...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7906659 | Carbocyclic and oxacarbocyclic fumaric acid oligomers The present invention relates to certain carbocyclic and oxacarbocyclic fumaric acid oligomers and the use thereof for preparing a pharmaceutical preparation as well of pharmaceutical preparations containing these compounds. ... | 03/15/2011 |
| 7696361 | Chemical reagents capable of selective attachment to and reaction with peptides and proteins Biomimetic reagents capable of selectively forming non-covalent complexes and initiating intermolecular reactions with peptides in the gas phase are described. The reagents are particularly useful in gas phase peptides chemistry. ... | 04/13/2010 |
| 7662977 | PI-3 kinase inhibitor prodrugs The invention provides novel prodrugs of inhibitors of PI-3 kinase. The novel compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine. ... | 02/16/2010 |
| 7282066 | Processes for preparing and using tanning agents and preservatives A process for the preparation of aqueous formulations, and aqueous formulations so prepared, the process comprising heating at least one cyclic compound of the formula I in the presence of water and of an acidic ... | 10/16/2007 |
| 7276628 | Biologically active complex The invention relates to an aqueous solution containing at least one species selected from the group consisting of a 1:1 molar complex of TeO2 with a moiety of formula (A) and ammonium salts thereof: HO—X—OH (A); where X is an optionally substituted d... | 10/02/2007 |
| 7214538 | Device and method for the determination of lithium ion concentration in a biological fluid The present invention relates to a novel device and method for the detection of lithium ions in a biological fluid. In a preferred embodiment, the present invention provides a novel compound and a optical sensor which incorporates said compound for the detection of ... | 05/08/2007 |
| 7169942 | Cannabinoid derivatives, methods of making, and use thereof 1′-substituted cannabinoid derivatives of delta-8-tetrahydrocannabinol, delta-9-tetrahydrocannabinol, and delta-6a-10a-tetrahydrocannabinol that have affinity for the cannabinoid receptor type-1 (CB-1) and/or cannabinoid receptor type-2 (CB-2). Compounds having ac... | 01/30/2007 |
| 7166226 | Ion exchange cryptands covalently bound to substrates One embodiment of the invention comprises an ion exchange composition formed by reacting unsaturated carbon to carbon moieties pendant from derivatized ion binding cryptands with a support substrate under free radical activation conditions to form a covalent bond th... | 01/23/2007 |
| 7045150 | Tellurium containing nutrient formulation and process for enhancing the cumulative weight gain or feed efficacy in poultry A novel nutrient formulation containing tellurium for use in poultry, and a method of feeding it which improves subsequent livability, cumulative feed efficacy or weight gain is disclosed. ... | 05/16/2006 |
| 7026363 | Alkoxylated polyglycerols and their use as demulsifiers The present invention relates to the use of alkoxylated polyglycerols preparable by polycondensation of glycerol and subsequent alkoxylation for demulsifying water-oil emulsions, in particular in the production of crude oil from crude oil/water emulsions. The invent... | 04/11/2006 |
| 7022664 | 1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones The invention relates to 1,2-substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones and to the use of these compounds in fragrance compositions. ... | 04/04/2006 |
| 6949537 | PI-3 kinase inhibitor prodrugs The invention provides novel prodrugs of inhibitors of PI-3 kinase. The novel compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine. ... | 09/27/2005 |
| 6914109 | Process for the preparation of 15-pentadecanolide The invention relates to a process for the preparation of 15-pentadecanolide by hydrogenating 15-pentadecenolide and to its use. ... | 07/05/2005 |
| 6905668 | Diagnostic agents for pancreatic exocrine function The present invention provides a 13C-labeled oligosaccharide or polysaccharide or a salt thereof excluding U-13C-maltose, 13C-starch, 1-13C-maltotetraose and 1-13C-amylose; a derivative of the 13C-lab... | 06/14/2005 |
