"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 7790909 | Dioxolane derivative and method for producing same Provided are a novel compound which improves the solubility of any one of various lubricating oil additives when used as base oil, in particular, a base oil component in a lubricating oil composition, and is capable of realizing low viscosity/low volatility characte... | 09/07/2010 |
| 7754900 | Method for the production of dioxolane Processes comprising: providing a reactive distillation column having an upper region, a middle region and a lower region; feeding ethylene glycol and an aqueous formaldehyde solution into the reactive distillation column in the middle region of the reactive distill... | 07/13/2010 |
| 7358374 | Purified racemic lasofoxifene and purified lasofoxifene D-tartrate and a method for effective purification of racemic lasofoxifene A method for removing impurities from racemic cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol and purified cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol useful as an estrogen agonist/antagon... | 04/15/2008 |
| 7354893 | Acetals, use thereof as fragrances and methods for production thereof An acetal of formula I: is described in which the radicals R1 to R6 independently of one another are eac hydrogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl or tert-... | 04/08/2008 |
| 7329637 | Methylene dioxy octahydroindene derivatives The present invention is directed to a novel dioxin compound and the use of the novel compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products. ... | 02/12/2008 |
| 7321052 | Process for production of a composition useful as a fuel A process for the preparation of a fuel oil (diesel fuel or heating oil) composition which is a mixture of an alkanol tranesterified fatty acid ester triglyceride and an acetal of glycerol is described. The process preferably provides a prestep of the formation of a... | 01/22/2008 |
| 7252784 | Cyclic ketone peroxide formulations The present invention relates to a cyclic ketone peroxide formulation comprising one or more crystallizing cyclic ketone peroxides, one or more co-crystallizing compounds which solidify in said cyclic ketone peroxide formulation at a temperature above the crystalliz... | 08/07/2007 |
| 7176324 | Hexahydroindan acetal and ketal compounds and their use in perfume compositions The present invention relates to hexahydroindan acetal and ketal compounds and their use as fragrance chemicals suitable for incorporation in fine fragrances, cosmetics, toiletries and related applications. ... | 02/13/2007 |
| 7166622 | Substituted phenylsulfonamide inhibitors of beta amyloid production Compounds of Formula I, wherein R1–R8 are defined herein are provided, together with pharmaceutically acceptable salts, hydrates, metabolites, and/or prodrugs ther... | 01/23/2007 |
| 7122561 | Treatment of skin conditions The present invention provides piperine and analogues or derivatives thereof for the treatment of skin conditions treatable by stimulation of melanocyte proliferation, such as vitiligo, and also for treating skin cancer. The piperine and analogues or derivatives the... | 10/17/2006 |
| 7094418 | Crosslinkable macromers A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The macromer s... | 08/22/2006 |
| 7091344 | Infrared chromophores An infrared dye, characterized in that the dye comprises of Formulae 1 to 5 ... | 08/15/2006 |
| 7074837 | Processes for preparation of bicyclic compounds and intermediates therefor A process for preparing intermediate compound (VII), compound (VIII) and compound (XIV) which will be raw materials for the synthesis of a synthetic antibactrial compound, via compound (I) or compound (X) and then, compound (II), the compounds each being shown below... | 07/11/2006 |
| 7041345 | Chiral compounds III The invention relates to chiral compounds of formula (I) wherein Y1, Y2, Y3, Y4, X1, X2, X3 and X4 have the meaning given in claim 1, to liquid crystalline mixtures comprising at... | 05/09/2006 |
| 6943272 | Norbornane and norbornene derivatives, use thereof and perfumed products containing same The invention concerns a novel compounds of formula (I), wherein the dotted line bond is present or not, and wherein R1 represents: when the dotted line bond is present —CHCH3OH or —CHCH3OCOR or —CHCH3XCH2... | 09/13/2005 |
| 6924276 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors The invention provides dicarboxylic acid-substituted heteroaryl derivatives of the formula G1-(C(R1)R2)n-Q1-B-Q2-(C(R3)R4)m-G2 I or... | 08/02/2005 |
| 6924370 | Crosslinkable macromers A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The macromer s... | 08/02/2005 |
| 6906202 | Purified racemic lasofoxifene and purified lasofoxifene D-tartrate and a method for effective purification of racemic lasofoxifene A method for removing impurities from racemic cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol and purified cis-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol useful as an estrogen agonist/antagon... | 06/14/2005 |
| 6864225 | Cyclic ketals, fragrance compositions containing the same and methods of using the same Compounds of the general formula (I) are described: wherein each of R1, R2, R3, R4, R5 and R6 independently represents a substituent selected from the g... | 03/08/2005 |
| 6844375 | 4-methylene-1,3-dioxolanes as cross-linking agents The invention relates to: 4-methylene-1,3-dioxolanes of the general formula (I) wherein R1 denotes hydrogen, C5-C6-cycloalkyl or C1-C4-alkyl; m and n, which may be the same o... | 01/18/2005 |
| 6830789 | Chiral additives for cholesteric displays A unique class of chiral additive materials is disclosed for use in cholesteric displays that possess a helical twist power substantially independent of temperature. The additives have a solubility and a helical twist power large enough to be used as a single chiral... | 12/14/2004 |
| 6800658 | Substituted diphenyl indanone, indane and indole compounds and analogues thereof useful for the treatment of prevention of diseases characterized by abnormal cell proliferation The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell prolifera... | 10/05/2004 |
