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| Number | Title | Issue Date |
| 7825267 | Synthesis of FR901464 and analogs with antitumor activity The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with d... | 11/02/2010 |
| 7390803 | Tetrahydropyranyl cyclopentyl benzylamide modulators of chemokine receptor activity The present invention is directed to compounds of the formula (I) (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R27, R28... | 06/24/2008 |
| 7344761 | Liquid-crystalline compounds The invention relates to liquid-crystalline compounds of the formula (I), where R11, X11, L11, Y and W are as defined in claim 1, and to the use thereof in liquid-crystalline media, to liquid-crystalline media comprising at least one... | 03/18/2008 |
| 7312230 | Carboxylic acid derivatives as IP antagonists This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I: wherein: R1, R2, and R3 ... | 12/25/2007 |
| 7282598 | Synthetic methods for preparing procyanidin oligomers Processes are disclosed for the production of linear and branched procyanidin oligomers having “n” procyanidin monomeric units where n is 2 to 18. The processes include coupling protected, activated monomers with an unprotected monomer to produce a partially pro... | 10/16/2007 |
| 7268240 | Synthetic methods for polyphenols A process is disclosed for the production of polyphenol oligomers having n polyphenol monomeric units, n being an integer from 2-18. The process includes coupling of a protected polyphenol, having protected phenolic hydroxyl groups, with a C-4 functionalized polyphe... | 09/11/2007 |
| 7244855 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins Various processes are disclosed for preparing procyanidin oligomers having (4,8)-interflavan linkages. In an improved process, a tetra-O-protected-epicatechin or -catechin monomer or oligomer is coupled with a protected, C-4 alkoxy-activated-epicatechin or -catechin... | 07/17/2007 |
| 7235351 | Squalirium compound, thermally developable photographic material containing said compound, and image forming method thereof A thermally developable photographic material containing a support, provided thereon: (i) a photosensitive layer containing photosensitive silver halide particles, and (ii) a layer containing at least one represented by formula below on one or both surfaces of the s... | 06/26/2007 |
| 7217465 | Pyran derivative A light-emitting compound that can be easily applied to vacuum vapor deposition and exhibit long wavelength light is disclosed. Further, a light-emitting element without inferior luminescence properties due to the carbonization of a light-emitting compound during va... | 05/15/2007 |
| 7157489 | HIV protease inhibitors Compounds useful for inhibiting HIV protease are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating wild-type HIV and of multidrug-resistant strains of HIV, also are disclosed. ... | 01/02/2007 |
| 7145015 | Benzocycloheptenes, process for their production, pharmaceutical preparations that contain that latter as well as their use for the production of pharmaceutical agents Benzocycloheptenes of formula (I), in which R1, R2 and Y have the meanings that indicated herein, exhibit selective estrogenic activity on bones and are suitable for the production of pharmaceutical agents, especially for prophylaxis and therap... | 12/05/2006 |
| 7132001 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers The object of the present patent application are 3-aminophenol derivatives of formula (I) or the physiologically compatible, water-soluble salts thereof and colorants based on a developer-coupler combination cont... | 11/07/2006 |
| 7128764 | M-aminophenol derivatives and coloring agents containing them The object of the present patent application are 3-aminophenol derivatives of formula (I) or the physiologically tolerated, water-soluble salts thereof wherein R denotes a heterocyclic aromatic 5-membered ring of... | 10/31/2006 |
| 7122574 | Treatment of hypertension Polyphenol-containing compositions, for example procyanidins and derivatives thereof, and their use for treating hypertension are disclosed. Compositions may be used for human and veterinary use, and may be, for example, in a form of a food, a dietary supplement or ... | 10/17/2006 |
| 7122061 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives The present invention has for an object compounds of formula (I) and colorants containing these 4-aminobiphenyl-3-ol derivatives of general formula (I) for dyeing keratin fibers, particularly hair, wherein | 10/17/2006 |
| 7094801 | Chalcone derivatives and their use to treat diseases The invention relates to compounds, pharmaceutical compositions and methods of using compounds of the general formula or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the ... | 08/22/2006 |
| 7094803 | Biologically active raspailamide compounds The subject invention provides novel compositions of biologically active polyketide compounds that can advantageously be used in blocking cellular proliferation and treatment of cancer. ... | 08/22/2006 |
| 6998417 | Compositions for, and methods of, treating atherosclerosis Disclosed and claimed are cocoa extracts, compounds, combinations thereof and compositions containing the same, such as polyphenols or procyanidins, methods for preparing such extracts, compounds and compositions, as well as uses for them, especially a polymeric com... | 02/14/2006 |
| 6840965 | P-aminophenols and colorants containing said compounds The object of the invention are p-aminophenol derivatives of general formula (I) or physiologically tolerated, water-soluble salts thereof and oxidative coloring preparations based on a developer-coupler combination co... | 01/11/2005 |
| 6720432 | Synthesis of epecatechin-4α, 8-epicatechin dimers and derivatives thereof Oligomeric procyanidins containing 4α-linked epicatechin units are rare in nature and have hitherto not been accessible through stereoselective synthesis. Provided herein is the preparation of the prototypical dimer, epicatechin-4α,8-epicatechin, by reaction of th... | 04/13/2004 |
