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Class 549/365 - The ring oxygens are in the 1,2- or 1,3-positions of the hetero ring


Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which the hetero ring consists of two ring
No. of patents: 107
Last issue date: 06/10/2008


1      
NumberTitleIssue Date
7385067Process for the preparation of compounds having a CFO bridge
The invention relates to a process for the preparation of compounds containing at least one —CF2—O— bridge in the molecule, in which a) an acid is added onto at least one ketene dithioketal, b) the...
06/10/2008
73718746-Alkylamino-2-methyl-2′-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative as anti-inflammatory inhibitor
The present invention relates to a noble 6-alkylamino-2-methyl-2′-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative, a method for preparing the same with high efficiency using a parallel synthetic method, one of combinatorial chemical synthetic t...
05/13/2008
73685756-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor
When a multi-step process reaction is carried out in a solution, it generally requires several treatments and purification procedures to go through with after the reaction, however, the inventive method for preparing 2,2′-disubstituted-3,4-dihydro-7,8-disubstitute...
05/06/2008
7294725Process for preparing salmeterol
A process for the preparation of a compound of formula (I) or a single enantiomer thereof, or a salt or a solvate thereof, wherein W is a chiral auxiliary or hydrogen and P1 and P2 are each ...
11/13/2007
7256218Biguanide and dihydrotriazine derivatives
Biguanide and dihydrotriazine derivatives, preferably substituted asymmetrical imidodicarbonimidic diamides derived from hydroxylamines, and compositions containing biguanide and dihydrotriazine derivatives are disclosed. In addition, methods of using the biguanide ...
08/14/2007
7157510Method of nucleating a polyolefin composition with acetal-based compounds
An acetal-based composition useful as a nucleating, gelling, thickening or clarifying agent is disclosed. The composition may be synthesized or provided in many different forms, including multicarbon diacetals formed from carbohydrates. Once synthesized, the compoun...
01/02/2007
7125853Bicyclic carbohydrate compounds useful in the treatment of infections caused by sp., such as hepatitis C and bovine viral diarrhea viruses
We describe the use of bicyclic carbohydrates for the treatment of hepatitis C virus infections. Different bicyclic carbohydrates were tested in vitro against DNA-viruses, retro-viruses and Flaviviridae sp., an important family of human and animal RNA pathoge...
10/24/2006
7125854Bicyclic carbohydrates as antiprotozoal bioactive for the treatment of infections caused by parasites
The use of bicyclic carbohydrates for the treatment of parasite infections is described. Different bicyclic carbohydrates have been tested in vitro against a number of protozoa. These compounds also have been screened against viruses, tumors, bacteria and fungi. Com...
10/24/2006
7098243Bicyclic carbohydrates as antiviral bioactives for the treatment of infections caused by the alphaherpesvirinae HSV-1 and HSV-2
Novel bicyclic carbohydrate compounds are effective for the prophylaxis and treatment of diseases caused by infections of the alphaherpesvirinae HSV-1 and HSV-2. The invention includes the compound wherein X...
08/29/2006
7019003Peptide deformylase inhibitors
Novel PDF inhibitors and novel methods for their use are provided. ...
03/28/2006
675637510-Aryl-11h-benzo[b]fluorene derivatives and analogs for medicinal use
The invention provides for a non-steroidal compound having the formula wherein Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2— or —CH2C...
06/29/2004
6706744Glucagon antagonists/inverse agonists
Novel compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any diseases and disorders, wherein...
03/16/2004
6583161Benzenesulfonamides and benzamides as therapeutic agents
The invention provides compounds, compositions and methods relating to novel aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particul...
06/24/2003
64107903-amin3-arylpropan-1-ol compounds, their preparation and use
3-amino-3-arylpropan-1-ol compounds of formula I: ##STR1## R1 and R2 independently denoting C1-6 alkyl, or together denoting a (CH2)2-6 ring optionally substituted by phenyl, R3 denoting C3...
06/25/2002
6407100Fungicidal aromatic oximes
The invention relates to novel compounds of the formula ##STR1## in which R1 is C1-4 alkyl and (Y--X) is CH2, C1-2 alkylthio-CH.dbd. or C1-2 alkyl-ON.dbd. and Z is an aldimino or ketimino group, and t...
06/18/2002
6365756Process for the production of optically enriched (R)- or (S)-albuterol
A process for the production of optically enriched (R)- or (S)-albuterol or (R)- or (S)-albuterol salts by the resolution of a novel ketal derivative 2-(N-t-butylamino)-1-(+2,2-dimethyl-1,2-benzodioxin-6-yl) ethanol, with a chiral tartaric acid derivative...
04/02/2002
6355634Aromatic compounds
The invention relates to novel compounds of the formula ##STR1## in which R1 is C1-4 alkyl and (Y--X) is CH2, C1-2 alkylthio-CH.dbd. or C1-2 alkyl-ON.dbd. and Z is an aldimino or ketimino group, and t...
03/12/2002
6331627Intermediates of benzoxazinone derivatives and preparation thereof
The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptab...
12/18/2001
6310080Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
Selected amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, rela...
