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| Number | Title | Issue Date |
| 8058458 | Processes for the preparation and purification of hydroxymethylfuraldehyde derivatives A method for utilizing an industrially convenient fructose source for a dehydration reaction converting a carbohydrate to a furan derivative is provided. Recovery methods also are provided. Embodiments of the methods improve upon the known methods of producing furan... | 11/15/2011 |
| 7956203 | Oxidation of 5-(hydroxymethyl) furfural to 2,5-diformylfuran and subsequent decarbonylation to unsubstituted furan Alcohols are catalytically oxidized to aldehydes, in particular to benzaldehyde and diformylfuran, which are useful as intermediates for a multiplicity of purposes. The invention also relates to the polymerization of the dialdehyde and to the decarbonylation of the ... | 06/07/2011 |
| 7939681 | Methods for conversion of carbohydrates in ionic liquids to value-added chemicals Methods are described for converting carbohydrates including, e.g., monosaccharides, disaccharides, and polysaccharides in ionic liquids to value-added chemicals including furans, useful as chemical intermediates and/or feedstocks. Fructose is converted to 5-hydroxy... | 05/10/2011 |
| 7897794 | Method for purifying hydroxymethylfurfural using non-functional polymeric resins Disclosed are methods of at least partially purifying HMF from an aqueous mixture containing reactants and products of HMF synthesis from fructose that relies on use of non-functional polymeric resins. A first type of non-functional polymeric resin preferentially ad... | 03/01/2011 |
| 7579489 | Processes for the preparation and purification of hydroxymethylfuraldehyde and derivatives A method for utilizing an industrially convenient fructose source for a dehydration reaction converting a carbohydrate to a furan derivative is provided. Recovery methods also are provided. Embodiments of the methods improve upon the known methods of producing furan... | 08/25/2009 |
| 7572925 | Catalytic process for producing furan derivatives in a biphasic reactor Described is a catalytic process for converting sugars to furan derivatives (e.g. 5-hydroxymethylfurfural, furfural, dimethylfuran, etc.) using a biphasic reactor containing a reactive aqueous phase and an organic extracting phase. The process provides a cost-effect... | 08/11/2009 |
| 7411078 | Method for producing furan-2,5-dicarboxylic acid A method for producing furan-2,5-dicarboxylic acid (FDCA) is provided which can efficiently and quantitatively producing FDCA under mild conditions, without employing an expensive catalyst and with a reduced energy consumption. A furan ring compound having two funct... | 08/12/2008 |
| 7101878 | Non-peptide GNRH agents, methods and intermediates for their preparation Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorde... | 09/05/2006 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 6963010 | Hydrophobic polyamine analogs and methods for their use The disclosed invention provides new polyamine analogs and derivatives containing a hydrophobic region and a polyamine region as well as methods and compositions for their use. ... | 11/08/2005 |
| 6603026 | Heterocyclic compounds produced from biomass Sugars derived from acidic hydrolysis of biomass consist of glucose and xyloses which are subjected to dehydration, within the hydrolysis environment, to form heterocyclic compounds, furfural and hydroxymethylfurfural. By providing a vessel for hydrolysis... | 08/05/2003 |
| 6589970 | 6-(aryl-amido or aryl-amidomethyl)-naphthalen-2-yloxy-acidic derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) This invention provides novel compounds, pharmaceutical compositions and methods of treating thrombotic disorders in mammals, the compounds having the formula: ##STR1## Wherein: Ar is phenyl, naphthyl, furanyl, benzofuranyl, indolyl, pyrazolyl, oxazo... | 07/08/2003 |
| 6420392 | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes are disclosed that reduce the chemotaxis and respiratory burst leading to the formation of damaging oxygen radicals of polymorphonuclear leukocytes during an inflammato... | 07/16/2002 |
| 6369225 | Compounds having activity as inhibitors of cytochrome P450RAI Compounds having Formula 8 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##... | 04/09/2002 |
| 6362166 | Antipicornaviral compounds and methods for their use and preparation Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating p... | 03/26/2002 |
| 6353119 | Preparation of 3-substituted-4-arylquinolin-2-one derivatives The present invention relates to a process for the preparation of 3-substituted-4-arylquinolin-2-one derivatives from a substituted coumarin and using a photochemical cyclization method on a dihydrofuran intermediate.... | 03/05/2002 |
| 6255340 | Pesticidal composition A pesticidal composition comprising prallethrin and a neonicotinoid compound given in the following formula (1), (2) or (3), as an active ingredient ##STR1## wherein, A represents a 6-chloro-3-pyridyl, 2-chloro-5-thiazolyl, tetrahydrofuran-2-yl, tetr... | 07/03/2001 |
| 6150397 | 5-aroylnaphthalene derivatives as anti-inflammatory agents The present invention relates to certain 5-aroylnaphthalene derivatives of formula (I): ##STR1## that are inhibitors of prostaglandin G/H synthase, pharmaceutical compositions containing them, methods for their use, and methods for preparing the... | 11/21/2000 |
