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| Number | Title | Issue Date |
| 7745647 | Diterpenes from the fruiting body of and pharmaceutical compositions thereof The present invention relates to novel diterpene compounds isolated from the fruiting body of Antrodia camphorata, especially to the new compounds of following structural formula: and pharmaceutically acceptable salt... | 06/29/2010 |
| 7601854 | Diterpenes from the fruiting body of and pharmaceutical compositions thereof The present invention relates to novel diterpene compounds isolated from the fruiting body of Antrodia camphorata, especially to the new compounds of following structural formula: and pharmaceutically acceptable salt... | 10/13/2009 |
| 7405226 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, card... | 07/29/2008 |
| 7341818 | Norbornene-type monomers and polymers containing pendent lactone or sultone groups The disclosed invention relates to novel norborne-type monomers containing pendent lactone or sultone groups. The invention also relates to norborne-type polymers and copolymers containing pendent lactone or sultone groups. These polymers and copolymers are useful i... | 03/11/2008 |
| 7316884 | 5-methylene-1,3-dioxolan-4-one derivatives, process for their production, polymers of the derivatives, resist compositions, and pattern formation process A 5-methylene-1,3-dioxolan-4-one derivative and a monomer and copolymer thereof and a resist composition containing the polymer or copolymer where the 5-methylene-1,3 -dioxolan-4-one derivative is of formula (1): ... | 01/08/2008 |
| 7317039 | Deuterated substituted dihydrofuranones and medicaments containing these compounds The invention concerns deuterated substituted dihydrofuranones and pharmaceuticals containing these compounds. In addition, the invention concerns the use of deuterated substituted dihydrofuranones for the treatment of symptoms for the irritating states of de... | 01/08/2008 |
| 7232930 | Compounds and methods for preparing methanesulfonamides A process for preparing (S)-(−)-N-[4-[4-[ethyl(6-fluoro-6-methylheptyl)amino]-1-hydroxy]phenyl]methanesulfonamide hemifumarate salt, which comprises reacting N-[4-[(2S)-tetrahydro-5-hydroxy-2-furanyl]phenyl]methanesulfonamide(IIa) with fluoroamine (III) in the pre... | 06/19/2007 |
| 7153982 | Method for the production of a phenolic substance from wood A method for the production of hydroxymatairesinol or a hydroxymatairesinol complex from wood, including the steps of a) extracting finely divided wood material with a polar solvent, b) optionally concentrating the extract by separating at least part of the solvent,... | 12/26/2006 |
| 7144876 | 3,5-Disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof Disclosed are 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, R2, A, B and D are defined herein. The present invention relates to the di... | 12/05/2006 |
| 7101654 | Norbornene-type monomers and polymers containing pendent lactone or sultone groups The disclosed invention relates to novel norbornene-type monomers containing pendent lactone or sultone groups. The invention also relates to norbornene-type polymers and copolymers comprising one or more repeating units represented by the formula: | 09/05/2006 |
| 7071339 | Process for preparing functionalized γ-butyrolactones from mucohalic acid A process for preparing functionalized γ-butyrolactones 3 and various biologically active compounds using mucohalic acid 1 and halide 2 in the presence of indium is disclosed, wherein X, Y, R1, R2, and R3 may have any of the meaning... | 07/04/2006 |
| 6960573 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same Compounds expressed by the following general formula (1), [wherein, R01 and R02 are each independently a hydrogen atom or a protecting group for a hydroxyl group; Z is one out of the following for... | 11/01/2005 |
| 6949684 | Process for preparing 1,2,4-butanetriol An object of the present invention is to provide a process wherein 1,2,4-butanetriol can be obtained safely, easily and inexpensively without causing problems concerning wastewater. A malic diester, 3-hydroxy-γ-butyrolactone or 3,4-dihydroxybutanoate represented by... | 09/27/2005 |
