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| Number | Title | Issue Date |
| 7947846 | 15-OXA-steroid compounds The invention relates to the use of compounds to treat a number of conditions, such as thrombocytopenia, neutropenia or the delayed effects of radiation therapy. Compounds that can be used in the invention include methyl-2,3,4-trihydroxy-1-O-(7,17-dioxoandrost-5 -en... | 05/24/2011 |
| 7420065 | Hetero-polycyclic compounds, and coloring matters, pigments, dyes, color-changing material compositions, and color-changing films, made by using the compounds Provided are novel hetero-polycyclic compounds having a specific structure, color-changing material compositions comprising (A) a fluorescent coloring matter comprising at least one of the hetero-polycyclic compounds described above and (B) a binder material, color-... | 09/02/2008 |
| 7408072 | Heteropolycyclic compound and dye The present invention provides heteropolycyclic compounds represented by General Formulae (1) and (2): wherein R1 is a straight- or branched-chain C1-C10 alkyl group or the like; R2 | 08/05/2008 |
| 7317115 | Mandelates salts of substituted tetracyclic tetrahydrofuran derivatives The object of the present invention is a novel mandelate salt of a substituted tetracyclic tetrahydrofuran derivative according to Formula (I) the N-oxide forms and the stereochemically isomeric forms thereof, wh... | 01/08/2008 |
| 7253292 | Synthesis of cyclopentadiene derivatives A process for preparing cyclopentadiene derivatives comprising the steps of: a) coupling a five membered heterocycle ring with a five or six membered heterocycle ring; b) reacting the obtained compound with a carbonilating system: c) reducing the obtained compound. | 08/07/2007 |
| 7205335 | Preparation of cis-fused 3,3a,8,12b-tetrahydro-2H-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives The present invention concerns a process for preparing each of the 4 individual diastereomers of formula (I) in stereochemically pure form from a single enantiomerically pure precursor. The tetracyclic ringsystem having cis-fused five and seven membered rings is for... | 04/17/2007 |
| 7053225 | Intermediates and improved processes for the preparation of neplanocin A Intermediate compounds, including 2-(t-butyldimethylsilyloxymethyl)-3,4-[(dimethylmethylene)dioxy]-5-hydroxy-tricyclo[5.2.1.02,6]dec-8-ene, which are useful for the synthesis of neplanocin A having strong antitumor activity. Improved processes for the pre... | 05/30/2006 |
| 7053224 | Intermediates and improved processes for the preparation of neplanocin A Intermediate compounds, including 2-(t-butyldimethylsilyloxymethyl)-3,4-[(dimethylmethylene)dioxy]-5-hydroxy-tricyclo[5.2.1.02,6dec-8-ene, which are useful for the synthesis of neplanocin A having strong antitumor activity. Improved processes for the prep... | 05/30/2006 |
| 7049308 | C-nitroso compounds and use thereof A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less th... | 05/23/2006 |
| 7026021 | Fluorinated heterocycles and their use in liquid-crystal mixtures Compounds of the general formula (I) where: R1, R2 are each independently a) H b) -M1-A1-R5 | 04/11/2006 |
| 6998494 | Preparation of trans-fused 3,3a,8,12b-tetrahydro-2h-dibenzo[3,4:6,7]cyclohepta[1,2-b]furan derivatives The present invention concerns processes for the preparation of each of the 4 diastereomers of formula (I) in stereochemically pure form from either of two enantiomerically pure precursors. The tetracyclic ringsystem ha... | 02/14/2006 |
| 6955838 | Fluorinated polycycles and their use in liquid-crystal mixtures Compounds of the formula (I) where: R1, R2 are each independently a) H b) -M1-A1-R5 ... | 10/18/2005 |
| 6930190 | Process for the preparation of heterocyclic pentalene derivatives A process for preparing heterocyclic pentalene derivative having formula (I): wherein w is a sulfur atom (S), an oxygen atom (O) or a NR or PR group, wherein R is an hydrocarbon group; R1, R2, R3, and R4, equal to or diffe... | 08/16/2005 |
| 6861537 | Tricyclic and tetracyclic taxane intermediates The synthesis of taxol and other tricyclic and tetracyclic taxanes. ... | 03/01/2005 |
| 6545167 | Simple and effective manufacturing process for large scale recovery of Nimbin, a Neem seed constituent Methods are disclosed for the large-scale isolation of 98.5% pure Nimbin from Neem seeds. The ultimate product is obtained first from an alcoholic extraction with subsequent partitioning using chlorinated hydrocarbon solvents. A resulting partitioned laye... | 04/08/2003 |
| 6284789 | Formation and composition of new optically active compounds The present invention is directed to tetrahydronaphthalene derivatives of -conindendrin, ଲ-conindendrin, sikkimotoxin, and podophyllotoxin having at least one methyleneoxy bridge wherein the oxygen atom extends to the benzhydrylic carbon atom... | 09/04/2001 |
| 6113812 | Photochromic articles A photochromic article that includes a host material and a photochromic amount of a benzopyran compound, the benzopyran compound represented by one of the formulas: ##STR1## wherein R1, R2, R3, R4, R5 | 09/05/2000 |
| 6110962 | 11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia This invention provides compounds of Formula I having the structure ##STR1## wherein A is hydrogen, halogen, or OH; B and D are each, independently, hydrogen, halogen, CN, alkyl of 1-6 carbon atoms, aryl, aralkyl of 6-12 carbon atoms, nitro, amino or OR; ... | 08/29/2000 |
| 6083980 | Furanyl, tetracyclic triterpene derivatives with immunosuppressant activity The compounds of Formula I ##STR1## are useful as immunosuppressive agents.... | 07/04/2000 |
