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| Number | Title | Issue Date |
| 7345181 | Process for preparing prostaglandin derivatives and starting materials for the same The present invention provides a process for preparing benzoprostacycline derivatives of formula (1), i.e. 5,6,7-trinor-4,8-inter-m-phenylene PGI2 derivatives, and vinyl tin compounds of formula (III) as starting materials for the same. ... | 03/18/2008 |
| 7259266 | Benzopyran compounds useful for treating inflammatory conditions The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 | 08/21/2007 |
| 7138427 | 5-β-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed ... | 11/21/2006 |
| 7138411 | Substituted benzopyran derivatives for the treatment of inflammation A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I′ | 11/21/2006 |
| 7122685 | Dibenzoanthraquinone based chromophores An infrared dye, characterized in that the dye comprises a compound that comprises a molecule that can be described by claim 1. ... | 10/17/2006 |
| 7018430 | Method of mass-coloring synthetic materials The present invention relates to a method of mass-coloring synthetic materials, which comprises using at least one pigment dye of formula (1) wherein R and R1 together form a phenyl or heteroaryl radical and R2 is hydrogen, or R1 and... | 03/28/2006 |
| 6930188 | Stable hydrate of a muscarinic receptor antagonist A stable solid hydrate of a muscarinic receptor antagonist is useful in the treatment of irritable bowel syndrome, diverticular disease, oesophageal achalasia, chronic obstructive airways disease, over active bladder (including symptoms of incontinence, urge and fre... | 08/16/2005 |
| 6864225 | Cyclic ketals, fragrance compositions containing the same and methods of using the same Compounds of the general formula (I) are described: wherein each of R1, R2, R3, R4, R5 and R6 independently represents a substituent selected from the g... | 03/08/2005 |
| 6794408 | Drechsleranol derivatives, processes for their preparation and their use The present invention provides novel drechsleranol compounds of formula (I) which are formed by the microorganism Drechslera australlensis, ST 003360, DSM 14093, or a fungus ST 004112, DSM 14524, during fermentation. A process for their preparation, pharmaceu... | 09/21/2004 |
| 6716987 | Derivatives of benzofuran or benzodioxazole compounds An oxygen-containing heterocyclic compound represented by following Formula (I): wherein R1 and R2 independently represent hydrogen, lower alkyl, cyano, —(CH2)n—E1 | 04/06/2004 |
| 6703084 | Quinone compound, liquid crystal composition, and guest-host-type liquid crystal cell employing the same A quinone compound represented by formula (1) or (2) below: ##STR1## (wherein X1 to X4 independently represents an oxygen atom, sulfur atom or N--R1 ; R1 represents a hydrogen atom, alkyl group, aryl group or he... | 03/09/2004 |
| 6686348 | Metalloprotease inhibitors A compound of formula (I): ##STR1## wherein: R1 represents hydrogen, halogen, alkyl or alkoxy, X represents oxygen, sulphur or NR wherein R represents hydrogen or alkyl, A represents any one of the groups described in the description, their isomers and a... | 02/03/2004 |
| 6642217 | Triterpenes having human antifungal and antiyeast activity Methods of treating a fungal or yeast infection and of killing or inhibiting fungi or yeast are disclosed. The methods use derivatives of triterpenes that are abundant in birch bark and other plants. The triterpenes include betulin, allobetulin, and lupeo... | 11/04/2003 |
| 6579328 | Transition-metal-catalyzed process for the preparation of sterically hindered N-substituted aryloxyamines Sterically hindered N-substituted aryloxyamines are prepared by the transition-metal-catalyzed decomposition of diazonium salts in the presence of a sterically hindered nitroxyl radical. These compounds are useful as thermal and light stabilizers for a va... | 06/17/2003 |
| 6547841 | Transition-metal-catalyzed process for the preparation of sterically hindered N-substituted alkoxy amines Sterically hindered N-substituted alkoxyamines are prepared by the transition-metal-catalyzed decomposition of diazonium salts in the presence of a sterically hindered nitroxyl radical. These compounds are useful as thermal and light stabilizers for a var... | 04/15/2003 |
| 6548537 | Triptolide prodrugs having high aqueous solubility Compounds useful in immunosuppressive, anti-inflammatory and anticancer treatment are described. The compounds are triptolide analogs with improved water solubility and generally lower toxicity than the parent compound.... | 04/15/2003 |
| 6514996 | Derivatives of benzofuran or benzodioxole An oxygen-containing heterocyclic compound represented by following Formula (I): ##STR1## wherein R1 and R2 independently represent hydrogen, lower alkyl, cyano, --(CH2)n --E1 --CO--G1 (whe... | 02/04/2003 |
| 6444709 | Heteroethylene compounds and pharmaceutical and cosmetic compositions containing same The invention relates to novel heteroethynylenic compounds having the general formula (I): ##STR1## as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, r... | 09/03/2002 |
| 6410754 | Photochromic spiropyrans, and compositions and articles containing same Novel spiropyran compounds, particularly with photochromic properties, are disclosed, as well as photochromic compositions and ophthalmic articles containing said compounds. The photochromes have been designed so as to have a high colorability, a high sen... | 06/25/2002 |
