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...that Kleenex tissue was originally designed to be a gas mask filter? It was developed at the beginning of World War I to replace cotton, which was then in short supply as a surgical dressing.
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| Number | Title | Issue Date |
| 8106219 | Organic compound and organic dye used in dye-sensitized solar cell A kind of organic compound and organic dye used in dye-sensitized solar cell thereof. In the present invention, we synthesize a series of novel organic compounds with the structure of donor-conjugated chain-acceptor (D-π-A). The electron donor and acceptor groups, ... | 01/31/2012 |
| 7838687 | Redox-active polymers and their applications The present invention provides a monomer comprising the structure: wherein R1 and/or R1′ are selected from the group consisting of MeO, EtO, COF3, SO4H, SO3−, SO | 11/23/2010 |
| 7354934 | Chemokine receptor binding heterocyclic compounds with enhanced efficacy The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and opt... | 04/08/2008 |
| 7354932 | Chemokine receptor binding heterocyclic compounds with enhanced efficacy The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and opt... | 04/08/2008 |
| 7238818 | Heterocyclic metallocenes and polymerization catalysts A new class of heterocyclic metallocenes, a catalytic system containing them and a process for polymerizing addition polymerizable monomers using said catalytic system are disclosed; the heterocyclic metallocenes correspond to the formula (I): YjR″... | 07/03/2007 |
| 7196108 | Bicyclic heterocycles for the treatment of diabetes and other diseases The invention relates to certain bicyclic heterocycles havng the structure shown below which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, and atherosclerosis. | 03/27/2007 |
| 7192982 | Modulators of peroxisome proliferator activated receptors Disclosed is a compound represented by Structural Formula (I): Ar is a substituted or unsubstituted aromatic group. Q is a covalent bond, —CH2— or —CH2CH2—; W is a substituted or unsubstituted alkylene or a substituted or uns... | 03/20/2007 |
| 7015243 | Cyclohexyl prostaglandin analogs as EP-receptor agonists The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EP4 agonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following... | 03/21/2006 |
| 6951878 | Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases) The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PT... | 10/04/2005 |
| 6800380 | Organometallic luminescent materials and organic electroluminescent device containing same An organometallic luminescent material comprising the compound of formula (I) of the present invention can emit pure blue light and have high thermal stability: wherein, M1 is a monovalent or tetravalen... | 10/05/2004 |
| 6790965 | Combinatorial dihydrobenzopyran library Combinatorial libraries are disclosed which are represented by Formula I: (T′—L)q—Ŝ—C(O)—L′—II′ I wherein: Ŝ is a solid support; T′—L— is an identifier residue; and —L′—II′ is a l... | 09/14/2004 |
| 6695978 | Mono-, oligo- and polymers of benzo[b]thiophene and 2,2'-bisbenzo[b]thiophene and their use as charge transport materials Conjugated mono-, oligo- and polymers of benzo[b]thiophene and bisbenzo[b]thiophene are useful as semiconductors or charge transport materials in optical, electrooptical or electronic devices including field effect transistors, electroluminescent, photovo... | 02/24/2004 |
| 6683192 | Small organic molecule regulators of cell proliferation A compound represented in general formula (X) and (XI): ##STR1##... | 01/27/2004 |
| 6635779 | Metallocene compounds, process for their preparation and their use in catalytic systems for the polymerization of olefins A class of metallocene compounds is disclosed having general formula (I) wherein Y is a moiety of formula (II) wherein A, B, and D, same or different from each other, are selected from an element of the groups 14 to 16 of the Periodic Table of the Element... | 10/21/2003 |
| 6605632 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them The invention concerns compounds of formula (I): R--A--R' wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the desc... | 08/12/2003 |
| 6583161 | Benzenesulfonamides and benzamides as therapeutic agents The invention provides compounds, compositions and methods relating to novel aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particul... | 06/24/2003 |
| 6525040 | Cyclic organoselenium compounds, their preparation and their uses The invention is directed to novel cyclic organoselenium compounds useful as antioxidants, pharmaceutical compositions containing them, and methods for their preparation.... | 02/25/2003 |
| 6492405 | Nitric oxide donors and pharmaceutical compositions containing them The present invention provides a compound containing at least one sulfhydryl group and at least one NO donor group, wherein said compound is a) a compound containing one or more sulfhydryl groups linked to at least one aromatic ring or a heteroaromatic ri... | 12/10/2002 |
| 6472488 | (Thio) (meth) acrylate monomers, intermediate compounds for the synthesis of these monomers, polymerizable compositions and polymers obtained, and their optical and ophthalmic uses Polymerizable compositions from novel monomers that correspond to the formula: ##STR1## in which: Z represents H or CH3 and X represents O or S, and Y is a 5- to 8-membered heterocycle consisting of hydrogen, carbon and sulphur atoms and at lea... | 10/29/2002 |
| 6444833 | Metallocene compounds, process for their preparation and their use in catalytic systems for the polymerization of olefins A class of metallocene compounds is disclosed having the general formula (I): ##STR1## wherein Y is a moiety of formula (II) ##STR2## wherein A, B and D, same or different from each other, are selected from an element of the groups 14 to 16 of the Pe... | 09/03/2002 |