| 6867295 | Ion exchange cryptands covalently bound to substrates One embodiment of the invention comprises an ion exchange composition formed by reacting unsaturated carbon to carbon moieties pendant from derivatized ion binding cryptands with a support substrate under free radical activation conditions to form a covalent bond th... | 03/15/2005 |
| 6743564 | Amine compounds, resist compositions and patterning process Amine compounds having a cyano group are useful in resist compositions for preventing a resist film from thinning and also for enhancing the resolution and focus margin of resist. ... | 06/01/2004 |
| 6590048 | Highly active cationic ruthenium and osmium complexes for olefin metathesis reactions The present invention describes the use of cationic vinylidene, allenylidene and higher cumulenylidene complexes of ruthenium or osmium as catalysts or catalyst precursors for olefin metathesis reactions of all types, as well as to new cationic allenylide... | 07/08/2003 |
| 6544945 | Cyclic pro-perfumes having modifiable fragrance raw material alcohol release rates The present invention relates to cyclic pro-perfumes comprising a moiety derived from a fragrance raw material alcohol. Such cyclic perfumes may contain dioxolane and glucosyl orthesters that are suitable for use in delivering enhanced fragrance longevity... | 04/08/2003 |
| 6482565 | Photoresist cross-linker and photoresist composition comprising the same The present invention relates to a cross-linker for use in a photoresist which is suitable for a photolithography process using KrF (248 ru), ArF (193 nm), E-beam, ion beam or EUV light source. According to the present invention, preferred cross-linkers c... | 11/19/2002 |
| 6376457 | Phenoketals and the use thereof as odoriferous substances Phenone ketals corresponding to formula (I): ##STR1## where X and Y independently of one another represent methoxy, ethoxy, propoxy or butoxy groups and R1 is a methyl, ethyl or propyl group, R2 is hydrogen or a methyl, ethyl, isopro... | 04/23/2002 |
| 6369099 | Method of locking 1 -OH of vitamin D compounds in axial orientation A method of modifying or altering the structure of a 1-hydroxylated vitamin D compound to increase its biological activity by altering the conformational equilibrium of the A-ring to favor a chair conformation that presents the 1-hydroxyl in... | 04/09/2002 |
| 6323238 | Benzopyranyl guanidine derivatives, process for preparation thereof, and pharmaceutical compositions containing them The present invention relates to novel benzopyranyl guanidine derivatives of the formula 1, process for preparation therof and pharmaceutical use of the benzopyranyl guanidine derivatives. The benzopyranyl guanidine derivatives of the present invention ca... | 11/27/2001 |
| 6313322 | Method for producing 3-methyl 2-butenal acetals A process for preparing acetals of the formula I ##STR1## where a) the Rs are, independently of one another, a C1 -C20 -alkyl or C3 -C20 -alkenyl radical, or b) the two R radicals together form the members of an unsu... | 11/06/2001 |
| 6294390 | Covalently immobilized fluoroionophores for optical ion sensors Compounds, constructed in modular manner, of formula (I), ##STR1## wherein I is the monovalent residue of an ionophore, F is the monovalent residue of a fluorophore, G is a functional group, T is a trivalent organic radical and R01, R02 and R | 09/25/2001 |
| 6211228 | Compositions and methods for treating mast-cell mediated conditions Novel compounds, compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders are described. The compounds, compositions and methods are effective for the prevention and treatment of inflammatory disease... | 04/03/2001 |
| 6194589 | Production of amide derivatives and intermediate compounds therefor A method for producing an amide derivative of the formula [XV] ##STR1## wherein each symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing said compound and a production method thereof. The product... | 02/27/2001 |
| 6166225 | Processes for producing dialdehyde monoacetals In a method of producing a dialdehyde monoacetal(s) (III) from dialdehyde(s) (I) and diol(s) (II), the present invention provides a method comprising a first step wherein said dialdehyde(s) (I) and said diol(s) (II) are reacted to produce dialdehyde bisac... | 12/26/2000 |
