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| Number | Title | Issue Date |
| 7329687 | Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the structure of formula (I) | 02/12/2008 |
| 7318991 | Heterocycle-bearing onium salts The present invention relates to a heterocycle-containing onium salt useful as, for example, a cationic photopolymerization initiator and an acid generator for a chemically amplified resist, and provides “a heterocycle-containing onium salt shown in the specificat... | 01/15/2008 |
| 7244760 | Methods for preparation and use of psorospermin analogs Psorospermin is a cytotoxic dihydroflranoxanthone that has found to exhibit significant activity against various tumor cell lines. Unfortunately, psorospermin is no longer readily available from its natural plant source. The present invention is directed to a method... | 07/17/2007 |
| 7019024 | Pharmaceutical for treatment of neurological and neuropsychiatric disorders The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula: or a pharmaceutically acceptable salt thereof. ... | 03/28/2006 |
| 7015194 | Pharmaceutical composition comprising factor VIIa and anti-TFPI The present invention relates to the use of factor VIIa and TFPI inhibitor in the treatment or prophylaxis of bleeding episodes or coagulative treatment. ... | 03/21/2006 |
| 6384045 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxypyrone synthetic method is a simple con... | 05/07/2002 |
| 6204396 | Method for producing calcium fulvate from humus material A method produces calcium fulvate from naturally-occurring humus material, such as leonardite, or humic shales. The humus material containing solid fulvic acid and solid humic acid is mixed with water and sodium hydroxide for a first selected period of ti... | 03/20/2001 |
| 6147229 | Method for producing magnesium fulvate from humus material A method produces magnesium fulvate from naturally-occurring humus material, such as leonardite, or humic shales. The humus material containing solid fulvic acid and solid humic acid is mixed with water and sodium hydroxide for a first selected period of ... | 11/14/2000 |
| 6117869 | Compounds for and methods of inhibiting matrix metalloproteinases The present invention relates to compounds of Formula I that inhibit matrix metalloproteinases and to a method of inhibiting matrix metalloproteinases using the compounds ##STR1## More particularly, the present invention relates to a method of treati... | 09/12/2000 |
| 5981774 | Compounds for the treatment of hepatoma Compounds of general Formula I in which the substituents of R1 -R7 are hydrogen, hydroxy group, C1-6 alkyl group, C1-6 alkoxy group, or epoxypropoxy, but at the most, six of the substituents can simultaneously b... | 11/09/1999 |
| 5977077 | Xanthone analogs for the treatment of infectious diseases Therapeutic compositions for the treatment of infectious diseases are disclosed. These compositions comprise xanthones and xanthone derivatives, such as 2,3,4,5,6-pentahydroxyxanthone. Also disclosed are methods for the treatment of infectious diseases us... | 11/02/1999 |
| 5958970 | Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone ring. The tricyclic oxyprone synthetic method is a simple cond... | 09/28/1999 |
| 5883256 | Process for removing aromatic heterocyclic compounds product-containing solutions A process for removing aromatic heterocyclic compounds from a product-containing solution, in particular a protein solution, by bringing the solution into contact with a support material. The process is preferably carried out following a virus inactivatio... | 03/16/1999 |
| 5877030 | Process for creating molecular diversity and novel protease inhibitors produced thereby Methods for forming combinatorial libraries and the libraries produced thereby are provided. According to a preferred aspect of the invention, a plurality of core molecules are reacted with a plurality of different tool molecules to form a library of mole... | 03/02/1999 |