| 5981574 | Phenanthrofuran derivatives Phenanthrofuran derivatives and methods of using them to treat angiogenic diseases.... | 11/09/1999 |
| 5754271 | Heterocyclic chromenes and their use in the field of ophthalmic optics The invention relates to photochromic compounds of general formula: ##STR1## wherein Ra, Rb and Rc is denote hydrogen; alkyl; aryl; OR, SR, COR or COOR, in which R denotes hydrogen, alkyl or aryl, amino of formula NR | 05/19/1998 |
| 5744070 | Photochromic substituted naphthopyran compounds Described are novel reversible photochromic naphthopyran compounds, examples of which are 3H-naphtho2,1-b!pyrans having an acyl or aroyl oxy-bearing substituent at the number 6 carbon atom and certain substituents at the 3-position of the pyran ring. Ce... | 04/28/1998 |
| 5702710 | Dibenzofuran compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active dibenzofuran compounds have the structural formula (I): ##STR1## wherein A is a radical having one of the formulae (IIa), (IIb) or (IIc): ##STR2## and are useful for the treatment of a wide variety of d... | 12/30/1997 |
| 5614548 | Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions Quaternary amine-containing ether lipid analogs of the formula R1 --X--R2 --N+ (R3) (R4) (R5) Z- are disclosed. R1 represents a hydrophobic group and R2 represents th... | 03/25/1997 |
| 5612356 | Heterocycle-containing carbonic acid derivatives A heterocycle-containing carbonic acid derivative represented by the following general formula (I): ##STR1## or a physiologically acceptable salt thereof which exhibits an excellent preventive and therapeutic effect against various diseases, and an ... | 03/18/1997 |
| 5552091 | Benzopyran compounds Described are novel reversible photochromic benzopyran compounds, examples of which are compounds substituted at the 2-position of the pyran ring with a dibenzo-fused 5 member heterocyclic compound; other enumerated substituents at the other 2-position of... | 09/03/1996 |
| 5429774 | Benzopyran compounds Described are novel reversible photochromic benzopyran compounds, examples of which are compounds having the 2,3 position of a benzofurano or benzothieno group fused to the f, g, or h side of the benzopyran, or a benzo group fused to the f side of the ben... | 07/04/1995 |
| 5422365 | Naphthalene compounds A compound selected from those of formula (I): ##STR1## wherein: R1, R'1 and R2 are each selected, independently of the others, from hydrogen and an alkyl radical, the two R2 groups being in the cis positio... | 06/06/1995 |
| 5411679 | Benzopyrans Described are novel reversible photochromic benzopyran compounds, examples of which are compounds substituted at the 2 position of the pyran ring and have fused at the benzo portion of the benzopyran a substituted or unsubstituted heterocyclic ring such a... | 05/02/1995 |
| 5338758 | Bicyclic diterpene PAF antagonist compounds Four bicyclic terpenes isolated from a culture broth of Phoma sp SCF0592, ATCC 74077, pharmaceutical compositions containing them and their use as PAF antagonists to treat allergic and inflammatory diseases are disclosed.... | 08/16/1994 |
| 5276053 | Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.... | 01/04/1994 |
| 5084579 | Benzofuran compounds A benzofuran compound of the formula ##STR1## wherein A represents ##STR2## wherein R1, R2, R3, B and D have various meanings. The benzofuran compound is usefully employed in pharmaceutical and cosmetic comp... | 01/28/1992 |
| 5075331 | Benzofuran compounds, compositions containing them and processes for using the compositions A benzofuran compound of the formula ##STR1## wherein A represents ##STR2## wherein R1, R2, R3, B and D have various meanings. The benzofuran compound is usefully employed in pharmaceutical and cosmetic comp... | 12/24/1991 |
| 5071853 | Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.... | 12/10/1991 |
| 4978679 | 6- and/or 7-substituted-1,2,3,4,4A,9B-hexahydro-8-hydroxydibenzofuran-3-ols as inhibitors of leukotriene biosynthesis Positions 7- and/or 6-substituted 1,2,3,4,4a,9b-Hexahydro-8-hydroxydibenzofuran-3-ols and analogs of that general structure are described. These compounds are found to be potent inhibitors of 5-lipoxygenase, an enzyme crucial to the biosynthesis of leukot... | 12/18/1990 |
| 4935532 | Hemiacetals All possible isomeric forms of a compound of the formula ##STR1## wherein A has a structure selected from the group consisting of ##STR2## wherein Y1 and Y2 are individually selected from the group consisting of hydrogen, f... | 06/19/1990 |
| 4918101 | Tetracyclic phenanthro furan heterocyclic derivatives compositions and use The present invention relates to antitumor compounds of formula (I) ArCH2 R1 (I) or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 29... | 04/17/1990 |
| 4857516 | Coumaran derivatives and their pharmaceutical use A compound of the formula ##STR1## wherein R is a lower alkyl group, R0 is hydrogen or an acyl group, R1 and R2 are lower alkyl groups which may optionally be substituted or wherein R1 and R2 are... | 08/15/1989 |
| 4801607 | Antiviral furanoditerpenoids This invention relates to antitumor and antiviral furanoditerpenoid compositions, a process of producing the compositions and a method for inhibiting tumors and viruses utilizing the compositions. More particularly, the new compositions are antitumor and ... | 01/31/1989 |
| 4788305 | Novel resolution process Compounds of the formula ##STR1## wherein A is a hydrocarbon chain containing 1 to 16 groups, the said chain containing at least one heteroatom, at least one unsaturation, the assembly of the group constituting the chain may be a mono- or polycyclic ... | 11/29/1988 |
