Did You Know...
...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 7829732 | High-yield conversion of cellulosic biomass into furanic biofuels and value-added products Paper, cotton, corn stover, straw, and wood are converted into furanic products in high yields (based on their cellulose content) using a simple, inexpensive process involving concurrent hydrolysis, dehydration, and substitution reactions coupled with continuous ext... | 11/09/2010 |
| 7417068 | EPreceptor antagonists A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein one of R2 and R5 is: (i) H or an optionally substituted C1-4 a... | 08/26/2008 |
| 7388101 | Tetrahydrofuran derivatives having cis substituent, their intermediates, and their preparation method The present invention relates to a tetrahydrofuran compound having cis substituents, the derivatives thereof and a process for preparing the same, and in particular relates to a dihydrofuran-3-ylidene triflate compound having cis substituents at C2 and C | 06/17/2008 |
| 7371396 | Dermatological and cosmetic compositions The present invention relates to a dermatological and/or cosmetic composition comprising a furfuryl derivative of formula (I), and its use in the treatment of dermatological disorders especially when caused by free radicals. ... | 05/13/2008 |
| 7365094 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents The present invention relates to compounds of the general formula (II) and salts and physiologically functional derivatives thereof, for the use as a medicament. ... | 04/29/2008 |
| 7317116 | Processes for the preparation and purification of hydroxymethylfuraldehyde and derivatives A method for utilizing an industrially convenient fructose source for a dehydration reaction converting a carbohydrate to a furan derivative is provided. Recovery methods also are provided. Embodiments of the methods improve upon the known methods of producing furan... | 01/08/2008 |
| 7271210 | Stabilized ester compositions and their use in film-forming compositions This invention relates to a composition comprising, consisting of or alternatively consisting essentially of a stabilized furfural or glycol ester of a vegetable oil fatty acid and an antioxidant such as butylated hydroxy toluene. This invention also relates to late... | 09/18/2007 |
| 7183318 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them The invention concerns compounds of formula (1): R-A-R′ wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; Râ... | 02/27/2007 |
| 7161015 | Method of making 2-furylalkylketones A method of making a compound by: providing a furyl compound being 2-furoyl chloride or corresponding carboxylic acid, amide, ester, anhydride, or lactone; reacting the furyl compound with CH3O(CH3)NH.HCl to form an amide; reacting the amide wi... | 01/09/2007 |
| 7129364 | Process for the preparation of 2-furyl-n-pentylketone and longer chain analogs A process of making furfural-derived ketones is disclosed. These compounds may be useful as marine antifouling agents. The process uses the steps of: reacting a furfural with 1,3-dithiopropane to form a 1,3-dithiane derivative; metalizing the 1,3-dithiane derivative... | 10/31/2006 |
| 7098201 | Heteroaromatic derivatives having an inhibitory activity against HIV integrase A compound of the formula (I): wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is —COORA wherein RA is hydrogen or ester residue, —CONRBRC wher... | 08/29/2006 |
| 7078542 | Nonlinear optical compounds and methods for their preparation Nonlinear optically active compounds, methods for making nonlinear optically active compounds, compounds useful for making nonlinear optically active compounds, methods for making compounds useful for making nonlinear optically active compounds, macrostructures that... | 07/18/2006 |
| 7053109 | Aminediols for the treatment of Alzheimer's disease The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the... | 05/30/2006 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 6946462 | N-monoacylated derivatives of o-phenylenediamines, their analogs and their use as pharmaceutical agents New compounds represented by the formula or pharmaceutically acceptable salts or prodrugs thereof, wherein X1 and X2 are each independently selected from a CH group or a nit... | 09/20/2005 |
| 6924396 | α-haloenamine reagents The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use. ... | 08/02/2005 |
| 6903132 | Non-peptide GnRH agents, pharmaceutical compositions and methods for their use Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and ster... | 06/07/2005 |
| 6878740 | Substituted C-furan-2-yl-methylamine and C-thiophen-2-yl-methylamine compounds Substituted C-furan-2-yl-methylamine and C-thiophen-2-yl-methylamine compounds, processes for their preparation, medicaments and pharmaceutical compositions containing them, and their use in treatment methods and in the preparation of analgesics, in the preparation ... | 04/12/2005 |
| 6869953 | N-monoacylated derivatives of o-phenylenediamines, their analogs and their use as pharmaceutical agents New compounds represented by the formula or pharmaceutically acceptable salts or prodrugs thereof, wherein X1 and X2 are each independently selected fr... | 03/22/2005 |
| 6849660 | Antimicrobial biaryl compounds Provided are antibacterial compounds having Formula I: In such compositions, X is O or S; Y is CH2; n is 0 or 1. One of R1 and R1′ is —C(O)NR5R5′ | 02/01/2005 |
