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| Number | Title | Issue Date |
| 7750169 | Process for the preparation of stiripentol particles having a defined particle size distribution The invention relates to a process for the preparation of stiripentol particles having a defined particle size distribution. ... | 07/06/2010 |
| 7183444 | Method for producing anis alcohol The present invention relates to a method for the preparation of anisalcohol (methoxybenzyl alcohol) by hydrogenation of anisaldehyde (methoxybenzaldehyde) in the presence of Raney nickel and a basic additive, the use of the anisalcohol and hygiene or care products ... | 02/27/2007 |
| 7019028 | Endiandric acid H and its derivatives, process for their preparation and use thereof The invention relates to compounds of the formula (I) process for their preparation starting from the plant Beilschmiedia fulva, PLA 101037, and the use thereof for producing a medicament, in particular for the t... | 03/28/2006 |
| 6864282 | 9,11-cycloendoperoxide pro-drugs of prostaglandin analogues for treatment of ocular hypertension and glaucoma 9,11-Cycloendoperoxide derivatives of biologically active prostaglandin analogs, and particularly of the ocular hypotensive drugs Bimatoprost, Latanaprost, Unoprostone, Travoprost and prostaglandin H2 1-ethanolamide or of structurally closely related anal... | 03/08/2005 |
| 6603024 | Process for the preparation of 3,4-methylenedioxymandelic acid A process for preparing 3,4-methylenedioxymandelic acid by reacting 1,2-methylenedioxybenzene with glyoxylic acid in the presence of a strong acid and of at least one substance selected from the group consisting of an aprotic organic solvent and 100 to 12... | 08/05/2003 |
| 6342613 | Process for the synthesis of 5-(-hydroxyalkyl) benzo[1,3]dioxols The present invention regards a three-step process for the synthesis of 5-(-hydroxyalkyl) benzo[1,3]dioxols. The process comprises: (i) the reaction of pyrocatechin (1,2-dihydroxybenzene) with a dihalo or di-alkoxyalkane, with the formation of a be... | 01/29/2002 |
| 6310080 | Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, rela... | 10/30/2001 |
| 6277867 | Pesticide compounds, compositions and process for the preparation thereof The invention relates to compounds of general formula (I), their optically active isomers and salts wherein Ar=alycylic, aromatic or one or more heteroatom containing heterocyclic moiety, optionally substituted by one or more alkoxy-, methylenedioxy-, alk... | 08/21/2001 |
| 6184381 | Process for preparing optically active compounds This document describes a novel and practically excellent process for the preparation of optically active compounds, such as optically active alcohols or amines which are useful for various applications, for example, as synthetic intermediates of pharmace... | 02/06/2001 |
| 6160133 | Synthesis of (S)--methyl-1,3-benzodioxole-5-ethanol and derivatives A process for stereoselectively forming N-substituted dihydro-2,3 benzodiazepines which are useful as AMPA receptor antagonists. The process includes an opening reduction step which sets the stereochemistry of the intermediates and the final compounds to ... | 12/12/2000 |
| 6143907 | 3-phenyl-1-methylenedioxyphenyl-indane-2-carboxylic acid derivatives Invented is an improved process for preparing aromatic ring-fused cyclopentane derivatives. Preferred compounds prepared by this invention are indane carboxylates and cyclopentanopyridine derivatives. The most preferred compounds prepared by this inventio... | 11/07/2000 |
| 6121026 | Enantioselective bioreduction using yeast The invention relates to a class of enantiomerically pure intermediates represented by Formula I, where X is F, Cl, Br, or I, and a novel enantioselective bioreductive process using yeast to form these intermediates, which are useful in the synthesis of e... | 09/19/2000 |
| 6048893 | Substituted phenyl compounds with a substituent having A 1,3-benzodioxole ring This invention is directed to compounds of formula I ##STR1## wherein R1 is CN, CH2 CN, CH.dbd.CHCN, CHO, or CH.dbd.CHCO2 H; R2 is aryl lower alkoxy, heteroaryl lower alkoxy, aryl lower alkylthio or heteroa... | 04/11/2000 |
| 5998408 | Triterpene derivatives with immunosuppressant activity The compounds of Formula I ##STR1## are useful as immunosuppressive agents.... | 12/07/1999 |
| 5952386 | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen... | 09/14/1999 |
| 5814657 | 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular hypotensive agents Compounds of the formula ##STR1## wherein the variables are defined as in the specification, are capable of lowering introaocular pressure in the eye of a mammal.... | 09/29/1998 |
| 5741810 | Cyclopentane heptan(ene)oic acid, 2- heteroarylalkenyl derivatives as therapeutic agents The present invention provides to cyclopentane heptanoic acid, 2 heteroaryl alkyl or alkenyl derivatives which may be substituted in the 1-position with hydroxyl, alkyloxy, amino and amido groups, e.g. 1-OH cyclopentane heptanoic acid, 2 heteroarylalkenyl... | 04/21/1998 |
| 5739166 | Substituted terphenyl compounds for the treatment of inflammation A class of terphenyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II: ##STR1## wherein each of R2 and R3 is independently sel... | 04/14/1998 |
| 5723489 | Aryloxypropanolamine beta 3 adrenergic agonists Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof wherein: R1 to R9 are as defined herein and m is the integer 0 or 1. These compounds are beta 3 adrenergic receptor agonists and are useful, therefo... | 03/03/1998 |
