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| Number | Title | Issue Date |
| 8097735 | Methods for preparing benzodithiophenes Methods of adding substituents to a benzodithiophene are disclosed. A benzodithiophene is reacted with a reagent to directly add the substituent to the benzene core of the benzodithiophene. This method eliminates steps from prior process and eliminates the need for ... | 01/17/2012 |
| 7956199 | Methods for preparing benzodithiophenes Methods of adding substituents to a benzodithiophene are disclosed. A benzodithiophene is reacted with a reagent to directly add the substituent to the benzene core of the benzodithiophene. This method eliminates steps from prior process and eliminates the need for ... | 06/07/2011 |
| 7928248 | Benzopyran and benzoxepin PI3K inhibitor compounds and methods of use Benzopyran and benzoxepin compounds of Formulas I and II, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms ... | 04/19/2011 |
| 7402607 | DNA-PK inhibitors A compound of formula I: and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R1 and R2 are independently selected from hydrogen, ... | 07/22/2008 |
| 7390613 | Photoactive compounds The present application relates to a compound of formula Ai Xi Bi where Ai and Bi are each individually an organic onium cation; and Xi is anion of the formula −O3S—CF2CF2OCF2CF2—SO3 | 06/24/2008 |
| 7384974 | 4,5-dihydronaphtho[1,2-b]thiophene derivative A 4,5-dihydronaphtho[1,2-b]thiophene derivative expressed by the formula: (wherein R1 is a C1 to C10 1-hydroxyalkyl group or a C1 to C10 acyl group, and R2 a... | 06/10/2008 |
| 7358248 | Substituted amino carboxylic acids Disclosed are compounds and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compounds of... | 04/15/2008 |
| 7332519 | Spirocyclic cyclohexane compounds Spirocyclic cyclohexane compounds, methods for their production, pharmaceutical compositions containing these compounds, and the use of these spirocyclic cyclohexane compounds for treating conditions associated with the nociceptin/ORL1 receptor system, e.g. pain, dr... | 02/19/2008 |
| 7332615 | Hydrophilic analogs of 4,8-dihydrobenzodithiophene-4,8-diones as anticancer agents The present invention discloses hydrophilic derivatives of 4,8-dihydrobenzodithiophene-4,8-diones, which are active as anticancer agents, along with pharmaceutical formulations containing the same. ... | 02/19/2008 |
| 7332492 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor Compounds of formula (I): wherein: X is a group of formula (B): and R1, R2 | 02/19/2008 |
| 7288560 | Spirocyclic cyclohexane derivatives The present invention relates to spirocyclic cyclohexane compounds, to methods for their production, to pharmaceutical compositions containing these compounds, to methods of treatment using such compounds and to the use of such spirocyclic cyclohexarie compounds for... | 10/30/2007 |
| 7253292 | Synthesis of cyclopentadiene derivatives A process for preparing cyclopentadiene derivatives comprising the steps of: a) coupling a five membered heterocycle ring with a five or six membered heterocycle ring; b) reacting the obtained compound with a carbonilating system: c) reducing the obtained compound. | 08/07/2007 |
| 7244516 | Organic electroluminescence device An organic electroluminescence device including an organic layer having a light emission region and being disposed between an anode and a cathode is provided. The organic layer contains, as an organic light-emitting material, a compound represented by the following ... | 07/17/2007 |
| 7241903 | Metallocenes, use in catalyst system for producing olefin polymers A metallocene compound of formula (I): wherein M is zirconium, titanium and hafnium; X is a hydrogen atom, a halogen atom or a hydrocarbon radical; R1 is a linear C1-C20-alkyl radical; R2 is a hydrogen atom or hydrocarbon ... | 07/10/2007 |
| 7175961 | Photopatternable molecular circuitry Bistable molecules are provided with at least one photosensitive functional group. As thus constituted, the bistable molecules are photopatternable, thereby allowing fabrication of micrometer-scale and nanometer-scale circuits in discrete areas without relying on a ... | 02/13/2007 |
| 7144885 | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders This invention relates to a novel fused tricyclic heterocycle of the formula (Ia, Ib) and its use for the treatment of hyper-proliferative disorders ... | 12/05/2006 |
| 7144683 | Photopatternable molecular circuitry Bistable molecules are provided with at least one photosensitive functional group. As thus constituted, the bistable molecules are photopatternable, thereby allowing fabrication of micrometer-scale and nanometer-scale circuits in discrete areas without relying on a ... | 12/05/2006 |
| 7135579 | Dibenzothiophene oxide compound, and process for producing the same There are disclosed novel compounds, liquid crystal compositions, polymers, optically anisotropic producgs, and optical or liquid crystal elements that have large refractive index anisotropy, mix easily with other liquid crystals, have advantageous stability against... | 11/14/2006 |
| 7101905 | Pharmaceutically active compounds and methods of use New fused thiophene compounds are provided and methods of using those compounds for a variety of therapeutic indications. Compounds of the invention are particularly useful for treatment of neuropathic pain. ... | 09/05/2006 |
| 7101998 | Fused ring compounds, and their use as cationic photoinitiators Compounds of formula (I): [in which: R1 represents a direct bond, an oxygen atom, a group >CH2, a sulphur atom, a group >C═O, a group —(CH2)2— or a group of formu... | 09/05/2006 |
| 6967216 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor Compounds of formula (I): wherein: X is a group of formula (A) or (B): and R1, R2, R3, R4, ... | 11/22/2005 |
