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...When G.G. Hubbard learned of his future son-in-law's invention, he called it "only a toy." His daughter was engaged to a young man named Alexander Graham Bell.
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| Number | Title | Issue Date |
| 7825266 | Extraction of fulvic minerals from humic substances The present invention provides a method for extracting fulvic acid from complexes of humic substances. The fulvic acid extract is safe for human and animal consumption and for application to plant foliage. As a result of the extraction method, the fulvic acid extrac... | 11/02/2010 |
| 7763742 | Hexahydro-4H-indeno acetonide fragrance compound A novel compound 4H-indeno[1,2-D]-1,3-dioxole, 3a,3b,5,6,7,8a-hexahydro-2,2,3a,3b,7,7-hexamethyl 1 is disclosed as well as the use of the compound as a fragrance chemical. The fragrance compound is suitable for use in creating fragrances, and scents in items such as... | 07/27/2010 |
| 7605277 | Aminodibenzodioxin derivative and organic electroluminescent using the same This invention relates to a highly reliable material for an organic electroluminescent element exhibiting high luminance, high luminous efficiency, little deterioration in emission, and suitability for use and storage at high temperatures and to an organic electrolu... | 10/20/2009 |
| 7419986 | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, pre... | 09/02/2008 |
| 7335666 | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, pre... | 02/26/2008 |
| 7329637 | Methylene dioxy octahydroindene derivatives The present invention is directed to a novel dioxin compound and the use of the novel compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products. ... | 02/12/2008 |
| 7288543 | Opioid receptor antagonists A compound of the formula (I) (I) wherein the variables X1 to X6, Ra, Rb, R1 to R7 including R3′, E, p, j, y, z, A, B and C are as described or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the trea... | 10/30/2007 |
| 7208142 | Indanylidene compounds Novel indanylidene compounds can be used as UV-A filters in cosmetic compositions for protecting skin and hair and for technical applications. ... | 04/24/2007 |
| 7135479 | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans Compounds of the Formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress di... | 11/14/2006 |
| 7122513 | Hexahydro-4H-indeno acetonide fragrance compound A novel compound 4H-indeno[1,2-D]-1,3-dioxole,3a,3b,5,6,7,8a-hexahydro-2,2,3a,3b,7,7-hexamethyl 1 is dislosed as well as the use of the compound as a fragrance chemical. The fragrance compound is suitable for use in creating fragrances, and scents in items such as p... | 10/17/2006 |
| 7071359 | Neuropathy improvers containing nitrogenous compounds as the active ingredient A compound represented by the Formula below, and an agent for the remedy of neural damage having the said compound as the active ingredient. [Here, G represents G1 shown below | 07/04/2006 |
| 6784292 | Method for the production of imidazo-(1,2-C)(2,3)-benzodiazepines and intermediates in the production thereof The invention relates to a method for the preparation of compound of formula (1). The invention further relates to the previously unknown compounds of formulas (5 and 6) as intermediates in the production of benzodiazepines of formula (1). ... | 08/31/2004 |
| 6720431 | Methods and apparatus for separating and detecting specific polyhalogenated diaromatic hydrocarbons Sample processing methods that utilize a graphitised carbon matrix are useful for determining the relative amounts polyhalogenated biphenyls (PHBs), polyhalogenated dibenzofurans (PHDFs), and polyhalogenated dibenzo-p-dioxins (PHDDs) in a mixture of polyhalogenated ... | 04/13/2004 |
| 6696577 | Method of producing organic acids for use as an electrolyte in producing high ionization concentrations of precious metals A method of preparing organic acids (fulvic, humic, and ulmic) for use as an electrolyte for producing high ionizations of precious metals (such as silver) which entails leaching out the organic acid from its source, stabilizing the organic acid first wit... | 02/24/2004 |
| 6635437 | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes Novel heterocyclic compounds which generate chemiluminescence on reaction with a phosphatase enzyme are provided as well as a process for their preparation and intermediates useful therein. The compounds comprise a nitrogen, oxygen or sulfur-containing he... | 10/21/2003 |
| 6566521 | Valeraldehyde and process for its preparation Bidentate phosphine ligands of the formula ##STR1## wherein the substituents are as defined in the specification and a process for preparing linear aldehydes by hydroformylating internal olefins using such phosphine ligands.... | 05/20/2003 |
| 6342605 | Valeraldehyde and process for its preparation Bidentate phosphine ligands of the formula ##STR1## wherein the substituents are as defined in the specification and a process for preparing linear aldehydes by hydroformylating internal olefins using such phosphine ligands.... | 01/29/2002 |
| 6340704 | Cell differentiation inducing amide derivatives, their production and use The present invention provides a compound represented by the formula: ##STR1## wherein R1 is an amino group which may be substituted; R2 is a hydrogen atom or a lower alkyl group which may be substituted; X is a methyne group which m... | 01/22/2002 |
| 6303798 | Methylene dioxy tetrahydroindane derivative The present invention is directed to a novel dioxin compound and the use of the novel compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products.... | 10/16/2001 |
| 6201004 | Dioxino derivatives and their use as therapeutic agents Compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof in which A is methylene or --O--; B is methylene or --O--; G1 --G2 --G3 form a heteroaromatic or heteroaliphatic chain; g is 0, 1 or 2; U is an ... | 03/13/2001 |
