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Penn Jillette of Penn and Teller fame has patented a "Hydro-Therapeutic Stimulator", which uses a hot tub for stimulation.
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| Number | Title | Issue Date |
| 8168807 | Process for one-stage preparation of 2-methyltetrahydrofuran from furfural over two catalysts in a structured bed The present invention provides a process for preparing 2-methyltetrahydrofuran by one-stage hydrogenation of furfural with a hydrogen-comprising gas in the presence of a structured bed of at least one copper catalyst and at least one catalyst which comprises at leas... | 05/01/2012 |
| 8129548 | Process for the purification of 1,4-butanediol A process for the purification of a crude liquid feed stream comprising 1,4-butanediol and a minor amount of 2-(4-hydroxybutoxy)-tetrahydrofuran and/or precursors thereof wherein the process comprises passing the crude feed in the presence of hydrogen in a reaction ... | 03/06/2012 |
| 7468446 | Substituted heterocyclic compounds and uses thereof The present invention relates to substituted heterocyclic compounds and compositions comprising a substituted heterocyclic compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering to a subject... | 12/23/2008 |
| 7442810 | Method for the production of defined mixtures of THF, BDO and GBL by gas phase hydrogenation A process for variably preparing mixtures of optionally alkyl-substituted BDO, GBL and THF by two-stage hydrogenation in the gas phase of C4 dicarboxylic acids and/or derivatives thereof, which comprises a) hydrogenating... | 10/28/2008 |
| 7432284 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 10/07/2008 |
| 7429669 | Therapeutic compounds Disclosed herein are compounds of the formula or salts or bioisosteres thereof. Therapeutic methods, medicaments, and compositions related thereto are also disclosed. ... | 09/30/2008 |
| 7423061 | Substitute thiophenes and uses thereof This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cancer. ... | 09/09/2008 |
| 7419943 | Methanoazuenofurans and methanoazulenone compounds and uses of these compounds as fragrance materials The use of novel methanoazulenofuran and methanoazulenone compounds for use as fragrance chemicals, suitable for use incorporated in a wide variety of products such as perfumes, colognes and personal care products having a structure ... | 09/02/2008 |
| 7417068 | EPreceptor antagonists A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein one of R2 and R5 is: (i) H or an optionally substituted C1-4 a... | 08/26/2008 |
| 7371777 | Cyclic compound and PPAR agonist The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. ... | 05/13/2008 |
| 7351311 | Method for purifying tetrahydrofuran by distillation Crude water-containing tetrahydrofuran is purified by passing the crude tetrahydrofuran through three distillation columns, withdrawing water from the bottom of the first column, recycling water-containing tetrahydrofuran from the top of the second column into the f... | 04/01/2008 |
| 7351734 | Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors The present invention relates to aminoindane derivatives having the formula I wherein X, Y, U, R1-2, R13-16 and R are as defined in the claims, or an acid addition salt thereof. The compounds of the invention posses the combined effect of serot... | 04/01/2008 |
| 7345181 | Process for preparing prostaglandin derivatives and starting materials for the same The present invention provides a process for preparing benzoprostacycline derivatives of formula (1), i.e. 5,6,7-trinor-4,8-inter-m-phenylene PGI2 derivatives, and vinyl tin compounds of formula (III) as starting materials for the same. ... | 03/18/2008 |
| 7329634 | 3-Phenyl substituted 3-substituted-4ketolactams and ketolactones The invention relates to novel 3-phenyl-substituted, 3-substituted 4-ketolactams and -lactones of the formula (I) in which Q, W, X, Y, A, B and G are as defined in the disclosure, to proc... | 02/12/2008 |
| 7316851 | Electroluminescent material, electroluminescent element and color conversion filter An electroluminescent element is disclosed, comprising an electroluminescent material and a fluorescent substance emitting light having an emission maximum at the wavelength different from that of light emitted from the electroluminescent material upon absorption of... | 01/08/2008 |
| 7276573 | Method for producing monoesters and diesters of polytetrahydrofuran and of tetrahydrofuran copolymers The present invention provides a process for preparing mono- or diesters of polytetrahydrofuran or of tetrahydrofuran copolymers by polymerizing tetrahydrofuran in the presence of at least one telogen and/or of a comonomer over an acidic catalyst, wherein the polyme... | 10/02/2007 |
| RE39794 | Process for the simultaneous production of maleic anhydride and its hydrogenated derivatives A process is described for the co-production of maleic anhydride and at least one C4 compound selected from butane-1,4-diol, γ-butyrolactone, and tetrahydrofuran in which maleic anhydride is produced by partial oxidation of a hydrocarbon feedstock select... | 08/21/2007 |
| 7256203 | Dicationic 2,5-diarylfuran aza-analogs as anti-protozoan agents A compound of Formula (I): wherein: X is selected from the group consisting of O, S, and NR17, where R17 is hydrogen or lower alkyl; A and... | 08/14/2007 |
