...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 7705164 | Metalloprotein inhibitors The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and... | 04/27/2010 |
| 7550607 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses Processes for preparing racemic and optically pure 3,6-dihydro-2H-pyrans of formulae H, I, N and O are described. These compounds may be further transformed into compounds of formulae J, K, L, M, P, Q, S, T, U, V, Y and Z with potential pharmaceutical, pharmaceutica... | 06/23/2009 |
| 7361388 | Liquid-crystalline compounds having a tetrahydropyran ring The invention relates to liquid-crystalline compounds of formula (I), wherein R11, X11, Z11, Z12, Z13, L11, L12, L13, L14, L15 and L16 have the m... | 04/22/2008 |
| 7304169 | Process for producing tetrahydropyran-4-ol, intermediate therefor, and process for producing the same The present invention relates to a process for preparing tetrahydropyran-4-ol which comprises the steps of (A) a cyclization step of preparing tetrahydropyranyl-4-formate represented by the formula (1): by reacti... | 12/04/2007 |
| 7258902 | Chiral 3,4-dihydro-2H-pyran compounds The invention relates to chiral 3,4-dihydro-2H-pyran compounds and diastereomers thereof, and to the use of these compounds as chiral dopants for liquid-crystalline systems. The invention furthermore relates to non-polymerizable or polymerizable liquid-crysta... | 08/21/2007 |
| 7244750 | Active substance combinations having insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain active compounds that together have unexpectedly good insecticidal and acaricidal properties. ... | 07/17/2007 |
| 7232845 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 06/19/2007 |
| 7205289 | Combinations of active ingredients with insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 04/17/2007 |
| 7205333 | Multivalent neuraminidase inhibitor conjugates The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which ... | 04/17/2007 |
| 7148240 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same The invention relates to benzofuran or benzothiophene derivatives of general formula: These compounds are of use as medicinal products, in particular in the treatment of pathological syndromes of the cardiovascular... | 12/12/2006 |
| 7148363 | Process for preparing acrylate compound An acrylate compound of formula (4): is produced by allowing an acrylic acid compound of formula (1): to react with an unsaturated compound of formula (2) or... | 12/12/2006 |
| 7102027 | Adamantanetricarboxylic acid derivatives An adamantanetricarboxylic acid derivative is represented by following Formula (1): wherein X is a hydrogen atom or a hydrocarbon group; and R1, R2 and R3 may be the same as or di... | 09/05/2006 |
| 7098225 | Active compound combinations having insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain active compounds that together have unexpectedly good insecticidal and acaricidal properties. ... | 08/29/2006 |
| 7091233 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 08/15/2006 |
| 7078540 | Substituted aromatic-ring compounds, process for producing the same, and use A compound of the formula: wherein R1 is an aliphatic hydrocarbon group optionally having substituent(s), an aromatic hydrocarbon group optionally having substituent(s), a heterocyclic group optionally... | 07/18/2006 |
| 6919090 | Active substance combinations with insecticidal and acaricidal properties The invention relates to novel active combinations of certain cyclic ketoenols and certain active compounds that together have unexpectedly good insecticidal and acaricidal properties. ... | 07/19/2005 |
| 6852866 | Triazole linked carbohydrates Disclosed is an invention concerning triazolyloligosaccharides, oligosaccharides wherein the bonding between the saccharide groups is via a triazole group and methods for their preparation. ... | 02/08/2005 |
| 6833462 | Process for preparing acrylate compound An acrylate compound of formula (4): is produced by allowing an acrylic acid compound of formula (1): to react with an unsaturated compound of formula (2) or (3): | 12/21/2004 |
| 6686481 | Highly purified simvastatin compositions The present invention relates to a process to prepare semi synthetic statins, to intermediates formed during said process and to highly purified simvastatin produced by the process.... | 02/03/2004 |
| 6489343 | Tetrahydropyran derivatives and their use as therapeutic agents The present invention relates to compounds of the formula (I): ##STR1## wherein R1 is fluorine or trifluoromethyl; R2 is fluorine or trifluoromethyl; R3 is methyl or hydroxymethyl; R4 represents a variety of substituents;... | 12/03/2002 |
| 6451766 | Neuraminic acid derivatives, their preparation and their medical use Compounds of formula (I) or their salts or esters: ##STR1## [wherein R1 is alkyl or haloalkyl; R2 and R3 each represents hydrogen or aliphatic acyl; X is hydroxy, halogen, alkoxy, or a group of formula Ra O--, w... | 09/17/2002 |
| 6436930 | Thio derivatives of sordarin as antifungal agents The present invention relates to antifungal compounds having the structural formula: ##STR1## and pharmaceutically acceptable salts, solvates and prodrugs thereof. The present invention further relates to pharmaceutical compositions containing said c... | 08/20/2002 |
