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| Number | Title | Issue Date |
| 8026378 | Glyceryl ether compounds and their use Glyceryl ether compounds prepared by the reaction of glycerol and olefin epoxides are disclosed. The compounds are renewable biomass-based surfactants useful as detergents and emulsifiers in formulations for cleaning, laundry, personal care, cosmetics, and industria... | 09/27/2011 |
| 8013175 | Method of refining episesamin There is disclosed an episesamin refining method in which a mixture of sesamin components that contains sesamin, episesamin and the like is brought into contact with an aqueous medium to form a slurried mixture, and thereafter the solids are separated from the mixtu... | 09/06/2011 |
| 7326799 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing alpha-keto amide compound using them The present invention is to provide manufacturing intermediates which can be led to useful α-ketoamide compounds having protease-inhibiting activity extremely economically and stereoselectively, and to provide epoxycarboxamide compounds, azide compounds and amino a... | 02/05/2008 |
| 7294621 | Lipid analogs for combating tumors The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294620 | Lipid analogs for inhibiting HIV-1 activity The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294619 | Lipid analogs for inhibiting the activity of hepatitis B antigen The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7252710 | Pigment dispersion composition, use thereof and compound for pigment treatment A pigment dispersion composition which can be suitably applied in such fields as color filters, black matrices and ink jet recording where it is necessary to finely disperse pigments still with retention of good dispersion stability and temporal stability even when ... | 08/07/2007 |
| 7252886 | Curable composition and process for producing cured fluorinated product To provide a curable composition which gives a cured fluorinated product excellent in transparency, light resistance (particularly against a short wavelength light having a wavelength of from 200 to 500 nm) and heat resistance, and having a controlled volume particu... | 08/07/2007 |
| 7247735 | Octupolar molecules used as organic semiconductors In the case of the materials according to the invention, the charge carrier mobility in the correspondingly prepared films is achieved if the molecules are composed in such a way that side chains—consisting of conjugated aromatic or heteroaromatic systems—are at... | 07/24/2007 |
| 7220307 | Treated pigment, use thereof, and compound for pigment treatment A treated pigment and a dispersion composition thereof having preferable dispersion stability and fluidity in a dispersion medium even the pigment has no functional group reactive with a carbodiimide group on the surface thereof, and further to provide a resist comp... | 05/22/2007 |
| 7220306 | Treated pigment, use thereof, and compound for treating pigment The present invention provides a treated pigment produced by treating at least one pigment selected from the group consisting of organic pigments and carbon black each having a functional group reactive with a carbodiimide group with a carbodiimide compound h... | 05/22/2007 |
| 7199127 | Purine nucleosides Disclosed are purine nucleoside compounds that are selective to A3 adenosine receptors and are useful for the treatment of cancer and inflammatory diseases. The compounds are shown by the following general formula (I), including isomers thereof: | 04/03/2007 |
| 7129355 | Process for preparing kifunensine intermediate and kifunensine therefrom A novel method for the preparation of a compound of formula (I) from an N—protected-D-mannosamine. A compound of formula (I) is a useful intermediate for the preparation of kiftnensine, a potent and selective mannosidase inhibitor. The method includes protecting t... | 10/31/2006 |
| 6965034 | Synthesis of epothilones, intermediates thereto and analogues thereof The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates ... | 11/15/2005 |
| 6787559 | Sulfonamide compounds This invention relates to certain sulfonamide derivatives that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds. ... | 09/07/2004 |
| 6649652 | Prodrugs for antimicrobial amidines A methods of treating an infection comprises administering a therapeutically effective amount of a compound described by the Formula (I) ##STR1##... | 11/18/2003 |
| 6576776 | Method of manufacture of 1,3-oxathiolane nucleosides Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the process... | 06/10/2003 |
| 6503940 | Prodrugs for antimicrobial amidines A methods of treating an infection comprises administering a therapeutically effective amount of a compound described by the Formula (I): ##STR1## wherein: X may be O, S, or NR' wherein R' is H or loweralkyl, R1 and R2 may be indepen... | 01/07/2003 |
| 6492394 | Sulfonamide hydroxamates A compound of the Formula (I): ##STR1## wherein Z, R1, R, and Ar2 are as defined in the specification. This invention also relates to sulfonamide compounds of the Formula (I) that are inhibitors of procollagen C-proteinase, pharmaceu... | 12/10/2002 |
| 6486200 | Prodrugs for antimicrobial amidines A methods of treating an infection comprises administering a therapeutically effective amount of a compound described by the Formula (I): ##STR1## wherein: X may be O, S, or NR' wherein R' is H or loweralkyl; R1 and R2 may be indepen... | 11/26/2002 |
