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Patent No. 6637829

Decorative Jeweled Wheel Cover

An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.

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Class 549/494 - Having -C(=X)-, wherein X is chalcogen, attached indirectly to the hetero ring by nonionic bonding


Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which a -- group, wherein X is chalcogen (i.e.,
No. of patents: 120
Last issue date: 06/15/2010


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NumberTitleIssue Date
7737288Non-steroidal androgen receptor modulators, preparation process, pharmaceutical composition and use thereof
Non-steroidal androgen receptor modulating compounds of the general formula (I), their pharmaceutically acceptable salts, preparation process and pharmaceutically compositions containing the said compounds are disclosed. Such compounds of the general formula (I) or ...
06/15/2010
7259166Substituted-cycloalkyl and oxygenated-cycloalkyl glucokinase activators
2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of...
08/21/2007
71324453,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disor...
11/07/2006
7071342Synthesis of 2-hydroxy-N,N-dimethyl-3-[ [2-[1 (R)-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]aminobenzamide
Disclosed is a process for making the compound of formula I: using the compounds of formulas II, Q, and XI or XII: wherein A is selected from the group consi...
07/04/2006
7049308C-nitroso compounds and use thereof
A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less th...
05/23/2006
7030239Compounds to treat Alzheimer's disease
The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) useful in treating Alzheimer's disease and other similar diseases. ...
04/18/2006
6906092Method of inhibiting matrix metalloproteinases
The present invention relates to a method of inhibiting matrix metalloproteinases using compounds that are dibenzofuran sulfonamide derivatives having the Formula I More particularly, the present invention relates to a m...
06/14/2005
6743564Amine compounds, resist compositions and patterning process
Amine compounds having a cyano group are useful in resist compositions for preventing a resist film from thinning and also for enhancing the resolution and focus margin of resist. ...
06/01/2004
67101903-heteroarylalkyl substituted gaba analogs
The invention is a novel series of compounds which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IB...
03/23/2004
6710071Difluoromethylene aromatic ethers as inhibitors of glycine transport
This invention relates to a series of difluoromethylene aromatic ethers of the formula wherein ring A and X and Y are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmace...
03/23/2004
6605608Amino acid derivatives and drugs containing the same as the active ingredient
The present invention relates to the compounds of the formula (I) and salts thereof (all the symbols are the same meanings as described in the specification). ##STR1## The compounds of the formula (I) possess inhibitory activity of N-type calcium cha...
08/12/2003
6593352Substituted anthranilic acids, their use as a medicament or diagnostic, and medicament comprising them, and a pharmaceutical combination preparation containing a sodium/hydrogen exchange (NHE) blocker
Substituted anthranilic acids of the formula I ##STR1## their use as a medicament or diagnostic, and medicament comprising them, and a pharmaceutical combination preparation containing a sodium/hydrogen exchange (NHE) blocker....
07/15/2003
6579987Diaryl-enynes
Provided, among other things, is a compound of Formula I: ##STR1## wherein: Ar1 and Ar2 are independently selected aryl groups, optionally substituted with up to five substituents independently selected from the group consisting of a...
06/17/2003
6548538Propionic acid derivatives
The present application relates to novel potent PPAR-alpha-activating compounds for treating, for example, coronary heart disease, and to their preparation....
04/15/2003
6444840C11 oxymyl and hydroxylamino prostaglandins useful as FP agonists
The invention provides novel prostaglandin analogs. In particular, the present invention relates to compounds having a structure according to formula (I) wherein R1, R2, R3, R4, R5, R6, W, ...
09/03/2002
6410780C11 oxymyl and hydroxylamino prostaglandins useful as medicaments
The invention provides novel prostaglandin analogs. In particular, the present invention relates to compounds having a structure according to formula (I) wherein R1, R2, R3, R4, R5, R6, W, ...
06/25/2002
6391918N-sulphonyl and N-sulphinyl phenylglycinamide
Novel ଱-amino acid amides of formula (I) as well as possible isomers and mixtures of isomers thereof, wherein the substituents are defined as follows: n is the number zero or one; R1 is optionally substituted alkyl, alkenyl, alkynyl, cycl...
05/21/2002
6316630Synthesis of epothilones, intermediates thereto and analogues thereof
The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are int...
11/13/2001
6204388Synthesis of epothilones, intermediates thereto and analogues thereof
The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are int...
03/20/2001
6174915Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses
The present invention is directed to compound of the formula I: ##STR1## wherein R1, R2, R3, R4, R5, X, Y, and ##STR2## are as defined herein. These compounds are useful for inhibiting the activity of a ...
01/16/2001
6153591Dipeptide caspase inhibitors and the use thereof