| 6949536 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents This invention provides a compound of the formula: or its pharmaceutically acceptable salt thereof, wherein A is partially unsaturated or unsaturated five membered heterocyclic, or partially unsaturated or unsaturated ... | 09/27/2005 |
| 6936447 | Autoinducer molecule Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the ... | 08/30/2005 |
| 6919465 | Method of preparing (3R, 3aS, 6aR)-3-hydroxyhexahydrofuro[2,3,-b] furan and related compounds A method of synthesizing (3R,3aS,6aR)-3-hydroxyhexahydrofuro[2,3-b]furan (I), and related compounds, in high yield and high enantiomeric selectivity is disclosed. Also disclosed is a method of manufacturing (5S)-5-(ben... | 07/19/2005 |
| 6906051 | Lactone integrin antagonists The present invention relates to a class of compounds represented by the Formula I: or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selec... | 06/14/2005 |
| 6833460 | Preparation and use of gamma-butyrolactones as cross-linking agents The rate of aminolysis of butyrolactones is predictably adjusted by attaching a substituent having a known field effect value (F) to the alpha position before reacting the substituted buytrolactone with an amine. The aminolysis product is a gamma-hydroxy amide. The ... | 12/21/2004 |
| 6818780 | P-hydroxyphenyl propionic acid derivatives as antiproliferative agents Derivatives of the compound p-hydroxyphenyl propionic acid characterised by those derivatives having the general formulas (I) and (Ia), where n can take the values 1,2,3; R can be H or CH3 and R1 can be CH3 or H with pharmacological ... | 11/16/2004 |
| 6787655 | Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, the transitio... | 09/07/2004 |
| 6730798 | Process for the preparation of substituted octanoyl amides Compounds of formula (II) are simultaneously halogenated in the 5 position and hydroxylated in the 4 position under lactonization, the halolactone is converted into a hydroxylactone and then the hydroxy group into a leaving group, the leaving group is replaced with ... | 05/04/2004 |
| 6727238 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents This invention provides a compound of the formula: or its pharmaceutically acceptable salt thereof, wherein A is partially unsaturated or unsaturated five membered heterocyclic, or partially unsaturated or unsaturated fi... | 04/27/2004 |
| 6720327 | Lactone integrin antagonists The present invention relates to a class of compounds represented by the Formula I. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selecti... | 04/13/2004 |
| 6696217 | Photosensitive monomer, photosensitive polymer and chemically amplified resist composition comprising lactone group having acid-labile protecting group A photosensitive monomer including a methylene butyrolactone derivative represented by the following formula: ##STR1## wherein R1 is a hydrogen atom or alkyl group, R2 is an acid-labile group, X is a hydrogen atom, or substituted or ... | 02/24/2004 |
| 6673818 | Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more fluoro-substituted benzenesulfonyl compounds corresponding to Formula I: ##STR1## wherein A, X, n, R1... | 01/06/2004 |
| 6660448 | Polymer, resist composition and patterning process The invention provides a polymer comprising recurring units containing bridged aliphatic rings in the backbone and having a hydroxyl, acyloxy or alkoxylcarbonyloxy group as well as a lactone structure bonded through a spacer, the polymer having a weight a... | 12/09/2003 |
| 6630596 | Composition and emulsifier The invention relates to an adduct of polyalk(en)yl succinic anhydride and a compound of formula (I): wherein R1 is hydrogen, hydroxyl, hydrocarbyl, hydroxyhydrocarbyl, carbamyl, 1-acetyl, amino, or nitro; R2 is hydrogen, hydroxyl, h... | 10/07/2003 |
