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| Number | Title | Issue Date |
| 7417156 | Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers In only two steps and in 65% overall yield, natural trioxane artemisinin (I) was converted on gram scale into C-10-carba trioxane dimer (3). This new, very stable dimer was then transformed easily in one additional step into four different dimers (4-7). Alcohol and ... | 08/26/2008 |
| 7220870 | Hydrolytic kinetic resolution of cyclic substrates The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisome... | 05/22/2007 |
| 6995276 | Cyclic disulfide compound, process of producing the same and optical product comprising the same A compound capable of giving optical materials that may be high in both refractive index and Abbe's number and may be excellent in heat resistance and transparency, and a process that may produce the same with good efficiency are disclosed. The compound may be a cyc... | 02/07/2006 |
| 6992196 | Method for producing refined ethylene sulfite Refined ethylene sulfite exhibits an excellent storage stability when used as a constituent of an electrolyte. A method of producing same has a step of reacting ethylene glycol and thionyl chloride to producing raw ethylene sulfite, a rectifying step for rectifying ... | 01/31/2006 |
| 6566525 | Preparation of N-substituted-hydroxycycloalkylamine derivatives A process for the preparation of N-substituted-hydroxycycloalkylamine derivatives, that are useful intermediates for the synthesis of various organic chemicals including pharmaceutical and agrochemical compounds, represented by formula (1), by reacting a ... | 05/20/2003 |
| 6469146 | Radiopharmaceutical products suitable for the selective labeling of lymphocytes, and their preparation The invention concerns radiopharmaceutical products suitable for the selective labeling of lymphomas containing a metal complex with the formula: [M(R1 CS2)(R1 CS3)2 ] in which M is chosen from among ... | 10/22/2002 |
| 6392067 | Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive int... | 05/21/2002 |
| 6316180 | Electrochemiluminescent monitoring of compounds/electrochemiluminescence assays Detectable compounds comprising a chemically-transformable first compound covalently linked to an electrochemiluminescent compound are provided. Such compounds are useful in processes and kits that monitor the status of the first compound and derive infor... | 11/13/2001 |
| 5917056 | 10-deacetyl-14ଲ-hydroxybaccactine III derivatives, a process for the preparation thereof and formulations containing them The present invention relates to novel 10-deacetyl-14ଲ-hydroxybaccatine III derivatives. The novel derivatives, having cytotoxic and antitumour activity, are prepared from this synton after functionalization of the hydroxyls at 1-, 14- as thioc... | 06/29/1999 |
| 5869697 | Process for preparing diltiazem A compound of formula (IV) ##STR1## wherein R1 is hydrogen, an alkyl, alkoxy, alkylamino, alkylthio, aryl, aryloxy, or halogen residue; R is an alkyl, or aryl residue, and X is S or C, which is a valuable intermediate for producing Diltiaz... | 02/09/1999 |
| 5643713 | Electrochemiluminescent monitoring of compounds Detectable compounds comprising a chemically-transformable first compound covalently linked to an electrochemiluminescent compound are provided. Such compounds are useful in processes and kits that monitor the status of the first compound and derive infor... | 07/01/1997 |
| 5641623 | Electrochemiluminescence assay A rapid single step assay suitable for the detection or quantification of ଲ-lactam antibiotics and ଲ-lactamases. The assay can be performed directly on samples of food, such as milk and meat, blood or serum and is useful in determining the sui... | 06/24/1997 |
| 5488115 | Alcohols Novel alcohols of the formula ##STR1## wherein Ra is azido or phthalimido, R4 is alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, R7 and R8 together are a trimethylene or tetramethylene group which is o... | 01/30/1996 |
| 5336683 | Antioxidants The invention is concerned with novel antioxidants, namely the [R] and, respectively, [S] compounds of the formula ##STR1## wherein R1 and R2 together represent the --S(O)-- group and R3 and R4 represent hy... | 08/09/1994 |
| 5321143 | Ruthenium-catalyzed production of cyclic sulfates A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various su... | 06/14/1994 |
| 5286899 | Process for the stereoselective transformation of a diol to an alcohol An efficient and commercially-viable method for the stereoselective transformation of a diol to an alcohol is disclosed. The present method is particularly well-suited for the preparation of the unnatural D-isomer of malic acid or its derivatives from the... | 02/15/1994 |
| 5223531 | 1,3,2-dioxathiolan-s-oxide derivatives, method for preparation, and use therefor Disclosed is a 1,3,2-dioxathiolan-S-oxide derivative as represented by the general formula (I): ##STR1## (where R1 and R2 are identical to or different from each other and each is a hydrogen atom or a lower alkyl group; X is a h... | 06/29/1993 |
