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| Number | Title | Issue Date |
| 8168808 | Fluorinated 1,3-dioxolane compounds, fluorinated polymers of the compounds, and optical or electrical materials comprising the polymers A production method of fluorinated compounds, for producing a compound represented by formula (3) in a fluorine-based solution in a flow of fluorine gas after reaction of at least one type of compounds represented by formula (1) and at least one type of compounds re... | 05/01/2012 |
| 7847110 | Method for producing optionally substituted methylenedioxybenzene The invention relates to a method for producing optionally substituted methylenedioxybenzene. The invention particularly relates to the production of methylenedioxybenzene. The inventive production method is characterized by the fact that it involves the reaction of... | 12/07/2010 |
| 7671221 | Modulators of ATP-Binding Cassette transporters Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The p... | 03/02/2010 |
| 7524976 | Process for preparing difluorobenzo-1,3-dioxole-5-carboxylic acid derivatives The invention relates to a process for preparing difluorobenzo-1,3-dioxole-5-carboxylic acid and derivatives thereof, and to the use thereof for preparing medicaments and crop protection agents. ... | 04/28/2009 |
| 7358248 | Substituted amino carboxylic acids Disclosed are compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of... | 04/15/2008 |
| 7339078 | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to ... | 03/04/2008 |
| 7285518 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions Dibenzo[b]perhydroheterocyclic amine compounds have shown to be particularly useful as stabilizers. The compounds may serve as antioxidants, antiozoants, heat stabilizers and ultraviolet light stabilizers and such compounds are oil soluble, thus particularly suited ... | 10/23/2007 |
| 7282608 | Inhibitors of histone deacetylase The invention provides compoods and methods for treating cell proliferative-diseases. The invention provides new inhibitors of histone deacetylase enzymatic activity, compositions of the compounds comprising the inhibitors and a pharmaceutically acceptable carrier, ... | 10/16/2007 |
| 7276518 | Substituted cyclohexane-1,4-diamine compounds Substituted cyclohexane-1,4-diamine compounds, methods for production thereof, pharmaceutical compositions comprising these compounds and methods of treatment using these compounds. ... | 10/02/2007 |
| 7265130 | NPY Y5 antagonist The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, ... | 09/04/2007 |
| 7236290 | Electrophoretic medium with improved stability An electrophoretic medium comprises a liquid and at least one particle disposed within the liquid and capable of moving therethrough on application of an electric field to the medium. The medium further comprises a free radical scavenger selected from the group cons... | 06/26/2007 |
| 7208169 | Biphenyl carboxamides The invention relates to novel biphenylcarboxamides of the formula (I) in which R1, R2, m, n, R3, Y and A are as defined in the disclosure, to a plurality... | 04/24/2007 |
| 7192982 | Modulators of peroxisome proliferator activated receptors Disclosed is a compound represented by Structural Formula (I): Ar is a substituted or unsubstituted aromatic group. Q is a covalent bond, —CH2— or —CH2CH2—; W is a substituted or unsubstituted alkylene or a substituted or uns... | 03/20/2007 |
| 7161033 | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to ... | 01/09/2007 |
| 7074853 | Photoprotective and lightfastness-enhancing siloxanes Disclosed is a compound of one of the formulae wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 eac... | 07/11/2006 |
| 7060425 | Color photographic material A color photographic material is described containing a compound of formula (I) wherein, if n=1, R1 is, inter alia, a radical of formula (II), and, if n=2, R1 is unsubstituted or C1–C4alkyl- or hydroxy-substituted phenyl... | 06/13/2006 |
| 7045518 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, rela... | 05/16/2006 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 6924276 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors The invention provides dicarboxylic acid-substituted heteroaryl derivatives of the formula G1-(C(R1)R2)n-Q1-B-Q2-(C(R3)R4)m-G2 I or... | 08/02/2005 |
| 6921624 | Optical recording medium Disclosed is an optical recording medium comprising a recording layer. The recording layer contains: a charge generation material generating an electron and a hole by light irradiation; a charge transport material transporting one of the electron and the hole; a cha... | 07/26/2005 |
| 6903086 | Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as IP antagonists This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I: wherein G1 is selected from the group consisting of a, b1 and b2,... | 06/07/2005 |
