Bizarre Patents
Pneumatic Shoe Lacing Apparatus
This invention provides a pneumatic shoe lacing apparatus for the pneumatic lacing of shoe.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8138360 | Isotopically-labeled benzofuran compounds as imaging agents for amyloidogenic proteins Benzofuran compounds which contain at least one detectable label selected from the group consisting of 131I, 123I, 124I, 125I, 76Br, 75Br, 18F, 19F, 11C, 13... | 03/20/2012 |
| 7683190 | Process for the preparation of optically-active compounds A method of preparing enatiomerically enriched 3a,6,6,9a-tetramethyl-dodecahydro-naphtho[2,1-b]furan, formula (I), from (E,E)-homofarnesic acid or (E)-monocyclohomofarnesic acid by (a) reacting firstly with a chiral alcohol, (b) reacting the product of (a) with an a... | 03/23/2010 |
| 7435838 | Crystalline citalopram diol intermediate alkali The present invention relates to the diol intermediate of citalopram useful for treatment of depression, which is the crystal of free base of 3-hydroxylmethyl-4-[1-(4-fluorophenyl)-1-hydroxyl-4-(dimethylamino)]butylbenzonitrile and the method of crystallization ther... | 10/14/2008 |
| 7420070 | Process for preparing optically active 2,3-dihydrobenzofuran compounds A process for preparing optically active 2,3-dihydrobenzofuran compounds which comprises subjecting a 2,3-dihydrobenzofuran compound represented by the general formula or a salt thereof to optical resolution with an optically active acid compound: ... | 09/02/2008 |
| 7390913 | Process for the preparation of racemic citalopram diol and/or - or -citalopram diols and the use of such diols for the preparation of racemic citalopram, -citalopram and/or -citalopram In the following, citalopram diol means 4-(4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile, as free base and/or acid addition salt. The invention relates to a process for the preparation of racemic citalopram diol and/or R- or S-c... | 06/24/2008 |
| 7371774 | Benzofurans and benzothiophenes The invention relates to compounds of the general formula (I) below: in which R1, R2, R3, R4, R5, R6 and X are as defined in claim 1. These compounds can be used in the treatment of pathologies associated wi... | 05/13/2008 |
| 7368476 | Hydroxamates as therapeutic agents The present invention is directed to certain hydroxamate derivatives that are inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparin... | 05/06/2008 |
| 7365196 | Sulphonamido-substituted bridged bicycloalkyl derivatives A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease. ... | 04/29/2008 |
| 7358248 | Substituted amino carboxylic acids Disclosed are compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of... | 04/15/2008 |
| 7345068 | Aromatic amino acid derivatives and medicinal compositions 1. An aromatic amino acid derivative represented by the formula (I) or its pharmacologically acceptable salt: wherein, R1 is a hydrogen atom or an amino-protecting group, ... | 03/18/2008 |
| 7323577 | Process for producing benzofuran derivative A novel process for efficiently and easily producing a compound represented by the formula: wherein ring A is a benzene ring that may be optionally further substituted in addition to the group represented by W, o... | 01/29/2008 |
| 7291184 | Method of reducing the organic carbon content of production waste water in the course of the preparation of concentrated solutions of anionic organic compounds The present invention relates to a method of reducing the total organic carbon (TOC) content of waste water in the course of the preparation of concentrated solutions or suspensions of anionic organic compounds, which method comprises increasing the concentration of... | 11/06/2007 |
| 7265152 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections ... | 09/04/2007 |
| 7211694 | Substituted 4-aminocyclohexanols Substituted 4-aminocyclohexanols, processes for their preparation, pharmaceutical compositions comprising these compounds and to the use of substituted 4-aminocyclohexanols in the preparation of pharmaceutical compositions for the treatment of various indications, e... | 05/01/2007 |
| 7183436 | Substituted 4-aminocyclohexanols Substituted 4-aminocyclohexanols, methods of producing the same, pharmaceuticals containing these compounds, the use of substituted 4-aminocyclohexanols for producing pharmaceutical compositions for the treatment of various indications, in particular pain, and for r... | 02/27/2007 |
| 7173061 | Compounds for imaging alzheimer's disease The invention provides compounds of formula (I) or a salt thereof, radiolabelled versions thereof, and their use in the diagnosis or in vivo imaging of Amyloid-associated diseases such as Alzheimer's disease ... | 02/06/2007 |
| 7148254 | 2-Phenylbenzofuran derivatives, a process for preparing them, and their use The present invention relates to 2-phenylbenzofurans of formula (I) which are formed, during fermentation, by the microorganism Aspergillus flavipes ST003878 (DSM 15290), to a process for preparing them and to th... | 12/12/2006 |
| 7144893 | 4-aryl quinols and analogs thereof as therapeutic agents The present invention pertains to compounds of the formula (1) which are, inter alia, antiproliferative agents, anticancer agents, antimycobacterial agents, antituberculosis agents, and/or thioredoxin/thioredoxin reductase inhibitor: wherein: Q is ═O or ═N—S(... | 12/05/2006 |
| 7144881 | Arylcyclopropylcarboxylic amides as potassium channel openers The present invention provides novel arylcyclopropylcarboxylic amides and related derivatives having the general Formula I wherein R, R1, R2, R3, R4, R5, R | 12/05/2006 |