| 5214056 | 1,3,2-dioxathiolane oxide derivative A 1,3,2-dioxathiolane oxide derivative is represented by the following formula: ##STR1## wherein X represents --S(O)-- or --S(O)2 --; R1 represents a hydrogen atom, an alkali metal atom, a benzyl group, or a lower alkyl group; R... | 05/25/1993 |
| 5189200 | Process for the stereoselective transformation of a diol to an alcohol An efficient and commerically-viable method for the stereoselective transformation of a diol to an alcohol is disclosed. The present method is particularly well-suited for the preparation of the unnatural D-isomer of malic acid or its derivatives from the... | 02/23/1993 |
| 5162554 | Optically active enantiomers of substituted glyceraldehydes or glycidaldehydes formed as subtituted 1,5- dihydro-3H-2,4-benzodioxepines Stable, optically active enantiomers of substituted glyceraldehydes or glycidaldehydes are synthesized by using osmium-catalyzed asymmetric dihydroxylation of an olefin which is a substituted 1,5-dihydro-3H-2,4-benzodioxepine. For example, the protected ... | 11/10/1992 |
| 5112990 | Ruthenium-catalyzed production of cyclic sulfates A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various su... | 05/12/1992 |
| 5023342 | Cyclic sulfate compounds A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various su... | 06/11/1991 |
| 4960904 | Process for the preparation of cyclic sulphates Cyclic sulphates of formula: ##STR1## are prepared by oxidation of a cyclic sulphite of formula: ##STR2## with a hypohalite of an alkali or alkaline-earth metal and a catalytic quantity of a ruthernium derivative (RuO2, RuCl3 | 10/02/1990 |
| 4924007 | Process for the preparation of cyclic sulphates Cyclic sulphates of formula ##STR1## in which R1, R2, R3, R4, R5, and R6, which are identical or different, each denote hydrogen, halogen, alkyl, alkoxy, aryloxy or alkoxycarbonyl and ... | 05/08/1990 |
| 4841070 | Sulfinyl-ascorbic acid useful as an anti-oxidant The novel 5,6-sulfinyl-L-ascorbic acid and its stereoisomers, their manufacture by sulfinylating L-ascorbic acid or corresponding stereoisomers, compositions having oxidation-inhibiting properties which contain 5,6-sulfinyl-L-ascorbic acid or a stereoisom... | 06/20/1989 |
| 4761486 | Cyclohexenone derivatives, the preparation and use thereof as herbicides and plant growth regulators Cyclohexenone derivatives of the formula ##STR1## where R1, R2, A and X have the meanings given in the disclosure, a process for their manufacture, herbicidal and plant growth-regulating agents containing the novel active ingred... | 08/02/1988 |
| 4725682 | Biocidal sulfur-containing bis-imino carbamate compounds Sulfur-containing bis-amino carbamate compounds exhibit outstanding acaricidal, nematocidal and insecticidal activity.... | 02/16/1988 |
| 4666502 | Herbicidal N-thienyl-chloroacetamides The invention provides 5-membered heteroaromatic compounds of formula I wherein Ar is a 5-membered heteroaromatic group comprising 1 or 2 heteroatoms selected from O, S and N and linked by a ring C-atom to the N-atom of the N(Y)COCH2 Cl group to whi... | 05/19/1987 |
| 4617151 | 2- or 2,3-substituted 5,6,11,12-tetrathiotetracene and 5,6,11,12-tetraselenotetracene 2- or 2,3-substituted 5,6,11,12-tetraseleneotetracene or -tetrathiotetracene of the formula ##STR1## in which X is S or Se, R is alkoxy, hydroxyalkoxy, aryloxy, cycloalkoxy, aralkoxy, --OH, --NH2, --Cl, --Br or substituted amino and Y is ... | 10/14/1986 |
| 4386214 | Process for the preparation of cyclic perfluoroaliphaticdisulfonic acid anhydrides Cyclic perfluoroaliphaticdisulfonic acid anhydrides, sulfonamide derivatives thereof, a process for making the same, curable compositions containing cyclic perfluoroaliphaticdisulfonic acid anhydrides or sulfonamide derivatives thereof and cationically-se... | 05/31/1983 |
| 4329478 | Cyclic perfluoroaliphaticdisulfonic acid anhydrides Cyclic perfluoroaliphaticdisulfonic acid anhydrides, sulfonamide derivatives thereof, a process for making the same, curable compositions containing cyclic perfluoroaliphaticdisulfonic acid anhydrides or sulfonamide derivatives thereof and cationically-se... | 05/11/1982 |
| 4259507 | 3,5-Di-(2-methylpropyl)-1,2,4-trithiolane and uses thereof for augmenting or enhancing the flavor or aroma of a foodstuff 3,5-di-(2-methylpropyl)-1,2,4-trithiolane having the formula: ##STR1## and its "cis" and "trans" isomers represented by the structures: ##STR2## and described as being useful in augmenting or enhancing the organoleptic properties (taste and arom... | 03/31/1981 |
| 4005104 | Products from the reaction of sulfur trioxide with acyclic internal vic-dialkoxypolyfluoroalkenes Selected novel vic-dialkoxyperfluoroalkyl-vic-diol cyclic sulfates, e.g., 2,3-dimethoxyhexafluorobutane-2,3-diol cyclic sulfate, useful for preparing the corresponding perfluoro--diketones, e.g., hexafluorobiacetyl (known), are synthesized by react... | 01/25/1977 |
| 3978225 | Heterocyclic homoprostanoidal derivatives Heterocyclic homoprostanoidal derivatives are prepared. These compounds have valuable antiprostaglandin activity specifically inhibiting prostaglandin synthesis and antagonizing diarrhea induced by prostaglandin E2 (PGE2).... | 08/31/1976 |
