/02/1997 |
| 5635527 | Carboxylic acid compound having condensed ring, salt thereof and pharmaceutical use thereof A novel carboxylic acid compound having a condensed ring, which is represented by the formula (I) ##STR1## wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition thereof ... | 06/03/1997 |
| 5608074 | Process for the synthesis of 5-amino tetrazole derivatives An improved process for the preparation of 3-chlorobenzo[b]thiophene-2-carbonyl chlorides is described where a cinnamic acid is converted in the presence of thionyl chloride and a 4-N,N'-disubstituted aminopyridine in one step to the desired product.... | 03/04/1997 |
| 5569772 | Process for the synthesis of benzo[b]thiophenes The present invention is directed to a new process for the synthesis of 2-aryl benzo[b]thiophenes, and to novel intermediates therefor.... | 10/29/1996 |
| 5532254 | Modulation of calcium channels using benzothiophenes A method for modulating calcium channels, increasing the density of calcium channels in vascular and cardiac tissue with no changes in inotropic or pressor response, comprising administering to a warm-blooded animal in need thereof a pharmaceutically-effe... | 07/02/1996 |
| 5498630 | Fungicides for the control of take-all disease of plants A method of controlling Take-All disease of plants by applying a fungicide of the formula ##STR1## wherein Z1 and Z2 are C and are part of an aromatic ring which is benzothiophene; and A is selected from --C(X)-amine wherein the amine is an unsubstit... | 03/12/1996 |
| 5407901 | Herbicidal oxatricyclic ethers This patent application relates to Certain tricyclic ether herbicidal compounds and their use to control a broad spectrum of undesirable plant growth.... | 04/18/1995 |
| 5378699 | Methods of using dihydropyrans Methods of treating an immune disease, cell proliferation, restenosis and vascular smooth muscle cells using the pharmaceutical compounds of the formula ##STR1## in which R2 is phenyl, naphthyl or heteroaryl selected from thienyl, pyr... | 01/03/1995 |
| 5356926 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo [ଲ]thiophene-2-carboxamides as inhibitors of cell adhesion 3-Alkyloxy-, aryloxy-, or arylalkyloxybenzo[b]-thiophene-2-carboxamides are described as agents which block leukocyte adherence to vascular endothelium and, as such, are effective therapeutic agents for treating inflammatory diseases. Certain of these com... | 10/18/1994 |
| 5338735 | Pharmaceutical compounds Compounds of the formula: ##STR1## in which each R1 is hydrogen, C1-4 alkyl, C1-4 alkoxy, halogen or nitro, and n is 0, 1, 2 or 3, R2 is hydrogen, C1-4 alkyl or C2-4 alkenyl, R3 | 08/16/1994 |
| 5304657 | Hydrazine compounds usesful as pesticides A hydrazine compound of the formula (I) or its salt: ##STR1## wherein A is a benzofuranyl group which may be substituted, a quinolinyl group which may be substituted, a benzothienyl group which may be substituted, a benzothiazolyl group which may be ... | 04/19/1994 |
| 5252749 | Ethers of thienocyclopentanone oximes, their preparation and pharmaceutical compositions containing them The compounds of the invention having the formula: ##STR1## in which: A, which is a ring condensed with cyclopentane, represents a substituted or unsubstituted thiophene ring, Q represents an alkylene chain, R1 and R2 each repre... | 10/12/1993 |
| 5250565 | Indole-,benzofuran-,and benzothiophene-containing lipoxygenase-inhibiting compounds Pro-drugs of potent 5-lipoxygenase inhibiting compounds comprise compounds of the formula ##STR1## in which A is an alkylene or alkenylene group, X is oxygen, sulfur, sulfoxyl, or substituted nitrogen, and Y is a group which includes substituted... | 10/05/1993 |
| 5208253 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo(b) thiophene-2-carboxamides as inhibitors of cell adhesion 3-Alkyloxy-, aryloxy-, or arylalkyloxy-benzo[b]thiophene-2-carboxamides are described as agents which block leukocyte adherence to vascular endothelium and, as such, are effective therapeutic agents for treating inflammatory diseases. Certain of these com... | 05/04/1993 |
| 5187192 | Cyclobutyl derivatives having lipoxygenase inhibitory activity Compounds of the structure ##STR1## where M is a pharmaceutically acceptable cation or a metabolically cleavable group, R is alkyl, cycloalkyl or --NR1 R2, where R1 and R2 are hydrogen, alkyl, cycloalkyl or... | 02/16/1993 |