| 7138533 | Preventives/remedies for urinary disturbance Preventives/remedies for voiding disturbance containing a compound having both of an acetylcholinesterase inhibitory action and an α1 antagonistic action which exhibits an excellent effect of improving the urinary function of the bladder (i.e., effects of improving... | 11/21/2006 |
| 7132445 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disor... | 11/07/2006 |
| 7129268 | Peroxisome proliferator activated receptor-active arylene acetic acid derivatives Novel compounds of the general formula (I), wherein Ar, R1, R2, X1, X2, Y1, Y, and Z are as defined in the specification, the use of these compounds as pharm... | 10/31/2006 |
| 7122228 | Compound having negative Δε The invention relates to indanes having negative Δε of the formula Ia or Ib in which R, A, Z, X, Y, V, W, n and m are as defined in claim 1. The compounds are particularly suitable for producing VA-TFT ... | 10/17/2006 |
| 7119215 | Production method of citalopram, intermediate therefor and production method of the intermediate A compound of formula [V] is prepared by oxidizing a compound of formula [III]. Citalopram can be industrially and economically produced and at a high yield by converting a compound of formula [V], which is prepared from a compound of formula [III], to a compound of... | 10/10/2006 |
| 7112686 | Process for the preparation of racemic citalopram and/or S-or R-citalopram by separation of a mixture of R-and S-citalopram The invention relates to a process for the preparation of racemic citalopram free base or an acid addition salt thereof and/or R- or S-citalopram as the free base or an acid addition salt thereof by separation of a mixture of R- and S-citalopram with more than 50% o... | 09/26/2006 |
| 7101867 | Benzofuran derivatives, their production and use Compounds represented by the formula: wherein R1 and R2 are hydrogen atom, a hydrocarbon group or a heterocyclic group, or R1 and R2 may form, together with the adjacent carb... | 09/05/2006 |
| 7084136 | Drug composition antagonistic to both PGD/TXA receptors A compound of the formula (I): wherein A is alkylene optionally having an unsaturated bond; R is —C(═O)—R1; R1 is hydroxy or the like; m is 0 or 1; p is 0 or 1; X1 and X | 08/01/2006 |
| 7078541 | Benzofuran derivatives Certain benzofuran derivatives are useful in the treatment of certain ischemic or inflammatory conditions, as well as neuroinflammation, neurodegeneration or degenerative diseases in which mitochondrial dysfunction leads to tissue degeneration. They are also useful ... | 07/18/2006 |
| RE39197 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.... | 07/18/2006 |
| 7071227 | Antiviral compositions and methods of use Purified antiviral compounds, pharmaceutical formulations containing the compounds, and methods of use of the compounds are provided. The compositions of the invention are isolated antiviral components from plant extracts derived from, for example, Salvia miltior... | 07/04/2006 |
| 7060109 | Hair dyeing agents containing indigo derivatives Compositions and method for coloring keratin fibers consisting of derivatives of benzo[b]furan-3-one and/or benzo-[b]-thiophen-3-one compounds with special reactive components. These compositions form intensely colored compounds when applied to keratin fibers. The c... | 06/13/2006 |
| 7034166 | Process for producing benzofuran derivative A novel process for efficiently and easily producing a compound represented by the formula: wherein ring A is a benzene ring that may be optionally further substituted in addition to the group represented by W, or a sal... | 04/25/2006 |
| 7030239 | Compounds to treat Alzheimer's disease The present invention is directed toward substituted hydroxyethylene compounds of formula (XII) useful in treating Alzheimer's disease and other similar diseases. ... | 04/18/2006 |
| 7019003 | Peptide deformylase inhibitors Novel PDF inhibitors and novel methods for their use are provided. ... | 03/28/2006 |
| 7008950 | Benzofurans as suppressors of neurodegeneration A compound of the formula: wherein R1 and R2 each is H or a hydrocarbon group which may be substituted, or R1 and R2 form a 3- to 8-membered carbo or heterocyclic ring which ... | 03/07/2006 |
| 7005448 | Aminoalkyl-benzofuran-5-ol compounds for the treatment of glaucoma The present invention provides novel compounds, compositions containing the compounds of the invention in a pharmaceutically acceptable excipient and methods for using the compositions for lowering intraocular pressure. ... | 02/28/2006 |
| 7002025 | Process for the preparation of citalopram Preparation of citalopram comprises the steps of: (a) converting the compound of Formula (I) to a compound of Formula (II), wherein R in Formula (I) represents a C2 to C5 alkylene group which may be substituted or unsubstituted, and R1 | 02/21/2006 |
| 6987194 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives of Formula I are disclosed. These compounds provide unexpected insecticidal activity across a spectrum of insect pests combined with desirable physical properti... | 01/17/2006 |
| 6969730 | Amines as histamine-3 receptor ligands and their therapeutic applications Compounds of formula (I) or a pharmaceutically acceptable salts or prodrug thereof which are useful for the modulation of the histamine-3 receptors in mammals and which are useful for the treatment of disorders amelior... | 11/29/2005 |
| 6946564 | Production method of an intermediate for citalopram Citalopram can be industrially and economically produced and at a high yield by reacting a compound of the following formula [VI] with 3-(dimethylamino)propyl chloride in the presence of at least one of N,N,N′,N′-tetramethylethylenediamine and 1,3-dimethyl-2-imi... | 09/20/2005 |
