Class 549/331 - The spiro includes a hetero ring

Subclass of Class 549 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein at least one of the rings in the spiro
No. of patents: 137
Last issue date: 03/04/2008

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Number	Title	Issue Date
7338962	Spirocyclic heterocyclic derivatives and methods of their use Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the δ opioid receptor and may be us...	03/04/2008
7323577	Process for producing benzofuran derivative A novel process for efficiently and easily producing a compound represented by the formula: wherein ring A is a benzene ring that may be optionally further substituted in addition to the group represented by W, o...	01/29/2008
7256170	Spiro compounds as perfuming ingredients The present invention relates to the perfumery industry. It concerns more particularly an alcohol, ester, ether or ketone derivative having a spiro-type skeleton, the latter being substituted by short alkyl groups. The invention also relates to the use of the invent...	08/14/2007
7247262	Photochromic compositions and light transmissible articles The invention related to a photochromic polymeric composition comprising a polymer matrix and a photochromic compound which is an adduct comprising a photochromic moiety and at least one pendant oligomer group to provide a rate of fade of the photochromic polymeric ...	07/24/2007
7205417	Spiro compounds Compounds of the formula (I): (wherein A is an optionally substituted straight-chain hydrocarbon having 1 to 6 carbon atoms, which is optionally intervened by oxygen or nitrogen...	04/17/2007
7160852	Polyalklbicylic derivatives The compound according to the formula set forth below and the use of the compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products is disclosed. ...	01/09/2007
7094368	Pyrano-quinolines, pyrano-quinolinones, combinations thereof, photochromic compositions and articles Described are compositions of at least one material represented by a pyrano[3,2-c]quinoline structure, a pyrano[3,2-c]quinolinone structure or mixtures thereof. The pyrano[3,2-c]quinoline structure is characterized by having a nitrogen atom at the 6-position ring at...	08/22/2006
7022664	1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones The invention relates to 1,2-substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones and to the use of these compounds in fragrance compositions. ...	04/04/2006
7014925	Heterogeneous spiro compounds in organic light emitting device elements A family of non-polymeric heterogeneous spiro compounds having visible light emissive, hole-transport, electron transport or bipolar-transport properties may be used in organic light emitting devices (OLEDs), as an emissive layer in the OLEDs and/or in one or more o...	03/21/2006
7015247	Ibuprofen-aspirin, hydroxymethylacylfulvene analogs and L-sugar illudin analogs Ibuprofen-aspirin compounds useful in treating aspirin or ibuprofen-treatable conditions, hydroxymethylacylfulvene analogs useful as antitumor drugs, and L-sugar illudin analogs useful as antitumor drugs. ...	03/21/2006
7008568	Photochromic naphthopyran compounds: compositions and articles containing those naphthopyran compounds A photochromic naphthopyran displays good color distribution when the naphthopyran has a central nucleus of the formula: wherein F is a 5-member, 6-member, or 7-member heterocyclic ring group ha...	03/07/2006
6951943	Process for the preparation of phenylalanine enamide derivatives A process for the preparation of a class of phenylalanine enamide derivatives is described: wherein: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a linker ...	10/04/2005
6908918	Antitumor agents The present invention provides compounds of general formula I or II: wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defined in...	06/21/2005
6736998	Indeno-fused photochromic naphthopyrans Described are novel reversible photochromic indenonaphthopyran compounds, examples of which are 2H-naphtho[1,2-b]pyrans characterized by having a substituted or unsubstituted indeno group fused at the 2,3 positions of the group to the 1 side of the 2H-naphthopyran. ...	05/18/2004
6683709	Photochromic pyran compounds Photochromic pyran compounds and their use in synthetic resin objects of all types, especially for ophthalmic applications, particularly spiro compounds having a fluorene structure derived from naphthopyrans, which are known as spirofluorenopyrans. By int...	01/27/2004
6632788	Polyalkylbicylic derivatives The compound according to the formula set forth below ##STR1## where A is ##STR2## B is ##STR3## or A and B together form the ring structure ##STR4## and X, R' and R are independently H and CH3 and m=0 or 1. and the use of the compound in ...	10/14/2003
6558583	Naphthopyrans annelated in C5-C6 with a dihydrobenzo-cycloheptatriene-type carbocycle and compositions and matrices containing them The invention relates to novel naphthopyran-type compounds, which are annelated in position C5 -C6 with a seven-membered carbocycle, and which are of formula (I) given below: ##STR1## These compounds (I) possess interesting photochro...	05/06/2003
6555028	Polymeric matrix compatibilized naphthopyrans Described are polymeric matrix compatibilized naphthopyran compounds, examples of which are certain 2H-naphtho[1,2-b]pyrans, 3H-naphtho[2,1-b]pyrans and indeno[2,1-f]naphtho[1,2-b]pyrans each having at least one substituent containing terminal and/or pend...	04/29/2003
6509481	Tetrahydrofuran compounds having alicyclic structure Tetrahydrofuran compounds of formula (1) wherein the broken line represents a single bond, a divalent organic group, or a structure in which the alicyclic structure in the form of norbornene or tetracyclo[4.4.0.12,5.17,10 ]dodecene a...	01/21/2003
6506322	Naphthopyrans annelated in C5-C6 with an indene- or dihydronaphthalene-type carbocycle, and compositions and (co)polymer matrices containing them The present invention relates to novel naphthopyran-type compounds, annelated in position C5 -C6 by an indene- or dihydronaphthalene-type carbocycle, which are of the formulae (I) and (II) given below: ##STR1## These compounds (...	01/14/2003