| 6833453 | Methods of producing oxazolidinone compounds Methods of synthesizing pharmacologically useful oxazolidinones are disclosed, and, in particular, a method of manufacturing a 5-(tert-butylcarbamoyl)-aminomethyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamin... | 12/21/2004 |
| 6812229 | Carbamate derivative and agricultural/horticultural fungicide It is to provide a novel fungicide having high controlling effects on plant diseases particularly on wheat powdery mildew and cucumber gray mold, without ill effects on crops. A carbamate derivative represented by the general formula [I] | 11/02/2004 |
| 6790866 | Sulfonamide and carboxamide derivatives and drugs containing the same as the active ingredient The sulfonamide or carboamide derivatives of the formula (I) and a pharmaceutical composition which comprise them as an active ingredient: (wherein A ring, B ring is carbocyclic ring, heterocyclic ring; Z1 is ... | 09/14/2004 |
| 6790953 | Ether compounds The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a compo... | 09/14/2004 |
| 6753391 | Ring-opened azlactone chain transfer agents for radical polymerization Chain transfer agents for controlled radical polymerizations (RAFT) are described. The chain transfer agents have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 06/22/2004 |
| 6747104 | Azlactone photoiniferters for radical polymerization Photoiniferters for controlled radical polymerizations are described. The photoiniferters have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 06/08/2004 |
| 6693209 | Synthesis of anhydroglycitol esters of improved colour Diesters of dianhydroglycitols can be prepared by esterification of dianhydroglycitols, anhydroglycitols and/or glycitols with alkylcarboxylic or arylcarboxylic acids in the presence of an acid catalyst, the acid catalyst being a macroporous acid ion exch... | 02/17/2004 |
| 6677487 | -haloenamine reagents The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.... | 01/13/2004 |
| 6620841 | Aromatic heterocycle compounds having HIV integrase inhibiting activities A compound of the formula (I): ##STR1## wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is --COORA wherein RA is hydrogen or ester residue, --CONRB RC wherein RB and RC... | 09/16/2003 |
| 6506788 | N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders The present invention relates to pharmaceutical compositions comprising and methods of using an N-linked urea or carbamate of a heterocyclic thioester for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory perfor... | 01/14/2003 |
| 6492338 | Therapeutic agents Therapeutic or preventive agents for diseases due to the action of aldose reductase; and aldose reductase inhibitors, characterized by containing at least one compound having an aldose reductase inhibiting activity which is selected from among 2,5-dihydro... | 12/10/2002 |
| 6448290 | Sulfonamide and carboxamide derivatives and drugs containing the same as the active ingredient The sulfonamide or carboamide derivatives of the formula (I) and a pharmaceutical composition which comprise them as an active ingredient: ##STR1## (wherein A ring, B ring is carbocyclic ring, heterocyclic ring; Z1 is --COR1, --CH.db... | 09/10/2002 |
| 6420392 | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders 2,5-Diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes are disclosed that reduce the chemotaxis and respiratory burst leading to the formation of damaging oxygen radicals of polymorphonuclear leukocytes during an inflammato... | 07/16/2002 |
| 6407249 | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing a substituted phenylenediamine group Compounds of the formula: ##STR1## wherein R1 -R5 are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloalkyl... | 06/18/2002 |
| 6384249 | Compounds and methods for stabilization of furfural compositions Inhibitor compounds containing a moiety according to this invention are used to inhibit air oxidation and thermal polymerization of furfural or furfural derivatives. A process is provided for use of the inhibitors in the solvent refining of lubricating oi... | 05/07/2002 |
| 6362166 | Antipicornaviral compounds and methods for their use and preparation Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating p... | 03/26/2002 |
| 6326510 | Bi-aromatic compounds, compositions containing them and uses The invention relates to novel biaromatic compounds having general formula I ##STR1## and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for treating dermatological, rheumatic, respiratory, cardiovasc... | 12/04/2001 |
| 6303602 | Pyrrolidinyl and pyrrolinyl ethylamine compounds as kappa agonists A compound of the following formula: ##STR1## or a salt thereof, wherein A is hydrogen, halo, hydroxy; the broken line represents an optional double bond with proviso that if the broken line is a double bond, then A is absent; Ar1 is optionally... | 10/16/2001 |
| 6274741 | Process for the preparation of acyl heteroaromatic compounds from heteroaromatic compounds by metal ion exchanged clays The present invention relates to a process for the preparation of the acyl heteroaromatic compounds useful as important intermediates for drugs, pharmaceuticals and flavouring agents, said process comprising reacting an heteroaromatic compound selected fr... | 08/14/2001 |
| 6258775 | Bi-aromatic compounds, pharmaceutical and cosmetic compositions containing same and uses The invention relates to novel biaromatic compounds having general formula I ##STR1## and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for treating dermatological, rheumatic, respiratory, cardiovasc... | 07/10/2001 |