| 6433188 | Fused heteroaromatic glucokinase activators Glucokinase activating amides as herein disclosed are useful for increasing insulin secretion in the treatment of type II diabetes.... | 08/13/2002 |
| 6391901 | Thrombin inhibitors This application relates to novel compounds of formula I (and their pharmaceutically acceptable salts), as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula I, and the ... | 05/21/2002 |
| 6380235 | Benzimidazolones and analogues The present invention provides compounds and pharmaceutical formulations useful as progesterone receptor agonists and antagonists and having the general formula: ##STR1## wherein: A is O, S, or NR4 ; B is a bond between A and C.dbd.Q, or the mo... | 04/30/2002 |
| 6369098 | Dithiolane derivatives The present invention describes methods for synthesizing novel dithiolane derivatives, ligands with high affinity for the nuclear hormone receptors, peroxisome proliferator-activated receptor-γ (PPARγ) and/or PPAR. Methods for using these compoun... | 04/09/2002 |
| 6323214 | Allosteric adenosine receptor modulators The present invention relates to compounds of formulas (IA), (IB), and (IC): ##STR1## the preparation thereof, pharmaceutical formulations thereof, and their use in medicine as allosteric adenosine receptor modulators for uses including protection ag... | 11/27/2001 |
| 6307062 | (Thio) (meth) acrylate monomers, intermediate compounds for the synthesis of these monomers, polymerisable compositions and polymers obtained, and their optical and ophthalmic uses The novel monomers correspond to the formula: ##STR1## in which: Z represents H or CH3 and X represents O or S, and Y is a 5- to 8-membered heterocycle consisting of hydrogen, carbon and sulphur atoms and at least two endocyclic sulphur atoms.... | 10/23/2001 |
| 6245828 | Polymerizable compositions based on epoxides The present invention is directed to polymerizable dental compositions containing a) 3 to 80 wt. % of cycloaliphatic epoxides; b) 0 to 80 wt. % of an epoxide or a mixture of epoxides which are different from a); c) 3 to 85 wt. % of a filer material; d) 0.... | 06/12/2001 |
| 6028069 | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter Cyclic sulphones of formula (I) are disclosed, in which: R1 and R2 each independently of one another stand for H, A, CF3, CH2 F, CHF2, C2 F5, Hal, OH, OA, NH2, NHA, NA... | 02/22/2000 |
| 6015808 | Synthesis of pharmaceutical compositions with lactams and ଲ-lactams/oxo thia azabicyclo compounds Pharmaceutical compositions with heretofore unknown and enhanced physical, chemical, and biological properties are prepared by combining known biologically active parent compounds with oxo thia azabicyclo compounds, such as lactam and ଲ-lactam compo... | 01/18/2000 |
| 5998408 | Triterpene derivatives with immunosuppressant activity The compounds of Formula I ##STR1## are useful as immunosuppressive agents.... | 12/07/1999 |
| 5972950 | 1,2-diarylmethylene derivatives, their methods of preparation and their uses in therapeutics The present invention relates to the derivatives of formula: ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.... | 10/26/1999 |
| 5955491 | Method for treating osteoporosis The present invention provides a cathepsin L inhibitor containing a compound of the formula: ##STR1## wherein R1 is a hydrogen atom or an arylalkyl, heterocyclic-alkyl or lower alkyl group which may be substituted; R2 and R... | 09/21/1999 |
| 5856503 | Aminoalkyl-substituted benzo-heterocyclic compounds Aminoalkyl-substituted benzo-heterocyclic compounds of the formula ##STR1## wherein M, Q, R and T are as defined in the specification, as well as acid addition salts thereof. These compounds are useful as cholesterol level lowering agents and as anti... | 01/05/1999 |
| 5728696 | Acaricidal, insecticidal and nematicidal substituted (hetero)arylalkyl ketone oxime O-ethers, processes for their preparation, agents containing them, and their use as pesticides Acaricidal, insecticidal and nematicidal substituted (hetero)arylalkyl ketone oxime O-ethers, processes for their preparation, agents containing them, and their use as pesticides. The invention relates to compounds of the formula ##STR1## in which Ar... | 03/17/1998 |
| 5718845 | Tricyanovinyl substitution process for NLO polymers Nonlinear optical compounds which contain a heteroaromatic ring and may further comprise a tricyanovinyl group attached to the heteroaromatic ring.... | 02/17/1998 |
| 5716624 | Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (1): ##STR1## in which X is one of the radicals: ##STR2## and are useful for the treatment of a wide variety of disease states, whether h... | 02/10/1998 |
| 5709867 | Polyaromatic amide compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic amides have the structural formula (I): ##STR1## wherein Z is a radical --CO--NH-- or --NH--CO--, and are useful for the treatment of a wide variety of disease states, whether human or vete... | 01/20/1998 |
| 5637262 | Photochromic substituted naphthopyran compounds Described are novel reversible photochromic 3H-naphtho[2,1-b]pyran compounds, of the following graphic formula: ##STR1## wherein R1 is hydrogen or alkyl, R2 is hydrogen or preferably a carboalkoxy group and R3 is hydr... | 06/10/1997 |
| 5591848 | Spiroconjugated charge-transfer dyes for optical applications New intramolecular charge-transfer organic dyes are described. The design of these molecules is based on the phenomenon of spiroconjugation, and it provides a modular approach to the preparation of unique materials with interesting optical properties. In ... | 01/07/1997 |
| 5514799 | 1,1-vinyl substituted nonlinear optical materials Nonlinear optical compounds having structures with delocalized resonance configurations corresponding to: ##STR1## wherein A1 and A2 are independently selected from electron withdrawing moieties; R1 and R2 ... | 05/07/1996 |