| 6392061 | Process for making (2S, 3S, 5S) oxetanone derivatives This invention relates to novel processes for making (2S, 3S, 5S) oxetanone derivative lipase inhibitor compounds and intermediates therefor, which processes for producing such derivatives that are useful as lipase inhibitors are capable of being scaled t... | 05/21/2002 |
| 6271425 | Process for producing alcohols A novel process for producing alcohols, characterized by reacting an organic halide represented by the formula R--X (wherein R means an organic residue and X means a halogen atom) with oxygen molecules in the presence of an organotin compound and a reduci... | 08/07/2001 |
| 6147231 | Process for producing 2(2-hydroxymethylphenyl)acetamide derivative and intermediate for the production thereof A process for producing a compound of the formula (I): ##STR1## wherein R1 and R2 are the same or different and are hydrogen or alkyl, and R is hydrogen or alkyl, which comprises removing the protective group (P) of hydroxyl of ... | 11/14/2000 |
| 6136986 | Process for preparing substituted chroman derivatives The invention relates to a process for preparing substituted chroman derivatives of the general formula VII, ##STR1## where X is the group --CN, --COOR3, --CHO, --CH2 OR7 or --CH(OR8)2, R2 | 10/24/2000 |
| 6136853 | Sordarin derivatives PURPOSE: To produce a novel antibiotic substance zofimarin having antimicrobial activity against fungi and obtain an antimicrobial agent containing the antibiotic substance zofimarin as an active constituent, by cultivating a microorganism, belonging to t... | 10/24/2000 |
| 6057342 | Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof The present application describes amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein one of D and D' may be C(.dbd.NH)NH2 a... | 05/02/2000 |
| 6051723 | 3-aryl-tetronic acid derivatives The present invention relates to new 3-aryl-4-hydroxy-Ɗ3 -dihydrofuranone derivatives of the formula (I) ##STR1## in which A and B together with the carbon atom to which they are bonded form an unsubstituted or substituted 5- to 7-membere... | 04/18/2000 |
| 6040463 | Sordarin derivatives Sordarin derivatives are antifungal agents useful in the treatment and/or prevention of human and animal fungal infections, as well as in the control of phytopathogenic fungi in crops.... | 03/21/2000 |
| 6030996 | Mur D inhibiting compounds, compositions containing such compounds and methods of use The present invention addresses compounds which inhibit Mur D. The compounds are represented by structural formula 1: ##STR1## wherein: X represents OH, OC1-6 alkyl, O-aryl, O-Har, uridinyl, 5-iodouridinyl or O--Y+, wherein Y | 02/29/2000 |
| 6025519 | Process for preparing cyclobutane-1,2-dicarboxylic esters Cyclobutane-1,2-dicarboxylic esters of the formula: ##STR1## in which R1 is a C1-8 -alkyl group, an optionally substituted mono- or bicyclic cycloaliphatic group having 3 to 10 ring carbon atoms, an optionally substituted aryl o... | 02/15/2000 |
| 6001823 | Treatment or prophylaxis of diseases caused by pilus-forming bacteria Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infect... | 12/14/1999 |
| 5990156 | 6-Carboxamido dihydropyran derivatives Compounds of formula (I), ##STR1## wherein R1 represents OR5, SR5, NR5 R6, N(OR5)R6 or N(NR5 R6)R6 ; X represents OH, N3, NR... | 11/23/1999 |
| 5972996 | 4-cyano-4-deformylsordarin derivatives 4-Cyano-4-deformylsordarin derivatives are antifungal agents useful in the treatment and/or prevention of human and animal fungal infections, as well as in the control of phytopathogenic fungi in crops.... | 10/26/1999 |
| 5935995 | Prodrugs for the therapy of tumors and inflammatory disorders Compounds of the formula I glycosyl-Y--C(.dbd.Y)--X--!p --W(R)n --Z--C(.dbd.Y)-active compound (I) are described which are suitable for the treatment of carcinomatous diseases, autoimmune... | 08/10/1999 |
| 5869523 | Process for the preparation of 6-(substitutedaminopropionyl)-derivatives of forskolin Process for the preparation of 6-(substitutedaminopropionyl)-derivatives of forskolin Process for the manufacture of 6ଲ-(3-substitutedamino) propionyloxy forskolin derivatives of the general formula ##STR1##... | 02/09/1999 |
| 5820783 | Chiral compounds Chiral compounds of the formula I ##STR1## where R1 is hydrogen or --Y--Z--Y1, R2 is ##STR2## and X is hydrogen, fluorine, chlorine, bromine, iodine, hydroxyl or OR1, where Y is a direct bond, CO or C | 10/13/1998 |
| 5811028 | Optically active dihydropyran derivative, and liquid crystal composition, liquid crystal device, and racemic mixture comprising the derivative A 2H-5,6-optically active dihydropyran derivative represented by the general formula (I) or (I'): ##STR1## wherein Rf represents a fluoroalkyl group having 1 or 2 carbon atoms; a liquid crystal composition and a liquid crystal device comprising the ... | 09/22/1998 |
| 5808111 | Stable acitretinoid compounds Novel acitretinamide compounds which are soluble and stable in water and useful in aqueous delivery systems, particularly to treat cancer, are provided. The novel acitretinamide compounds, 1-(D-glucopyranosyl)acitretinamide, 1-(D-glucopyranuronosyl)acitre... | 09/15/1998 |