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Class 549/377 - The ring oxygens are in the 1,4-positions of the hetero ring (e.g., 1,4 dioxane, etc.)


Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which the hetero ring consists of two ring
No. of patents: 69
Last issue date: 10/28/2008


1    
NumberTitleIssue Date
7442793Peptide deformylase inhibitors
Novel PDF inhibitors and novel methods for their use are provided. ...
10/28/2008
7196108Bicyclic heterocycles for the treatment of diabetes and other diseases
The invention relates to certain bicyclic heterocycles havng the structure shown below which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, and atherosclerosis.
03/27/2007
7129355Process for preparing kifunensine intermediate and kifunensine therefrom
A novel method for the preparation of a compound of formula (I) from an N—protected-D-mannosamine. A compound of formula (I) is a useful intermediate for the preparation of kiftnensine, a potent and selective mannosidase inhibitor. The method includes protecting t...
10/31/2006
7101955Synthesis of energetic thermoplastic elastomers containing both polyoxirane and polyoxetane blocks
This thermoplastic elastomer is present in a substantially solid state suitable for use as a binder for a propellant, explosive, and/or gas generant of a supplemental restraint system. The thermoplastic elastomer is formed from a composition including A blocks which...
09/05/2006
6864254Inhibitor for 20-hete-yielding enzyme
An inhibitor for 20-hydroxyeicosatetraenoic acid production which comprises as the active ingredient a specific hydroxyformamidine derivative or a pharmacologically acceptable salt thereof. It is useful especially as a remedy for kidney diseases, cerebrovascular dis...
03/08/2005
6673934Primary intermediates for oxidative coloration of hair
Primary intermediates for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): ##STR1## wherein R is hydrogen, hydroxy, nitro, amino, halogen, C1 to C5 alkyl or haloalkyl, C1 to C5...
01/06/2004
6559144Bicyclic amino acids
Compounds of the formula I ##STR1## in which X, Y, Z, R1, R2, R3, R4, R5, R7, R8, R11, m and n have the meanings stated in claim 1, and their physiologically acceptabl...
05/06/2003
6540793Coupler for use in oxidative hair dyeing
Couplers for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): ##STR1## wherein R is selected from the group consisting of C1 to C2 alkyl and hydroxyethyl; R1 is selected from the gr...
04/01/2003
6329027Chlorobenzene derivatives, liquid-crystal composition, and liquid-crystal display elements
Provided are liquid crystalline compounds having excellent physical properties and being excellent in miscibility with other liquid crystal materials; liquid crystal compositions comprising the crystalline compound; and liquid crystal display device fabri...
12/11/2001
6274613Cyclic imines as pesticides
The invention relates to novel cyclic imines of the formula (I) ##STR1## in which Ar1 and Ar2 each represent substituted phenyl and n represents 1, to a process for their preparation and to their use as pesticides....
08/14/2001
6063939Process for preparing unsaturated cyclic ethers
Unsaturated cyclic ethers of the formula I ##STR1## where Z is --(CHR4)q -- or --(CHR4)q --O--, q is 0, 1, 2 or 3 and R1,R2,R3,R4 are hydrogen or C1 -C4
05/16/2000
6040339Urea derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use
Compounds of formula (I): ##STR1## wherein: R1 is alkyl; R2a, R2b, R2c and R2d are the same or different and each is hydrogen, optionally substituted alkyl or various other organic groups; R...
03/21/2000
6037482Process for catalytic addition of nucleophiles to alkynes or allenes
A process for the catalytic addition of nucleophilic agents to alkynes or allenes to form alkenes substituted by the nucleophile which may further react with the nucleophile and/or isomerize comprises using a catalyst comprising a wholly or partly ionized...
03/14/2000
6022895Substituted amino compounds and their use as substances having an analgesic effect
Substituted amino compounds of general formula (I) ##STR1## are described, as are a method of preparing them and their use as drugs, especially as analgesics....
02/08/2000
5880147Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use
Compounds of formula (I): ##STR1## wherein: R1 is alkyl; R2a, R2b, R2c and R2d are the same or different and each is hydrogen, optionally substituted alkyl, --(C.dbd.O)--B1 (wherein B
03/09/1999
5718845Tricyanovinyl substitution process for NLO polymers
Nonlinear optical compounds which contain a heteroaromatic ring and may further comprise a tricyanovinyl group attached to the heteroaromatic ring....
02/17/1998
5709820Alkenyl cyclohexane derivatives and liquid crystal compositions
Liquid crystalline alkenyl cyclohexane compounds of formula (I) having a nematic phase over a broad temperature range, a higher elastic constant ratio K33 /K11 and a lower viscosity, liquid crystal compositions comprising the above c...
01/20/1998
5698715Preparation of unsaturated cyclic ethers
A process for the preparation of unsaturated cyclic ethers of the general formula I ##STR1## in which Z denotes --(CHR4)q or --(CHR4)q --O-- q is 0, 1, 2 or 3 and R1, R2, R3, and...
12/16/1997
5688972Preparation of acetals
A process for the preparation of acetals by reacting one or more ethylenically unsaturated compounds with carbon monoxide, hydrogen and a liquid or dissolved organic nucleophilic compound containing at least two vicinal hydroxy groups in the presence of a...
11/18/1997
5565436Production stimulators of nerve growth factors comprising cyathane derivatives
A production stimulator of nerve growth factor contains a new cyathane derivative of the form ##STR1## where R is either CHO or CH2 OH....