| 6133461 | Process for producing amide derivatives and intermediates therefor A method for producing an amide derivative of the formula [XV] ##STR1## wherein each symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing said compound and a production method thereof. The pr... | 10/17/2000 |
| 6117413 | Radionuclide-binding compound, a radionuclide delivery system, a method of making a radium complexing compound, a method of extracting a radionuclide, and a method of delivering a radionuclide The invention pertains to compounds which specifically bind radionuclides, and to methods of making radionuclide complexing compounds. In one aspect, the invention includes a radionuclide delivery system comprising: a) a calix[n]arene-crown-[m]-ether comp... | 09/12/2000 |
| 6017849 | Synthesis methods, complexes and delivery methods for the safe and convenient storage, transport and application of compounds for inhibiting the ethylene response in plants The present invention generally relates to the regulation of plant physiology, in particular to methods for inhibiting the ethylene response in plants or plant products, and has three embodiments. The first embodiment relates to methods of minimizing impu... | 01/25/2000 |
| 5969074 | Reaction of perfluoroolefins with Bis (Silyl) ethers to produce fluorinated compounds A reaction of perfluoroolefins with bis(silyl) ethers to produce novel partially fluorinated and perfluorinated copolymers and macrocyclic compounds is disclosed.... | 10/19/1999 |
| 5962704 | Production of amide derivatives and intermediate compounds therefor A method for producing an amide derivative of the formula XV! ##STR1## wherein each symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing said compound and a production method thereof. The p... | 10/05/1999 |
| 5922863 | Diene cyclization using ruthenium and osmium carbene complexes Disclosed are ruthenium and osmium carbene compounds which are stable in the presence of a variety of functional groups and which can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins. Specifically, the present inven... | 07/13/1999 |
| 5792876 | Process for producing acetals A process is described for producing acetals comprising reacting an aldehyde or a ketone with an alcohol in the presence of a titanium compound having an acetylacetone as a ligand, or in the presence of a compound selected from the group consisting of sta... | 08/11/1998 |
| 5721305 | Polyglycerol production Glycerol, 2,2-dimethyl-1,3-dioxolane-4-methanol (Solketal), glycidol or glycerol carbonate is polymerized into preponderantly linear oligomers at 150° C. to 350° C. in the presence of anionic clay material, preferably hydrotalcite, as a catalyst.... | 02/24/1998 |
| 5718845 | Tricyanovinyl substitution process for NLO polymers Nonlinear optical compounds which contain a heteroaromatic ring and may further comprise a tricyanovinyl group attached to the heteroaromatic ring.... | 02/17/1998 |
| 5717113 | Bioactive acetogenins and derivatives Novel acetogenins isolated from Asimina triloba and Goniothalamus giganteus of the family Annonaceae and derivatives of those and other acetogenins are described. Bioactive cyclic formaldehyde acetal derivatives are prepared from Annonaceous acetogenins h... | 02/10/1998 |
| 5698715 | Preparation of unsaturated cyclic ethers A process for the preparation of unsaturated cyclic ethers of the general formula I ##STR1## in which Z denotes --(CHR4)q or --(CHR4)q --O-- q is 0, 1, 2 or 3 and R1, R2, R3, and... | 12/16/1997 |
| 5672624 | Endoperoxides useful as antiparasitic agents The present invention relates to novel biologically-active organic peroxides and to novel uses of both known and new organic peroxides. More specifically, this invention details organic endoperoxides having antiparasitic activity, methods for their prepar... | 09/30/1997 |
| 5635529 | Sulfonamidodioxepanes, methods of preparation, intermediates, salts and use thereof Novel O-substituted or O-unsubstituted 6-sulfonamido-1,3-dioxepane-5-ols having hypoglycemic activity are obtained from 6-amino-1,3-dioxepane-5-ol, tetrahydro-6H-[1,3]-dioxepino[5,6-d]oxazole, 5,6-epoxy-1,3-dioxepane or N-sulfonyl-tetrahydro-1H,4H-[1,3]-d... | 06/03/1997 |