| 6399779 | Aryl borates The invention provides a process for covalently coupling organic compounds which comprises reacting an aromatic ring compound having a halogen substituent or other substituent which undergoes substitution with a diboronic acid ester at a coupling position... | 06/04/2002 |
| 6369101 | Therapeutic method to treat herpes virus infection A therapeutic method is provided for treating a mammal afflicted with a herpesvirus infection, comprising administering an effective amount of a compound of formula I: ##STR1## wherein R1 -R11, have any of the values disclosed in the... | 04/09/2002 |
| 6297363 | Glycoside indoles The present invention relates to a novel class of glycoside indoles. More specifically, the present invention relates to a novel class of glycoside indoles isolated from Calanthe discolor Lindl. and derivatives thereof.... | 10/02/2001 |
| 6284789 | Formation and composition of new optically active compounds The present invention is directed to tetrahydronaphthalene derivatives of -conindendrin, ଲ-conindendrin, sikkimotoxin, and podophyllotoxin having at least one methyleneoxy bridge wherein the oxygen atom extends to the benzhydrylic carbon atom... | 09/04/2001 |
| 6150539 | Triptolide prodrugs having high aqueous solubility Compounds useful in immunosuppressive and anti-inflammatory treatment are described. The compounds are hydrolyzable triptolide analogs with improved water solubility and generally lower toxicity than the parent compound.... | 11/21/2000 |
| 6046233 | Agent for treating cor pulmonale The present invention relates to an agent for treating cor pulmonale containing as an active ingredient a prostaglandin I2 derivative represented by the following formula, or a pharmacologically acceptable salt thereof. The agent exhibits excel... | 04/04/2000 |
| 6034256 | Substituted benzopyran derivatives for the treatment of inflammation A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' ##STR1## wherein X, A1, A2, A3, A4, R, R",... | 03/07/2000 |
| 6028101 | Fungicides for the control of take-all disease of plants A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula ##STR1## wherein Z1 and Z2 are C and are part of an aromatic ring that is furan; A is selected ... | 02/22/2000 |
| 5972997 | UCT1072 compounds The present invention relates to UCT1072 compounds represented by formula (I): wherein R1 and R2 together represent --CH(OH)CH2 O-- or --CH2 CH2 CH(OH)CH2 --.... | 10/26/1999 |
| 5965718 | Analogs of sarcodictyin and eleutherobin Sarcodictyin A and B, eleutherobin, and bioactive analogs thereof synthesized using solid phase and solution phase chemistries. The synthetic method employs an attachment of common precursors, e.g., compounds 1880 or 200, on a solid support for generating... | 10/12/1999 |
| 5952371 | Triterpene derivatives with immunosuppressant activity The compounds of Formula I ##STR1## are useful as iumnunosuppressive agents.... | 09/14/1999 |
| 5874594 | Triterpene derivatives with immunosuppressant activity | 02/23/1999 |
| 5728849 | Taxoids their preparation and pharmaceutical compositions containing them New taxoids of general formula (I): ##STR1## wherein Z represents a hydrogen atom or a radical of general formula: ##STR2## in which R1 represents an optionally substituted benzoyl radical, a thenoyl or furoyl radical or a radical R | 03/17/1998 |
| 5663379 | Substituted phenyl ethers Compounds of the formula ##STR1## in which R1, R2, R3, R4, R5 and R6 are as defined in claim 1 can be used as agrochemical active ingredients and can be prepared in a manner known per ... | 09/02/1997 |
| 5635107 | Fluorine-containing five-membered ring compounds, and a liquid-crystaline medium containing them Fluorine-containing five-membered ring compounds of the formula I R1 -(A1 -Z1)m -A2 -Z2 -W I in which W is ##STR1## is a cyclohexane, cyclohexene or phenyl, Y1 is O or S, Y2 | 06/03/1997 |
| 5585505 | Hatching agent for the potato cyst nematode The invention is directed to a hatching agent for hatching the species and patho types of nematodes causing potation sickness, which nematodes comprise Globodera pallida, from the cysts thereof, with a molecular weight of 498, a component C27 H... | 12/17/1996 |
| 5290553 | Alkaloids of picralima nitida used for treatment of protozoal diseases A method of preparing substantially purified alkaloids from seeds, stems, uit-rind and bark of a plant selected from Picralima nitida, Gongronema latifolia, Dorstenia multiradiata, Cola attiensis, Rothmania withfieldii and Desmodium gangeticum, for use in... | 03/01/1994 |
| 5284870 | Aldose reductase inhibitor The present invention relates to an aldose reductase inhibitor represented by the formula: ##STR1## wherein R1 is (CH2)2 COOH and R2 is phenyl or p-hydroxyphenyl, or R1 and R2 are comb... | 02/08/1994 |
| 5276053 | Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.... | 01/04/1994 |
| 5122361 | Dopamine receptor ligands and imaging agents Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofur an, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain re... | 06/16/1992 |
| 5112977 | Substituted naphthacene-5,12-diones Substituted naphthacenediones of the formula I ##STR1## in which R1 to R8 are H and at least one of R1 to R8, for example R2 and R3 or R2 and R6, are, for example, ... | 05/12/1992 |
