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| Number | Title | Issue Date |
| 7507840 | Acceptor compounds useful for making hyperpolarizable organic chromophores Acceptor compounds useful for making hyperpolarizable organic chromophores having a π-donor conjugated to a π-acceptor through a π-bridge. ... | 03/24/2009 |
| 7425643 | Electron acceptors for nonlinear optical chromophores Electron acceptor compounds, nonlinear optical chromophores made from the electron acceptor compounds, methods for making the electron acceptor compounds and nonlinear optical chromophores, lattices that include the nonlinear optical chromophores, and devices that i... | 09/16/2008 |
| 7365089 | Triazolo-quinolin derivatives useful as adenosine receptor ligands The present invention relates to adenosine A3? receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the gen... | 04/29/2008 |
| 7344662 | Reverse synthetic methods for making organic non-linear optical materials A reverse synthetic strategy for making organic non-linear optical chromophores involves building up the chromophore from the electron-withdrawing end toward the electron-donating end. ... | 03/18/2008 |
| 7186742 | Benzamide inhibitors of the P2Xreceptor The present invention provides benzamide inhibitors of the P2X7 receptor of the formula: wherein R1–R3 are as defined herein. The compounds of the invention are useful in the tr... | 03/06/2007 |
| 7109214 | Substituted cyclopentene compounds The present invention relates to substituted cyclopentene compounds of the general formula I, to a process for the production thereof, to pharmaceutical preparations containing these compounds and to the use thereof for the production of pharmaceutical preparations.... | 09/19/2006 |
| 7084283 | Synthesis of fluorinated molecules possesing high optical non-linearity A compound of formula (I) wherein R′, R″, R′″, R″″, R′″″ can be selected from the group consisting of alkyl, aryl, a heteroatom, substituted alkyl and substituted aryl groups for use as a chromophore in electro-optic devices. ... | 08/01/2006 |
| 7078542 | Nonlinear optical compounds and methods for their preparation Nonlinear optically active compounds, methods for making nonlinear optically active compounds, compounds useful for making nonlinear optically active compounds, methods for making compounds useful for making nonlinear optically active compounds, macrostructures that... | 07/18/2006 |
| 7037937 | Cytotoxic compounds Compounds are described that bind to tubulin causing tubulin depolymerization and inhibiting tubulin polymerization. The compounds of the invention are therapeutically effective to inhibit cellular proliferation, for example, as effective anti-cancer agents. The com... | 05/02/2006 |
| 7029606 | Hyperpolarizable organic chromophores A dihydrofuran-containing nonlinear optical chromophore having a π-electron donor group conjugated to the dihydrofuran group through a π-electron conjugated bridge group. The nonlinear optical chromophore is a hyperpolarizable chromophore that can be used as an el... | 04/18/2006 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 7014796 | Nonlinear optical compounds and methods for their preparation Nonlinear optically active compounds, methods for making nonlinear optically active compounds, compounds useful for making nonlinear optically active compounds, methods for making compounds useful for making nonlinear optically active compounds, macrostructures that... | 03/21/2006 |
| 6841688 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone Disclosed is a method of preparing an optically pure (R)- or (S)-tetrahydrofuranyl ketone. By such a method, (R)- or (S)-2-tetrahydrofuran amide is converted to (R)- or (S)-2-tetrahydrofuran nitrile through dehydration in the presence of a dehydrating agent and an a... | 01/11/2005 |
| 6566375 | Elevation of HDL cholesterol by 4-[(aminothioxomethyl)-hydrazono]-N-(substituted)-4-arylbutanamides Compounds of this invention increase plasma levels of high density lipoprotein or HDL, the "good" cholesterol and as such may be useful for treating diseases such as atherosclerosis. These compounds are represented by the formula ##STR1## wherein: R | 05/20/2003 |
| 6541632 | Process for producing heterocyclic nitriles A carbocyclic or heterocyclic compound, ammonia and an oxygen-containing gas are subjected to fluid catalytic reaction in vapor phase in the presence of a catalyst containing alkali metal to produce an aromatic or heterocyclic nitrile. The use of the cata... | 04/01/2003 |
| 6485886 | Oxime derivatives and the use thereof as latent acids New oxime derivatives of formula (I) or. (II), wherein m is 0 or 1; R1 inter alia is phenyl, naphthyl, anthracyl, phenanthryl or a heteroaryl radical; R'1 is for example C2 -C12 alkylene, phenylene, naphthylene;... | 11/26/2002 |
| 6448416 | Electron acceptors for polymeric thin film waveguide media The present invention is directed to dicyanomethylenedihydrofuran-based electron acceptors which can be used in the preparation of polymeric thin films for waveguide media, and methods of making the same.... | 09/10/2002 |
| 6444830 | Electron acceptors for polymeric thin film waveguide media The present invention is directed to dicyanomethylenedihydrofuran-based electron acceptors which can be used in the preparation of polymeric thin films for waveguide media, and methods of making the same.... | 09/03/2002 |
| 6339161 | Group 8, 9 or 10 transition metal catalyst for olefin polymerization Olefin co- or homopolymers having a good molecular weight and short chain branching may be prepared in the presence of a tridentate complex of a Group 8, 9 or 10 metal.... | 01/15/2002 |
| 6265428 | Substituted phenyl compounds and derivatives thereof that modulate the activity of endothelin Methods, compositions, and compounds for modulating the activity of an endothelin peptide are provided. The methods use compositions that contain compounds of formula (1): ##STR1## where X and Y are selected from groups that include O, S, and NH; and ... | 07/24/2001 |
