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| Number | Title | Issue Date |
| 8153827 | Reagents for biomolecular labeling, detection and quantification employing Raman spectroscopy The present disclosure provides isotopically substituted compounds of the formula (I): wherein T, U, V, W, X, Y, Z, R0, R3, R4, R5 and R6 are as defined in the detailed... | 04/10/2012 |
| 8048850 | Covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins and methods of use In one aspect, the invention provides covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins. In some embodiments, the covalent conjugates comprise artelinate and holotransferrin. In another aspect, the invention provides methods fo... | 11/01/2011 |
| 7692030 | Conjugates of artemisinin-related endoperoxides and hydrazone derivatives for the treatment of cancer Compounds having an artemisinin-related endoperoxide moiety covalently coupled to a hydrazone moiety through a linker. Compositions and methods for treating cancer using the compounds. ... | 04/06/2010 |
| 7361727 | Copolymerization of 1,4-dioxan-2-one and a cyclic ester monomer producing thermal stabilized 1,4-dioxan-2-one (co)polymers A polymerization process to derive a thermal-stabilized poly(1,4-dioxan-2-one) and cyclic ester monomer copolymer using a coordination-insertion catalyst/initiator. 1,4-dioxan-2-one and cyclic ester monomer, each containing less than 100-ppm water and having an acid... | 04/22/2008 |
| 7291565 | Method and system for treating a substrate with a high pressure fluid using fluorosilicic acid A method and system is described for treating a substrate with a high pressure fluid, such as carbon dioxide in a supercritical state. A process chemistry is introduced to the high pressure fluid for treating the substrate surface. The process chemistry comprises fl... | 11/06/2007 |
| 7151152 | Crosslinked body and method of producing the same and method of recycling the same This invention relates to a novel crosslinked body obtained by crosslinking plural polymers and having higher characteristics and being easily decrosslinked, and particularly to a crosslinked body obtained by crosslinking plural polymers through mechanical bonding w... | 12/19/2006 |
| 7112685 | Labeled resiniferatoxin derivatives This invention relates resiniferatoxin derivatives useful in a vanilloid receptor binding assay and methods for production thereof. ... | 09/26/2006 |
| 7097768 | Coconut mesocarp-based biofilter material and its use in a wastewater treatment system A biofilter material for biofiltering a fluid is disclosed. This biofilter material comprises fragments of coconut mesocarp. A wastewater treatment system is also disclosed and comprises a filter bed and a water distribution system. The filter bed comprises fragment... | 08/29/2006 |
| 7091338 | Purification of 4,4′(5′)- di-t-butylcyclohexano-18-crown-6 A purification method is disclosed for a predetermined water-insoluble extractant present in a liquid phase composition that additionally contains one or more additional extractants, synthesis reaction starting materials, and reaction byproducts dissolved as solutes... | 08/15/2006 |
| 7060749 | Polyester composition, films made thereof and process for producing the composition A polyester composition includes a ligand capable of coordinating to a metal or metal ion, wherein the ligand includes at least one donor atom selected from the group consisting of a nitrogen atom, a sulfur atom, and an oxygen atom. Consequently, it is possible to i... | 06/13/2006 |
| 7060422 | Method of supercritical processing of a workpiece An apparatus for supercritical processing and non-supercritical processing of a workpiece comprises a transfer module, a supercritical processing module, a non-supercritical processing module, and a robot. The transfer module includes an entrance. The supercritical ... | 06/13/2006 |
| 7044662 | Developing photoresist with supercritical fluid and developer An apparatus for developing a polymeric film without the need for a water rinse step is disclosed. An object having a surface supporting a polymeric film is placed onto a support region within a pressure chamber of the apparatus. A fluid and developer is introduced ... | 05/16/2006 |
| 7022664 | 1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones The invention relates to 1,2-substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones and to the use of these compounds in fragrance compositions. ... | 04/04/2006 |
| 7022866 | Phosphonites Phosphonites I of the formula 1 or 2 where R1, R2 are each, independently of one another, hydrogen, an alkyl or alkylene group having from 1 to 8 carbon atoms or an alkoxy group having from 1 to 8 carbon at... | 04/04/2006 |
| 6926012 | Method for supercritical processing of multiple workpieces An apparatus for supercritical processing of multiple workpieces comprises a transfer module, first and second supercritical processing modules, and a robot. The transfer module includes an entrance. The first and second supercritical processing modules are coupled ... | 08/09/2005 |
| 6924345 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions A polymeric, phosphorus-containing composition made by heating, in the presence of an initiator, preferably a free radical initiator, and optionally in the presence of one or more comonomers, at least one substituted phosphonylated 2,2′-dihydroxyl-1,1′-binaphtha... | 08/02/2005 |
| 6920443 | Method, system, program, and data structure for transforming database tables Disclosed is a method, system, program, and data structure for transforming data in an input table in a database in a server in communication with a client. A transform command is received from the client indicating an input data table name in the database and at le... | 07/19/2005 |
| 6784292 | Method for the production of imidazo-(1,2-C)(2,3)-benzodiazepines and intermediates in the production thereof The invention relates to a method for the preparation of compound of formula (1). The invention further relates to the previously unknown compounds of formulas (5 and 6) as intermediates in the production of benzodiazepines of formula (1). ... | 08/31/2004 |
| 6710074 | Compound having antimalarial activity An object of the present invention is to provide a novel compound having antimalarial acitivity and an antimalarial agent containing the novel compound as an active component. An antimalarial agent containing 12-hidroxy-2-(1-methoxy-carbonylethyl)-5-oxo-10,11,13-tri... | 03/23/2004 |