| 7148241 | Dicationic 2,5-diarylfuran aza-analogs as anti-protozoan agents A compound of Formula (I): wherein: X is selected from the group consisting of O, S, and NR17, where R17 is hydrogen or lower alkyl; C | 12/12/2006 |
| 7148318 | Method for producing polytetrahydrofurane having a low color indices The invention provides a process for preparing polytetrahydrofuran, tetrahydrofuran copolymers, their monoesters or diesters and the monoesters or diesters of polytetrahydrofuran having a low color number in the presence of a catalyst, which comprises converting cru... | 12/12/2006 |
| 7144909 | Phenoxy substituted benzocondensed heteroaryl derivatives as thyroid receptor ligands This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subcllinical hyperthyrodis... | 12/05/2006 |
| 7122561 | Treatment of skin conditions The present invention provides piperine and analogues or derivatives thereof for the treatment of skin conditions treatable by stimulation of melanocyte proliferation, such as vitiligo, and also for treating skin cancer. The piperine and analogues or derivatives the... | 10/17/2006 |
| 7109343 | Metal catalysts and methods for making and using same Compounds having the formula: are disclosed. M1 and M2 are the same or different and are transition metal atoms or ions; Z2 and Z3, independently, are the atoms necessa... | 09/19/2006 |
| 7105707 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds Mono- and disubstituted aryl or heterocyclic acetylenes are produced by a process comprising reacting an aryl nitrile with an alkynylzinc compound, a bis-alkynylzinc compound, or an alkynylmagnesium compound, in the presence of a nickel/phosphine catalyst. ... | 09/12/2006 |
| 7091344 | Infrared chromophores An infrared dye, characterized in that the dye comprises of Formulae 1 to 5 ... | 08/15/2006 |
| 7081467 | C2-disubstituted indan-1-ones and their derivatives, processes for their preparation and their use as pharmaceuticals The present invention is directed C2-disubstituted indan-1-ones of the Formula I, physiologically acceptable salts, and physiologically functional derivatives thereof, and pharmaceutical compositions comprising s... | 07/25/2006 |
| 7074944 | Method for producing polytetrahydrofuran In a process for the single-stage preparation of polytetrahydrofuran and/or tetrahydrofuran copolymers having a mean molecular weight of from 650 to 5000 dalton by polymerization of tetrahydrofuran over an acid catalyst in the presence of at least one telogen and/or... | 07/11/2006 |
| 7064222 | Processes for the preparation of 2-methylfuran and 2-methyltetrahydrofuran Processes are disclosed for the preparation of 2-methylfuran and 2-methyltetrahydrofuran. The continuous vapor-phase processes are commercially viable and efficient because they permit the preparation of 2-methylfuran and 2-methyltetrahydrofuran using commercially-a... | 06/20/2006 |
| 7057055 | Process for preparing a deuterated or tritiated compound A process for labeling organic compounds with deuterium and tritium is described using specific catalysts. ... | 06/06/2006 |
| 7049329 | Amines that inhibit a mammalian anandamide transporter, and methods of use thereof One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds of the present invention will also find use in the treatment of numero... | 05/23/2006 |
| 7045642 | Process for preparing a deuterated or tritiated compound A process for labeling organic compounds with deuterium and tritium is described using specific catalysts. ... | 05/16/2006 |
| 6949583 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same The invention relates to benzofuran or benzothiophene derivatives, to processes for preparing them, to pharmaceutical compositions comprising them, and to the method of use thereof in the treatment of pathological syndromes of the cardiovascular system. ... | 09/27/2005 |
| 6936629 | Compounds and methods for the treatment or prevention of flavivirus infections The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection. ... | 08/30/2005 |
| 6930188 | Stable hydrate of a muscarinic receptor antagonist A stable solid hydrate of a muscarinic receptor antagonist is useful in the treatment of irritable bowel syndrome, diverticular disease, oesophageal achalasia, chronic obstructive airways disease, over active bladder (including symptoms of incontinence, urge and fre... | 08/16/2005 |
| 6921831 | Modified BiMo catalyst and process for use thereof Modified lead/bismuth/molybdate catalysts containing vanadium, copper, or gold have been prepared, and are selective to the corresponding furan compound from the gas phase oxidation of an unsaturated acyclic hydrocarbon such as butadiene. ... | 07/26/2005 |
| 6906196 | Processes for the preparation of 1,5-diaryl-3-substituted-pyrazoles Provided are processes and chemical intermediates useful for preparing a compound of the formula I wherein X is selected from the group consisting of C1-C6 | 06/14/2005 |
| 6903132 | Non-peptide GnRH agents, pharmaceutical compositions and methods for their use Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and ster... | 06/07/2005 |
| 6900196 | Serine protease inhibitors Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardi... | 05/31/2005 |
| 6900160 | Triazolo-epothilones The invention relates to triazolo-thiazole analogues of epothilone A and epothilone B. ... | 05/31/2005 |
| 6894039 | Selenophene anti-tumor agents Novel selenophene compounds useful as anti-tumor agents are described. Preferred compounds include compounds of formula I: wherein R1 and R2 are independently selected fro... | 05/17/2005 |