| 6127576 | Aminophenyl ketone derivatives and a method for the preparation thereof The present invention provides o-aminophenyl ketone derivatives which are intermediates useful in the manufacture of herbicidal sulfamoyl urea compounds, including the crop selective herbicide 1-{[o-(cyclopropylcarbonyl)phenyl]-sulfamoyl}-3-(4,6-dimethoxy... | 10/03/2000 |
| 6124502 | Mercaptoketones and mercaptoalcohols and a process for their preparation This invention relates to matrix metalloproteinase (MMP) inhibiting compounds of the formula: ##STR1## where R1 is C1 -C12 alkyl, straight or branched and optionally substituted by halogen, hydroxy, C1 -C | 09/26/2000 |
| 6103708 | Furans, benzofurans, and thiophenes useful in the treatment of insulin resistance and hyperglycemia This invention provides compounds of Formula I having the structure: ##STR1## wherein R1, R2, R3, R4, R5, R6, R7, R8, W, X, Y, and Z are as defined in the specificatio... | 08/15/2000 |
| 6100253 | Tricycle substituted with azaheterocyclic carboxylic acids The present invention relates to novel N-substituted azaheterocyclic compounds of the general formula ##STR1## wherein X, Y, Z, R1, R2 and r are as defined in the detailed part of the present description, or salts thereof, to me... | 08/08/2000 |
| 6054611 | Method for the production of levulinic acid and its derivatives A method of producing dehydration products from one more 5-carbon or 6-carbon sugars includes reacting said one or more sugars at 40-240° C. for 1 to 96 hours in the presence of 5-90% sulfuric acid, separating the reaction products, and recovering levuli... | 04/25/2000 |
| 6037367 | Substituted-pent-4-ynoic acids Compounds of formula (I) wherein: R1 is --(CR4 R5)n C(O)O(CR4 R5)m R6, --(CR4 R5)n C(O)NR4 (CR4 R5)m | 03/14/2000 |
| 5905166 | Type of dye in photographic materials A new type of yellow dyes with general formula Q-CO--CO--X is disclosed. They can be used in photographic materials as antihalation dyes, acutance dyes or filter dyes. Preferably they are incorporated in UV sensitive contact materials for pre-press applic... | 05/18/1999 |
| 5856530 | Antipicornaviral compounds and methods for their use and preparation Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating p... | 01/05/1999 |
| 5856323 | Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chemotaxis and respira... | 01/05/1999 |
| 5716624 | Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (1): ##STR1## in which X is one of the radicals: ##STR2## and are useful for the treatment of a wide variety of disease states, whether h... | 02/10/1998 |
| 5663199 | Anti-viral aromatic O-alkylated oximes, ethers and thioethers Compounds of the formula ##STR1## wherein Q is ##STR2## R1 is hydrogen or halogen R2 is hydrogen or halogen; R3 is hydrogen or C1 -C4 alkyl; R4 is C3 -C6 alkenyl ... | 09/02/1997 |
| 5648486 | Compounds and methods for the treatment of inflammatory and immune disorders 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chemotaxis and respira... | 07/15/1997 |
| 5610320 | Sulfonamide phenyl substituted compounds Sulfonamide compounds of the formula or pharmacologically acceptable salts thereof: ##STR1## wherein: R1 is a hydrogen atom, halogen atom, lower alkyl group, lower alkoxy group, hydroxyl group, nitro group, phenoxy group, cyano group,... | 03/11/1997 |
| 5610319 | Compound useful as antiproliferative agents and GARFT inhibitors The invention generally relates to compounds of the formula I, which are in equilibrium with their 4-hydroxy tautomers, and their pharmaceutically acceptable salts: ##STR1## where n is 0 to 2; A is S, CH2, O, NH or Se, and when n is 0, A i... | 03/11/1997 |
| 5594152 | Process for the preparation of tricyclic-heterocycles This invention comprises a process for production of a compound of the formula: ##STR1## in which R1 is selected from the group consisting of H, lower alkyl(C1 -C3), alkoxy(C1 -C3), bromo, chloro... | 01/14/1997 |
| 5591756 | LTB4 synthesis inhibitors This invention relates to a compound of the formula: ##STR1## or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, --CH.dbd.CH--, or --CH.dbd.N--; wherein R1 is --CO2 R2 or tetrazole; wherein R2 | 01/07/1997 |
| 5585486 | Peptidic ketones as interleukin-1ଲ-converting enzyme inhibitors Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein R1 is (CR5 R6)n, (CR5 R6)n,-aryl, (CR5 R6) | 12/17/1996 |
| 5463083 | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes are disclosed that reduce the chemotaxis and respiratory burst leading to the formation of damaging oxygen radicals of polymorphonuclear leukocytes during an inflammato... | 10/31/1995 |
| 5457237 | Dihydroxyindanone tyrosine kinase inhibitors Certain dihydroxyindanone compounds, and their pharmaceutically-acceptable salts, are inhibitors of tyrosine kinase enzymes, and so are useful for the control of tyrosine kinase dependent diseases (e.g., cancer, atherosclerosis).... | 10/10/1995 |
| 5446067 | Oxime ethers and fungicides containing them Oxime ethers of the formula ##STR1## wherein m, G, R, R1, X, Y, and Z are as defined herein and fungicides containing these compounds.... | 08/29/1995 |
| 5434151 | Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chemotaxis and respira... | 07/18/1995 |
| 5358938 | Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase 2,5-Diaryl tetrahydrofurans, 2,5-diaryl terahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiphenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines are disclosed that reduce the chemotaxis and respirato... | 10/25/1994 |