| 6437133 | Method of catalytically removing a protective group containing an allyl group using a reducing agent A method of efficiently removing the protective group from a protected hydroxyl or amino group with an allyl derivative by one step reaction under neutral conditions. A protected hydroxyl or amino group is converted into a free hydroxyl or amino group in ... | 08/20/2002 |
| 6383521 | Wondonin A and process for preparing the same The present invention provides Wondonin A of general formula (I), which is extracted from a two-sponge association of phylum Porifera (sponge) and has antiangiogenic activity, and a process for preparing the same. Wondonin A has no cytotoxicity, but has a... | 05/07/2002 |
| 6323238 | Benzopyranyl guanidine derivatives, process for preparation thereof, and pharmaceutical compositions containing them The present invention relates to novel benzopyranyl guanidine derivatives of the formula 1, process for preparation therof and pharmaceutical use of the benzopyranyl guanidine derivatives. The benzopyranyl guanidine derivatives of the present invention ca... | 11/27/2001 |
| 6284901 | Dinitrile intermediates for the synthesis of omapatrilat and methods for producing same Omapatrilat (I) is a potent inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) both in vitro and in vivo and is currently undergoing large scale clinical trials as an anti-hypertensive. Omapatrilat may be synthesized using th... | 09/04/2001 |
| 6211201 | Multivalent salts of pyridostigmine and related compounds A quaternary ammonium cholinergic agent is complexed with a multivalent anion, or with multiple monovalent anions. The complex may be administered orally to a patient to treat pain, or for some other purpose. Numerous modifications are contemplated, inclu... | 04/03/2001 |
| 6120859 | Polymerisable, optically active dioxolane diesters Polymerisable optically active compounds have the general formula: ##STR1## where: W1 denotes a polymerisable residue, S1 denotes a spacer unit, Y1 denotes a single bond, or one of the groups --O--, --COO--, --OOC--, --OCO... | 09/19/2000 |
| 6080862 | Stereoselective synthesis of endothelin receptor antagonists The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates ##STR1##... | 06/27/2000 |
| 6004957 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical ... | 12/21/1999 |
| 6001535 | Monomers with cyclic carbonate groups Monomers with cyclic carbonate groups of the formula I are suitable for the production of photosensitive recording materials, for example for the production of offset printing plates ##STR1## in which A means an (n+m)-valent hydrocarbon residue with ... | 12/14/1999 |
| 5869702 | Polyol ether derivatives and production methods therefor Polyol ether derivatives, a method for producing the polyol ether derivatives, and a working fluid composition for a refrigerating machine containing a hydrofluorocarbon and a refrigeration oil containing the polyol ether derivatives as a base oil.... | 02/09/1999 |
| 5801191 | Taxoids Novel taxoids are provided having enhanced water solubility and/or improved pharmacological properties as compared to paclitaxel. The subject taxoids comprise a functional group attached to a paclitaxel at the C-2' and/or C-7 position by a linking group. ... | 09/01/1998 |
| 5801258 | Amide derivatives and dermatologic preparations containing the same The amide derivative of the present invention is one represented by the following general formula (I) and the dermatologic preparation of the present invention is one containing said amide derivative. ##STR1## wherein R1 represents a strai... | 09/01/1998 |
| 5783701 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical ... | 07/21/1998 |
| 5750696 | Dioxacycloalkane compound having renin-inhibitory activity Dioxacycloalkane compounds of the formula 1! ##STR1## wherein A is ##STR2## wherein W is ##STR3## X is --CO-- or --SO2 --; Y is --CH2 --, --O-- or --NR25 --; and R1 is an aralkyl which may ... | 05/12/1998 |
| 5723646 | Substituted amino acid amide derivatives their preparation and use as fungicides There are described new amino acid amide derivatives, some of which are known, of the formula (I) ##STR1## in which R1 to R8 have the meaning given in the description, and a process for their preparation. The amino acid amide de... | 03/03/1998 |
| 5659052 | Amide derivatives and dermatologic preparations containing the same The amide derivative of the present invention is one represented by the following general formula (II) and the dermatologic preparation of the present invention is one containing said amide derivative. ##STR1## wherein R11 represents a str... | 08/19/1997 |
| 5618946 | 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same The present invention relates to novel 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates which may be used to prepare a final anti-thrombotic, anti-vasospastic product, and to methods for preparing the same.... | 04/08/1997 |
| 5602264 | Highly reactive, water soluble carbodiimides, intermediates and derivatives thereof Novel water soluble carbodiimides, and intermediates or derivatives thereof, such as isoureas or isothioureas, are described. A particularly preferred embodiment is bis[4-(2,2-dimethyl-1,3-dioxolyl)methyl] carbodiimide (BDDC), which can be synthesized eff... | 02/11/1997 |
| 5585397 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical ... | 12/17/1996 |
| 5585364 | Antiviral compounds Compounds of formula I or a pharmaceutically acceptable salt thereof: ##STR1## in which formula R1 represents an aliphatic hydrocarbyl group; Ar represents a substituted or unsubstituted aromatic nucleus; X represents --SO2 -- or --C... | 12/17/1996 |