10/15/1996
5562808Method and apparatus for decontaminating a liquid surfactant of dioxane
A method and apparatus are disclosed for decontaminating a liquid surfactant of a dioxane having a vapor pressure which is higher than the surfactant. A contaminated liquid surfactant is directed through an inclined conduit. A gas is directed into the inc...
10/08/1996
54059889-substituted bicyclo[3.3.0]octane derivatives, process for their production and their pharmaceutical use
The invention relates to 9-substituted bicyclo[3.3.0]octane derivatives of formula I, ##STR1## and their salts with physiologically compatible bases, as well as the ଱-, ଲ- or γ-cyclodextrin clathrates, as well as the compounds of fo...
04/11/1995
5391544Cyathane derivatives and antimicrobial agents containing same
New cyathane derivatives shown by Formula (1) or (2) given below have the effect of stimulating production of nerve growth factors and antimicrobial effects: ##STR1## where R is either CHO or CH2 OH....
02/21/1995
5278301Route to glycals in the allal and gulal series
Axial anomeric sulfoxides generated via thiophenol Ferrier rearrangement of glucal and galactal derivatives are used to synthesize glycals of the gulal and allal series. An application of the method led to the synthesis of the esperamicin thiosugar....
01/11/1994
5258406Sulfonimidamides
This invention provides certain sulfonimidamide compounds, formulations and method of use of these compounds in treating susceptible neoplasms....
11/02/1993
5104982Route to glycals in the allal and gulal series
Axial anomeric sulfoxides generated via thiophenol Ferrier rearrangement of glucal and galactal derivatives are used to synthesize glycals of the gulal and allal series. An application of the method led to the synthesis of the esperamicin thiosugar....
04/14/1992
5104985Labdane process
Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed....
04/14/1992
5091521Cis-platinum complexes, a process for the preparation thereof, and pharmaceuticals containing these compounds
Compounds of the general formula I ##STR1## in which R1 represents a hydrogen atom or an alkyl group of the formula CH3 (CH2)n --where n=0 to 5, R2 represents a hydrogen atom when X is a carbamoyl gro...
02/25/1992
5081263Dioxane adducts of aromatic meta- or para-hydroxy-carboxlic acids
The invention relates to the dioxane adducts of armoatic meta-or para-hydroxycarboxylic acids, which consist, per mole, of 1 mole of 1,4-dioxane and about 2 moles of hydroxycarboxylic acid. The invention further relates to a process for the preparation of...
01/14/1992
5077037Novel compositions for magnetic resonance imaging
Methods and compositions for enhancing magnetic resonance imaging in at least a portion of a warm-blooded animal....
12/31/1991
5070211Dioxo heterocyclic compounds, composition containing same and process for plant growth regulation using same
A compound having the structural formula ##STR1## where R is at least one of hydrogen, C1 -C4 alkyl, C1 -C4 alkoxy, halogen, cyano, phenyl, phenoxy, benzyl or COOR1 ; and R1 is C1...
12/03/1991
5047558Process for the preparation of a dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid
The invention relates to the dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid which adduct comprises 1 mol of 1,4-dioxane and about 2 mol of 2-hydroxynaphthalene-6-carboxylic acid per mol. The invention further relates to a process for the prepara...
09/10/1991
5003089Preparation of cyclic 6-membered to 8-membered vinylene-1,2-dioxy compounds
Cyclic 6-membered to 8-membered 1,2-vinylenedioxy compounds of the general formula I ##STR1## where A is ##STR2## R1 to R7 independently of one another are each hydrogen, C1 -C8 -alkyl, C2
03/26/1991
4988827Ether isonitriles and radiolabeled complexes thereof
Ether-substituted isonitriles, Tc99m complexes thereof, and processes for myocardial tissue radioimaging using the Tc99m complexes....
01/29/1991
4980503Conversion of glycol formates to monocarboxylic acids
It has been surprisingly discovered in accordance with the present invention that glycol formates and their alkyl ether derivatives can be substantially selectively converted to monocarboxylic acids by bringing a glycol formate or an alkyl ether derivativ...
12/25/1990
4978430Method for dehydration and concentration of aqueous solution containing organic compound
An improved method for dehydration and concentration of an aqueous solution containing an organic compound is disclosed. The solution is evaporated to produce a gaseous mixture comprising an organic compound vapor and a water vapor. The water vapor is sel...
12/18/1990
4948469Separation of formic acid from dioxane by extractive distillation with amides
Dioxane cannot be completely removed from dioxane and formic acid mixtures by distillation because of the presence of the maximum azeotrope. Dioxane can be readily removed from dioxane - formic acid mixtures by extractive distillation in which the extract...
08/14/1990
4925959Dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid and process for the preparation thereof
The invention relates to the dioxane adduct of 2-hydroxynaphthalene-6-carboxylic acid which adduct comprises 1 mol of 1,4-dioxane and about 2 mol of 2-hydroxynaphthalene-6-carboxylic acid per mol. The invention further relates to a process for the prepara...
05/15/1990
4889939Fluoropolyethers containing end groups endowed with anchoring capacity
Compounds suitable for being used as lubricants, having general formula: (I) RO--(C3 F6 O)m --(CFXO)n --CFX--L, or (II) R"CFXO--(C3 F6 O)x (CFXO)y --(C2 F4 ...
12/26/1989
4866188Synthesis of cyclic ethers
A process is disclosed for preparing a cyclic ether which comprises cyclodehydrating a polyhydroxy compound of the general formula in which R1 and R3, each of which is the same or different, is hydrogen or a lower aliphatic, cycloaliphati...
09/12/1989
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