Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 7371872 | Prodrugs of excitatory amino acids This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorders and psych... | 05/13/2008 |
| 7173043 | Heteroaromate OSC inhibitors The present invention relates to heteroaromate OSC inhibitors. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vasc... | 02/06/2007 |
| 7058213 | Scanning system and calibration method for capturing precise three-dimensional information of objects A scanning system includes a hand-held scanning device that generates two-dimensional images of a pattern reflected off an object. The system also includes a memory and processing unit. The memory stores a calibration table for the scanner and received scanned bitma... | 06/06/2006 |
| 6927298 | 3,4-alkylenedioxythiophenedioxide compounds and polymers comprising monomeric units thereof A 3,4-alkylenedioxythiophenedioxide compound represented by formula (I): in which: A represents a C1-5-alkylene bridge; R represents an optionally substituted C1-24-alkyl, C3-18-cycloal... | 08/09/2005 |
| 6875787 | 10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula I; | 04/05/2005 |
| 6686390 | Compounds having antiinflamatory activity: process for their preparation and pharmaceutical compositions containing them The present invention relates to novel heterocyclic compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their regioisomers, their polymorphs, their pharmaceutically acceptable salts, their p... | 02/03/2004 |
| 6465508 | Preparation and use of ortho-sulfonamido aryl hydroxamic acids as matrix metalloproteinase inhibitors Ortho-sulfonamido aryl hydroxamic acids are provided which are useful, inter alia, for the inhibition of matrix metalloproteinases and the treatment of conditions associated with overexpression of MMPs.... | 10/15/2002 |
| 6420391 | Fused thiophone derivatives and drugs containing the same as the active ingredient The present invention relates to a fused thiophene derivative of the formula (I) (wherein all the symbols are defined as described in the specification) and an inhibitor of producing interleukin-6 and/or interleukin-12 comprising the said derivative as an... | 07/16/2002 |
| 6355386 | Liquid crystalline filter dyes for imaging elements This invention is a dispersion comprising a solvent having dispersed therein a liquid-crystal forming dye of structural Formula I: [D--(X)m ]--(Y)n I wherein: D is a merocyanine dye; each Y contains an ionic or a nonionic solubilizing substit... | 03/12/2002 |
| 6281240 | Diarylsulfonylureas for use in treating secretory diarrhea This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea. This invention also describes specific diarylsulfonylureas f... | 08/28/2001 |
| 6245255 | Liquid crystalline filter dyes for imaging elements A dispersion comprises a solvent having dispersed therein a liquid-crystal forming dye of structural Formula I, II or III: ##STR1## wherein the substituent are as defined in the specification. The dispersion is particularly useful in imaging and photographic e... | 06/12/2001 |
| 6217642 | Benzothiophene-2-carboxamide s,s-dioxides for use in anti-fouling applications A method and composition for protection against fouling of objects which come into contact with sea water or brackish water comprising a benzothiophene-2-carbomide S,S-dioxide as the essential component are described.... | 04/17/2001 |
| 6207686 | Endothelin antagonists A compound of formula (I), in which: R1 is lower alkyl, cyclo(lower)alkyl, optionally substituted aryl, optionally substituted heterocyclic group, cyclo(lower)alkyl(lower)alkyl, or ar(lower)alkyl; R2 is hydrogen, hydroxy or protected... | 03/27/2001 |
| 6194450 | Polyaromatic heterocyclic compounds and pharmaceutical compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic heterocyclic compounds have the structural formula (I): ##STR1## in which Z is a divalent radical selected from among --O--, --S-- or --Nr'-- and Ar is either a radical having the following structura... | 02/27/2001 |
| 6169087 | Modulators of protein tyrosine phosphatases (PTPases) The present invention provides novel compounds of Formula 1 or Formula 2 and compositions thereof, methods of their use, and methods of their manufacture, ##STR1## wherein X, Y, Z, W, R1, R2 and R3 are defined more fully i... | 01/02/2001 |
| 6103912 | Photographic products and processes A novel class of bridged indicator dyes is disclosed which possess absorption in the infrared region of the electromagnetic spectrum. These bridged indicator dyes are useful as light-absorbing, pH-sensitive optical filter agents in diffusion transfer phot... | 08/15/2000 |
| 6063936 | Aromatic carboxylic acid bicyclic sulfur compounds An aromatic carboxylic acid bicyclic sulfur compound of the following formula: ##STR1## wherein X1 is selected from the group consisting of C1 to C4 alkyl, halogen, C1 to C4 haloalkyl, C2 | 05/16/2000 |
| 6028069 | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter Cyclic sulphones of formula (I) are disclosed, in which: R1 and R2 each independently of one another stand for H, A, CF3, CH2 F, CHF2, C2 F5, Hal, OH, OA, NH2, NHA, NA... | 02/22/2000 |
| 5989451 | Compounds and methods for doping liquid crystal hosts This invention provides chiral thioindigo compounds for doping smectic liquid crystal hosts, wherein the compounds modulate a chiral bulk property of an induced chiral smectic liquid crystal phase upon irradiation at a wavelength in the visible range. Mod... | 11/23/1999 |
| 5986109 | Benzothiophene compounds, intermediates, compositions, and methods A compound of fomula XIV: ##STR1## wherein: R1a is --H or --OR7a in which R7a is a hydoxy protecting group; R2a is --H, halo, or OR8a in which R8a is a hydroxy protecting group; and R | 11/16/1999 |
| 5981765 | Benzothiophene compounds, intermediates, compositions, and methods The present invention provides a compound of formula ##STR1## wherein R1a is --H or --OR7a in which R7a is a hydroxy protecting group; R2a is --H, halo, or --OR8a in which R8a is a hydroxy ... | 11/09/1999 |