| 5741813 | Compounds for the treatment of hepatoma Compounds of general Formula I in which the substituents of R1 -R7 are hydrogen, hydroxy group, C1-6 alkyl group, C1-6 alkoxy group, or epoxypropoxy, but at the most, six of the substituents can simultaneously b... | 04/21/1998 |
| 5625081 | Fluorescent dye intermediates Intermediates for fluorescent dyes based on 9-carboxyethyl-6-hydroxy-3-oxo-3H-xanthene which are useful as reporters for reporter-labeled DNA fragments are described. The intermediates are protected fluorescent dyes bearing acyloxy groups at the 3 and 9 p... | 04/29/1997 |
| 5623080 | Fluorone and pyronin Y derivatives A compound of the formula (I) or (II): ##STR1## where R1, R2, R5 and R6 are the same or different and represent a hydrogen atom or a halogen atom and R1 and R2 may combine to form a ri... | 04/22/1997 |
| 5563169 | Tricyclic heterocyclic compound Constitution Tricyclic heterocyclyl compounds having a general formula (I): ##STR1## wherein: R1 and R2 each represents H, a lower alkyl or lower alkoxy group, a halogen atom or halogeno-lower alkyl; R3 represents H o... | 10/08/1996 |
| 5563278 | Angiotensin II antagonists This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their use for antagonizing angiotensin II receptors in mammals.... | 10/08/1996 |
| 5516794 | Xanthone derivatives, their preparation and use The novel compounds 3,6-Disubstituted xanthen-9-one of formula I ##STR1## in which R is a C3 -C8 linear, branched or cyclic alkyl and R1 is linear, branched C1 -C8 alkyl or cyclic C3 -... | 05/14/1996 |
| 5495005 | Synthesis and pharmacological activity of a series of novel xanthone derivatives A compound, and salts thereof, represented by either formula I or formula II below: (1) Formula I: ##STR1## wherein substituents R1 -R7 can be, independently, hydrogen, hydroxy group, C1-6 alkyl(oxy) group, acetyl est... | 02/27/1996 |
| 5409951 | Fungicidally active compounds Novel compounds of formula I ##STR1## wherein R1 is independently hydrogen, hydroxy, alkyl with 1 to 6 carbon atoms, acyloxy groups with 1 to 6 carbon atoms, alkyloxy with 1 to 6 carbon atoms or from 1 to 5 sugar moleties; and R2 | 04/25/1995 |
| 5380749 | Thioxanthenone antitumor agents 1-[[(Dialkylamino)alkyl]amino]-4-substituted-thioxanthen-9-ones are disclosed as antitumor agents. Compositions containing the thioxanthenones and methods of treating tumors and cancer in mammals with the thioxanthenones are also disclosed.... | 01/10/1995 |
| 5346917 | Thioxanthenone antitumor agents 1-[[(Dialkylamino)alkyl]amino]-4-substituted-thioxanthen-9-ones are disclosed as antitumor agents. Compositions containing the thioxanthenones and methods of treating tumors and cancer in mammals with the thioxanthenones are also disclosed.... | 09/13/1994 |
| 5300646 | Heterocyclic amine derivatives, their production and use A novel heterocyclic amine derivative of the general formula: ##STR1## wherein a ring A and a ring B stand independently for an optionally substituted benzene ring, Zo stands for O or S or ##STR2## stands for --CH2 --, X st... | 04/05/1994 |
| 5281620 | Compounds having antitumor and antibacterial properties The novel class of xanthenone-4-acetic acids represented by the general formula (I) ##STR1## where R1 represents up to two of the groups lower alkyl, halogen, CF3, CN, NO2, NH2, CH2 COOH, OR... | 01/25/1994 |
| 5264577 | Cyclic amino acids and derivatives thereof Novel cyclic amino acids which are useful in preparing biologically active peptides as well as a process for the preparation of D and L enantiomers of the cyclic amino acids are described where an N-protected derivative of the racemic cyclic amino acid is... | 11/23/1993 |
| 5176854 | Non-linear optical device According to the present invention, there is provided a non-linear optical device comprising a non-linear optical medium comprising an organic compound, which remarkably improves the non-linear optical properties. The non-linear optical device according t... | 01/05/1993 |