6469076	Chromene compounds A photochromic compound which by itself develops a color tone of a neutral tint, exhibits a large fading rate and offers a good photochromic light resistance. A novel chromene compound has a basic structure as shown below in which a condensed ring formed ...	10/22/2002
6458801	Benzofurane derivatives, preparation method, use as medicines and pharmaceutical compositions containing same A compound of the formula ##STR1## wherein the substituents are as defined in the specification and its pharmaceutically acceptable salts and its prodrug useful for treating osteoporosis....	10/01/2002
6420334	Tetracyclic acetals 2-Alkoxydecahydro-2,3a,4,4,7-pentamethyl-3,7a-methano-7aH-indeno[5,6-b]fura ns are valuable novel woody fragrances for the preparation of perfume oils....	07/16/2002
6410754	Photochromic spiropyrans, and compositions and articles containing same Novel spiropyran compounds, particularly with photochromic properties, are disclosed, as well as photochromic compositions and ophthalmic articles containing said compounds. The photochromes have been designed so as to have a high colorability, a high sen...	06/25/2002
6387892	Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI Novel compounds having the Formulas 1 through 8, wherein the symbols have the meaning defined in the specification, and certain previously known compounds have been discovered to act as inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme...	05/14/2002
6380246	Alkyl-dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides The present invention relates to new compounds of the formula (I) ##STR1## in which X represents halogen, Y represents halogen or alkyl and Z represents halogen or alkyl, with the proviso that always one of the radicals Y and Z represents halogen while the oth...	04/30/2002
6353102	Photochromic naphthopyrans Described are novel photochromic naphtho[1,2-b]pyran compounds having certain substituents at the 2 position of the pyran ring, certain substituents at the 5 and 6 positions and optionally at the 7, 8, 9 and 10-positions of the naphtho portion of the comp...	03/05/2002
6340765	Chromene compound A photochromic compound having a high color-developing sensitivity, a large fading rate and good durability of photochromic property. A novel chromene compound is, for example, represented by the following formula, ##STR1## and in which, as a basic struct...	01/22/2002
6258775	Bi-aromatic compounds, pharmaceutical and cosmetic compositions containing same and uses The invention relates to novel biaromatic compounds having general formula I ##STR1## and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for treating dermatological, rheumatic, respiratory, cardiovasc...	07/10/2001
6252090	Compounds having activity as inhibitors of cytochrome P450RAI Compounds having Formula 1 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##...	06/26/2001
6210608	Naphthopyrans and phenanthropyrans annelated in C5-C6 with a bicycle group and compositions and (co) polymer matrices containing them The invention relates to novel naphthopyran- and phenanthropyran-type compounds having a carbobicycle annelated in 5,6-position. These compounds have formula (I) given below: ##STR1## These compounds (I) have interesting photochromic properties. The inven...	04/03/2001
6197225	Chromene compound A photochromic compound featuring a large fading rate to prevent a change in the color tone at the time of fading, exhibiting little color after aged, and exhibiting good durability in the photochromic property. The photochromic compound is a novel chrome...	03/06/2001
6166034	Spiro piperidine derivatives as 5HT1D receptor antagonists Novel spiro piperdine derivatives of formula (I), in which P1, P2, R1, R2, R2 ', R3, m, A, E, G, X, Y, R7, R8, R9 and R10 have the meanings defined in...	12/26/2000
6143908	Process for preparation of 1,3-dioxolane-4-methanol compounds A process for preparing easily and economically a 1,3-dioxolane-4-methanol compound in a racemic form or an optically active form with high purity and in high yield. The process comprises reacting an alkali metal or alkaline earth metal salt of an alcohol...	11/07/2000
6121274	Dihydrobenzofurane The invention concerns componuds of formula (I), in which R1, R2, R3 and R4 have the meanings given in the description. The compounds are novel, effective PDE-inhibitors....	09/19/2000
6113814	Polymerizable polyalkoxylated naphthopyrans Described are novel photochromic polymerizable polyalkoxylated naphthopyran compounds, examples of which are certain 2H-naphtho[1,2-b]pyrans, 3H-naphtho[2,1-b]pyrans and indeno[2,1-f]naphtho[1,2-b]pyrans each having at least one polyalkoxylated substituen...	09/05/2000
6096246	Photochromic naphthopyrans, compositions and articles containing them The invention relates to photochromic compounds of general formula (I), in which: R3 and R5 are C1-C6 alkoxy groups and the rest of the R groups represent various substituents. ##STR1##...	08/01/2000
6060600	Substituted tetronic acids useful for treating HIV and other retroviruses This application discloses novel tetronic acids for the treatment of AIDS and other diseases caused by retroviruses....	05/09/2000
6054475	Substituted dihydrobenzofuran-based phosphodiesterase 4 inhibitors useful for treating airway disorders Compounds of formula (I) ##STR1## and the salts of these compounds, are efficacious PDE (phosphodiesterase) inhibitors....	04/25/2000
6018059	(Benzofuran) naphthopyrans, the compositions and (co)polymer matrices containing them The present invention has for subjects novel compounds of the [benzofuran]naphthopyran type as well as the compositions and (co)polymer matrices containing them. Said compounds possess interesting photochromic properties....	01/25/2000

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Class 549/331 - The spiro includes a hetero ring