| 5686460 | Carbocyclic diarylmethylene derivatives, processes for their preparation and their uses in therapeutics The present invention relates to the carbocyclic diarylmethylene derivatives of formula (I): ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.... | 11/11/1997 |
| 5686633 | Inks, particularly for ink jet printing Inks, particularly inks for ink jet printing, contain at least one compound of the formula I ##STR1## as a stabilizer. The symbols R1, R2, R3, R4, R3 ' and R4 ' are as defined in claim... | 11/11/1997 |
| 5612381 | 1,2-ethanediol derivative and salt thereof process for producing the same, and cerebral function-improving agent comprising the same This invention relates to a 1,2-ethanediol derivative and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebro... | 03/18/1997 |
| 5599952 | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods Methods of producing carboxylic acid ester derivatives of formulae (I) and (II), which are useful, for instance, as intermediates for producing an anti-hypercholesterolemic agent having an inhibitory effect on HMG-CoA Reductase: ##STR1## wherein... | 02/04/1997 |
| 5559105 | Endothelin receptor antagonists A compound of formula: ##STR1##... | 09/24/1996 |
| 5541204 | Aryloxypropanolamine ଲ 3 adrenergic agonists Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof wherein: R1 to R9 are as defined herein and m is the integer 0 or 1. These compounds are beta 3 adrenergic receptor agonists and are useful, therefo... | 07/30/1996 |
| 5536853 | Opiate receptor ligands Compounds of Formula 1 bind opioid receptors: ##STR1## wherein X and Y are each independently ##STR2##... | 07/16/1996 |
| 5508461 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same An (S)-1-phenyl-2-substituted propane derivative shown by the following formula (I) ##STR1## wherein R1 and R2 represent a lower alkyl group, etc., or R1 and R2 may form together an alkylene group, etc.; R | 04/16/1996 |
| 5472984 | 1,2-ethanediol derivative and salt thereof and cerebral function-improving agent comprising the same This invention relates to a 1,2-ethanediol derivative and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebro... | 12/05/1995 |
| 5420273 | Condensed heterocyclic compounds The invention relates to compounds of the formula ##STR1## wherein R1 is hydrogen, acyl, lower-alkyl or --CHO, --CH2 OR10, --COR7 or OR13 ; R2, R3 and R4 are, ind... | 05/30/1995 |
| 5420301 | Process for the preparation of substituted difluorobenzo-1,3-dioxoles The reaction of 2,2-difluorobenzo-1,3-dioxole with (a) an alkali metal or an alkali metal compound and then (b) a compound R1 -Z1 in which Z1 is a leaving group, or with an aldehyde produces compounds of formula I ##S... | 05/30/1995 |
| 5387593 | Piperazinyl-and piperidinyl-cyclohexanols Novel piperazinyl- and piperidinyl-cyclohexanols of the following formula are useful as anxiolytic agents and have other psychotropic properties ##STR1##... | 02/07/1995 |
| 5369127 | 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular hypotensive agents Compounds of the formula ##STR1## where W is (CH2)n where n is 1 or 2, or n is O and W represents lower alkyl groups attached to each oxygen; m is an integer between 1 and 8; R1 is COOH or a pharmaceutically acceptable sal... | 11/29/1994 |
| 5315018 | Process for the functionalization of organic molecules The present invention relates to the hydroxymethylation of aromatic compounds and the subsequent transformation of the hydroxymethylated aromatic compounds to the polyalkoxyalkylene derivative thereof.... | 05/24/1994 |
| 5276205 | Insecticides Novel insecticides have the formula ##STR1## in which R1 is hydrogen, halogen, C1 -C4 alkyl, C1 -C4 haloalkyl, C1 -C4 alkoxy, C1 -C4 alkylthio, C1... | 01/04/1994 |
| 5270301 | Fluoro-amide derivatives The present invention relates to certain fluoro-amide derivatives, as described herein, which are human leukocyte elastase (HLE) inhibitors making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic a... | 12/14/1993 |
| 5258529 | Process for producing propargylcarbinol compounds The present invention provides a process for producing a propargylcarbinol compound of formula (I): ##STR1## where R1 and R2 are as defined herein. The process comprises reacting a haloallycarbinol compound of formula (II) with ... | 11/02/1993 |
| 5250574 | Aromatic compounds and their compositions for the control of insect pests An aromatic compound of the formula: ##STR1## wherein R1 is, the same or different, a halogen atom, a C1 -C4 alkyl group, a C1 -C4 haloalkyl group, a C1 -C3 alkoxy group or ... | 10/05/1993 |
| 5248834 | Pesticides Pesticidal compounds of formula I I: RA CR3 .dbd.CR4 CHDRB in which formula: RA represents a group ArCR1 R2 - in which Ar represents a phenyl or naphthyl group optionally substituted by on... | 09/28/1993 |
| 5232930 | 2-heteroaryl-substituted benzodioxoic having 5-lipoxygenase inhibitory activity The invention concerns a benzodioxole derivative of the formula I ##STR1## wherein Ar1 is an optionally substituted 9- or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a furth... | 08/03/1993 |
| 5194628 | Process for the preparation of substituted difluorobenzo-1,3-dioxoles The reaction of 2,2-difluorobenzo-1,3-dioxole with (a) an alkali metal or an alkali metal compound and then (b) a compound R1 -Z1 l in which Z1 is a leaving group, or with an aldehyde produces compounds of formula I #... | 03/16/1993 |