| 6677463 | Single pot conversion of artemisinin to artesunic acid The present invention provides a single pot process for the preparation of artesunic acid from artemisinin involving reduction followed by esterification of the reduced product at room temperature.... | 01/13/2004 |
| 6521769 | Chiral phosphines, transition metal complexes thereof and uses thereof in asymmetric reactions Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include chiral C1-C6 TunaPhos ligands. The ruthenium TunaPhos complex reduces ketones to the corresponding alcohols... | 02/18/2003 |
| 6403347 | HIV integrase inhibitors Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts... | 06/11/2002 |
| 6025458 | Degradable polydioxaneone-based materials Disclosed are degradable materials including molded products, laminates, foams, nonwoven materials, adhesives, coatings and films, and particularly packaging films. The materials are made using polydioxaneone polymers comprising at least two different dio... | 02/15/2000 |
| 5990321 | Monoesters and macrocyclic diester of phthalic acid and synthesis thereof Monoesters and macrocyclic diesters of 2,2,4-trimethyl-1,3-pentanediol and phthalic acid or a derivative thereof are described. Methods by which such monoesters and diesters may be prepared are also described. The mono- and diesters according to the inven... | 11/23/1999 |
| 5981772 | Hydrocyanation of diolefins and isomerization of nonconjugated 2-alkyl-3-monoalkenenitriles Improved liquid phase process useful in the hydrocyanation of diolefinic compounds to produce nonconjugated acyclic nitrites and to the liquid phase process of isomerization of the nitrites to, among other things, 3- and/or 4-monoalkene linear nitrites. T... | 11/09/1999 |
| 5969074 | Reaction of perfluoroolefins with Bis (Silyl) ethers to produce fluorinated compounds A reaction of perfluoroolefins with bis(silyl) ethers to produce novel partially fluorinated and perfluorinated copolymers and macrocyclic compounds is disclosed.... | 10/19/1999 |
| 5922771 | Benzocycloalkene compounds, their production and use A compound of the formula ##STR1## wherein R1 and R2 independently represent H or an optionally substituted hydrocarbon group; R3 represents an optionally substituted hydrocarbon group; R4 represents H or a... | 07/13/1999 |
| 5917047 | Heterocyclic compounds The present invention relates to novel N-substituted amino alcohols, amino acids and acid derivatives thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing... | 06/29/1999 |
| 5888398 | Composition and process for separating cesium ions from an acidic aqueous solution also containing other ions A crown ether cesium ion extractant is disclosed as is its synthesis. The crown ether cesium ion extractant is useful for the selective purification of cesium ions from aqueous acidic media, and more particularly useful for the isolation of radioactive ce... | 03/30/1999 |
| 5843869 | Inhibitors of hydroxyphenylpyruvate dioxygenase and an assay for identification of inhibitors There are described a method for enriching the anabolic p-hydroxyphenylpyruvate dioxygenases from plant tissues and a method by means of which the enzymatic activity of the enzyme can be measured in a simple manner without complete purification of the enz... | 12/01/1998 |
| 5840925 | Trioxane dimer compounds having antiproliferative and antitumor activities Described herein are novel trioxane dimers of structure ##STR1## which possess antiproliferative and antitumor activities.... | 11/24/1998 |
| 5811420 | Fungarrestins Compounds of formula (I), ##STR1## wherein R1 and R2 are independently hydrogen, unsubstituted lower alkyl or lower alkyl substituted by lower alkoxy or lower alkyl thio, or acyl which is unsubstituted or substituted by one or m... | 09/22/1998 |
| 5801223 | Degradable polydioxaneone-based materials Disclosed are degradable materials including molded products, laminates, foams, nonwoven materials, adhesives, coatings and films, and particularly packaging films. The materials are made using polydioxaneone polymers comprising at least two different dio... | 09/01/1998 |
| 5767222 | Degradable polydioxaneone-based materials Disclosed are degradable materials including molded products, laminates, foams, nonwoven materials, adhesives, coatings and films, and particularly packaging films. The materials are made using polydioxaneone polymers comprising at least two different dio... | 06/16/1998 |
| 5750732 | Method to produce cyclic esters Disclosed is a novel integrated process for production of cyclic esters which includes recovery of starting materials, such as lactic acid from a dilute aqueous lactic acid-containing solution, by solvent extraction. The starting materials are then formed... | 05/12/1998 |
| 5734067 | Anti-oxidative tricyclic, condensed heterocyclic compound Providing a novel tricyclic, condensed heterocyclic compound having an anti-oxidative action and being promising for use in pharmaceutical agents, cosmetics, chemical products and the like. By chemical synthesis, a novel anti-oxidative, tricyclic, condens... | 03/31/1998 |
| 5719182 | Endothelin receptor anatagonists Novel indane and indene derivatives are described which are endothelin receptor antagonists.... | 02/17/1998 |
| 5675021 | Method to produce and purify cyclic esters Methods are provided for the production, recovery and purification of cyclic esters. Such methods include producing a cyclic ester composition containing at least one impurity, contacting the cyclic ester composition with at least one adsorbent to remove ... | 10/07/1997 |
| 5663193 | Inhibitors of farnesyl-protein transferase The present invention is directed to non-peptide compounds which inhibit farnesyl-protein transferase (FPTase) and the farnesylation of the oncogene protein Ras. The invention also relates to the process for the preparation of a compound of this invention... | 09/02/1997 |
| 5589446 | Process for removal of ionic salt deposits A composition and method for the removal of ionic salt deposits from a surface using an organic solvent of low polarity and a complexing agent. The complexing agent is chosen from a group which includes podands, cryptands, and coronands. The method provid... | 12/31/1996 |