| 6875884 | Urea derivatives as inhibitors for CCR-3 receptor Urea and thiourea derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful urea and thiourea derivatives can be synt... | 04/05/2005 |
| 6861539 | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to ... | 03/01/2005 |
| 6849653 | Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthri... | 02/01/2005 |
| 6828446 | Aromatic thioether liver X-receptor modulators The present invention is directed to selective LXR modulators, small molecule compounds corresponding to Formula I and is further directed to a process of treating a condition in a mammal that is modulated by LXR using a therapeutically effective dose of a compound ... | 12/07/2004 |
| 6784299 | Substituted aromatic ethers as inhibitors of glycine transport This invention relates to a series of substituted aromatic ethers of the formula I wherein ring A and X and Y are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmaceutic... | 08/31/2004 |
| 6734182 | Aryl sulfonamides and sulfamide derivatives and uses thereof This invention is directed to novel aryl sulfonamide and sulfamide compounds which bind selectively to and inhibit the activity of the human Y5 receptor. This invention is also related to uses of these compounds for the treatment of feeding disorders such as obesity... | 05/11/2004 |
| 6699911 | Catalytic reduction of alkyne compounds A process is provided for the preparation of cyclohexene derivatives of general formula I or II: ##STR1## in which the substituents R1 and R2 independently of one another are defined as follows: R1 is ##STR2## R2... | 03/02/2004 |
| 6683210 | Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, ... | 01/27/2004 |
| 6667307 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particu... | 12/23/2003 |
| 6660728 | Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists ##STR1## The present invention relates to thienyl substituted acylguanidine derivatives, such as compounds of formula (I) in which R1, R2, R4, R6, A, B and D have the meanings indicated in the claims, their phys... | 12/09/2003 |
| 6603024 | Process for the preparation of 3,4-methylenedioxymandelic acid A process for preparing 3,4-methylenedioxymandelic acid by reacting 1,2-methylenedioxybenzene with glyoxylic acid in the presence of a strong acid and of at least one substance selected from the group consisting of an aprotic organic solvent and 100 to 12... | 08/05/2003 |
| 6573397 | Process for producing 3,4-dihydroxybenzonitrile 3,4-dihydroxybenzonitrile useful as a starting compound for synthesis of medicines and agricultural chemicals is produced, with a high yield by chlorinating 3,4-methylenedioxybenzonitrile with sulfuryl chloride or a mixture of molecular chlorine with a ch... | 06/03/2003 |
| 6518315 | Medicinal uses of phenylaikanols and derivatives A compound of formula (I), a pharmaceutically acceptable derivative thereof, wherein Ph is a phenyl radical R1 is H, OH, OC1-4 alkyl, NO2 ; R2 is OH, OC1-4 alkyl, OC.dbd.OC1-4 alkyl or OC.d... | 02/11/2003 |
| 6512140 | Process for the preparation of 1-(mercaptomethyl)-cyclopropaneacetic acid A process for the preparation of highly pure 1-(mercaptomethyl)-cyclopropaneacetic acid is described. Treatment of 1-(hydroxymethyl)-cyclopropaneacetonitrile with an acid provides the corresponding imino ester and/or halo-amide, which when reacted with ... | 01/28/2003 |
| 6472545 | Protein tyrosine phosphatase inhibitors Compounds of formula (I) ##STR1## or therapeutically acceptable salts thereof, are protein tyrosine kinase PTP1B inhibitors. Preparation of the compounds, compositions containing the compounds, and treatment of diseases using the compounds are disclo... | 10/29/2002 |
| 6444615 | Herbicidal imidazolidinetrione and thioxo-imidazolidinediones This invention relates to 1-substituted-phenyl-3-substituted-2-thioxo-4,5-imidazolidinediones and 2,4,5-imidazolidinetriones which have activity as herbicides, to compositions which contain these compounds and to methods of use of these compounds. In... | 09/03/2002 |
| 6436973 | LTA4 hydrolase inhibitors The invention concerns LTA4 hydrolase inhibiting compositions of formula (1) as set forth below. It also concerns their therapeutic, in particular anti-inflammatory, applications. ##STR1##... | 08/20/2002 |
| 6391877 | Aryl sulfonamides and sulfamide derivatives and uses thereof This invention is directed to novel aryl sulfonamide and sulfamide compounds which bind selectively to and inhibit the activity of the human Y5 receptor. This invention is also related to uses of these compounds for the treatment of feeding disorders such... | 05/21/2002 |
| 6380188 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particu... | 04/30/2002 |