The present invention is directed to novel dipeptides represented by the general Formula I: ##STR1## where R1 -R2 and AA are defined herein. The present invention relates to the discovery that compounds having Formula I are pote...
11/28/2000
6107512Process for making optically active ଱-amino ketones and selected novel optically active ଱-amino ketones
The invention includes selected novel optically active ଱-amino ketones which either are themselves useful or are intermediates for the preparation of known ketomethylene pseudopeptides useful as antibiotics, antibiotic enhancers, or enzyme inhibitor...
08/22/2000
6037498Chiral syntheses
This invention relates to novel compounds of general formula (I) ##STR1## wherein R1 represents an organic group, R2 represents a hydrogen atom or an organic group, and the asterisk denotes that the group R1 is predom...
03/14/2000
6017918Phenyl glycine compounds and methods of treating atherosclerosis and restenosis
The present invention provides compounds having the Formula I ##STR1## The present invention also provides methods of treating atherosclerosis, coronary heart disease, and restenosis using the compounds of Formula I, and pharmaceutical compositions c...
01/25/2000
5856323Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chemotaxis and respira...
01/05/1999
5840961Asymmetric synthesis of chiral beta-amiNo acids
The invention herein is directed to a process for the preparation of ethyl 3S-amino-4-pentynoate which involves treating 3-(trimethylsilyl)-2-propynal with L-phenylglycinol in toluene to produce ଱S-››3-(trimethylsilyl)-2-propynylidene amino!benzen...
11/24/1998
5739361Process for the preparation of furosemide
A new process for the preparation of furosemide ›4-chloro-N-(2-furylmethyl)-5-sulfamoyl-anthranilic acid!comprising the photochlorination of 4-chloro-2-fluoro-toluene to give 4-chloro-2-fluoro-benzotrichloride, the aminosulfonylation of the same and ...
04/14/1998
5604256Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition
Compounds of formula (I): ##STR1## (in which: R is hydrogen, methyl or hydroxy; X is alkyl, alkenyl, cycloalkyl, aryl, aralkyl, or a heterocyclic group; A is a single bond, or an alkylene, alkenylene, alkynylene or alkadienylene group; Y is hydrogen,...
02/18/1997
5597839Di(aromatic) compounds and their use in human and veterinary medicine and in cosmetics
Di(aromatic) compounds corresponding to the following formula: ##STR1## in which: Ar represents either ##STR2## X represents a divalent radical, Z represents O, S or a divalent radical, and R1, R2, R3, R4 a...
01/28/1997
5532267Amidinonaphthyl furancarboxylate derivatives and acid addition salts therof
Amidinonaphthyl furancarboxylate derivatives of the formula I ##STR1## wherein A is a single bond or A denotes (a) a phenyl group, cyclopentyl group, or cyclohexyl group, (b) an alkenylphenyl group, alkylphenyl group, phenylalkenyl group, or phenylal...
07/02/1996
5436244Indane derivatives and analgesic and diuretic compositions thereof
Novel indanes in all possible stereoisomer forms of the formula ##STR1## wherein the substituents are as defined in the specification and their non-toxic, pharmaceutically acceptable acid addition salts and their hydrates having central analgesic pro...
07/25/1995
5434151Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chemotaxis and respira...
07/18/1995
5434181Furanyl insecticide
The present invention relates to novel (tetrahydro-3-furanyl)methylamino derivatives of the following formula (1): ##STR1## wherein the variables are defined in the specification, which are useful as insecticides....
07/18/1995
5399690Filter dyes for photographic elements
Solid particle dispersions of dyes according to the formula: ##STR1## wherein D is selected from the group consisting of ##STR2## and ketomethylene nuclei are disclosed as filter dyes for photographic elements. In this formula, E1 and...
03/21/1995
5358938Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
2,5-Diaryl tetrahydrofurans, 2,5-diaryl terahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiphenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chemotaxis and respirato...
10/25/1994
5330965Cyclohexenone oxime ethers and their use as herbicides
Cyclohexenone oxime ethers of the formula I ##STR1## (R1 =C1 -C6 -alkyl; A=substituted or unsubstituted alkylene or alkenylene; Z=a 5-membered or 6-membered heteroaromatic structure; X=substituted or unsubstituted amino, n...
07/19/1994
52907564-trifluoromethyl-4'-nitrodiphenyl ethers
Compounds of the formula: ##STR1## wherein X is hydrogen, halo, trihalomethyl, alkyl, nitroor cyano; X1 is hydrogen, halo, or trihalomethyl; R1 and R2 are hydrogen, alkyl phenyl or benzyl; n is 1 to 5, and Z is halo, ...
03/01/1994
5254573Substituted heterocyclic derivatives useful as platelet aggregation inhibitors
Novel substituted heterocyclic derivatives are provided which inhibit platelet aggregation. This invention also pertains to pharmaceutical compositions and methods of using such derivatives....
10/19/1993
5234946Substituted alkylamine derivatives
The substituted alkylamine derivatives represented by formula (I) ##STR1## wherein R1 represents (a) substituted or unsubstituted C2-6 alkenyl group, (b) substituted or unsubstituted C3-6 cycloalkenyl group, (c) subst...
08/10/1993
5214206Aminosulfonyl urea ACAT inhibitors
The present invention provides pharmaceutically useful compounds which are aminosulfonyl urea compounds which are ACAT inhibitors rendering them useful in controlling blood cholesterol levels, pharmaceutical compositions and methods of using the ACAT inhi...
05/25/1993
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