| 6117869 | Compounds for and methods of inhibiting matrix metalloproteinases The present invention relates to compounds of Formula I that inhibit matrix metalloproteinases and to a method of inhibiting matrix metalloproteinases using the compounds ##STR1## More particularly, the present invention relates to a method of treati... | 09/12/2000 |
| 6037367 | Substituted-pent-4-ynoic acids Compounds of formula (I) wherein: R1 is --(CR4 R5)n C(O)O(CR4 R5)m R6, --(CR4 R5)n C(O)NR4 (CR4 R5)m | 03/14/2000 |
| 6031115 | Process for preparing epoxides A process for preparing compounds of formula (B) wherein: one of A1 ' or A2 ' represents hydrogen and the other represents a group CF3 --Y-- wherein Y represents --CF2 --, >C.dbd.O, or --CH(OH)--, or A1 ' ... | 02/29/2000 |
| 6020503 | Process for producing 1,4-benzodioxane derivatives An industrial method for preparation of a 1,4-benzodioxane derivative (1), which comprises reacting a diol compound (2) with a carbonating agent to prepare a carbonate compound (3) and after removal of the protective group, cyclizing it by heating or by t... | 02/01/2000 |
| 5922771 | Benzocycloalkene compounds, their production and use A compound of the formula ##STR1## wherein R1 and R2 independently represent H or an optionally substituted hydrocarbon group; R3 represents an optionally substituted hydrocarbon group; R4 represents H or a... | 07/13/1999 |
| 5869490 | Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one The compounds of formula I: ##STR1## wherein X is H2 or O; R1 is hydrogen, hydroxy, halo, trifluoromethyl, trifluoromethoxy, alkyl, alkoxy, aralkoxy, alkanoyloxy, amino, mono- or di-alkylamino, alkanamido or alkanesulfonamido; Z... | 02/09/1999 |
| 5854010 | Bioassay for detecting 2,3,7,8-tetrachlorodibenzo-para-dioxin and TCDD-like compounds and novel recombinant cell line useful therefor A recombinant cell line deposited at the American Type Culture Collection under ATCC accession number CRL-12286, also known as the mouse H1L1.1 cell line, has been made by using genetic engineering techniques for inserting dioxin responsive elements upstr... | 12/29/1998 |
| 5847167 | Carbamoyloxlabdanes Novel carbamoyloxylabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure and treating cardiac failure utilizing compounds and compositions thereof are disclosed.... | 12/08/1998 |
| 5843988 | Cyclopropachromencarboxylic acid derivatives The present invention provides novel cyclopropachromen-carboxylic acid derivatives having an antagonistic activity against metabotropic glutamate receptors and its pharmaceutically acceptable salts. Cyclopropachromen-carboxylic acid derivatives and its ph... | 12/01/1998 |
| 5708018 | 2-aminoindans as selective dopamine D3 ligands Compounds and their pharmaceutically acceptable salts suitable for treating central nervous system disorders associated with the dopamine D3 receptor activity of Formula I: ##STR1## wherein R1 and R2 are independently chosen fro... | 01/13/1998 |
| 5512686 | Method for the purification of dioxydiphthalic anhydride and ester intermediate made therein Crude mixtures of dioxydiphthalic anhydride containing alkali metal salts are purified by treating the crude mixture with an alkanol, such as n-butanol, to form the dioxydiphthalic acid diester; removing the insoluble alkali metal salts by filtration; rem... | 04/30/1996 |
| 5498419 | Fumarate salt of 4-(diethyl-3-(1-methyloctyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibe nzo[b,d]pyran-1-ol, 4-(diethyl-amino) butyric The present invention provides the fumarate salt of 4-(diethyl-3-(1-methyloctyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenz o[b,d]pyran-1-ol, 4-diethyl-amino)butyric acid ester, i.e. the compound having the following structure (I): ##STR1## an... | 03/12/1996 |
| 5376630 | Methyl, substituted propyl-substituted pentamethyl indane derivatives, processes for producing same and perfumery uses thereof Described are methyl, substituted propyl-substituted pentamethyl indane derivatives defined according to the structure: ##STR1## wherein R1 represents hydroxyl or methyl; R2 represents hydrogen, chloro or OR6 ; and R | 12/27/1994 |
| 5276053 | Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.... | 01/04/1994 |
| 5272144 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use Aryloxy- and heteroaryloxy-alkylene derivatives of amines of formula ##STR1## wherein each of A and B is a group of formula (i) to (iii): ##STR2## wherein Y is --O--, --S-- or --NR-- in which R is hydrogen or C1 -C6 alkyl;... | 12/21/1993 |
| 5183924 | Derivatives of benzocycloalkenyldihydroxyalkanoic acids, processes of preparation and medications containing them Derivatives of benzocycloalkenyldihydroxyalkanoic acids, inhibitors of HMG CoA reductase, antagonists of thromboxane A2 receptors and antifungals, denoted by the formula I ##STR1## in which X=CH2, O or S; R1 and R | 02/02/1993 |
| 5166404 | Dioxydiphthalic acid esters Oxydiphthalic acid esters of the formula ##STR1## where Z is H or alkyl, and X is halo, X' is H or halo, or X and X' together represent an oxygen atom; are prepared by the esterification reaction of the corresponding halo-oxydiphthalic anhydride or ... | 11/24/1992 |
| 5153227 | Phenylsulfonyl nitromethanes as aldose reductase inhibitors The invention concerns novel pharmaceutical compositions for use in the treatment of certain complications of diabetes and galactosemia and which contain a nitromethane derivative (or its non-toxic salt) as active ingredient. The nitromethane derivatives ... | 10/06/1992 |
| 5071853 | Polycyclic amines useful as cerebrovascular agents A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of cerebrovascular disorders are disclosed.... | 12/10/1991 |
| 5070103 | Naphthalene derivatives and composition and methods of use, and aldehyde intermediates Naphthalene derivative of the formula: ##STR1## wherein R1 is hydrogen atom or a lower alkoxycarbonyl and R2 is a lower alkoxycarbonyl, or R1 and R2 are combined together to form a group of the formula: ##S... | 12/03/1991 |