| 6720353 | Plant proanthocyanidin extract effective at inhibiting adherence of bacteria with p-type fimbriae to surfaces The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type Escherichia coli. These extracts can be ob... | 04/13/2004 |
| 6608102 | Plant proanthocyanidin extract effective at inhibiting adherence of bacteria with P-type fimbriae to surfaces The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type Escherichia coli. These extracts can b... | 08/19/2003 |
| 6506507 | Methine compound, material for organic luminescence element, and organic luminescence element using the same A novel methine compound which is represented by the following formula (I): ##STR1## wherein R1, R2, R3, R4 and R5 each represents a hydrogen atom or a substituent; X represents an oxygen atom, a sulfur ... | 01/14/2003 |
| 6403777 | Metalloligands for cleaving nucleic acids Transition metal complexes, referred to hereinafter as "metalloligands", that catalyze the degradation of DNA and the cleavage of RNA at select sites are provided. In one embodiment, the metalloligand has the following structure: ##STR1## wherein R1 ... | 06/11/2002 |
| 6294557 | Pyrrolidinyl and pyrrolinyl ethylamine compounds as kappa agonists A compound of the following formula: ##STR1## and the salts thereof, wherein A is hydrogen, halo, hydroxy, or the like; the broken line represents an optional double bond with proviso that if the broken line is a double bond, then A is absent; Ar1 | 09/25/2001 |
| 6245804 | Nonsteroidal gestagens This invention describes the new, nonsteroidal gestagens of general formula I ##STR1## in which A, B, Ar, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very ... | 06/12/2001 |
| 6235775 | Acetone adduct of fungicidal V-28-3M The present invention provides an acetone adduct of V-28-3M to be used as an intermediate for producing V-28-3M which is useful as a fungicide, a process for producing it and a process for purifying V-28-3M. When crude V-28-3M is dissolved in acetone, an ... | 05/22/2001 |
| 6187810 | Macrocyclic compounds made from suboxide units The invention relates to macrocyclic substances which are bioregulatory active and a method for their synthetic production as well as its isolation from various starting materials. The application of these active substances as such or in combination with ... | 02/13/2001 |
| 6127157 | Coating material The present invention provides a coating suitable for coating woods, and the coating is obtained by dissolving proanthocyanidine into water or a water-containing alcohol.... | 10/03/2000 |
| 5969154 | Liquid crystalline diketopyrrolopyrroles A liquid crystalline compound of formula ##STR1## wherein B and D are each independently of the other C6 -C24 alkyl, ##STR2## L is ##STR3## methyl or C10 -C18 alkyl, wherein R1 is ... | 10/19/1999 |
| 5959157 | Process for making hydroxy-substituted ethynylated biphenyl compounds A process for making ethynylated, hydroxy-substituted biphenyl compounds comprising: a) halogenating 3,3'-dimethoxybiphenyl to form 2,2'-dihalo-5,5'-dimethoxybiphenyl; b) reacting the resulting 2,2'-dihalo-5,5'-dimethoxybiphenyl with a bromide-containing ... | 09/28/1999 |
| 5919768 | Di- and trivalent small molecule selectin inhibitors The present invention provides compounds having structure (II), and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof.... | 07/06/1999 |
| 5912363 | Method for extraction of proanthocyanidins from plant material A method for the extraction of proanthocyanidins from plant material is disclosed. The method involves heating an aqueous mixture of solid plant material, optionally under increased pressure and reduced oxygen; various separation, filtration and adsorptio... | 06/15/1999 |
| 5908581 | Red organic electroluminescent materials A red fluorescent material includes a compound of the formula: ##STR1## wherein: R1, and R2 are individually alkyl of from 1 to 20 carbon atoms, aryl, carbocyclic and other heterocyclic systems; and R3, and R4 a... | 06/01/1999 |
| 5908860 | Bicyclic compounds with pharmaceutical activity This invention relates to the method of treatment and/or prophylaxis of anxiety and/or disorders treatable and/or preventable with anti-convulsive agents, such as epilepsy, using compounds of the formula (Ia): ##STR1##... | 06/01/1999 |
| 5863773 | Antifungal corynecandin Disclosed are novel antifungal agents having the formula: ##STR1## as well as a pharmaceutically acceptable salt, ester of prodrug thereof, wherein R is: ##STR2## --C(O)--R1 wherein R1 is alkyl, alkenyl, aryl, arylalkenyl, ... | 01/26/1999 |
| 5854219 | 9-N-ethenyl derivatives of 9(S)-erythromycylamine The invention relates to 9-N-ethenyl derivatives of 9 (S)-erythromycylamine, new semisynthetic antibiotics of the macrolide class of the general formula (I) ##STR1## wherein R1 and R2 are the same or different and represent ... | 12/29/1998 |
| 5849216 | Compounds for use in liquid-crystal mixtures Compounds of the formula (I) R1 --(A1)a (--M1)b --(--A2)c (--M2)d (--A3)e (--M3)f (--A4)g --H(I... | 12/15/1998 |
| 5844000 | Propenone oxime ethers and pharmaceutical compositions containing them This invention relates to novel propenone oxime ethers, methods of preparing them and pharmaceutical compositions containing them. The compounds have the formula: ##STR1## wherein R1 is H, or glucuronide; R2 and R3 ar... | 12/01/1998 |
| 5811028 | Optically active dihydropyran derivative, and liquid crystal composition, liquid crystal device, and racemic mixture comprising the derivative A 2H-5,6-optically active dihydropyran derivative represented by the general formula (I) or (I'): ##STR1## wherein Rf represents a fluoroalkyl group having 1 or 2 carbon atoms; a liquid crystal composition and a liquid crystal device comprising the ... | 09/22/1998 |