| 6248773 | Cyclopentane heptan(ene)oic acid, 2-heteroarylalk(en)yl derivatives as therapeutic agents The invention relates to the use of cyclopentane heptan(ene)oic acid, 2-heteroarylalk(en)yl derivatives as ocular hypotensives. The compounds used in accordance with the invention are represented by the following formula I: ##STR1## wherein the hatch... | 06/19/2001 |
| 6166074 | Pharmaceutical compositions Pharmaceutical compositions which are useful for the treatment of cancer or illnesses which arise due to an abnormally elevated cell proliferation comprise acyl derivatives of aromatic aldehydes, especially arylidene diesters and -alkoxyarylidene e... | 12/26/2000 |
| 6160129 | Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents The invention relates to the use of derivatives of F-type prostaglandins as ocular hypotensives. The compounds used in accordance with the invention are represented by the following formula I: ##STR1## wherein wavy line attachments indicate either th... | 12/12/2000 |
| 6153759 | Heterocyclic benzoyl intermediates for herbicidal compounds Heterocyclic substituted benzoyl derivatives of the formula ##STR1## where Z is a 5-membered or 6-membered heterocyclic, saturated or unsaturated radical containing one to three hetero atoms selected from the group consisting of oxygen, sulfur and ni... | 11/28/2000 |
| 6150397 | 5-aroylnaphthalene derivatives as anti-inflammatory agents The present invention relates to certain 5-aroylnaphthalene derivatives of formula (I): ##STR1## that are inhibitors of prostaglandin G/H synthase, pharmaceutical compositions containing them, methods for their use, and methods for preparing the... | 11/21/2000 |
| 6124344 | Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents The invention relates to the use of derivatives of F-type prostaglandins as ocular hypotensives. The compounds used in accordance with the invention are represented by the following formula I: ##STR1## wherein wavy line attachments indicate either th... | 09/26/2000 |
| 6063928 | 5-lipoxygenase inhibitors Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: ##STR1## and the pharmaceutically acceptable salts thereof, wherein Ar1 is a heterocyclic moiety which is selected from imidazolyl, pyr... | 05/16/2000 |
| 6057342 | Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof The present application describes amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein one of D and D' may be C(.dbd.NH)NH2 a... | 05/02/2000 |
| 6057319 | 3,4-Diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors The invention encompasses the novel compound of formula (I) useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising co... | 05/02/2000 |
| 6005113 | Long wavelength dyes for infrared tracing The invention relates to fluorescent dyes that are substituted or unsubstituted derivatives of 1-(isoindolyl)methylene-isoindole that are bound through both isoindole nitrogens to a boron difluoride moiety, forming a fluorescent dibenzopyrrometheneboron d... | 12/21/1999 |
| 5922767 | Substituted benzylurea derivatives and medicine containing the same Disclosed herein are substituted benzylurea derivatives represented by the following general formula (1): ##STR1## wherein R1 and R2 are independently H, a halogen atom, or an alkyl or alkoxyl group, R3 is a phenyl or... | 07/13/1999 |
| 5883106 | 5-lipoxygenase inhibitors Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: ##STR1## and the pharmaceutically acceptable salts thereof, wherein Ar1 is a heterocyclic moiety which is selected from imidazolyl, pyr... | 03/16/1999 |
| 5824691 | Guanidine derivatives as inhibitors of Na+ /H+ exchange in cells Guanidine derivatives of the formula: ##STR1## wherein Y is C--R1 (in which R1 is hydrogen, lower alkyl, hydroxy, protected hydroxy, etc.,) R2 is pyrrolyl, tetrazolyl, pyrazolyl, etc., R3 is hydrogen, lower alko... | 10/20/1998 |
| 5693667 | Fungicides for the control of take-all disease of plants A compound, composition, and method for controlling Take-all disease of plants by applying a fungicide of the formula: ##STR1## wherein Z1 and Z2 are carbons of a furan ring; A is selected from the group consisting of --C(X)-ami... | 12/02/1997 |
| 5665763 | Therapeutic phenoxyalkylpyridazines and intermediates therefor Compounds of the formula ##STR1## wherein: R1, R2, R3 and R4 are as defined in the specification, Y is alkylene of 3 to 9 carbon atoms, R5 is alkoxycarbonyl, alkyltetrazolyl, phenyl or a heterocycle c... | 09/09/1997 |
| 5591833 | Colorants and intermediates therefor having branched poly(oxyalkylene)moieties, and their manufacture Colorants and compositions useful as a fugitive or permanent colorant for a variety of substrates, or as intermediates for their manufacture, and having one or more improved properties of enhanced aqueous washability, compatibility with and non-extractibi... | 01/07/1997 |
| 5514642 | Cyclohexenone oxime ethers, their preparation and their use Cyclohexenone oxime ethers of the formula I ##STR1##... | 05/07/1996 |
| 5506243 | Sulfonamide derivatives Since sulfonamide derivatives of the present invention show strong inhibitory activity against cysteine protease such as calpain papain, cathepsin B, cathepsin H, cathepsin L, they can be used as remedies for muscular dystrophy, cataract, myocardial infar... | 04/09/1996 |
| 5416235 | Preparation of substituted aryl compounds A process for the preparation of aromatic compounds of the general formula I, Ar--X I in which Ar represents an optionally substituted aryl group and X represents a group OH, Cl, Br or CN, by reaction of an ... | 05/16/1995 |
| 5387747 | Triazolopyrimidine derivatives which are angiotensin II receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present The present invention relates to the derivatives of the formula ##STR1## and their tautomeric forms, as well as their addition salts, and to their use in therapeutics, especially for the treatment and prevention of cardiovascular diseases and in part... | 02/07/1995 |