| 6943275 | Process of preparing a disubstituted 9-alkylidenefluorene or a derivative thereof The invention relates to a process of preparing disubstituted 9-alkylidenefluorenes and structure analogous compounds, to novel compounds and intermediates prepared by this process, their use for the preparation of conjugated polymers and copolymers thereof, and to ... | 09/13/2005 |
| 6930190 | Process for the preparation of heterocyclic pentalene derivatives A process for preparing heterocyclic pentalene derivative having formula (I): wherein w is a sulfur atom (S), an oxygen atom (O) or a NR or PR group, wherein R is an hydrocarbon group; R1, R2, R3, and R4, equal to or diffe... | 08/16/2005 |
| 6916938 | Method for preparing sulfone or sulfoxide compound There is provided a method for preparing a sulfone or sulfoxide compound, characterized in that a sulfide compound is allowed to react with hydrogen peroxide in the presence of a metal oxide catalyst formed by the reaction of hydrogen peroxide with at least one meta... | 07/12/2005 |
| 6913710 | Reactive mesogenic benzodithiophenes The invention relates to new reactive mesogenic benzodithiophene derivatives, their use as semiconductors or charge transport materials, in optical, electro-optical or electronic devices like for example liquid crystal displays, optical films, organic field effect t... | 07/05/2005 |
| 6894177 | Intermediate compounds of non-nucleoside reverse transcriptase inhibitors Compounds of the formula I: where; R1 is O, S; R2 is an optionally substituted nitrogen-containing heterocycle, wherein the nitrogen is located at the 2 position relative... | 05/17/2005 |
| 6849202 | COMPOUND HAVING PHENYLACETYLENE STRUCTURE, LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC PRODUCT, OPTICAL OR LIQUID CRYSTAL ELEMENT, DIBENZOTHIOPHENE COMPOUND, INTERMEDIATE, AND PROCESS FOR PRODUCING THE SAME There are disclosed novel compounds, liquid crystal compositions, polymers, optically anisotropic products, and optical or liquid crystal elements that have large refractive index anisotropy, mix easily with other liquid crystals, have advantageous stability against... | 02/01/2005 |
| 6825357 | Benzodioxinothiophenes, their preparation and use The invention relates to substituted or unsubstituted benzodioxinothiophenes, their preparation and their use for preparing electrically conductive oligomers or polymers, also oligomers or polymers comprising these thiophene derivatives as repeating unit. ... | 11/30/2004 |
| 6818260 | Thienothiophene derivatives The invention relates to new thienothiophene derivatives, their use as semiconductors or charge transport materials, in optical, electrooptical or electronic devices like for example organic field effect transistors (FET or OFET) for thin film transistor liquid crys... | 11/16/2004 |
| 6800656 | Tricyclic compounds and method of treating herpes virus The present invention provides a compound of the formula and pharmaceutically acceptable salts having useful antiviral activity against viruses of the herpes family. Wherein: X=O, (CH2)m, S, ... | 10/05/2004 |
| 6693136 | Fluorenes and anthracenes that inhibit P2X3 and P2X2/3 containing receptors Compounds of formula (I) ##STR1## are novel P2X3 and P2X2 /P2X3 containing receptor antagonists and are useful in treating pain, urinary incontinence, and bladder overactivity.... | 02/17/2004 |
| 6645401 | Conjugated copolymers of dithienothiophene with vinylene or acetylene Conjugated copolymers of dithienothiophene with vinylene or acetylene are suitable for use as semiconductors or charge transport materials in optical, electrooptical or electronic devices including field effect transistors, electroluminescent, photovoltai... | 11/11/2003 |
| 6620835 | Method of inhibiting matrix metalloproteinases The present invention relates to a method of inhibiting matrix metalloproteinases using compounds that are dibenzofuran sulfonamide derivatives having the Formula I ##STR1## More particularly, the present invention relates to a method of treating dis... | 09/16/2003 |
| 6602903 | Substituted heterocyclic compounds The invention relates to compounds of formula (I): ##STR1## and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.... | 08/05/2003 |
| 6555697 | Method of preparing a benzofuran or benzothiophene compound The invention concerns a novel method for preparing a benzofuran or benzothiophene compound by cyclizing an aromatic compound bearing a side-chain comprising at least two carbon atoms, one of the carbon atoms being bound to the benzene cycle by an oxygen ... | 04/29/2003 |
| 6514967 | Compound for preparing medicines for treating pathologies involving extracellular glutamate, and methods for obtaining same The invention relates to compounds of the following general formula (I): ##STR1## in which: R1 and R2 represent a hydrogen atom, or form a ring, especially a benzene ring, R3 represents a hydrogen atom or an alkyl group, e... | 02/04/2003 |
| 6515144 | Oligothiophenes and synthesis thereof Novel oligothiophenes and intermediates therefor are disclosed together with a process for synthesizing them. The oligothiophenes are in the form of a helix which contains five-membered rings unsaturated heterocycles that are cross-conjugated and annelate... | 02/04/2003 |
| 6455684 | Insitu assay of substance in biological sample using labeled probe A method for analyzing an objective substance, comprising reacting a labeled probe with an objective substance on a biological sample, said probe comprising a label substance of the formula (I): ##STR1## wherein A1 is an aromatic group, R1... | 09/24/2002 |
| 6429312 | N-aminoalkyldibenzothiopencarboxamide receptor subtype specific ligands Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: R1, R2, R3, R4 are the same or different and represent hydrogen, C1 -C6 ... | 08/06/2002 |
| 6423870 | Tricyclic compounds, preparation method and pharmaceutical compositions containing same The invention concerns compounds of formula (I) in which: A forms a tricyclic system of formula A1, A2, A3 or A4 ; R1 represents a hydrogen atom, an alkyl, hydroxy, alkoxy or oxo group; (R2... | 07/23/2002 |