10/30/2001
6277867Pesticide compounds, compositions and process for the preparation thereof
The invention relates to compounds of general formula (I), their optically active isomers and salts wherein Ar=alycylic, aromatic or one or more heteroatom containing heterocyclic moiety, optionally substituted by one or more alkoxy-, methylenedioxy-, alk...
08/21/2001
6274613Cyclic imines as pesticides
The invention relates to novel cyclic imines of the formula (I) ##STR1## in which Ar1 and Ar2 each represent substituted phenyl and n represents 1, to a process for their preparation and to their use as pesticides....
08/14/2001
5998667Substituted biphenyl oxazolines
The invention relates to new substituted biphenyloxazolines of the formula (I) ##STR1## in which R1 represents C1 -C6 -halogenoalkylthio and R2 represents hydrogen, or R1 and R2 together wi...
12/07/1999
5952386Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production
The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen...
09/14/1999
5869702Polyol ether derivatives and production methods therefor
Polyol ether derivatives, a method for producing the polyol ether derivatives, and a working fluid composition for a refrigerating machine containing a hydrofluorocarbon and a refrigeration oil containing the polyol ether derivatives as a base oil....
02/09/1999
5773463Indane and tetrahydronaphthalene derivatives as calcium channel antagonists
This invention describes the use of aminoindane and amino-tetrahydronaphthalene derivatives of general formula (I) ##STR1## in which Ar, X, R1, R2 and n are defined in claim 1, for the manufacture of a medicament for the treatme...
06/30/1998
56123811,2-ethanediol derivative and salt thereof process for producing the same, and cerebral function-improving agent comprising the same
This invention relates to a 1,2-ethanediol derivative and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebro...
03/18/1997
5578252Photochromic substituted naphthopyran compounds
Described are novel reversible photochromic 3H-naphtho[2,1-b]pyran compounds, examples of which are substituted with an oxy-bearing substituent at the number 8 carbon atom and with either an alkyl group at the number 7 carbon atom or with a carbonyl beari...
11/26/1996
5569669Alkylaminoindane compounds
The invention relates to a compound selected from those of formula (I): ##STR1## in which R1, R2, R2', R2", R2'", R3 and n are as defined in the description, an optical isomer, and an addit...
10/29/1996
5569640Substituted 1,3-benzadioxane-4-ones and 1,3-benzathioxane-4-ones, their preparation and their conversion to crop protection agents
Cyclic acetals of the formula I ##STR1## where the substituents have the following meanings: R1 and R2 are hydrogen, unsubstituted or substituted alkyl or phenyl; additionally R1 and R2 together are an unsu...
10/29/1996
5514588Surfactant-nutrients for bioremediation of hydrocarbon contaminated soils and water
The present invention provides for enhanced bioremediation of hydrocarbon contaminated soils and waters by treating soil or water with a composition comprising a phosphorous source, a diluent and a compound or mixtures thereof represented by the structura...
05/07/1996
5475132Antifungal agents based on amides containing a phenyl group
R3, R4 and R5, each represents a hydrogen or halogen atom (at least one of R3, R4 and R5 being other than hydrogen or halogen); optionally substituted amino; optionally halogenated or hydro...
12/12/1995
54729841,2-ethanediol derivative and salt thereof and cerebral function-improving agent comprising the same
This invention relates to a 1,2-ethanediol derivative and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebro...
12/05/1995
5440051Process for the ଱-chlorination of aryl ethers
Aryl ethers are chlorinated in the ଱-position by a process in which they are metered into a reaction vessel at the same time as chlorine, the reaction being carried out at temperatures in the range from 60° to 150° C....
08/08/1995
5420333Lignan analogues, methods of preparation thereof and anti-hyperlipemic agents
An anti-hyperlipemic agent which has a potent activity of reducing LDL and VLDL cholesterols, which are thought to be a risk factor for arteriosclerosis among total blood cholesterols, and which is excellent in the antioxidant activity on LDL, is provided...
05/30/1995
5420273Condensed heterocyclic compounds
The invention relates to compounds of the formula ##STR1## wherein R1 is hydrogen, acyl, lower-alkyl or --CHO, --CH2 OR10, --COR7 or OR13 ; R2, R3 and R4 are, ind...
05/30/1995
5360815Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, ...
11/01/1994
5356924Pesticidal benzodioxole
Compounds of the general formula: ##STR1## wherein R1 and R2 each independently represents a halogen atom or an alkyl, alkoxy, haloalkyl, haloalkoxy, alkoxycarbonyl, alkenoxy, cyano or nitro group; R3 and R4
10/18/1994
5312831Urethanes and ureas that induce cytokine production
The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Com...
05/17/1994
5292748Process for the production of substituted vinylbenzenes
A process for the production of substituted vinylbenzenes of the general formula: ##STR1## wherein R is a lower alkyl group having 1 to 4 C atoms, R1 is hydrogen or an acetyl group and R2 is hydrogen, a lower alkyl group ha...
03/08/1994
5274176Process for the production of substituted vinylbenzenes
A process for the production of substituted vinylbenzenes of the general formula: ##STR1## wherein R is a lower alkyl group having 1 to 4 C atoms, R1 is hydrogen or an acetyl group and R2 is hydrogen, a lower alkyl group ha...
12/28/1993
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