| 6576662 | Compounds having anticancer activity : process for their preparation and pharmaceutical compositions containing them The present invention relates to novel anticancer agents, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The present invention more particularly relates to novel derivatives ... | 06/10/2003 |
| 6566538 | Substituted oxygen alicyclic compounds, including methods for synthesis thereof The invention provides new methods for preparation of cyclic oxygen compounds, including 2,5-disubstituted tetrahydrofurans, 2,6-disubstituted tetrahydropyrans, 2,7-disubstituted oxepanes and 2,8-oxocanes. The invention also provides new cyclic oxygen com... | 05/20/2003 |
| 6559100 | 2-benzoyl-cyclohexane-1,3-diones Substituted 2-benzoylcyclohexane-1,3-diones of the formula I ##STR1## where: R1 and R2 are each hydrogen, mercapto, nitro, halogen, cyano, thiocyanato, C1 -C6 -alkyl, C1 -C6 -haloalkyl, C1 | 05/06/2003 |
| 6552031 | Synergistic analgesic combination of oxycodone and rofecoxib Disclosed is a pharmaceutical composition, comprising a combination of a dose of rofecoxib or a pharmaceutically acceptable salt thereof and a dose of oxcodone or a pharmaceutically acceptable salt thereof, said combination in an amount sufficient to prov... | 04/22/2003 |
| 6541647 | Methods of synthesis of substituted tetrahydrofuran compound The invention includes inter alia new methods for preparation of the pharmaceutically active compound 2-(4-fluorophenoxymethyl)-5-(4-N-hydroxyureidyl-1 -butynyl)-tetrahydrofuran and precursors thereof.... | 04/01/2003 |
| 6531460 | Vitamin D, derivatives and remedies for inflammatory respiratory diseases containing the same Compounds expressed by the following general formula (1), ##STR1## ##STR2## The compounds can be used as active ingredients of treating agents for inflammatory respiratory diseases, malignant tumors, rheumatoid arthritis, osteoporosis, diabetes melli... | 03/11/2003 |
| 6512127 | Process for the preparation of hydroxylactones The present invention is directed towards a process for the preparation of enantiomerically enriched 4-hydroxymethyl-γ-butyrolactone (I). By kinetic racemate cleavage of racemic epoxide of the general formula (II) ##STR1## wherein R represents a (C1... | 01/28/2003 |
| 6500961 | Lactone compounds having alicyclic structure and their manufacturing method Lactone compounds of formula (1) are useful as monomers to form base resins for use in chemically amplified resist compositions adapted for micropatterning lithography. ##STR1## R1 is H or C1-6 alkyl, R2 is H or an acyl or... | 12/31/2002 |
| 6488818 | Removal of impurities from 3-(2'-acetoxyethyl)-dihydro-2(3H)furanone A process for removing impurities from 3-(2'-acetoxyethyl)dihydro-2(3H)furanone (I), where the 3-(2'-acetoxyethyl)dihydro-2(3H)furanone containing the undesirable impurities is initially prepared in a manner known per se by acetylation of 3-(2'-hydro... | 12/03/2002 |
| 6465664 | Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, th... | 10/15/2002 |
| 6433197 | Substituted oxygen alicyclic compounds, including methods for synthesis thereof The invention provides new methods for preparation of cyclic oxygen compounds, including 2,5-disubstituted tetrahydrofurans, 2,6-disubstituted tetrahydropyrans, 2,7-disubstituted oxepanes and 2,8-oxocanes. The invention also provides new cyclic oxygen com... | 08/13/2002 |
| 6423850 | Preparation and use of gamma-butyrolactones as cross-linking agents The rate of aminolysis of butyrolactones is predictably adjusted by attaching a substituent having a known field effect value (F) to the alpha position before reacting the substituted buytrolactone with an amine. The aminolysis product is a gamma-hydroxy ... | 07/23/2002 |
| 6362346 | Process for the preparation of -methylene-γ-butyrolactone and -acetoxymethyl-γ-butyrolactone This invention pertains to a process for making -methylene-γ-butyrolactone by acid-catalyzed rearrangement of tetrahydro-3-furoic acid. In a further embodiment, when tetrahydro-3-furoic acid is treated with acetic anhydride and an acid cataly... | 03/26/2002 |