| 5977382 | Benzo[b]thiophene compounds, intermediates, processes, compositions, and methods The instant invention provides novel benzo[b]thiophene compounds, intermediates, compositions, pharmaceutical formulations, and methods of use.... | 11/02/1999 |
| 5863936 | Telomerase inhibitors Methods and compositions for treating cancer and other diseases in which inhibition of telomerase activity can ameliorate disease symptoms or prevent or treat the disease relate to compounds characterized by the following structure: ##STR1## and... | 01/26/1999 |
| 5849798 | Polyaromatic heterocyclic compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic heterocyclic compounds have the structural formula (I): ##STR1## in which Z is a divalent radical selected from among --O--, --S-- or --Nr'-- and Ar is either a radical having the following stru... | 12/15/1998 |
| 5789436 | 4,6 Di-t-butyl-5-hydroxy-2,3-dihydrobenzothiophene A compound represented by formula (I): ##STR1## wherein R1 represents a hydrogen atom, a lower alkyl group or an acyl group; R2 and R3, which may be the same or different, each represents a hydrogen atom, an optionall... | 08/04/1998 |
| 5747540 | HIV protease inhibitors useful for the treatment of AIDS Compounds such as ##STR1## or pharmaceutically acceptable salts thereof, are HIV protease inhibitors. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically ... | 05/05/1998 |
| 5712304 | Carboxylic acid amide benzothiophenecarboxamide s-oxides New benzothiophenecarboxamide S-oxides of the formula (I) ##STR1## in which R1 represents optionally substituted alkyl, or represents alkenyl or alkinyl, or represents in each case optionally substituted cycloalkyl or cycloalkylalkyl, or r... | 01/27/1998 |
| 5686471 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents A compound having the structure: ##STR1## wherein (a) n is from about 1 to about 3; (b) X is selected from the group consisiting of O, S, SO, or SO2 ; (c) Y is independently hydrogen or straight, branched or cyclic alkyl or aralkyl having from ... | 11/11/1997 |
| 5684031 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents A compound having the structure: ##STR1## wherein (a) n is from 1 to about 3; (b) X is selected from the group consisting of O, S, SO, or SO2 ; (c) Y is independently hydrogen or straight, branched or cyclic alkyl having from 1 to about 4 ... | 11/04/1997 |
| 5684041 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents A compound having the structure: ##STR1## wherein (a) n is from 1 to about 3; (b) X is selected from the group consisiting of O, S, SO, or SO2 ; (c) Y is independently hydrogen or straight, branched or cyclic alkyl having from 1 to about 4 carb... | 11/04/1997 |
| 5646121 | Pseudopeptides with antiviral activity The present invention relates to novel pseudopeptides with antiviral activity of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to a process for their preparation, and to their use as antiviral a... | 07/08/1997 |
| 5637719 | Reagents for rapid peptide synthesis The compounds of the present invention are adaptable as blocking or protecting groups for an amine composition useful in peptide synthesis. The present invention is directed to a method of protecting an amino group of an organic molecule during a reaction... | 06/10/1997 |
| 5633231 | Valine-containing pseudopeptides with antiviral activity The present invention relates to valine-containing, substituted pseudopeptides of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to processes for their preparation, and to their use as anti-viral... | 05/27/1997 |
| 5591833 | Colorants and intermediates therefor having branched poly(oxyalkylene)moieties, and their manufacture Colorants and compositions useful as a fugitive or permanent colorant for a variety of substrates, or as intermediates for their manufacture, and having one or more improved properties of enhanced aqueous washability, compatibility with and non-extractibi... | 01/07/1997 |
| 5567827 | 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives The subject of the invention is 4-hydroxyphenylthio derivatives of general formula: ##STR1## in which: R1 and R2, which are identical or different, each represent hydrogen, a methyl or ethyl radical or a halogen atom, R represen... | 10/22/1996 |
| 5547980 | Bicyclic sulfones, processes for their production and pharmaceutical agents containing them Bicyclic sulfones of the formula I ##STR1## in which Y is a halogen atom, Z is a halogen atom or hydrogen, m and n, that are different and represent an integer 0 or 1, A and B each represent hydrogen or together represent a valency bond, X1 and X | 08/20/1996 |
| 5532254 | Modulation of calcium channels using benzothiophenes A method for modulating calcium channels, increasing the density of calcium channels in vascular and cardiac tissue with no changes in inotropic or pressor response, comprising administering to a warm-blooded animal in need thereof a pharmaceutically-effe... | 07/02/1996 |
| 5510491 | Reagents for rapid peptide synthesis This invention relates to compounds of the formula: ##STR1## wherein R is an electron withdrawing group; R1 is H or COZ; X1 and X2 are independently H, lower alkyl, aryl, aryl lower-alkyl or polystyrene or R and X1 t... | 04/23/1996 |
| 5508431 | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives The subject of the invention is 4-hydroxyphenylthio derivatives of general formula: ##STR1## in which: R1 and R2, which are identical or different, each represent hydrogen, a methyl or ethyl radical or a halogen atom, R represen... | 04/16/1996 |
| 5498630 | Fungicides for the control of take-all disease of plants A method of controlling Take-All disease of plants by applying a fungicide of the formula ##STR1## wherein Z1 and Z2 are C and are part of an aromatic ring which is benzothiophene; and A is selected from --C(X)-amine wherein the amine is an unsubstit... | 03/12/1996 |
