Class 549/338 - Plural five-membered hetero rings

Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which contain at least two five-membered oxygen
No. of patents: 25
Last issue date: 01/10/2012

Number	Title	Issue Date
8093410	Intermediates and methods for the synthesis of halichondrin B analogs Methods of synthesizing intermediates useful for the synthesis of halichondrin B analogs are described. ...	01/10/2012
7385067	Process for the preparation of compounds having a CFO bridge The invention relates to a process for the preparation of compounds containing at least one —CF2—O— bridge in the molecule, in which a) an acid is added onto at least one ketene dithioketal, b) the...	06/10/2008
6660766	Anti-first-pass effect compounds Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for inhibiting the first pass effect....	12/09/2003
6147076	Analogues of N-acetylardeemin, method of preparation and uses thereof The present invention provides a compound having the structure: ##STR1## wherein R1 R6 and R7 are independently hydrogen, OH, NH2, SH, halogen, C1 -C9 linear or branched chain alkyl, a...	11/14/2000
6124477	Anti-first-pass effect compounds The present inventor has discovered chemical compounds which inhibit the first-pass effect of orally administered drugs in humans; that phototoxic low molecular weight furocoumarins and certain ether-substituted furocoumarins that are naturally present in...	09/26/2000
5703249	Bicycloaliphatic 2-methylene-1,3-dioxepanes The present invention relates to novel bicycloaliphatic 2-methylene-1,3-dioxepanes, which are suitable as starting materials for the preparation of polymers and copolymers, preferably of composite and dental materials. The 2-methylene-1,3-dioxepanes accor...	12/30/1997
5258402	Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates Imidate derivatives of sulfamates having the following formula (I): ##STR1## wherein R1, R2, R3, R4 and X are as herein defined have been found to be useful prodrug and exhibit anticonvulsant activity when ...	11/02/1993
4792606	Process for the preparation of dimeric aromatic acyl cyanides A process for the preparation of a dimeric aromatic acyl cyanide of the formula ##STR1## in which Ar is optionally substituted phenyl, naphthyl or hetaryl, comprising reaction an acyl halide of the formula in which Hal is fluorine, chlorine or bromine, wi...	12/20/1988
4737493	7-((substitu ted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro(4,5)decanes as analgesic agents Substituted phenoxy-, 1-, and 2-naphthalenyloxy-, indenyl-, indolyl-, benzofuranyl-, and benzo[b]thiofuranylcarboxamides of 7,8-(substituted-diamino)-1-oxaspiro[4.5]decanes are useful as analgesic agents. A method of making the compounds, pharmaceutical c...	04/12/1988
4582916	Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol Sulfamates of the following formula (I): ##STR1## wherein X is O or CH2 and R1, R2, R3, R4 and R5 are as herein defined have been found to exhibit anticonvulsant activity and are thus ...	04/15/1986
4513006	Anticonvulsant sulfamate derivatives Sulfamates of the following formula (I): ##STR1## wherein X is O or CH2 and R1, R2, R3, R4 and R5 are as herein defined have been found to exhibit anticonvulsant activity and are thus ...	04/23/1985
4409391	Process to produce anthracycline compounds There is presented a process for the manufacture of hexahydronaphthacene derivatives of the general formula ##STR1## wherein one of R1 and R2 represents a hydrogen atom and the other represents a hydrogen atom or a hydroxy group...	10/11/1983
4393221	Process to produce hexahydronaphthacene derivatives There is presented a process for the manufacture of hexahydronaphthacene derivatives of the general formula ##STR1## wherein one of R1 and R2 represents a hydrogen atom and the other represents a hydrogen atom or a hydroxy group...	07/12/1983
4316985	Cyclic compounds There is presented a process for the manufacture of hexahydronaphthacene derivatives of the general formula ##STR1## wherein one of R1 and R2 represents a hydrogen atom and the other represents a hydrogen atom or a hydroxy group...	02/23/1982
4207240	4,5-Seco-estrane-3,5,17-trione derivatives Novel 4,5-seco-estrane-3,5,17-trione derivatives of the formula ##STR1## wherein R1 is alkyl of 1 to 3 carbon atoms, R2 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms and K and K' are individu...	06/10/1980
4080334	Intermediates in the total synthesis employing substituted isoxazole derivatives The intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-norsteroids. Further, the intermediates and processes of the invention provide a route for the preparation of pharmaceutica...	03/21/1978
4044004	Total steroid synthesis employing substituted isoxazole derivatives The novel intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-norsteroids. Further, the intermediates and processes of the invention provide a novel route for the preparation of p...	08/23/1977
4012420	9,10-Secoestrane derivatives and their production 9,10-Secoestranes, useful as intermediates in the total synthesis of steroids, of the formula ##STR1## WHEREIN N IS 1 OR 2, R1 is lower alkyl, R2, R3 and R4 are hydrogen, alkoxy or acyloxy, X is free or ket...	03/15/1977
4001302	9,10-Secoestrane derivatives and their production 9,10-Secoestranes, useful as intermediates in the total synthesis of steroids, of the formula ##STR1## WHEREIN N IS 1 OR 2, R1 is lower alkyl, R2, R3 and R4 are hydrogen, alkoxy or acyloxy, X is free or ket...	01/04/1977
3998847	9,10-Secoestrane derivatives and their production 9,10-Secoestranes, useful as intermediates in the total synthesis of steroids, of the formula ##STR1## wherein n is 1 or 2, R1 is lower alkyl, R2, R3 and R4 are hydrogen, alkoxy or acyloxy, X is free or ket...	12/21/1976
3985771	Total steroid synthesis employing substituted isoxazole derivatives The novel intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-nor-steroids. Further, the intermediates and processes of the invention provide a novel route for the preparation of ...	10/12/1976
3976701	Process for the preparation of 9,10-secoestrane derivatives 6,9-Oxido-9,10-seco-1,3,5(10),6,8,14-estrahexaenes, useful as intermediates in the total synthesis of steroids, of the formula ##SPC1## Wherein n is 1 or 2, R1 is lower-alkyl, R2, R.sub. 3 and R4 are H, alkoxy or acyloxy, ...	08/24/1976
3974182	Intermediates for the preparation of trienic steroids Novel intermediates for the preparation of trienic steroids which intermediates have the formula ##SPC1## Wherein R is alkyl of 1 to 4 carbon atoms and X is selected from the group consisting of aliphatic of 1 to 6 carbon atoms optionally substituted and ...	08/10/1976
3965124	6,9-Oxido-9,10-secoestrane derivatives and method of synthesis 6,9-Oxido-9,10-seco-1,3,5(10),6,8,14-estrahexaenes, useful as intermediates in the total synthesis of steroids, of the formula ##SPC1## Wherein n is 1 or 2, R1 is lower-alkyl, R2, R3 and R4 are H, alkoxy or acyl...	06/22/1976
3943151	Prostaglandin intermediates A new synthesis of key prostaglandin precursors and intermediates employed in their preparation. The novel synthetic sequence of this invention is shorter and more efficient than those previously employed to prepare to key intermediate....	03/09/1976

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Class 549/338 - Plural five-membered hetero rings