| 6777559 | Process for preparing heterocyclic indene analogs A process for the preparation heterocyclic indene analogs, especially with the preparation of 4-hydroxycarbazole or N-protected 4-hydroxycarbazole, involves cyclocarbonylation followed by saponification. This process avoids high temperatures and high catalyst loadin... | 08/17/2004 |
| 6762326 | C2-substituted idan-1-ones and their derivatives, processes for their preparation and their use as pharmaceuticals Embodiments of the invention relate to C2-substituted indan-1-ones and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention include compounds of formula I | 07/13/2004 |
| 6713640 | Process for the recovery of a polyol from an aqueous solution A process for the separation of a polyol or multiple polyols in admixture with other organic compounds, usually those produced with the polyol, is described. The process uses a distillation in a column (11) of a cyclic acetal from an aqueous solution which ac... | 03/30/2004 |
| 6706724 | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use The invention describes novel substituted aryl compounds that are cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions comprising at least one cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that donates, transfer... | 03/16/2004 |
| 6680391 | Treatment of skin conditions The present invention provides piperine and analogues or derivatives thereof for the treatment of skin conditions treatable by stimulation of melanocyte proliferation, such as vitiligo, and also for treating skin cancer. The piperine and analogues or deri... | 01/20/2004 |
| 6677330 | Fluorides of 4-substituted piperidine derivatives The present invention provides a novel compound having an excellent acetylcholinesterase inhibitory effect. That is, it provides a 4-substituted piperidine compound fluoride represented by the following formula, a pharmaceutically acceptable salt thereof ... | 01/13/2004 |
| 6670489 | Process for producing cyclic formal In producing a cyclic formal by feeding an alkylene glycol and a formaldehyde derivative as starting materials to a reaction vessel and reacting them in the presence of a catalyst, the value of amount of alkylene glycol (mole)/amount of formaldehyde deriv... | 12/30/2003 |
| 6610892 | Process for preparing 2,7-dimethyl-2,4,6-octatrienal monoacetals The invention relates to a process for preparing 2,7-dimethyl-2,4,6-octatrienal monoacetals of the general formula I ##STR1## which comprises a) condensing an ester phosphonium salt of the general formula II or an ester phosphonate of the general form... | 08/26/2003 |
| 6521661 | Cyclic peroxides as novel antifungal agents The novel compositions and methods of the subject invention can be used in antifugal applications. The antifugal agents of the subject invention can be used in the treatment of an animal or human having a fugal infection. In a further embodiment the compo... | 02/18/2003 |
| 6515150 | Cyclic acetal compound, polymer, resist composition and patterning process Cyclic acetal compounds of formula (1) wherein k=0 or 1 and n is an integer of 0 to 6 are novel. Using the cyclic acetal compounds as a monomer, polymers are obtained. A resist composition comprising the polymer as a base resin is sensitive to high-energy... | 02/04/2003 |
| 6482851 | Synthesis of dysidiolide and uses thereof This invention provides a process for the preparation of a racemic mixture of dysidiolide a method for inhibiting growth of cancerous cells comprising contracting an amount of the racemic mixture of dysidiolide effective to inhibit the growth of said cell... | 11/19/2002 |
| 6482565 | Photoresist cross-linker and photoresist composition comprising the same The present invention relates to a cross-linker for use in a photoresist which is suitable for a photolithography process using KrF (248 ru), ArF (193 nm), E-beam, ion beam or EUV light source. According to the present invention, preferred cross-linkers c... | 11/19/2002 |
| 6476240 | Monomer and a polymer obtained therefrom This invention relates to a monomer shown by the general formula [1] ##STR1## (wherein X' is a cyclic hydrocarbon residue containing polymerizable double bond(s), which may have a substituent, Z is a spacer or a direct bond and R is a substituted alkyl or... | 11/05/2002 |
| 6420610 | Silver halide photographic light-sensitive material, aromatic aldehyde derivative compound, and image-forming method Aromatic aldehyde compounds of formula (4) and (6) are disclosed, ##STR1## wherein Y is a methylene group with various substitutions and R represents various substituents.... | 07/16/2002 |
| 6395911 | Process for cis-1{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy] ethyl}pyrrolidine This invention provides an improved process for cis-1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy] ethyl}pyrrolidine which is an intermediate for the preparation of (-)cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tet... | 05/28/2002 |
| 6383521 | Wondonin A and process for preparing the same The present invention provides Wondonin A of general formula (I), which is extracted from a two-sponge association of phylum Porifera (sponge) and has antiangiogenic activity, and a process for preparing the same. Wondonin A has no cytotoxicity, but has a... | 05/07/2002 |
| 6376683 | Process for the preparation of (4R,6S)-4-hydroxy-6-hydroxymethyl-tetrahydropyran-2-one The present invention relates to an improved, efficient and enantio-selective process for the synthesis of (4R, 6S)-4-hydroxy-6-hydroxymethyl tetrahydropyran-2-one, employing the Sharpless asymmetric dihydroxylation and regiospecific nucleophilic hyd... | 04/23/2002 |
| 6369099 | Method of locking 1 -OH of vitamin D compounds in axial orientation A method of modifying or altering the structure of a 1-hydroxylated vitamin D compound to increase its biological activity by altering the conformational equilibrium of the A-ring to favor a chair conformation that presents the 1-hydroxyl in... | 04/09/2002 |