| 4999373 | Antihyperlipidemic and antiatherosclerotic compounds and compositions Certain N-2,6-dialkyl- or N-2,6-dialkoxyphenyl-N'-arylalkylurea compounds are potent inhibitors of the enzyme acyl CoA: cholesterol acyltransferase (ACAT), and are thus useful agents for the treatment of hypercholesterolemia or atherosclerosis.... | 03/12/1991 |
| 4999351 | 7-aryl and heteroaryl ethers of desacetylforskolin Novel forskolin derivatives, intermediates and processes for the preparation thereof, and methods for treating cardiac failure and memory deficit utilizing compounds or compositions thereof are disclosed.... | 03/12/1991 |
| 4927849 | Sulfonamido derivatives inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them The xanthosulfonamido and benzensulfonamido derivatives corresponding to the formula: ##STR1## wherein x represents hydrogen, alkyl, alkoxy or halogen, Y represents an alkyl, alkoxy or halogen and Z represents the group ##STR2## or Y and Z ... | 05/22/1990 |
| 4831052 | Flavone carboxylic acid derivatives Novel flavone carboxylic acid derivatives, intermediates therefor, and method for the preparation thereof, and their use in the differentiation of certain types of malignant cells, are all disclosed, certain of the novel compounds disclosed to be superior... | 05/16/1989 |
| 4816479 | Xanthone derivatives and process for producing the same Xanthone derivatives of the formula (I): ##STR1## wherein W, X, Y and Z which may be the same or different represent a hydrogen atom, a halogen atom or a lower alkyl group having 1 to 4 carbon atoms; A is a hydrogen atom B is a hydroxymethyl group, a... | 03/28/1989 |
| 4661607 | Furoxanthone derivatives useful as diuretics Xanthone derivatives of the formula (I): ##STR1## (wherein W, X, Y and Z which may be the same or different represent a hydrogen atom, a halogen atom or a lower alkyl group having 1 to 4 carbon atoms; A is hydrogen atom or together with Z forms a --C... | 04/28/1987 |
| 4585876 | Novel xanthones and thioxanthones Novel xanthones and thioxanthones of the formula I ##STR1## in which A, X, Y, Z, E and E' are as defined in patent claim 1, are described. A is preferably --S-- and E and E' are preferably bonded in the ortho-position relative to one another. The com... | 04/29/1986 |
| 4571405 | Anti-allergic chromone- or thiochromone-5-oxamic acid derivatives, compositions, and method of use therefor Certain 5-substituted chromones and thiochromones and pharmacologically acceptable salts thereof are disclosed. The compounds possess antiallergic properties and are represented by the formula: ##STR1## wherein: X is selected from the group consistin... | 02/18/1986 |
| 4539412 | 7-Hydroxylucanthone, 7-hydroxhycanthone and their analogs 7-Hydroxylucanthone and 7-hydroxyhycanthone derivatives have been found to have significant antitumor effect. The derivatives are of the general formula: ##STR1## wherein the radicals R1 and R2 are lower alkyl groups or other ... | 09/03/1985 |
| 4335046 | Polyester compositions, shaped articles obtained from them and processes for preparing them UV stable linear polyesters, e.g. PET, contain in their chain copolymerized bis(hydroxyalkoxy)xanth-9-ones, preferably 3,6-bis-(2-hydroxyethoxy)xanth-9-ones. The polymers are obtained by polymerization in the presence of a tetrahydroxy benzophenone, prefe... | 06/15/1982 |
| 4308210 | Nanaomycin B and therapeutic compositions containing same The present invention relates to new compound designated as nanaomycin B represented by general formula: ##STR1## Nanaomycin B is a quinone type and is active on mycoplasma, Gram-positive bacteria and trycophyton. This compound is useful as a medicam... | 12/29/1981 |
| 4299772 | Xanthenone-yl esters of phosphoric and phosphonic acids Disclosed are new compounds of the formula ##STR1## wherein R1 and R2 are each independently selected from the group consisting of halogen, alkyl, haloalkyl, nitro, alkylsulfinyl, alkylsulfonyl and cyano; k and m are integers fr... | 11/10/1981 |
